[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/1859#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/1859","headline":"Algoritmo Smith -Waterman -Wikipedia\u3001LA Enciclopedia free","name":"Algoritmo Smith -Waterman -Wikipedia\u3001LA Enciclopedia free","description":"before-content-x4 \u5f7c \u30b9\u30df\u30b9\u30a6\u30a9\u30fc\u30bf\u30fc\u30de\u30f3\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0 \u3053\u308c\u306f\u3001\u751f\u7269\u5b66\u7684\u914d\u5217\uff08DNA\u3001RNA\u3001\u307e\u305f\u306f\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u306e\u5c40\u6240\u6574\u5217\u3092\u5b9f\u884c\u3059\u308b\u305f\u3081\u306e\u8a8d\u8b58\u3055\u308c\u305f\u6226\u7565\u3067\u3059\u3002\u8a00\u3044\u63db\u3048\u308c\u3070\u3001\u3044\u304f\u3064\u304b\u306e\u30b7\u30fc\u30b1\u30f3\u30b9\u9593\u3067\u540c\u69d8\u306e\u9818\u57df\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002 SW\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u30011981\u5e74\u306bTemple Smith\u3068Michael Waterman\u306b\u3088\u3063\u3066\u63d0\u6848\u3055\u308c\u307e\u3057\u305f\u3002 [ \u521d\u3081 ] \u3053\u308c\u306f\u3001\u52d5\u7684\u30d7\u30ed\u30b0\u30e9\u30df\u30f3\u30b0\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u4f7f\u7528\u306b\u57fa\u3065\u3044\u3066\u3044\u308b\u305f\u3081\u3001\u4f7f\u7528\u3055\u308c\u308b\u7279\u5b9a\u306e\u30b9\u30b3\u30a2\u30b7\u30b9\u30c6\u30e0\uff08\u7f6e\u63db\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306a\u3069\uff09\u306b\u95a2\u3057\u3066\u3001\u5c40\u6240\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u304c\u6700\u9069\u3067\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3059\u308b\u3068\u3044\u3046\u671b\u307e\u3057\u3044\u7279\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u3044\u304f\u3064\u304b\u306e\u30b7\u30fc\u30b1\u30f3\u30b9\u3092\u8abf\u6574\u3059\u308b\u305f\u3081\u306e\u57fa\u672c\u7684\u306a\u4ee3\u66ff\u54c1\u306f\u3001\u30ed\u30fc\u30ab\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u3068\u30b0\u30ed\u30fc\u30d0\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u3067\u3059\u3002 \u30b0\u30ed\u30fc\u30d0\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u306f\u3001\u5404\u30b7\u30fc\u30b1\u30f3\u30b9\u306b\u5404\u30b7\u30f3\u30dc\u30eb\uff08\u307e\u305f\u306f\u6b8b\u57fa\uff09\u3092\u6574\u5217\u3055\u305b\u308b\u3053\u3068\u3092\u76ee\u7684\u3068\u3057\u3066\u3044\u307e\u3059\u3002\u3053\u306e\u6226\u7565\u306f\u3001\u6574\u5217\u3059\u308b\u30b7\u30fc\u30b1\u30f3\u30b9\u304c\u975e\u5e38\u306b\u985e\u4f3c\u3057\u3066\u304a\u308a\u3001\u307b\u307c\u540c\u3058\u30b5\u30a4\u30ba\u3067\u3042\u308b\u5834\u5408\u306b\u7279\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002\u5bfe\u7167\u7684\u306b\u3001\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u3059\u308b\u30b7\u30fc\u30b1\u30f3\u30b9\u306b\u5927\u304d\u306a\u9055\u3044\u304c\u3042\u308b\u5834\u5408\u3001\u30ed\u30fc\u30ab\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u306f\u3088\u308a\u6709\u7528\u3067\u3059\u304c\u3001\u985e\u4f3c\u6027\u306e\u9818\u57df\u304c\u3042\u308b\u3068\u7591\u308f\u308c\u3066\u3044\u307e\u3059\u3002 \u30b7\u30e7\u30fc\u30f3 a = a 1a 2\u3002 \u3002","datePublished":"2019-11-13","dateModified":"2019-11-13","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/wikimedia.org\/api\/rest_v1\/media\/math\/render\/svg\/342e8f1f711da408174a056a2a728a601bdbbf3f","url":"https:\/\/wikimedia.org\/api\/rest_v1\/media\/math\/render\/svg\/342e8f1f711da408174a056a2a728a601bdbbf3f","height":"","width":""},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/1859","wordCount":9577,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4\u5f7c \u30b9\u30df\u30b9\u30a6\u30a9\u30fc\u30bf\u30fc\u30de\u30f3\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0 \u3053\u308c\u306f\u3001\u751f\u7269\u5b66\u7684\u914d\u5217\uff08DNA\u3001RNA\u3001\u307e\u305f\u306f\u30bf\u30f3\u30d1\u30af\u8cea\uff09\u306e\u5c40\u6240\u6574\u5217\u3092\u5b9f\u884c\u3059\u308b\u305f\u3081\u306e\u8a8d\u8b58\u3055\u308c\u305f\u6226\u7565\u3067\u3059\u3002\u8a00\u3044\u63db\u3048\u308c\u3070\u3001\u3044\u304f\u3064\u304b\u306e\u30b7\u30fc\u30b1\u30f3\u30b9\u9593\u3067\u540c\u69d8\u306e\u9818\u57df\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002 SW\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u30011981\u5e74\u306bTemple Smith\u3068Michael Waterman\u306b\u3088\u3063\u3066\u63d0\u6848\u3055\u308c\u307e\u3057\u305f\u3002 [ \u521d\u3081 ] \u3053\u308c\u306f\u3001\u52d5\u7684\u30d7\u30ed\u30b0\u30e9\u30df\u30f3\u30b0\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u4f7f\u7528\u306b\u57fa\u3065\u3044\u3066\u3044\u308b\u305f\u3081\u3001\u4f7f\u7528\u3055\u308c\u308b\u7279\u5b9a\u306e\u30b9\u30b3\u30a2\u30b7\u30b9\u30c6\u30e0\uff08\u7f6e\u63db\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306a\u3069\uff09\u306b\u95a2\u3057\u3066\u3001\u5c40\u6240\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u304c\u6700\u9069\u3067\u3042\u308b\u3053\u3068\u3092\u78ba\u8a8d\u3059\u308b\u3068\u3044\u3046\u671b\u307e\u3057\u3044\u7279\u6027\u304c\u3042\u308a\u307e\u3059\u3002 \u3044\u304f\u3064\u304b\u306e\u30b7\u30fc\u30b1\u30f3\u30b9\u3092\u8abf\u6574\u3059\u308b\u305f\u3081\u306e\u57fa\u672c\u7684\u306a\u4ee3\u66ff\u54c1\u306f\u3001\u30ed\u30fc\u30ab\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u3068\u30b0\u30ed\u30fc\u30d0\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u3067\u3059\u3002 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\u30b7\u30e7\u30fc\u30f3 a = a 1a 2\u3002 \u3002 \u3002 a n{displaystyle a = a_ {1} a_ {2} … a_ {n}} \u3068 b = b 1b 2\u3002 \u3002 \u3002 b m{displaystyle b = b_ {1} b_ {2} … b_ {m}} \u6574\u5217\u3059\u308b2\u3064\u306e\u751f\u7269\u5b66\u7684\u914d\u5217\u3001\u305d\u306e\u9577\u3055\u306f n {displaystyle n} \u3068 m {displaystyle m} \u305d\u308c\u305e\u308c\u3002 2\u3064\u306e\u8981\u7d20\u9593\u306e\u985e\u4f3c\u6027\u30b9\u30b3\u30a2 a {displaystyle a} \u3068 b {displaystyle b} \u306b\u3088\u3063\u3066\u4e0e\u3048\u3089\u308c\u307e\u3059 s \uff08 a \u3001 b \uff09\uff09 {displaystyleS\uff08a\u3001b\uff09} \u3002\u9577\u3055\u306e\u6392\u9664\u3054\u3068\u306b k {displaystyle k} \u30da\u30ca\u30eb\u30c6\u30a3\u304c\u5272\u308a\u5f53\u3066\u3089\u308c\u307e\u3059 \u306e k{displaystylew_ {k}} \u3002 \u985e\u4f3c\u6027\u304c\u975e\u5e38\u306b\u9ad8\u3044\u30bb\u30b0\u30e1\u30f3\u30c8\u3092\u3044\u304f\u3064\u304b\u898b\u3064\u3051\u308b\u306b\u306f\u3001\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u304c\u69cb\u7bc9\u3055\u308c\u3066\u3044\u307e\u3059 h {displaystyle h} \u306e \uff08 n + \u521d\u3081 \uff09\uff09 {displaystyle\uff08n+1\uff09} \u00d7 \uff08 m + \u521d\u3081 \uff09\uff09 {displaystyle\uff08m+1\uff09} \u3001\u5024\u3092\u6301\u3064\u6700\u521d\u306e\u5217\u3068\u6700\u521d\u306e\u884c\u3092\u521d\u671f\u5316\u3059\u308b 0 {displaystyle 0} \u3002 Hk0=H0l=0para0\u2264k\u2264ny0\u2264l\u2264m{displaystyle h_ {k0} = h_ {0l} = 0quad paraquad 0leq kleq nquad yquad 0leq lleq m} \u3002 \u5404\u5024 Hij{displaystyle h_ {ij}} \u3067\u7d42\u308f\u308b2\u3064\u306e\u30bb\u30b0\u30e1\u30f3\u30c8\u9593\u306e\u6700\u5927\u985e\u4f3c\u6027\u3092\u8868\u3057\u307e\u3059 ai{displaystyle a_ {i}} \u3068 bj{displaystyle b_ {j}} \u305d\u308c\u305e\u308c\u3002\u3053\u308c\u3089\u306e\u5024\u306f\u3001\u6b21\u306e\u518d\u767a\u95a2\u4fc2\u304b\u3089\u5f97\u3089\u308c\u307e\u3059\u3002 Hij=max{Hi\u22121,j\u22121+s(ai,bj),maxk\u22651{Hi\u2212k,j\u2212Wk},maxl\u22651{Hi,j\u2212l\u2212Wl},0(1\u2264i\u2264n,1\u2264j\u2264m){displaystyle h_ {ij} = max {begin {cases} h_ {i-1\u3001j-1}+s\uff08a_ {i}\u3001b_ {j}\uff09\u3001\\ max _ {kgeq 1} {h_ {i-k\u3001j} -w_ {k}}} {l}}\u3001\\ 0end {case}} qquad\uff081leq ileq n\u30011leq jleq m\uff09} \u3069\u3053 Hi\u22121,j\u22121+s(ai,bj){displaystyle h_ {i-1\u3001j-1}+s\uff08a_ {i}\u3001b_ {j}\uff09} \u305d\u308c\u306fAlign\u30b9\u30b3\u30a2\u3067\u3059 ai{displaystyle a_ {i}} \u3068 bj{displaystyle b_ {j}} \u3001 Hi\u2212k,j\u2212Wk{displaystyle h_ {i-k\u3001j} -w_ {k}} \u305d\u308c\u306f\u30b9\u30b3\u30a2\u3067\u3059 ai{displaystyle a_ {i}} \u9577\u3055\u306e\u9664\u53bb\u306e\u7d42\u308f\u308a\u3067\u3059 k{displaystyle k} \u3001 Hi,j\u2212l\u2212Wl{displaystyle h_ {i\u3001j -l} -w_ {l}} \u305d\u308c\u306f\u30b9\u30b3\u30a2\u3067\u3059 bj{displaystyle b_ {j}} \u9577\u3055\u306e\u9664\u53bb\u306e\u7d42\u308f\u308a\u3067\u3059 l{displaystyle l} \u3001 0{displaystyle 0} \u9593\u306b\u985e\u4f3c\u6027\u304c\u306a\u3044\u3053\u3068\u3092\u793a\u3057\u307e\u3059 ai{displaystyle a_ {i}} \u3068 bj{displaystyle b_ {j}} \u3001\u3053\u306e\u5024\u306f\u3001\u8ca0\u306e\u5024\u3092\u56de\u907f\u3059\u308b\u305f\u3081\u306b\u8ffd\u52a0\u3055\u308c\u307e\u3059\u3002 \u6700\u5927\u306e\u985e\u4f3c\u6027\u3067\u30bb\u30b0\u30e1\u30f3\u30c8\u306e\u30da\u30a2\u3092\u56de\u5fa9\u3059\u308b\u305f\u3081\u306b\u3001\u306e\u9006\u30c8\u30e9\u30c3\u30ad\u30f3\u30b0\u304c\u6700\u5927\u8981\u7d20\u304b\u3089\u5b9f\u884c\u3055\u308c\u307e\u3059 h {displaystyle h} \u5024\u304c\u7b49\u3057\u3044\u8981\u7d20\u3067\u7d42\u308f\u308b\u307e\u3067 0 {displaystyle 0} \u3001\u3053\u308c\u304c\u6700\u9069\u306a\u30ed\u30fc\u30ab\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u306e\u59cb\u307e\u308a\u3067\u3059\u3002 Table of Contents\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u8907\u96d1\u3055 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u4f8b [ \u7de8\u96c6\u3057\u307e\u3059 ] \u30ae\u30e3\u30c3\u30d7\u306b\u3088\u308b\u30da\u30ca\u30eb\u30c6\u30a3 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u7dda\u5f62\u30da\u30ca\u30eb\u30c6\u30a3 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u95a2\u9023\u7a74 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u51f8\u72b6\u306e\u304f\u307c\u307f [ \u7de8\u96c6\u3057\u307e\u3059 ] \u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u53c2\u7167 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u5916\u90e8\u30ea\u30f3\u30af [ \u7de8\u96c6\u3057\u307e\u3059 ] \u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u8907\u96d1\u3055 [ \u7de8\u96c6\u3057\u307e\u3059 ] Smith-Waterman\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306b\u306f\u3001\u4e00\u6642\u7684\u306a\u8907\u96d1\u3055\u304c\u3042\u308a\u307e\u3059 o \uff08 n m 2\uff09\uff09 {displaystyle o\uff08nm^{2}\uff09}        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u306e\u7a7a\u9593\u7684\u306a\u8907\u96d1\u3055 o \uff08 n m \uff09\uff09 {displaystyle o\uff08nm\uff09} \u3002\u3053\u308c\u306f\u3001\u30d6\u30eb\u30fc\u30c8\u30d5\u30a9\u30fc\u30b9\u30a2\u30d7\u30ed\u30fc\u30c1\u306b\u95a2\u3059\u308b\u8a08\u7b97\u30b3\u30b9\u30c8\u306e\u5927\u5e45\u306a\u6e1b\u5c11\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002 o \uff08 n 3m 3\uff09\uff09 {displaystyle o\uff08n^{3} m^{3}\uff09} \u305d\u308c\u3089\u304c\u5b58\u5728\u3059\u308b\u304b\u3089\u3067\u3059 (n2){displaystyle {binu {n} {2}}}} \u3068        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4(m2){displaystyle {binom {m} {2}}} \u306e\u30b5\u30d6\u30b1\u30f3\u30b9 a {displaystyle a} \u3068 b {displaystyle b} \u305d\u308c\u305e\u308c\u3002\u305f\u3060\u3057\u3001\u305d\u306e\u8907\u96d1\u3055\u306f\u3001Needleman-Wunsch\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u8907\u96d1\u3055\u3068\u6bd4\u8f03\u3057\u3066\u4e0d\u5229\u306a\u70b9\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002 [ 2 ] \u305d\u308c\u306f\u7dda\u5f62\u306e\u8907\u96d1\u3055\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u7279\u306b\u306e\u4fa1\u5024\u306e\u5834\u5408 m {displaystyle m} \u975e\u5e38\u306b\u5927\u304d\u3044\u3067\u3059\u3002\u305d\u308c\u304c\u3001\u7dda\u5f62\u5b9f\u884c\u6642\u9593\u304c\u3042\u308b\u4ee3\u66ff\u6848\u304c\u958b\u767a\u3055\u308c\u305f\u7406\u7531\u3067\u3059 [ 3 ] \u200b [ 4 ] \u305d\u306e\u4ed6\u306f\u3001\u306b\u95a2\u3057\u3066\u7dda\u5f62\u7a7a\u9593\u7684\u306a\u8907\u96d1\u3055\u3092\u5099\u3048\u3066\u3044\u307e\u3059        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4n {displaystyle n} \u3002 [ 5 ] \u200b \u4f8b [ \u7de8\u96c6\u3057\u307e\u3059 ] \u30b7\u30e7\u30fc\u30f3 a {displaystyle a} \uff1aaaggct y b {displaystyle b} \uff1aAACCCG\u985e\u4f3c\u6027\u30b9\u30b3\u30a2\u306b\u5408\u308f\u305b\u30662\u3064\u306e\u30b7\u30fc\u30b1\u30f3\u30b9\u306f\u3001\u6b21\u306e\u95a2\u4fc2\u306b\u3088\u3063\u3066\u4e0e\u3048\u3089\u308c\u307e\u3059\u3002 s \uff08 a i\u3001 b j\uff09\uff09 = {+1,ai=bj\u22121,ai\u2260bj{displaystyle s\uff08a_ {i}\u3001b_ {j}\uff09= {begin {cases}+1\u3001quad a_ {i} = b_ {j} \\ -1\u3001quad a_ {i} neq b_ {j} end {cases}}}}} \u3002 \u30b9\u30b3\u30a2\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306f\u521d\u671f\u5316\u3055\u308c\u307e\u3059 0 {displaystyle 0} \u6700\u521d\u306e\u5217\u3068\u6700\u524d\u5217\u306e\u3059\u3079\u3066\u306e\u8981\u7d20\u306b\u3064\u3044\u3066\u3002\u6b21\u306b\u3001\u3059\u3079\u3066\u306e\u53e5\u8aad\u70b9\u304c\u9593\u306b\u8a08\u7b97\u3055\u308c\u307e\u3059 a i{displaystyle a_ {i}} \u3068 b j{displaystyle b_ {j}} \u3001 \u304b\u3089\u59cb\u307e\u308b a 1{displaystyle a_ {1}} \u3068 b 1{displaystyle b_ {1}} \u3001\u6b21\u306e\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306b\u9ec4\u8272\u3067\u793a\u3055\u308c\u307e\u3059\u3002   a a c c c g  0 0 0 0 0 0 0 a 0 \u521d\u3081  a 0  g 0  g 0  c 0  t 0  \u3059\u3079\u3066\u306e\u5024\u304c\u8a08\u7b97\u3055\u308c\u308b\u3068\u3001\u7dd1\u3067\u793a\u3055\u308c\u308b\u6700\u5927\u30b9\u30b3\u30a2\u3067\u8981\u7d20\u304c\u6c42\u3081\u3089\u308c\u307e\u3059\u3002   a a c c c g  0 0 0 0 0 0 0 a 0 \u521d\u3081 \u521d\u3081 0 0 0 0 a 0 \u521d\u3081 2 \u521d\u3081 0 0 0 g 0 0 \u521d\u3081 \u521d\u3081 0 0 \u521d\u3081 g 0 0 0 0 0 0 \u521d\u3081 c 0 0 0 \u521d\u3081 \u521d\u3081 \u521d\u3081 0 t 0 0 0 0 0 0 0 \u6700\u5f8c\u306b\u3001\u306e\u6700\u9069\u306a\u30ed\u30fc\u30ab\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u3092\u56de\u5fa9\u3059\u308b\u305f\u3081 a {displaystyle a} \u3068 b {displaystyle b} \u305d\u306e\u8981\u7d20\u304b\u3089\u3001\u5024\u306e\u3042\u308b\u8981\u7d20\u306b\u5230\u9054\u3059\u308b\u307e\u3067\u8ffd\u8de1\u304c\u5b9f\u884c\u3055\u308c\u307e\u3059 0 {displaystyle 0} \u3002   a a c c c g  0 0 0 0 0 0 0 a 0 \u521d\u3081 \u521d\u3081 0 0 0 0 a 0 \u521d\u3081 2 \u521d\u3081 0 0 0 g 0 0 \u521d\u3081 \u521d\u3081 0 0 \u521d\u3081 g 0 0 0 0 0 0 \u521d\u3081 c 0 0 0 \u521d\u3081 \u521d\u3081 \u521d\u3081 0 t 0 0 0 0 0 0 0 \u3053\u306e\u4f8b\u304b\u3089\u751f\u3058\u308b\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u306f\u3001\u5404\u30b7\u30fc\u30b1\u30f3\u30b9\u306e\u6700\u521d\u306e2\u3064\u306e\u8981\u7d20\u306e\u307f\u3092\u6574\u5217\u3059\u308b\u3053\u3068\u3067\u3059\u3002 \u52dd\u8ca0\u3092\u53d7\u3051\u3066\u7acb\u3064||\u52dd\u8ca0\u3092\u53d7\u3051\u3066\u7acb\u3064 \u30ae\u30e3\u30c3\u30d7\u306b\u3088\u308b\u30da\u30ca\u30eb\u30c6\u30a3 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u7dda\u5f62\u30da\u30ca\u30eb\u30c6\u30a3 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u7a74\u306e\u30da\u30ca\u30eb\u30c6\u30a3\u306f\u3001\u30a4\u30f3\u30c7\u30eb\u306e\u30b9\u30b3\u30a2\u3001\u3064\u307e\u308a\u633f\u5165\u307e\u305f\u306f\u6392\u9664\u3092\u6c7a\u5b9a\u3059\u308b\u306e\u306b\u5f79\u7acb\u3061\u307e\u3059\u3002 Smith-Waterman\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f\u3001\u30da\u30ca\u30eb\u30c6\u30a3\u304c\u3042\u308b\u30db\u30fc\u30eb\u306e\u9577\u3055\u3092\u5ef6\u9577\u3059\u308b\u305f\u3081\u306b\u7dda\u5f62\u30da\u30ca\u30eb\u30c6\u30a3\u3092\u4f7f\u7528\u3057\u307e\u3059\u3002 \u306e k{displaystylew_ {k}} \u9577\u3055\u306e\u307f\u306b\u4f9d\u5b58\u3057\u307e\u3059 k {displaystyle k} \u7a74\u3068\u30b3\u30b9\u30c8\u306e \u306e 1{distrastaStyle w_ {1}} \u5358\u4e00\u306e\u30b9\u30da\u30fc\u30b9\u30db\u30fc\u30eb\u306e\uff1a \u306e k= k \u306e 1{displaystyle w_ {k} = kw_ {1}} \u3002 \u95a2\u9023\u7a74 [ \u7de8\u96c6\u3057\u307e\u3059 ] GOTOH\u306f\u3001\u30da\u30ca\u30eb\u30c6\u30a3\u306e\u5909\u66f4\u306b\u69cb\u6210\u3055\u308c\u308b\u95a2\u9023\u30db\u30fc\u30eb\u306e\u30e2\u30c7\u30eb\u3092\u63d0\u6848\u3057\u307e\u3057\u305f \u306e k{displaystylew_ {k}} \u3053\u308c\u304c2\u3064\u306e\u30d1\u30e9\u30e1\u30fc\u30bf\u30fc\u306e\u95a2\u6570\u3067\u3042\u308b\u3088\u3046\u306b\uff1a \u306e k= \u306e k + \u306e {displaystyle w_ {k} = uk+v} \u3001 \u3069\u3053 \u306e {displaystyleu} \u7a74\u3092\u5e83\u3052\u308b\u3053\u3068\u306f\u30da\u30ca\u30eb\u30c6\u30a3\u3067\u3059\u3001 \u306e {displaystyle v} \u305d\u308c\u306f\u7a74\u3092\u958b\u59cb\u3059\u308b\u305f\u3081\u306e\u30da\u30ca\u30eb\u30c6\u30a3\u3067\u3059 k {displaystyle k} \u7a74\u306e\u9577\u3055\u3067\u3059\u3002\u3053\u306e\u30b9\u30ad\u30fc\u30e0\u306f\u3001\u5834\u5408\u306b\u7dda\u5f62\u30da\u30ca\u30eb\u30c6\u30a3\u306b\u524a\u6e1b\u3055\u308c\u307e\u3059 \u306e = 0 {displaystyleu = 0} \u3002\u3053\u306e\u30e2\u30c7\u30eb\u306f2\u3064\u306e\u5229\u70b9\u3092\u63d0\u4f9b\u3057\u307e\u3059\u3002\u64cd\u4f5c\u306e\u6570\u3092\u6e1b\u3089\u3059 o \uff08 m n \uff09\uff09 {displaystyle o\uff08mn\uff09} \u7a74\u3092\u5ef6\u9577\u3059\u308b\u3088\u308a\u3082\u3001\u7a74\u3092\u958b\u59cb\u3059\u308b\u305f\u3081\u306b\u9ad8\u3044\u30b3\u30b9\u30c8\u3092\u5272\u308a\u5f53\u3066\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u6700\u5f8c\u306e\u7279\u6027\u306f\u3001\u5358\u7d14\u306a\u5909\u7570\u304c\u30b7\u30fc\u30b1\u30f3\u30b9\u306e\u30bb\u30b0\u30e1\u30f3\u30c8\u306b\u3044\u304f\u3064\u304b\u306e\u5909\u5316\u3092\u5f15\u304d\u8d77\u3053\u3059\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3001\u91cd\u8981\u306a\u751f\u7269\u5b66\u7684\u610f\u5473\u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u3057\u305f\u304c\u3063\u3066\u3001\u7a74\u306e\u4f5c\u6210\u306f\u901a\u5e38\u3001\u305d\u306e\u9577\u3055\u3088\u308a\u3082\u5927\u304d\u306a\u5f71\u97ff\u3092\u53ca\u307c\u3057\u307e\u3059\u3002 GOTOH\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306e\u8a08\u7b97\u30b3\u30b9\u30c8\u306e\u6e1b\u5c11\u306f\u3001\u6700\u9069\u306a\u30ed\u30fc\u30ab\u30eb\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u306e1\u3064\u3060\u3051\u3092\u898b\u3064\u3051\u3088\u3046\u3068\u3057\u3001\u6700\u9069\u306a\u30a2\u30e9\u30a4\u30e1\u30f3\u30c8\u304c\u5e38\u306b\u898b\u3064\u3051\u305f\u3082\u306e\u3092\u3059\u3079\u3066\u898b\u3064\u3051\u3088\u3046\u3068\u3059\u308b\u30b9\u30df\u30b9\u30a6\u30a9\u30fc\u30bf\u30fc\u30de\u30f3\u3068\u306f\u7570\u306a\u308a\u3001\u4f55\u3082\u898b\u3064\u3051\u308b\u3053\u3068\u3092\u4fdd\u8a3c\u3057\u306a\u3044\u3068\u3044\u3046\u4e8b\u5b9f\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002 GOTOH\u30a2\u30eb\u30b4\u30ea\u30ba\u30e0\u306f3\u3064\u306e\u884c\u5217\u3092\u4f7f\u7528\u3057\u307e\u3059 n \u00d7 m {displaystyle ntimes m} \uff1a \u3053\u308c\u3089\u306e\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306b\u306f\u3001\u6b21\u306e\u521d\u671f\u5316\u304c\u3042\u308a\u307e\u3059\u3002 D0,j= Wj{displaystyle d_ {0\u3001j} = w_ {j}} \u3001 Di,0= Wi{displaystyle d_ {i\u30010} = w_ {i}} \u3001 P0,j= \u221e {displaystyle p_ {0\u3001j} = infty} \u3001 Qj,0= \u221e {displaystyle q_ {j\u30010} = infty} \u3053\u308c\u3089\u306e\u30de\u30c8\u30ea\u30c3\u30af\u30b9\u306e\u5024\u306f\u3001\u6b21\u306e\u518d\u767a\u95a2\u4fc2\u304b\u3089\u5f97\u3089\u308c\u307e\u3059\u3002 Di,j= \u5206 {Di\u22121,j\u22121+s(ai,bj),Pi,j,Qi,j{displaystyle d_ {i\u3001j} = min {begin {cases} d_ {i-1\u3001j-1}+s\uff08a_ {i}\u3001b_ {j}\uff09\u3001\\ p_ {i\u3001j}\u3001\\ q_ {i\u3001j} \\ end {case}}}}}}} Pi,j= \u5206 {Di\u22121,j+W1,Pi\u22121,j+u{displaystyle P_ {i\u3001j} = min {begin {cases} d_ {i-1\u3001j}+w_ {1}\u3001\\ p_ {i-1\u3001j}+u \\ end {cases}}}}} Qi,j= \u5206 {Di,j\u22121+W1,Qi,j\u22121+u{displaystyle q_ {i\u3001j} = min {begin {cases} d_ {i\u3001j-1}+w_ {1}\u3001\\ q_ {i\u3001j-1}+u \\ end {cases}}}}} \u51f8\u72b6\u306e\u304f\u307c\u307f [ \u7de8\u96c6\u3057\u307e\u3059 ] \u30a6\u30a9\u30fc\u30bf\u30fc\u30de\u30f3 [ 6 ] \u5f7c\u306f\u3001\u3055\u3089\u306b\u67d4\u8edf\u306a\u30da\u30ca\u30eb\u30c6\u30a3\u30b7\u30b9\u30c6\u30e0\u3092\u63d0\u6848\u3057\u307e\u3057\u305f\u3002\u7a74\u306e\u958b\u59cb\u3068\u5ef6\u9577\u306e\u30b3\u30b9\u30c8\u304c\u4e00\u5b9a\u3067\u3042\u308b\u95a2\u9023\u30db\u30fc\u30eb\u30e2\u30c7\u30eb\u3068\u306f\u7570\u306a\u308a\u3001 \u306e {displaystyleu} \u3068 \u306e {displaystyle v} \u305d\u308c\u305e\u308c\u3001\u51f8\u7a74\u306e\u30da\u30ca\u30eb\u30c6\u30a3\u3067\u306f\u3001\u305d\u306e\u9577\u3055\u304c\u5897\u52a0\u3059\u308b\u306b\u3064\u308c\u3066\u7a74\u3092\u5ef6\u9577\u3059\u308b\u30b3\u30b9\u30c8\u304c\u6e1b\u5c11\u3057\u307e\u3059\u3002 \u306e k+1 –  \u306e k\u2264 \u306e k –  \u306e k\u22121{displaystyle w_ {k+1} -w_ {k} leq w_ {k} -w_ {k-1}} \u3002 \u53c2\u7167\u3057\u3066\u304f\u3060\u3055\u3044 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u53c2\u7167 [ \u7de8\u96c6\u3057\u307e\u3059 ] \u5916\u90e8\u30ea\u30f3\u30af [ \u7de8\u96c6\u3057\u307e\u3059 ]           (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/1859#breadcrumbitem","name":"Algoritmo Smith -Waterman -Wikipedia\u3001LA Enciclopedia free"}}]}]