[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/11057#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/11057","headline":"\u7db2\u819c\u82bd\u7d30\u80de – \u30bf\u30f3\u30d1\u30af\u8cea – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","name":"\u7db2\u819c\u82bd\u7d30\u80de – \u30bf\u30f3\u30d1\u30af\u8cea – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","description":"before-content-x4 \u7db2\u819c\u82bd\u7d30\u80de\u9593\u30bf\u30f3\u30d1\u30af\u8cea\uff08PRB\u3001RB\uff09 \u591a\u304f\u306e\u816b\u760d\u3067\u4e71\u308c\u305f\u6a5f\u80fd\u3092\u5099\u3048\u305f\u816b\u760d\u5438\u5f15\u5668\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002 [\u521d\u3081] PRB\u306e\u975e\u5e38\u306b\u9069\u5207\u306a\u6a5f\u80fd\u306f\u3001\u7d30\u80de\u5468\u671f\u306e\u901a\u904e\u3092\u9045\u304f\u3059\u308b\u3053\u3068\u3067\u7d30\u80de\u306e\u6210\u9577\u3092\u9045\u304f\u3059\u308b\u3053\u3068\u3067\u3059\u3002 PRB\u306f\u3001\u3044\u308f\u3086\u308b\u30dd\u30b1\u30c3\u30c8\u30d7\u30ed\u30c6\u30a4\u30f3\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u5c5e\u3057\u307e\u3059\u3002\u5f7c\u3089\u306e\u30e1\u30f3\u30d0\u30fc\u306f\u3001\u4ed6\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7d50\u5408\u3059\u308b\u305f\u3081\u306e\u5206\u5b50\u888b\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002 [2] [3] \u30d2\u30c8\u4e73\u982d\u816b\u30a6\u30a4\u30eb\u30b9\u306b\u611f\u67d3\u3057\u305f\u7d30\u80de\u3067\u7523\u751f\u3055\u308c\u308b\u3088\u3046\u306a\u816b\u760d\u7523\u7269\u304cPRB\u306b\u7d50\u5408\u3059\u308b\u5834\u5408\u3001\u3053\u308c\u306f\u764c\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 after-content-x4 \u30d2\u30c8\u3067\u306f\u3001PRB\u306f\u67d3\u8272\u4f5313 Genlocus Q14.1-Q14.2\u306e\u9818\u57df\u306e\u907a\u4f1d\u5b50\u306b\u3088\u3063\u3066\u30b3\u30fc\u30c9\u5316\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u907a\u4f1d\u5b50\u306e\u4e21\u65b9\u306e\u5bfe\u7acb\u907a\u4f1d\u5b50\u304c\u5909\u7570\u3057\u3066\u3044\u308b\u5834\u5408\u3001\u7f79\u60a3\u3057\u305f\u60a3\u8005\u306f\u7db2\u819c\u82bd\u7d30\u80de\u816b\u3092\u767a\u75c7\u3059\u308b\u305f\u3081\u3001\u540d\u524d\u304c\u4ed8\u3051\u3089\u308c\u307e\u3059\u3002\u3053\u308c\u307e\u3067\u306e\u3068\u3053\u308d\u3001\u816b\u760d\u304c\u30d2\u30c8\u751f\u7269\u5168\u4f53\u306e\u7d30\u80de\u5468\u671f\u3092\u8abf\u7bc0\u3059\u308b\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306b\u816b\u760d\u3092\u767a\u75c7\u3059\u308b\u7406\u7531\u306f\u4e0d\u660e\u3067\u3057\u305f\u3002\u7db2\u819c\u82bd\u7d30\u80de\u816b\u306b\u306f2\u3064\u306e\u5f62\u614b\u304c\u3042\u308a\u307e\u3059\u3002\u4e21\u5074\u30d5\u30a1\u30df\u30ea\u30fc\u3068\u7247\u5074\u6563\u767a\u6027\u5909\u7570\u4f53\u3067\u3059\u3002\u6700\u521d\u306e\u30b1\u30fc\u30b9\u3067\u306f\u3001\u3055\u3089\u306a\u308b\u816b\u760d\u3092\u767a\u75c7\u3059\u308b\u30ea\u30b9\u30af\u306f\u3001\u5e73\u5747\u3057\u30666\u500d\u5927\u304d\u3044\u3067\u3059\u3002 [4] 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[5] \u816b\u760d\u7d30\u80de\u3067\u3057\u3070\u3057\u3070\u898b\u3089\u308c\u308b\u30d8\u30c6\u30ed\u63a5\u5408\u6027\uff08LOH\uff09\u306e\u55aa\u5931\u3067\u3042\u308bRB\u907a\u4f1d\u5b50\u306e\u76f4\u63a5\u7684\u306a\u7a81\u7136\u5909\u7570\u306f\u5fc5\u8981\u3042\u308a\u307e\u305b\u3093\u3002 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PRB\u306f\u3001\u7d30\u80de\u304cG1\u76f8\u3092S\u671f\u307e\u3067\u4ecb\u3057\u3066\u7d30\u80de\u5468\u671f\u3092\u901a\u904e\u3059\u308b\u306e\u3092\u9632\u3050\u3053\u3068\u306b\u3088\u308a\u3001\u7d30\u80de\u304c\u640d\u50b7\u3057\u305fDNA\u306e\u8907\u88fd\u304b\u3089\u4fdd\u8b77\u3057\u307e\u3059\u3002 [6]","datePublished":"2020-01-11","dateModified":"2020-01-11","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/de.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/de.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/11057","wordCount":1686,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4 \u7db2\u819c\u82bd\u7d30\u80de\u9593\u30bf\u30f3\u30d1\u30af\u8cea\uff08PRB\u3001RB\uff09 \u591a\u304f\u306e\u816b\u760d\u3067\u4e71\u308c\u305f\u6a5f\u80fd\u3092\u5099\u3048\u305f\u816b\u760d\u5438\u5f15\u5668\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u3059\u3002 [\u521d\u3081] PRB\u306e\u975e\u5e38\u306b\u9069\u5207\u306a\u6a5f\u80fd\u306f\u3001\u7d30\u80de\u5468\u671f\u306e\u901a\u904e\u3092\u9045\u304f\u3059\u308b\u3053\u3068\u3067\u7d30\u80de\u306e\u6210\u9577\u3092\u9045\u304f\u3059\u308b\u3053\u3068\u3067\u3059\u3002 PRB\u306f\u3001\u3044\u308f\u3086\u308b\u30dd\u30b1\u30c3\u30c8\u30d7\u30ed\u30c6\u30a4\u30f3\u30d5\u30a1\u30df\u30ea\u30fc\u306b\u5c5e\u3057\u307e\u3059\u3002\u5f7c\u3089\u306e\u30e1\u30f3\u30d0\u30fc\u306f\u3001\u4ed6\u306e\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u7d50\u5408\u3059\u308b\u305f\u3081\u306e\u5206\u5b50\u888b\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002 [2] [3] 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[4] 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L.\u30de\u30fc\u30d5\u30a3\u30fc\u3001W\u3002F\u3002\u30d9\u30cd\u30c7\u30a3\u30af\u30c8\uff1a \u7db2\u819c\u82bd\u7d30\u80de\u816b\uff1a\u30d2\u30c8\u816b\u760d\u5f62\u6210\u306e\u624b\u304c\u304b\u308a\u3002 \u306e\uff1a \u5316\u5b66\u3002 \u7b2c223\u5dfb\u3001\u756a\u53f74640\u30011984\u5e743\u6708\u3001pp\u30021028-1033\u3001 PMID 6320372 \uff08\u30ec\u30d3\u30e5\u30fc\uff09\u3002  \u2191 a b  M. Korenjak\u3001A\u3002Brehm\uff1a \u5206\u5316\u3068\u767a\u9054\u306b\u91cd\u8981\u306a\u907a\u4f1d\u5b50\u306e\u8ee2\u5199\u3092\u8abf\u7bc0\u3059\u308bE2F-RB\u8907\u5408\u4f53\u3002 \u306e\uff1a \u907a\u4f1d\u5b66\u3068\u767a\u9054\u306b\u304a\u3051\u308b\u73fe\u5728\u306e\u610f\u898b\u3002 \u7b2c15\u5dfb\u3001\u756a\u53f75\u30012005\u5e7410\u6708\u3001pp\u3002520\u2013527\u3001doi\uff1a 10.1016\/j.gde.2005.07.001 \u3001 PMID 16081278 \uff08\u30ec\u30d3\u30e5\u30fc\uff09\u3002  \u2191 a b c d \u305d\u3046\u3067\u3059 f  K.\u30df\u30e5\u30fc\u30f3\u30ac\u30fc\u3001P\u3002M\u3002\u30cf\u30a6\u30ea\u30fc\uff1a \u30d2\u30c8\u30d1\u30d4\u30ed\u30fc\u30de\u30a6\u30a4\u30eb\u30b9\u306e\u4e0d\u6b7b\u5316\u3068\u5f62\u8cea\u8ee2\u63db\u6a5f\u80fd\u3002 \u306e\uff1a \u30a6\u30a4\u30eb\u30b9\u7814\u7a76\u3002 \u30d0\u30f3\u30c989\u3001\u756a\u53f72\u30012002\u5e7411\u6708\u3001213\u301c228\u30da\u30fc\u30b8\u3001 PMID 12445661 \uff08\u30ec\u30d3\u30e5\u30fc\uff09\u3002  \u2191  R. A.\u30af\u30e9\u30a4\u30f3\u30de\u30f3\u3001M\u3002A\u3002\u30bf\u30c3\u30ab\u30fcu\u3002 a\u3002\uff1a \u7db2\u819c\u82bd\u7d30\u80de\u816b\u306e\u9577\u671f\u751f\u5b58\u8005\u306b\u304a\u3051\u308b\u653e\u5c04\u7dda\u7642\u6cd5\u5f8c\u306e\u65b0\u3057\u3044\u764c\u306e\u30ea\u30b9\u30af\uff1a\u62e1\u5f35\u3055\u308c\u305f\u8ffd\u8de1\u3002 \u306e\uff1a Journal of Clinical Oncology\u3002 \u30d0\u30f3\u30c923\u3001\u756a\u53f710\u30012005\u5e744\u6708\u3001pp\u30022272\u20132279\u3001doi\uff1a 10.1200\/jco.2005.05.054 \u3001 PMID 15800318 \u3002  \u2191  A. G. 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