[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19149#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19149","headline":"Hydroxylysin  – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","name":"Hydroxylysin  – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","description":"before-content-x4 \u69cb\u9020\u5f0f \u5168\u822c\u7684 \u540d\u524d \u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3 \u4ed6\u306e\u540d\u524d 5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3 2.6-\u30b8\u30a2\u30df\u30ce5\u30d2\u30c9\u30ed\u30ad\u30b7\u30ab\u30d7\u30ed\u30f3\u9178 \uff082 s \u30015 r \uff09-2.6-\u30b8\u30a2\u30df\u30ce5\u30d2\u30c9\u30ed\u30ad\u30b7\u30d8\u30ad\u30b5\u30f3\u9178 \u30de\u30c3\u30b7\u30e5\u30d5\u30a9\u30fc\u30df\u30e5\u30e9 c 6 h 14 n 2","datePublished":"2020-08-06","dateModified":"2020-08-06","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/c\/c9\/5-Hydroxy-L-lysin.svg\/250px-5-Hydroxy-L-lysin.svg.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/c\/c9\/5-Hydroxy-L-lysin.svg\/250px-5-Hydroxy-L-lysin.svg.png","height":"106","width":"250"},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19149","wordCount":643,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4\u69cb\u9020\u5f0f  \u5168\u822c\u7684 \u540d\u524d \u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3 \u4ed6\u306e\u540d\u524d 5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3 2.6-\u30b8\u30a2\u30df\u30ce5\u30d2\u30c9\u30ed\u30ad\u30b7\u30ab\u30d7\u30ed\u30f3\u9178 \uff082 s \u30015 r \uff09-2.6-\u30b8\u30a2\u30df\u30ce5\u30d2\u30c9\u30ed\u30ad\u30b7\u30d8\u30ad\u30b5\u30f3\u9178 \u30de\u30c3\u30b7\u30e5\u30d5\u30a9\u30fc\u30df\u30e5\u30e9 c 6 h 14 n 2 o 3 \u7c21\u5358\u306a\u8aac\u660e \u30d9\u30fc\u30b8\u30e5\u30d1\u30eb\u30d0\u30fc\uff08\u5869\u9178\u5869\uff09 [\u521d\u3081] \u5916\u90e8\u8b58\u5225\u5b50\/\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9  \u7279\u6027 \u30e2\u30eb\u8cea\u91cf 162,187 g\u30fbmol -1 \u7dcf\u72b6\u614b        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u796d\u308a \u878d\u70b9 225\u2013230\u00b0C\uff08\u5869\u9178\u5869\uff09 [\u521d\u3081] \u5b89\u5168\u306b\u3064\u3044\u3066\u306e\u6848\u5185  \u53ef\u80fd\u306a\u9650\u308a\u4e00\u822c\u7684\u306b\u3001SI\u30e6\u30cb\u30c3\u30c8\u304c\u4f7f\u7528\u3055\u308c\u307e\u3059\u3002\u7279\u306b\u660e\u8a18\u3057\u306a\u3044\u9650\u308a\u3001\u63d0\u4f9b\u3055\u308c\u305f\u30c7\u30fc\u30bf\u306f\u6a19\u6e96\u6761\u4ef6\u306b\u9069\u7528\u3055\u308c\u307e\u3059\u3002 \u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3 \uff08\u3088\u308a\u6b63\u78ba\u306a 5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30fc –  l -laysin \u3001abk\u3002 \u9060\u5420\u3048 \uff091921\u5e74\u306b\u30c9\u30ca\u30eb\u30c9\u30fb\u30f4\u30a1\u30f3\u30fb\u30b9\u30ea\u30b1\u306b\u3088\u3063\u3066\u767a\u898b\u3055\u308c\u305f\u30bf\u30f3\u30d1\u30af\u8cea\u539f\u6027\u304c\u975e\u6a19\u6e96\u7684\u306a\u30a2\u30df\u30ce\u9178\u3067\u3059\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u767a\u751f\u3057\u3066\u3044\u307e\u3059\u304c\u3001\u3053\u306e\u30a2\u30df\u30ce\u9178\u306f\u7ffb\u8a33\u4e2d\u306b\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u306b\u76f4\u63a5\u53d6\u308a\u4ed8\u3051\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u306e\u9178\u5316\u306f\u3001\u9175\u7d20\u30ea\u30b7\u30eb\u30d2\u30c9\u30ed\u30ad\u30b7\u30e9\u30fc\u30bc\uff08\u7ffb\u8a33\u5f8c\u4fee\u98fe\uff09\u306b\u3088\u3063\u3066\u884c\u3046\u3053\u3068\u304c\u3067\u304d\u308b\u306e\u306f\u3001\u30ea\u30b8\u30f3\u3092\u8a2d\u7f6e\u3057\u305f\u5f8c\u306b\u306a\u3063\u3066\u521d\u3081\u3066\u3067\u3059\u3002 5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\uff08\u52d5\u7269\u3068\u4eba\u9593\u306e\u307f\uff09\u304a\u3088\u3073\u30aa\u30dc\u30cd\u30a8\u30c1\u30f3\u306a\u3069\u306e\u4ed6\u306e\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u3067\u767a\u751f\u3057\u307e\u3059\u3002 \u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b8\u30f3\u306f\u3001in\u306a\u3069\u306e\u3088\u3046\u306a\u7d30\u83cc\u3067\u3082\u8a3c\u660e\u3055\u308c\u3066\u3044\u307e\u3059 \u9ec4\u8272\u30d6\u30c9\u30a6\u7403\u83cc \u3002 [2] \u30b3\u30e9\u30fc\u30b2\u30f3\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u5185\u3067\u306f\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u5316\u30ea\u30b8\u30f3\u306e\u5206\u5e03\u30d1\u30bf\u30fc\u30f3\u306f\u3001\u525b\u6027\u3067\u3082\u5b8c\u5168\u306b\u67d4\u8edf\u3067\u3082\u3042\u308a\u307e\u305b\u3093\u3002 H.\u7279\u5b9a\u306e\u4f4d\u7f6e\u3067\u306f\u3001\u5e38\u306b\uff08\u7279\u5b9a\u306e\u7d50\u5408\u7d44\u7e54\u75be\u60a3\u3092\u9664\u304f\uff09\u5e38\u306b\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u5316\u304c\u898b\u3064\u304b\u308a\u307e\u305b\u3093\u3002\u30b3\u30e9\u30fc\u30b2\u30f3\u30c8\u30ea\u30d7\u30eb\u30d8\u30ea\u30c3\u30af\u30b9\u5185\u3067\u306f\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u5316\u30ea\u30b8\u30f3\u306f\u3001Gly-X-Y\u30b7\u30fc\u30b1\u30f3\u30b9\u306eY\u4f4d\u7f6e\u3001\u3064\u307e\u308aGly-X-Hyl\uff08\u30c8\u30ea\u30d7\u30eb\u30d8\u30ea\u30c3\u30af\u30b9\u30b7\u30fc\u30b1\u30f3\u30b9\u3092\u8aac\u660e\u3059\u308b\u305f\u3081\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u3092\u53c2\u7167\uff09\u3067\u306e\u307f\u767a\u751f\u3057\u307e\u3059\u3002\u7565\u3057\u3066\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u306e\u975e\u4e09\u6975\u6027\u9818\u57df\u5185\u3067\u306f\u3001\u4ed6\u306e\u5834\u6240\uff08X-Hyl-Ala\u307e\u305f\u306fX-Hyl-Ser\u306a\u3069\uff09\u306b\u3082\u898b\u3089\u308c\u307e\u3059\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u30ea\u30b8\u30f3\u306e\u3088\u3046\u306b\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30fc\u30b7\u30f3\u306b\u306f\u30b5\u30a4\u30c9\u30c1\u30a7\u30fc\u30f3\u306b\u904a\u96e2\u30a2\u30df\u30ce\u57fa\u304c\u3042\u308a\u307e\u3059\u3002\u30a2\u30eb\u30ae\u30cb\u30f3\u3068\u30d2\u30b9\u30c1\u30b8\u30f3\u3068\u4e26\u3093\u3067\u3001\u5869\u57fa\u6027\u30a2\u30df\u30ce\u9178\u307e\u305f\u306f\u30d8\u30af\u30bd\u30f3\u5869\u57fa\u306e\u30b0\u30eb\u30fc\u30d7\u306b\u5c5e\u3057\u307e\u3059\u3002\u3053\u308c\u3089\u306b\u306f\u3001\u30a2\u30eb\u30ab\u30ea\u6027\u3092\u53cd\u5fdc\u3055\u305b\u308b\u57fa\u672c\u7684\u306a\u30b0\u30eb\u30fc\u30d7\u304c\u3042\u308a\u307e\u3059\u3002\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u306e\u96fb\u8377\u306fpH\u4f9d\u5b58\u6027\u3067\u3059\uff08PK\u5024\uff1a\u224810\uff09\u3002 5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u306f\u3001\u3044\u304f\u3064\u304b\u306e\u30b0\u30ea\u30b3\u30b7\u30eb\u5316\u306e\u305f\u3081\u306e\u6700\u521d\u306e\u7cd6\u6b8b\u57fa\u306e\u51fa\u767a\u70b9\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002\u4e00\u65b9\u3067\u306f\u3001\u30b3\u30e9\u30fc\u30b2\u30f3\u3067\u3053\u306e\u6a5f\u80fd\u3092\u679c\u305f\u3057\u307e\u3059\u3002\u4ed6\u306e\u5834\u6240\u3067\u306f\u3001\u500b\u3005\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u5b50\u9593\u3068\u30b3\u30e9\u30fc\u30b2\u30f3\u30d5\u30a3\u30d6\u30ea\u30eb\u5168\u4f53\u306e\u9593\u306e\u5171\u6709\u7d50\u5408\u306e\u4ea4\u5dee\u306e\u51fa\u767a\u70b9\u3068\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002 \u30b3\u30e9\u30fc\u30b2\u30f3\u5206\u5b50\u5185\u306e\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u306e\u6b20\u4e4f\u306f\u3001\u7d50\u5408\u7d44\u7e54\u306e\u8870\u5f31\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u901a\u5e38\u306f\u4e0d\u6d3b\u6027\u306a\u30ea\u30b7\u30eb\u30d2\u30c9\u30ed\u30ad\u30b7\u30e9\u30fc\u30bc\u306b\u3088\u308b\u3082\u306e\u3067\u3059\u3002\u3053\u306e\u7406\u7531\u306f\u3001\u907a\u4f1d\u7684\u7570\u5e38\uff08Ehlers-Danlos\u75c7\u5019\u7fa4VI\uff09\u307e\u305f\u306f\u4e2d\u6bd2\uff08\u305f\u3068\u3048\u3070\u3001\u7279\u5b9a\u306e\u963b\u5bb3\u5264Bapn =\u03b2-\u30a2\u30df\u30ce\u30d7\u30ed\u30d4\u30aa\u30cb\u30c8\u30ea\u30eb\u3001\u30e9\u30b7\u30ba\u30e0\u306e\u4e2d\u6bd2\u306b\u4f34\u3046\uff09\u3067\u3042\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u81f4\u6b7b\u306f\u5b8c\u5168\u306b\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u6b20\u4e4f\u75c7\u3067\u3042\u308a\u3001\u54fa\u4e73\u985e\u3067\u306f\u30e9\u30a4\u30d6\u30e9\u30a4\u30d6\u3055\u3048\u3067\u304d\u306a\u3044\u3067\u3057\u3087\u3046\u3002 \u5c11\u306a\u304f\u3068\u3082\u30dd\u30ea\u30da\u30d7\u30c1\u30c9\u3078\u306e\u76f4\u63a5\u7684\u306a\u8a2d\u7f6e\u306f\u7ffb\u8a33\u4e2d\u306b\u751f\u7406\u5b66\u7684\u306b\u4e0d\u53ef\u80fd\u3067\u3042\u308b\u305f\u3081\u3001\u30bf\u30f3\u30d1\u30af\u8cea\u5185\u306e\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u306e\u4e0d\u8db3\u306f\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u3092\u5438\u53ce\u3059\u308b\u3053\u3068\u3067\u88dc\u511f\u3059\u308b\u3053\u3068\u306f\u3067\u304d\u307e\u305b\u3093\u3002\u305f\u3060\u3057\u3001\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u306f\u8cb4\u91cd\u306a\u6804\u990a\u88dc\u52a9\u98df\u54c1\u3068\u3057\u3066\u63d0\u4f9b\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305f\u3060\u3057\u3001\u7279\u5225\u306a\u5229\u70b9\u306f\u7591\u308f\u3057\u3044\u3067\u3059\u3002 \u6cbb\u7642\u76ee\u7684\u306e\u305f\u3081\u306b\u963b\u5bb3\u5264Bapn\u306b\u3088\u308b\u30ea\u30b8\u30f3\u306e\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u3078\u306e\u9178\u5316\u306e\u4e88\u9632\u304c\u8003\u616e\u3055\u308c\u307e\u3059\u3002 [3] \u5c3f\u4e2d\u306e\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u691c\u51fa\u306f\u3001\u9aa8\u306e\u30b3\u30e9\u30fc\u30b2\u30f3\u4ee3\u8b1d\u3092\u5b9a\u91cf\u5316\u3059\u308b\u305f\u3081\u306b\u63a1\u7528\u3055\u308c\u3066\u3044\u307e\u3059\u3002 [4] \u2191 a b c d  \u30c7\u30fc\u30bf\u30b7\u30fc\u30c8 DL-5-\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b8\u30f3\u5869\u9178\u5869 2016\u5e7410\u670820\u65e5\u306b\u30a2\u30af\u30bb\u30b9\u3057\u305fSigma-Aldrich\u3067\uff08 PDF \uff09\u3002  \u2191  W. Grady Smith\u3001Daniel P. Gilboe\u3001\u304a\u3088\u3073L. M. Henderson\uff1a \u9ec4\u8272\u30d6\u30c9\u30a6\u7403\u83cc\u306b\u7d30\u80de\u58c1\u3068\u7d30\u80de\u58c1\u524d\u99c6\u4f53\u306b\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b8\u30f3\u3092\u53d6\u308a\u5165\u308c\u308b \u3001In\uff1aJ\u3002Bacteriol\u3002 1965\u30011\u300189\u3001S\u3002136\u2013140; PMC 315560 \uff08\u7121\u6599\u306e\u5168\u6587\uff09\u3002  \u2191  \u7279\u8a31 US4444787 \uff1a \u30b3\u30e9\u30fc\u30b2\u30f3\u67b6\u6a4b\u963b\u5bb3\u5264\u306e\u773c\u79d1\u5c40\u6240\u4f7f\u7528\u3002 \u516c\u958b\u3055\u308c\u3066\u3044\u307e\u3059 24. 1984\u5e744\u6708 \u3001Erfinder\uff1aLouise C. Moorhead\u3002 \u200c  \u2191  K. Yoshihara et al.: \u9aa8\u7c97\u9b06\u75c7\u60a3\u8005\u306b\u304a\u3051\u308b\u30d2\u30c9\u30ed\u30ad\u30b7\u30ea\u30b7\u30f3\u30b0\u30ea\u30b3\u30b7\u30c9\u306e\u5c3f\u6392\u6cc4\u30ec\u30d9\u30eb \u3001 \u306e\uff1a Biol Pharm Bull \u3002 1994\u30016\u300117\u3001S\u3002836\u2013839; PMID 7951149 \u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19149#breadcrumbitem","name":"Hydroxylysin  – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2"}}]}]