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[]).push({});after-content-x4\u9023\u90a6\u30ea\u30b9\u30af\u8a55\u4fa1\u7814\u7a76\u6240\u306f\u3001\u98df\u54c1\u4e2d\u306e5-HMF\u542b\u6709\u91cf\u306f\u300c\u73fe\u5728\u306e\u79d1\u5b66\u7684\u77e5\u8b58\u306b\u3088\u308b\u3068\u5065\u5eb7\u306e\u70b9\u3067\u554f\u984c\u306e\u306a\u3044\u300d\u3068\u8ff0\u3079\u305f\u3002 [4] \u4e3b\u306a\u9332\u97f3\u306f\u3001\u30b3\u30fc\u30d2\u30fc\u306e\u697d\u3057\u307f\u306b\u3064\u3044\u3066\u4f5c\u3089\u308c\u3066\u3044\u307e\u3059\u3002 \u3053\u306e\u6709\u6a5f\u5316\u5408\u7269\u306f\u30011895\u5e74\u306bG.d\u00fcll\u306b\u3088\u3063\u3066\u30d5\u30eb\u30af\u30c8\u30fc\u30b9\u307e\u305f\u306f\u30b7\u30e5\u30a6\u9178\u306b\u3088\u308b\u30b5\u30af\u30ab\u30ea\u30b9\u306e\u8131\u6c34\u75c7\u306b\u3088\u308a\u3001J\u3002Kiermeyer\u306b\u3088\u3063\u3066\u305d\u308c\u306b\u95a2\u4fc2\u306a\u304f\u3001\u6700\u521d\u306b\u78ba\u7acb\u3055\u308c\u307e\u3057\u305f\u3002 [5] [6] 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\u30e1\u30a4\u30e9\u30fc\u30c9\u53cd\u5fdc\u306f\u3001\u30a2\u30df\u30ce\u9178\u3068\u7802\u7cd6\u306e\u6e1b\u5c11\u306e\u9593\u306e\u5316\u5b66\u53cd\u5fdc\u3067\u3042\u308a\u3001\u65e5\u713c\u3051\u3057\u305f\u98df\u54c1\u306b\u72ec\u7279\u306e\u5473\u3092\u4e0e\u3048\u307e\u3059\u3002\u53cd\u5fdc\u306f\u975e\u9175\u7d20\u6027\u65e5\u713c\u3051\u306e\u4e00\u5f62\u614b\u3067\u3042\u308a\u3001\u901a\u5e38\u306f140\u00b0C\u304b\u3089165\u00b0C\uff08280\u301c330\u00b0F\uff09\u306b\u6025\u901f\u306b\u9032\u884c\u3057\u307e\u3059\u3002\u3088\u308a\u9ad8\u3044\u6e29\u5ea6\u3067\u306f\u3001\u30ab\u30e9\u30e1\u30eb\u5316\uff08\u7802\u7cd6\u306e\u8910\u5909\u3001\u9855\u8457\u306a\u30d7\u30ed\u30bb\u30b9\uff09\u3001\u304a\u3088\u3073\u71b1\u5206\u89e3\uff08\u6700\u7d42\u9084\u5143\u3001\u706b\u50b7\u306b\u3064\u306a\u304c\u308b\uff09\u304c\u3088\u308a\u9855\u8457\u306b\u306a\u308a\u307e\u3059\u3002 Maillard\u53cd\u5fdc\u306e\u6700\u7d42\u751f\u6210\u7269\u306e1\u3064\u306f\u30015-\u30d2\u30c9\u30ed\u30ad\u30b7\u30e1\u30c1\u30eb\u30d5\u30a1\u30bb\uff085-HMF\uff09\u3067\u3059\u3002 [7]        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u30d5\u30eb\u30af\u30c8\u30fc\u30b9\u304c\u52a0\u71b1\u3055\u308c\u308b\u3068\u3001\u30d5\u30eb\u30af\u30c8\u30fc\u30b9\u306fHMF\u3092\u5f62\u6210\u3057\u307e\u3059\u3002 Table of ContentsHONIG\u306eHMF [ \u7de8\u96c6 | \u30bd\u30fc\u30b9\u30c6\u30ad\u30b9\u30c8\u3092\u7de8\u96c6\u3057\u307e\u3059 ] \u4ed6\u306e\u98df\u54c1\u306eHMF\u542b\u6709\u91cf [ \u7de8\u96c6 | \u30bd\u30fc\u30b9\u30c6\u30ad\u30b9\u30c8\u3092\u7de8\u96c6\u3057\u307e\u3059 ] \u624b\u8853\u4e2d\u306e5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30e1\u30c1\u30eb\u6bdb\u76ae [ \u7de8\u96c6 | \u30bd\u30fc\u30b9\u30c6\u30ad\u30b9\u30c8\u3092\u7de8\u96c6\u3057\u307e\u3059 ] \u63a5\u7740\u5264\u306e\u751f\u7523\u306b\u304a\u3051\u308b\u4f7f\u7528\u306e\u53ef\u80fd\u6027 [ 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\u30bd\u30fc\u30b9\u30c6\u30ad\u30b9\u30c8\u3092\u7de8\u96c6\u3057\u307e\u3059 ] \u6bd4\u8f035-HMF\u5bfe\u30d3\u30bf\u30df\u30f3 [ \u7de8\u96c6 | \u30bd\u30fc\u30b9\u30c6\u30ad\u30b9\u30c8\u3092\u7de8\u96c6\u3057\u307e\u3059 ] HONIG\u306eHMF [ \u7de8\u96c6 | \u30bd\u30fc\u30b9\u30c6\u30ad\u30b9\u30c8\u3092\u7de8\u96c6\u3057\u307e\u3059 ] 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\u63a8\u5b9aHMF\u8a18\u9332\u306f4\u301c30 mg\/\u4eba\/\u65e5\u3067\u3042\u308a\u3001\u6642\u306b\u306f\u6700\u5927350 mg\u306b\u306a\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u3053\u306e\u5024\u306f\u975e\u73fe\u5b9f\u7684\u3067\u3059\u30022011\u5e74\u306b\u306f\u3001\u30c9\u30a4\u30c4\u306e\u30ea\u30b9\u30af\u8a55\u4fa1\u7814\u7a76\u6240\u3067\u3042\u308bBFR\u304c\u6b21\u306e\u8a55\u4fa1\u306b\u81f3\u308a\u307e\u3057\u305f\u3002 [4] 5-HMF\u306f\u3001\u7279\u5b9a\u306e\u98df\u54c1\u306a\u3069\u3067\u3082\u5927\u91cf\u306b\u767a\u751f\u3057\u307e\u3059\u3002\u30c9\u30e9\u30a4\u30d5\u30eb\u30fc\u30c425-2900 mg\/kg\u3001\u30ad\u30e3\u30e9\u30e1\u30eb\u88fd\u54c1110-9500 mg\/kg\u307e\u305f\u306f\u30b3\u30fc\u30d2\u30fc\uff08\u30a4\u30f3\u30b9\u30bf\u30f3\u30c8\uff09400-4100 mg\/kg\u3002 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\u5e73\u5747\u4f53\u91cd\u306f70 kg\u3067\u3001\u3053\u308c\u306f5600\u301c7000 mg\u3092\u610f\u5473\u3057\u307e\u3059\u3002 \u85ac\u7269\u52d5\u614b\u3068\u4ee3\u8b1d [ \u7de8\u96c6 | \u30bd\u30fc\u30b9\u30c6\u30ad\u30b9\u30c8\u3092\u7de8\u96c6\u3057\u307e\u3059 ] Ulbricht\u306e\u4ee5\u524d\u306e\u85ac\u7269\u52d5\u614b\u7814\u7a76 [24] \u3068czok [25] \u30e9\u30c3\u30c8\u3068\u30de\u30a6\u30b9\u3067\u53e3\u982d\u307e\u305f\u306f\u9759\u8108\u5185\u3067100 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HMF\u306e\u500b\u3005\u306e\u7d4c\u53e3\u6295\u4e0e\u91cf\u30920.08\u301c330 mg\/kg\u3067\u7d4c\u53e3\u307e\u305f\u306f\u9759\u8108\u5185\u6295\u4e0e\u3057\u305f\u5834\u5408\u3001\u653e\u5c04\u80fd\u306e1\uff05\u672a\u6e80\u304c\u4f53\u5916\u81d3\u5668\u304a\u3088\u3073\u4fbf\u306b\u6291\u5236\u3055\u308c\u307e\u3057\u305f\u3002\u653e\u5c04\u80fd\u306e85\uff05\u306f\u30018\u6642\u9593\u5f8c\u306b\u6392\u9664\u3055\u308c\u300124\u6642\u9593\u5f8c\u306b\u653e\u5c04\u80fd\u306e95\u301c100\uff05\u304c\u6392\u9664\u3055\u308c\u307e\u3057\u305f\u3002 5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30e1\u30c1\u30eb-2-\u30d5\u30ed\u30b7\u30f3\u9178\uff08HMFA\uff09\u304a\u3088\u3073N-\uff085-\u30d2\u30c9\u30ed\u30ad\u30b7\u30e1\u30c1\u30eb-2-\u30d5\u30ed\u30a4\u30eb\uff09\u30b0\u30ea\u30b7\u30f3\u306f\u3001NMR\u304a\u3088\u3073MS\u306b\u3088\u3063\u3066\u4ee3\u8b1d\u7269\u3068\u3057\u3066\u540c\u5b9a\u3055\u308c\u307e\u3057\u305f\u3002 jellum [27] HMFA\u304a\u3088\u3073Furan 2.5-\u30b8\u30ab\u30eb\u30dc\u30f3\u9178\uff08FDCA\uff09\u3068\u3057\u3066\u306e\u5c3f\u306e\u7d0450\uff05\u304c\u3001\u89aa\u306eHMF\u304cFructosele\u6eb6\u6db2\u3067\u6295\u4e0e\u3055\u308c\u305f\u5f8c\u306b\u6392\u9664\u3055\u308c\u305f\u3053\u3068\u304c\u308f\u304b\u308a\u307e\u3057\u305f\u3002\u5909\u66f4\u3055\u308c\u3066\u3044\u306a\u3044HMF\u3084\u30b0\u30ea\u30b7\u30f3\u30b3\u30f3\u30b8\u30e5\u30b2\u30fc\u30c8\u306f\u5c3f\u4e2d\u306b\u898b\u3064\u304b\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u30b4\u30c3\u30c9\u30d5\u30ea\u30fc [28] 5\u301c500 mg\/kg\u306e\u7528\u91cf\u306e\u30de\u30a6\u30b9\u3068\u30e9\u30c3\u30c8\u306eHMF\u3002\u6295\u4e0e\u3055\u308c\u305f\u7528\u91cf\u306e60\u301c80\uff05\u306f\u3001\u5c3f\u5f8c48\u6642\u9593\u4ee5\u5185\u306b\u9664\u53bb\u3055\u308c\u307e\u3057\u305f\u3002 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Monias\u306b\u3088\u308b\u6700\u8fd1\u306e\u7814\u7a76\u3092\u9664\u3044\u3066\u3001\u30df\u30e5\u30fc\u30bf\u30b2\u30f3\u304a\u3088\u3073\u767a\u304c\u3093\u6027\u3068\u3057\u3066\u8a3c\u660e\/\u6c7a\u5b9a\u3055\u308c\u305f\u5f62\u6210\u304c\u4e0a\u8a18\u306e\u5831\u544a\u306b\u8a18\u8f09\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002 [29] \u4ee3\u8b1d\u7269\u3068\u3057\u3066\u89b3\u5bdf\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002\u8457\u8005\u3089\u306f\u3001SMF\u304cHMF\u51e6\u7406\u30de\u30a6\u30b9\u3067\u5f62\u6210\u3055\u308c\u3066\u3044\u308b\u3053\u3068\u3092\u793a\u3057\u307e\u3057\u305f\u3002 LC-MS\/MS\u304c\u5206\u6790\u306b\u4f7f\u7528\u3055\u308c\u307e\u3057\u305f\u3002\u3057\u304b\u3057\u3001SMF\u306f\u4eba\u9593\u306e\u4ee3\u8b1d\u7269\u3068\u3057\u3066\u306f\u898b\u3064\u304b\u308a\u307e\u305b\u3093\u3067\u3057\u305f\u3002 5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30e1\u30c1\u30eb\u30d5\u30a1\u30fc\u30bb\u306e\u4e00\u822c\u7684\u306a\u30e1\u30ab\u30cb\u30ba\u30e0 [ 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