Eckhart Sinder – Wikipedia

Posted on by
before-content-x4

Eckhart Sinder (* 1960 in Kiel) is a German neurologist, professor and chief physician for neurology in the Diakovere Friederikenstift Hannover. Sinder is known for his work in the field of multiple sclerosis, the Guillain-Barré syndrome and the adult polyglucosa disease.

after-content-x4

Sinder was approved in 1986 at the University of Lübeck to the doctor and to Dr. med. in Lübeck. His dissertation dealt with immunological aspects of epilepsy. He was a scientific assistant at the Hanover Medical School from 1987 to 1992. In 1992, specialist doctor recognition was identified as a neurologist in Hanover. In the same year he was appointed senior physician of the Bergmannsheil University Clinic in Bochum. In 1998 he habilitated with the topic “Cell activation mechanisms in the blood and liquor in the acute Guillain Barrè Syndrome and in multiple sclerosis” and became head of the focus of clinical neuroimmunology and experimental liquor diagnostics in the University Hospital Bergmannsheil and spokesman for the research group Multiple sclerosis at the Ruhr University Bochum. From 2004 to 2006 Sinder held an unscheduled professorship at the Ruhr University in Bochum and has held an unscheduled professorship at the Hanover Medical School since 2006. Since November 2005 he has been the chief physician of the neurological clinic in the Diakovere Friederikenstift. In 2010 to 2013 he was a medical director at the Diakoniekrankenhaus Friederikenstift, today Diakovere Friederikenstift. [first]

After his dissertation, Sinder dealt with clinical issues for multiple sclerosis (MS) and the Guillain-Barré syndrome (GBS) during the assistant activity at the Hanover Medical School. [2] [3] At the Ruhr University Bochum, he focused on the characterization of cell activation mechanisms in the blood and cerebrospinal fluid in inflammatory diseases of the nervous system. The cytokin expression and release and the characterization of lymphocyte subpopulations in blood and liquor was examined in particular in MS and the GBS and correlated with clinical data. [4] [5] Later, the importance of the chemokines and their receptors in the pathogenesis of the MS was also examined. [6] [7] Together with Focke Ziemsen and Matthias Vorgerd, studies on the adult polyglucosine disease with the detection of new tissues and enzyme defects in various tissues. [8] [9] In addition to clinical and laboratory work, the nervous system also deals with expert questions in the event of inflammatory diseases of the nervous system. [ten]

Books

  • Hela-Felicitas Peterseit, Eckhart Sinder, Manfred Wick (authors, ed.): Liquord diagnostics: Liquitue diagnostics and methodological catalog of the German Society for Liquord diagnostics and clinical neurochemistry. 1st edition. Springer, Berlin/ Heidelberg 2007, ISBN 978-3-540-39017-6.
  • Volker Limmroth, Eckhart Sinder, Karin Baum: Multiple sclerosis: pocket atlas special. 1st edition. Thieme, 2004, ISBN 3-13-133281-6. (1st Portuguese ed. 2006.)

Scientific Article

  1. ↑ E. Sindern Vita ( Memento of the Originals from February 24, 2017 in Internet Archive ) Info: The archive link has been used automatically and not yet checked. Please check original and archive link according to the instructions and then remove this note. @first @2 Template: Webachiv/Iabot/www.diakovere.de
  2. ↑ E. Sinder, J. Haas, E. Stark, U. Wurster: Early onset MS under the age of 16: clinical and paraclinical features. In: Acta Neurol Scand. 86, 1992, S. 280–284. doi:10.1111/j.1600-0404.1992.tb05086.x
  3. ↑ It is.furnn, J.. Das Akute Guillain-Barré-Syndrom. In: German medical leaf. 93rd year, issue 28/29, 1996, pp. 1895–1898.
  4. ↑ E. Sinder, K. Schweppe, L. M. Ossge, J. P. Malin: Potential role of transforming growth factor-ß1 in terminating the immune response in patients with Guillain-Barré syndrome. In: J Neurol. 243, 1996, S. 264–268.
  5. ↑ K. F. Haegele, C. A. Stueckle, J. P. Malin, E. Sinder: Increase of CD8+ T-effector memory cells in peripheral blood of patients with relapsing-remitting multiple sclerosis compared to healthy controls. In: J Neuroimmunol. 183, 2007, S. 168–174. DOI: 10.1016/J.Jneuroim. 2006.09.008
  6. ↑ It is a sin, scent, em. Expression of chemokine receptor CXCR3 on cerebrospinal fluid T-cells is related to active MRI lesion appearance in patients with relapsing-remitting multiple sclerosis. In: J Neuroimmunol. 131, 2002, S. 186–190.
  7. ↑ E. Sinder: Role of chemokines and their receptors in the pathogenesis of multiple sclerosis. In: Front Biosci. 9, 2004, S. 457–463.
  8. ↑ F. Ziemsen, E. Sinder, J.M. Schröder, Y. S. Shin, J. Zange, M. W. Kilimann, J. P. Malin, M. Vorgerd: Novel missense mutations in the glycogen branching enzyme gene in adult polyglucosan body disease (APBD). In: Ann Neurol. 47, 2000, S. 536–540.
  9. ↑ E. Sinder, F. Ziemsen, T. Ziemsen, T. Podskarbi, Y. Shin, F. Brasch, K.M. Müller, J. M. Schröder, J. P. Malin, M. Vorgerd: Adult polyglucosan body disease: A postmortem correlation study. In: Neurology. 61, 2003, S. 263–265.
  10. ↑ E. Sinder: Inflammatory diseases of the nervous system (chapter 6.2). In: E. Fritze, B. May (ed.): The medical assessment. 8. Edition. Steinkopf-Verlag, Darmstadt 2012.

after-content-x4