[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/22630#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/22630","headline":"\u30d4\u30ec\u30f3\u30bc\u30d4\u30f3 – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","name":"\u30d4\u30ec\u30f3\u30bc\u30d4\u30f3 – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","description":"before-content-x4 \u69cb\u9020\u5f0f \u5168\u822c\u7684 Freiname Pirenzepin \u4ed6\u306e\u540d\u524d 11- [\uff084-\u30e1\u30c1\u30eb\u30d4\u30da\u30e9\u30b8\u30f3-1-\u30a4\u30eb\uff09\u30a2\u30bb\u30c1\u30eb] 6,11-\u30b8\u30d2\u30c9\u30ed-5 h -pyrido [2.3- b ] [1,4] Benzodiazepin-6-on\uff08IUPAC\uff09 Pirencepinum\uff08\u30e9\u30c6\u30f3\uff09 \u30de\u30c3\u30b7\u30e5\u30d5\u30a9\u30fc\u30df\u30e5\u30e9 c 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    (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4\u69cb\u9020\u5f0f  \u5168\u822c\u7684 Freiname Pirenzepin \u4ed6\u306e\u540d\u524d 11- [\uff084-\u30e1\u30c1\u30eb\u30d4\u30da\u30e9\u30b8\u30f3-1-\u30a4\u30eb\uff09\u30a2\u30bb\u30c1\u30eb] 6,11-\u30b8\u30d2\u30c9\u30ed-5 h -pyrido [2.3- b ] [1,4] Benzodiazepin-6-on\uff08IUPAC\uff09 Pirencepinum\uff08\u30e9\u30c6\u30f3\uff09 \u30de\u30c3\u30b7\u30e5\u30d5\u30a9\u30fc\u30df\u30e5\u30e9 c 19 h 21 n 5 o 2 \u5916\u90e8\u8b58\u5225\u5b50\/\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9  \u85ac ATC\u30b3\u30fc\u30c9 A02 BX03  \u30a2\u30af\u30c6\u30a3\u30d6\u306a\u6210\u5206\u30af\u30e9\u30b9        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Ulkusttherapeutic \u6a5f\u69cb \u30e0\u30b9\u30ab\u30ea\u30f3\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u53d7\u5bb9\u4f53\u963b\u5bb3\u5264 \u7279\u6027 \u30e2\u30eb\u8cea\u91cf 351.40 g\u30fbmol -1 \u878d\u70b9 226\u2013228\u00b0C [\u521d\u3081] 250\u301c252\u00b0C \uff08dihydrochlorid-monohydrat\uff09 [2] \u5b89\u5168\u306b\u3064\u3044\u3066\u306e\u6848\u5185  \u6bd2\u6027\u30c7\u30fc\u30bf 427 mg\u30fbkg -1 \uff08Ld 50 \u3001\u30de\u30a6\u30b9\u3001i.p\u3002\uff09 [4] 156 mg\u30fbkg -1 \uff08Ld 50 \u3001\u30de\u30a6\u30b9\u3001i.v\u3002\uff09 [5] 3046 mg\u30fbkg -1 \uff08Ld 50 \u3001\u30de\u30a6\u30b9\u3001\u53e3\u982d\uff09 [5] 96 mg\u30fbkg -1 \uff08Ld 50 \u3001\u30de\u30a6\u30b9\u3001i.v\u3002\uff09 [5] \uff08dihydrochlorid\uff09 2600 mg\u30fbkg -1 \uff08Ld 50 \u3001\u30de\u30a6\u30b9\u3001\u53e3\u982d\uff09 [5] \uff08dihydrochlorid\uff09 92 mg\u30fbkg -1 \uff08Ld 50 \u3001\u30e9\u30c3\u30c8\u3001i.v\u3002\uff09 [5] \uff08dihydrochlorid\uff09 5000 mg\u30fbkg -1 \uff08Ld 50 \u3001\u30ae\u30a2\u3001\u3069\u3053\u3067\u3082\uff09 [5] \uff08dihydrochlorid\uff09 62,5 mg\u30fbkg -1 \uff08Ld 50 \u3001\u72ac\u3001i.v\u3002\uff09 [5] \uff08dihydrochlorid\uff09 > 3700 mg\u30fbkg -1 \uff08Ld 50 \u3001\u72ac\u3001\u53e3\u982d\uff09 [5] \uff08dihydrochlorid\uff09 \u53ef\u80fd\u306a\u9650\u308a\u4e00\u822c\u7684\u306b\u3001SI\u30e6\u30cb\u30c3\u30c8\u304c\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u7279\u306b\u660e\u8a18\u3057\u306a\u3044\u9650\u308a\u3001\u63d0\u4f9b\u3055\u308c\u305f\u30c7\u30fc\u30bf\u306f\u6a19\u6e96\u6761\u4ef6\u306b\u9069\u7528\u3055\u308c\u307e\u3059\u3002 Pirenzepin \uff08\u30d6\u30e9\u30f3\u30c9\u540d\uff1a \u30ac\u30b9\u30c8\u30ed\u30bc\u30d4\u30f3 \u00ae \u3001\u88fd\u9020\u696d\u8005\uff1aBoehringer Ingelheim\uff09\u3001\u526f\u4ea4\u611f\u795e\u7d4c\u7cfb\u306e\u30b0\u30eb\u30fc\u30d7\u304b\u3089\u306e\u7269\u8cea\u306f\u3001\u30e0\u30b9\u30ab\u30ea\u30f3\u6027\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u53d7\u5bb9\u4f53\u3092\u963b\u5bb3\u3057\u3001M\u306b\u5bfe\u3057\u3066\u7279\u306b\u9ad8\u3044\u89aa\u548c\u6027\u3092\u6301\u3063\u3066\u3044\u307e\u3059 \u521d\u3081  – \u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u53d7\u5bb9\u4f53\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Pirencepine\u306f\u3001M\u306e\u963b\u5bb3\u3067\u3042\u308b\u305f\u3081\u3001\u80c3\u9178\u5206\u6ccc\u3092\u6e1b\u3089\u3059\u305f\u3081\u306b\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002 \u521d\u3081  – \u8178\u7403\u83cc\u69d8\u7d30\u80de\u306e\u30c8\u30ec\u30bb\u30d7\u30bf\u30fc\u306f\u3001\u30d2\u30b9\u30bf\u30df\u30f3\u306e\u653e\u51fa\u304c\u5c11\u306a\u304f\u306a\u308a\u3001\u80c3\u9178\u5206\u6ccc\u304c\u6e1b\u5c11\u3057\u307e\u3059\u3002 100\u301c150 mg\/\u65e5\u306e\u901a\u5e38\u306e\u7528\u91cf\u3067\u3001\u30d4\u30ec\u30f3\u30bb\u30d4\u30f3\u306fM\u3092\u963b\u5bb3\u3057\u307e\u3059 3  – \u53e3\u8154\u3084\u983b\u8108\u306a\u3069\u306e\u5178\u578b\u7684\u306a\u6297\u30b3\u30ea\u30f3\u4f5c\u7528\u52b9\u679c\u3092\u5099\u3048\u305f\u982d\u9802\u7d30\u80de\u306e\u53d7\u5bb9\u4f53\u3067\u3042\u308b\u305f\u3081\u3001\u6f70\u760d\u7642\u6cd5\u3067\u306f\u3082\u306f\u3084\u5f79\u5272\u3092\u679c\u305f\u3057\u307e\u305b\u3093\u3002 [6] \u553e\u6db2\u306e\u6d41\u308c\u304c\u5897\u52a0\u3059\u308b\u3068\u3001\u76ae\u819a\u75c7\u306e\u4f7f\u7528\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002 [7] \u30d4\u30ec\u30f3\u30bb\u30d4\u30f3\u3092\u691c\u67fb\u3057\u3066\u3001\u8fd1\u8996\uff08\u8fd1\u8996\uff09\u3092\u6cbb\u7642\u3057\u307e\u3057\u305f\u3002 [8] \u30d1\u30a4\u30ec\u30f3\u30bb\u30d4\u30f3\u5408\u6210\u306f5\u3064\u306e\u30b9\u30c6\u30c3\u30d7\u3067\u884c\u308f\u308c\u307e\u3059\u3002 [5] \u6700\u521d\u306e\u30b9\u30c6\u30c3\u30d7\u3067\u306f\u3001\u5bfe\u5fdc\u3059\u308b\u30d9\u30f3\u30be\u9178\u30c1\u30fc\u30e0\u306e2-\u30af\u30ed\u30ea\u30f3-3-\u30a2\u30e2\u30d4\u30ea\u30b8\u30f3\u30682-\u30cb\u30c8\u30ed\u30d9\u30f3\u30be\u30a4\u30eb\u5869\u5316\u7269\u304c\u5f62\u6210\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001Raney-nickel\u306e\u5b58\u5728\u4e0b\u3067\u3001\u30cb\u30c8\u30ed\u30d5\u95a2\u6570\u306f\u30a2\u30df\u30f3\u306b\u6c34\u7d20\u5316\u3055\u308c\u307e\u3059\u3002 5.11\u30c7\u30a3\u30d2\u30c9\u30ed6\u306e\u30ea\u30f3\u30b0\u9589\u9396 h -pyrido- [2.3- b ] [1,4]\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3-6-on\u306f\u3001200\u00b0C\u306e3\u756a\u76ee\u306e\u30b9\u30c6\u30c3\u30d7\u3067\u5b9f\u884c\u3055\u308c\u307e\u3059\u3002\u305d\u306e\u5f8c\u3001\u30b5\u30a4\u30c9\u30c1\u30a7\u30fc\u30f3\u306f\u3001\u5869\u5316\u30af\u30ed\u30e9\u30bb\u30c1\u30eb\u3092\u4f7f\u7528\u3057\u305f\u5b9f\u88c5\u306b\u3088\u3063\u3066\u5c0e\u5165\u3055\u308c\u307e\u3059\u3002\u6700\u5f8c\u306e\u30b9\u30c6\u30c3\u30d7\u3067\u306f\u30011-\u30e1\u30c1\u30eb\u30d4\u30da\u30e9\u30b8\u30f3\u3068\u306e\u7f6e\u63db\u53cd\u5fdc\u306b\u30bf\u30fc\u30b2\u30c3\u30c8\u63a5\u7d9a\u304c\u4e0e\u3048\u3089\u308c\u307e\u3059\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Gastricur\uff08D\uff09\u3001Gastrozepin\uff08D\uff09\u3001Ulcoprotect\uff08D\uff09 \u2191  \u7279\u8a31ZA695933DE1795183\uff08Thomae 1969\uff09\u3002  \u2191  \u3078\u306e\u30a8\u30f3\u30c8\u30ea Pirenzepin \u3002\u306e\uff1a \u30aa\u30f3\u30e9\u30a4\u30f3\u3067r\u00f6mpp\u3002 Georg Thieme Verlag\u30012015\u5e741\u670825\u65e5\u30a2\u30af\u30bb\u30b9\u3002  \u2191  \u30c7\u30fc\u30bf\u30b7\u30fc\u30c8 \u30d4\u30ec\u30f3\u30bc\u30d4\u30f3\u30b8\u30d2\u30c9\u30ed\u5869\u5316 2011\u5e746\u670816\u65e5\u306b\u30a2\u30af\u30bb\u30b9\u3057\u305fSigma-Aldrich\u3067\uff08 PDF \uff09\u3002  \u2191  \u3078\u306e\u30a8\u30f3\u30c8\u30ea \u30d4\u30ec\u30f3\u30bc\u30d4\u30f3 \u7c73\u56fd\u56fd\u7acb\u533b\u5b66\u56f3\u66f8\u9928\uff08NLM\uff09 \uff08\u30da\u30fc\u30b8\u306f\u4f7f\u7528\u3067\u304d\u306a\u304f\u306a\u308a\u307e\u3057\u305f \u3001\u30b3\u30f3\u30c6\u30f3\u30c4\u306fPubchem ID\u304b\u3089\u5229\u7528\u53ef\u80fd\u306b\u306a\u308a\u307e\u3057\u305f 4848 \uff09\uff09  \u2191 a b c d \u305d\u3046\u3067\u3059 f g h \u79c1  Axel Kleemann\u3001J\u00fcrgenEngel\u3001Bernd Kutscher\u3001Dietmar Reichert\uff1a \u533b\u85ac\u7269\u8cea\u3002 \u7b2c4\u7248\u3002 Thieme-Verlag\u3001Stuttgart 2000\u3001ISBN 1-58890-031-2\u306b2\u5dfb\u304c\u767b\u5834\u3057\u307e\u3057\u305f\u3002 2003\u5e74\u4ee5\u964d\u3001\u534a\u5e74\u3054\u3068\u306e\u8ffd\u52a0\u3068\u66f4\u65b0\u304c\u3042\u308a\u307e\u3059\u3002  \u2191  K. Actiories\u3001U\u3002F\u00f6rstermann\u3001F\u3002Hofmann\u3001W\u3002Forth\uff1a \u4e00\u822c\u7684\u304a\u3088\u3073\u7279\u5225\u306a\u85ac\u7406\u5b66\u3068\u6bd2\u7269\u5b66\u3002 9.\u30a8\u30c7\u30a3\u30b7\u30e7\u30f3\u3002 Elsevier\u306eUrban\uff06Fischer\u30012005\u5e74\u3001ISBN 3-437-42521-8\u3002  \u2191  S2K\u30ac\u30a4\u30c9\u30e9\u30a4\u30f3 \u904e\u654f \u3002\u30c9\u30a4\u30c4\u306e\u9f3b\u3068\u5589\u306e\u533b\u5b66\u3001\u982d\u9838\u90e8\u624b\u8853\uff08DGHNO KHC\uff09\u3002 2018\u5e749\u670816\u65e5\u3002  \u2191  \u30b8\u30a7\u30d5\u30ea\u30fc\u30fbJ\u30fb\u30a6\u30a9\u30fc\u30cc\u3001\u30af\u30ea\u30b9\u30c6\u30a3\u30fc\u30ca\u30fbB\u30fb\u30ea\u30f3\u30ba\u30ea\u30fcu\u3002 a\u3002\uff1a \u5b50\u4f9b\u306e\u8fd1\u8996\u306e\u9032\u884c\u3092\u9045\u3089\u305b\u308b\u305f\u3081\u306e\u4ecb\u5165\u3002 \u306e\uff1a \u7cfb\u7d71\u7684\u30ec\u30d3\u30e5\u30fc\u306e\u30b3\u30af\u30e9\u30f3\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3002 2021\u3001 PMID 31930781 \u3001doi\uff1a 10.1002\/14651858.cd004916.pub4 \u3002  \u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u5065\u5eb7\u554f\u984c\u3092\u6271\u3044\u307e\u3059\u3002\u5f7c\u306f\u4ed5\u3048\u307e\u3059 \u3044\u3044\u3048 \u81ea\u5df1\u8a3a\u65ad\u3068\u4ea4\u63db \u3044\u3044\u3048 \u533b\u5e2b\u306b\u3088\u308b\u8a3a\u65ad\u3002\u5065\u5eb7\u554f\u984c\u306b\u95a2\u3059\u308b\u30e1\u30e2\u306b\u6ce8\u610f\u3057\u3066\u304f\u3060\u3055\u3044\uff01       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki10\/archives\/22630#breadcrumbitem","name":"\u30d4\u30ec\u30f3\u30bc\u30d4\u30f3 – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2"}}]}]