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(adsbygoogle = window.adsbygoogle || []).push({});after-content-x4And \u00c9l\u00e9ment Secis , from English himself leno c ysteine i nsertion s Tructure , is a cis-regulator of Messenger RNA long long of nucleotides characterized by its hairpin shape, or “tod-orchel”. This particular three-dimensional structure leads ribosomes to translate the codon UGA by an amino acid, selenocysteine, while it is normally codon- STOP Opal in the genetic code. The secure elements are therefore essential for the synthesis of selenoproteins, mainly enzymes from the oxid-reward family. In bacteria, secis elements appear shortly after the UGA codons whose translation they alter. Among archaea and eukaryotes, they are in the 3′-terminal region of messenger RNAs and can affect the meaning of several UGA codons. One of these secis elements is in the 5′-terminal region in Methanococcus , you phylum des Erycharchaet [ first ] , [ 2 ] . (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4The particular secondary structure of the secure elements stems from a sequence of nucleic bases presenting certain distinctive characteristics authorizing this decisive spatial configuration, in particular atypical appearances between pairs of puric bases – guanine and adenine – which are essential to the proper functioning of the secis element . [ 3 ] \u2191 M. Rother , A. Resch , R. Wilting and A. B\u00f6ck \u00ab Selenoprotein synthesis in archaea \u00bb, BioFactors (Oxford, England) , vol. 14, n you 1-4, 2001 , p. 75\u201383 (ISSN\u00a0 0951-6433, PMID\u00a0 11568443, read online , consulted the April 12, 2018 ) \u2191 \u2191 Andr\u00e9 Lambert , Alain Lescure and Daniel Gautheret \u00ab A survey of metazoan selenocysteine insertion sequences \u00bb, Biochemistry , vol. 84, n O 9, September 2002 , p. 953\u2013959 (ISSN\u00a0 0300-9084, PMID\u00a0 12458087, read online , consulted the April 12, 2018 ) (in) R Walczak, E Westhof, P Carbon et a Krol , ‘ A novel RNA structural motif in the selenocysteine insertion element of eukaryotic selenoprotein mRNAs \u00bb , RNA , vol. 4, April 2, 1996 , p. 367-379 ( read online ) (in) Andr\u00e9 Lambert, Alain Lescure and Daniel Gautheret , ‘ A survey of metazoan selenocysteine insertion sequences \u00bb , Biochemistry , vol. 84, n O 9, September 2002 , p. 953-959 (PMID\u00a0 12458087 , DOI\u00a0 10.1016\/S0300-9084(02)01441-4 , read online ) (in) Heiko Mix, Alexey V. Lobanov et vadim N. GladyShev , ‘ SECIS elements in the coding regions of selenoprotein transcripts are functional in higher eukaryotes \u00bb , Nucleic Acids Research , vol. 35, n O 2, December 14, 2006 , p. 414-423 (PMID\u00a0 17169995 , DOI\u00a0 10.1093 \/ NART \/ GKL1060 , read online ) (in) A. Cassago, E.M. Rodrigues, E.L. Priete, K.W. Gaston, J.D. Alfonzo M.P. Iribar, M.J. Berry, A.K. Cruz et O.H. Thiemannnn , ‘ Identification of Leishmania Selenoproteins and Secis Item \u00bb , Molecular and Biochemical Parasitology , vol. 149, n O 2, October 2006 , p. 128-134 (PMID\u00a0 16766053 , DOI\u00a0 10.1016\/j.molbiopara.2006.05.002 , read online ) (in) Tobias Mourier, Arnab Pain, Bart Barrell and Sam Griffiths-Jones , ‘ To selenocysteine \u200b\u200btrna and secis element in Plasmodium falciparum \u00bb , RNA , vol. 11, n O 2, 2005 , p. 119-122 (PMID\u00a0 15659354 , DOI\u00a0 10.1261\/rna.7185605 , read online ) (in) Gregory V. Kryukov, Sergi Castellano, Sergey V. Novoselov, Alexey V. Lobanov, Omid Zehtab, Roderic Guig\u00f3 et Vadim N. GladyShevv , ‘ Characterization of Mammalian Selenoproteomes \u00bb , Science , vol. 300, n O 5624, May 30, 2003 , p. 1439-1443 (PMID\u00a0 12775843 , DOI\u00a0 10.1126\/science.1083516 , read online ) (in) Gregory V. Kryukov et vadim n. GladyShev , ‘ The prokaryotic selenoproteome \u00bb , EMBO reports , vol. 5, n O 5, April 23, 2004 , p. 538-543 (PMID\u00a0 15105824 , DOI\u00a0 10.1038\/Sj.embor.7400126 , read online ) (in) Alain krol , ‘ Evolutionarily different RNA motifs and RNA\u2013protein complexes to achieve selenoprotein synthesis \u00bb , Biochemistry , vol. 84, n O 8, August 2002 , p. 765-774 (PMID\u00a0 12457564 , DOI\u00a0 10.1016\/S0300-9084(02)01405-0 , read online ) (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2en\/wiki32\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2en\/wiki32\/element-cecis-wikipedia\/#breadcrumbitem","name":"Element Cecis \u2014 Wikipedia"}}]}]