[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/13312#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/13312","headline":"\u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0 – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","name":"\u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0 – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","description":"before-content-x4 \u69cb\u9020\u5f0f \u5168\u822c\u7684 Freiname \u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0 [\u521d\u3081] \u4ed6\u306e\u540d\u524d n – {[5-\uff082-\u30d5\u30eb\u30aa\u30eb\u30d5\u30a7\u30cb\u30eb\uff09-1-\u30e1\u30c1\u30eb-2,3-\u30b8\u30d2\u30c9\u30ed-1,4-\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3-2-\u30a4\u30eb]\u30e1\u30c1\u30eb}\u30c1\u30aa\u30d5\u30a7\u30f3-3-\u30ab\u30eb\u30dc\u30ad\u30b5\u30df\u30c9\uff08IUPAC\uff09 1-\u30e1\u30c1\u30eb-2-\uff083-\u30c1\u30a8\u30cb\u30eb\u30ab\u30eb\u30dc\u30cb\u30eb\uff09\u30a2\u30df\u30ce\u30e1\u30c1\u30eb-5-\uff082-\u30d5\u30eb\u30aa\u30eb\u30d5\u30a7\u30cb\u30eb\uff09 – h -2,3-\u30b8\u30d2\u30c9\u30ed-1,4-\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\uff08\u30e1\u30c3\u30b7\u30e5\uff09 \u30de\u30c3\u30b7\u30e5\u30d5\u30a9\u30fc\u30df\u30e5\u30e9 c 22 h 20 fn","datePublished":"2020-08-20","dateModified":"2020-08-20","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/1\/16\/Tifluadom_structure.svg\/222px-Tifluadom_structure.svg.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/1\/16\/Tifluadom_structure.svg\/222px-Tifluadom_structure.svg.png","height":"198","width":"222"},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/13312","wordCount":841,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4\u69cb\u9020\u5f0f  \u5168\u822c\u7684 Freiname \u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0 [\u521d\u3081] \u4ed6\u306e\u540d\u524d n  –  {[5-\uff082-\u30d5\u30eb\u30aa\u30eb\u30d5\u30a7\u30cb\u30eb\uff09-1-\u30e1\u30c1\u30eb-2,3-\u30b8\u30d2\u30c9\u30ed-1,4-\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3-2-\u30a4\u30eb]\u30e1\u30c1\u30eb}\u30c1\u30aa\u30d5\u30a7\u30f3-3-\u30ab\u30eb\u30dc\u30ad\u30b5\u30df\u30c9\uff08IUPAC\uff09 1-\u30e1\u30c1\u30eb-2-\uff083-\u30c1\u30a8\u30cb\u30eb\u30ab\u30eb\u30dc\u30cb\u30eb\uff09\u30a2\u30df\u30ce\u30e1\u30c1\u30eb-5-\uff082-\u30d5\u30eb\u30aa\u30eb\u30d5\u30a7\u30cb\u30eb\uff09 –  h -2,3-\u30b8\u30d2\u30c9\u30ed-1,4-\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\uff08\u30e1\u30c3\u30b7\u30e5\uff09 \u30de\u30c3\u30b7\u30e5\u30d5\u30a9\u30fc\u30df\u30e5\u30e9 c 22 h 20 fn 3 \u3042\u306a\u305f \u5916\u90e8\u8b58\u5225\u5b50\/\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9  \u85ac \u30a2\u30af\u30c6\u30a3\u30d6\u306a\u6210\u5206\u30af\u30e9\u30b9 \u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3 \u6a5f\u69cb        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u03baOpioid\u53d7\u5bb9\u4f53\u3078\u306e\u7d50\u5408 \u7279\u6027 \u30e2\u30eb\u8cea\u91cf 393.48 g\u30fbmol -1 \u5b89\u5168\u306b\u3064\u3044\u3066\u306e\u6848\u5185  \u53ef\u80fd\u306a\u9650\u308a\u4e00\u822c\u7684\u306b\u3001SI\u30e6\u30cb\u30c3\u30c8\u304c\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u7279\u306b\u660e\u8a18\u3057\u306a\u3044\u9650\u308a\u3001\u63d0\u4f9b\u3055\u308c\u305f\u30c7\u30fc\u30bf\u306f\u6a19\u6e96\u6761\u4ef6\u306b\u9069\u7528\u3055\u308c\u307e\u3059\u3002 \u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0 \u3053\u306e\u7269\u8cea\u30af\u30e9\u30b9\u306e\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u3092\u5099\u3048\u305f\u6cbb\u7642\u7684\u306b\u4f7f\u7528\u3055\u308c\u3066\u3044\u306a\u3044\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u8a98\u5c0e\u4f53\u3067\u3059\u3002 \u4ed6\u306e\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u3068\u306f\u5bfe\u7167\u7684\u306b\u3001\u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0\u306fGABA\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u307e\u305b\u3093 a -ID\u53d7\u5bb9\u4f53\u3067\u3042\u308b\u305f\u3081\u3001\u3053\u306e\u5e03\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5178\u578b\u7684\u306a\u6297\u4e0d\u5b89\u75c7\u3001\u93ae\u9759\u5264\u3001\u50ac\u7720\u8853\u3001\u4e2d\u592e\u7b4b\u8089\u306e\u7de9\u548c\u52b9\u679c\u306f\u767a\u751f\u3057\u307e\u305b\u3093\u3002\u30d9\u30f3\u30be\u30b8\u30a2\u30bc\u30d4\u30f3\u306e\u5869\u57fa\u6027\u69cb\u9020\u306f\u3001\u5bfe\u5fdc\u3059\u308b\u7f6e\u63db\u306b\u3088\u3063\u3066\u5909\u66f4\u3055\u308c\u3001\u7269\u8cea\u304c\u03ba\u53d7\u5bb9\u4f53\u306b\u5bfe\u3057\u3066\u9ad8\u3044\u89aa\u548c\u6027\u3092\u6301\u3064\u3088\u3046\u306b\u5909\u66f4\u3055\u308c\u307e\u3057\u305f\u3002 [3] \u30aa\u30d4\u30aa\u30a4\u30c9\u69d8\u52b9\u679c\u306e\u7d50\u679c\uff1a\u30c8\u30ea\u30d5\u30eb\u30a2\u30c9\u30e0\u306f\u3001\u52d5\u7269\u5b9f\u9a13\u306b\u304a\u3044\u3066\u9ad8\u3044\u93ae\u75db\u6027\u306e\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u307e\u3059\u3002 [4] \u5f37\u5316\u3055\u308c\u305f\u5229\u5c3f\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059 [5] \u98df\u6b32\u306e\u63d0\u6848\u3068\u540c\u69d8\u306b [6] [7] [8] \u93ae\u9759\u52b9\u679c\u304c\u3042\u308a\u307e\u3059\u3002\u307e\u305f\u3001\u672b\u68a2\u30b3\u30ec\u30b7\u30b9\u30c8\u30ad\u30cb\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3068\u3057\u3066\u3082\u6a5f\u80fd\u3057\u307e\u3059\u3002 [9]        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Tifluadom\u306f\u3053\u306e\u85ac\u3067\u306f\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u304c\u3001\u7814\u7a76\u3067\u4f7f\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002 \u03ba\u30a2\u30b4\u30cb\u30ba\u30e0\u306e\u305f\u3081\u3001\u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0\u306f\u30012006\u5e74\u306e\u8cbf\u6613\u306e\u85ac\u7269\u306b\u5339\u6575\u3059\u308b\u4e0d\u5feb\u611f\u3084\u5e7b\u899a\u306a\u3069\u306e\u4e0d\u5feb\u306a\u526f\u4f5c\u7528\u3092\u793a\u3057\u3066\u3044\u307e\u3059 Fortral \uff09\u304a\u3088\u3073\u7cbe\u795e\u6d3b\u6027\u30b5\u30eb\u30d3\u30ce\u30ea\u30f3A\u3001\u9ebb\u85ac\u306b\u95a2\u3059\u308bAZTEC\u306b\u3088\u3063\u3066\u8abf\u7bc0\u3055\u308c\u308b\u9ebb\u85ac\u306e\u4e3b\u306a\u6709\u52b9\u6210\u5206\u3002\u4e00\u65b9\u3001Tifluadom\u306e\u4f9d\u5b58\u6027\u306e\u53ef\u80fd\u6027\u306f\u3001\u308f\u305a\u304b\u306b\u9855\u8457\u3067\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002 [\u5341] \u2191  INN\u306e\u63a8\u5968\u30ea\u30b9\u30c823 \u3001\u4e16\u754c\u4fdd\u5065\u6a5f\u95a2\uff08WHO\uff09\u30019\u3002Juni1983\u3002  \u2191  \u3053\u306e\u7269\u8cea\u306f\u3001\u305d\u306e\u5371\u967a\u306e\u89b3\u70b9\u304b\u3089\u307e\u3060\u5206\u985e\u3055\u308c\u3066\u3044\u306a\u3044\u304b\u3001\u3053\u308c\u306e\u4fe1\u983c\u3067\u304d\u308b\u3068\u5f15\u7528\u3055\u308c\u305f\u30bd\u30fc\u30b9\u306e\u3044\u305a\u308c\u304b\u304c\u307e\u3060\u767a\u898b\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002  \u2191  D. Romer\u3001H\u3002H\u3002Buscher\u3001R\u3002C\u3002Hill\u3001R\u3002Maurer\u3001T\u3002J\u3002Petcher\u3001H\u3002Zeugner\u3001W\u3002Benson\u3001E\u3002Finner\u3001W\u3002Milkowski\u3001P\u3002W\u3002Thies\uff1a \u65e2\u77e5\u306e\u30af\u30e9\u30b9\u306e\u85ac\u7269\u306b\u304a\u3051\u308b\u4e88\u671f\u3057\u306a\u3044\u30aa\u30d4\u30aa\u30a4\u30c9\u6d3b\u6027\u3002 \u306e\uff1a \u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u3002 20\u201327; 31\uff0812\u201313\uff091982\u3001S\u30021217\u20131220\u3002  \u2191  R. F. Genovese\u3001L\u3002A\u3002Dykstra\uff1a \u30ea\u30b9\u30b6\u30eb\u306b\u304a\u3051\u308b\u96fb\u6c17\u30b7\u30e7\u30c3\u30af\u6ef4\u5b9a\u304a\u3088\u3073\u5c3e\u5438\u53ce\u624b\u9806\u306e\u4e0b\u3067\u306e\u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0\u306e\u5f71\u97ff\u3002 \u306e\uff1a \u30e9\u30a4\u30d5\u30b5\u30a4\u30a8\u30f3\u30b9\u3002 10; 39\uff0819\uff09\u30011986\u3001S\u30021713\u20131719\u3002  \u2191  J. D. Leander\uff1a \u30ab\u30c3\u30d1\u30aa\u30d4\u30aa\u30a4\u30c9\u30a2\u30b4\u30cb\u30b9\u30c8\u3068\u62ee\u6297\u85ac\uff1a\u98f2\u9152\u3068\u5c3f\u306e\u51fa\u529b\u3078\u306e\u5f71\u97ff\u3002 \u306e\uff1a \u98df\u6b32\u3002 5\uff081\uff09\u30011984\u3001S\u30027\u201314\u3002  \u2191  H. C.\u30b8\u30e3\u30af\u30bd\u30f3\u3001R\u3002D\u3002\u30b9\u30a6\u30a7\u30eb\uff1a \u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0\u8a98\u5c0e\u6804\u990a\u306b\u304a\u3051\u308b\u30aa\u30d4\u30aa\u30a4\u30c9\u53d7\u5bb9\u4f53\u30b5\u30d6\u30bf\u30a4\u30d7\u306e\u5f79\u5272\u3002 \u306e\uff1a Journal of Pharmacy and Pharmacology\u3002 36\uff0810\uff09\u30011984\u3001S\u3002683\u2013686\u3002  \u2191  L. A. Dykstra\u3001D\u3002E\u3002Gmerek\u3001G\u3002Winger\u3001J\u3002H\u3002Woods\uff1a \u30a2\u30ab\u30b2\u30b6\u30eb\u306e\u30ab\u30c3\u30d1\u30aa\u30d4\u30aa\u30a4\u30c9\u3002 I.\u5229\u5c3f\u3001\u93ae\u9759\u3001\u93ae\u75db\u3001\u8b58\u5225\u523a\u6fc0\u52b9\u679c\u3002 \u306e\uff1a Journal of Pharmacology and Experimental Therapeutics\u3002 242\uff082\uff09\u30011987\u3001S\u3002413\u2013420\u3002  \u2191  S. J.\u30af\u30fc\u30d1\u30fc\u3001W\u3002R\u3002\u30e0\u30fc\u30a2\u30ba\u3001A\u3002\u30b8\u30e3\u30af\u30bd\u30f3\u3001D\u3002J\u3002\u30d0\u30fc\u30d0\u30fc\uff1a \u30e9\u30c3\u30c8\u306e\u30af\u30ed\u30eb\u30c7\u30a3\u30a2\u30bc\u30dd\u30ad\u30b7\u30c9\u304a\u3088\u3073\u30ab\u30c3\u30d1\u30a2\u30b4\u30cb\u30b9\u30c8\u3068\u6bd4\u8f03\u3057\u305f\u98df\u7269\u6d88\u8cbb\u306b\u5bfe\u3059\u308b\u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0\u306e\u5f71\u97ff\u3002 \u306e\uff1a \u795e\u7d4c\u85ac\u7406\u5b66\u3002 1985\u5e749\u6708\u3001 PMID 2997653 \u3002  \u2191  R. S.\u30c1\u30e3\u30f3\u3001V\u3002J\u3002\u30ed\u30c3\u30c6\u30a3\u3001T\u3002B\u3002\u30c1\u30a7\u30f3\u3001M\u3002E\u3002\u30ad\u30fc\u30ac\u30f3\uff1a Kappa-opiate Agonist\u3067\u3042\u308bTifluadom\u306f\u3001\u672b\u68a2\u30b3\u30ec\u30b7\u30b9\u30c8\u30ad\u30cb\u30f3\u53d7\u5bb9\u4f53\u62ee\u6297\u85ac\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002 \u306e\uff1a \u795e\u7d4c\u85ac\u7406\u5b66\u3002 1985\u5e749\u6708\u3001 PMID 3027627 \u3002  \u2191  \u30b9\u30a4\u30f3\u30b0\uff1a \u5217\u9ebb\u85ac\u3002\u5e02\u5834\u30d5\u30a9\u30fc\u30e0\u3068\u30a2\u30af\u30b7\u30e7\u30f3\u30e2\u30fc\u30c9\u3002 Springer\u3001Heidelberg\/ Dordrecht\/ London\/ New York 2013\u3001ISBN 978-3-642-30162-9\u3001S\u3002716RN 3449\u3002  \u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u5065\u5eb7\u554f\u984c\u3092\u6271\u3044\u307e\u3059\u3002\u5f7c\u306f\u4ed5\u3048\u307e\u3059 \u3044\u3044\u3048 \u81ea\u5df1\u8a3a\u65ad\u3068\u4ea4\u63db \u3044\u3044\u3048 \u533b\u5e2b\u306b\u3088\u308b\u8a3a\u65ad\u3002\u5065\u5eb7\u554f\u984c\u306b\u95a2\u3059\u308b\u30e1\u30e2\u306b\u6ce8\u610f\u3057\u3066\u304f\u3060\u3055\u3044\uff01       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/13312#breadcrumbitem","name":"\u30c6\u30a3\u30d5\u30eb\u30a2\u30c9\u30e0 – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2"}}]}]