[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19578#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19578","headline":"Netropsin -Wikipedia","name":"Netropsin -Wikipedia","description":"before-content-x4 \u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3 \u306f\u3001DNA\u4e8c\u91cd\u3089\u305b\u3093\u306e\u5c0f\u3055\u306a\u6e9d\u306b\u7d50\u5408\u3059\u308b\u30dd\u30ea\u30a2\u30df\u30c9\u6297\u751f\u7269\u8cea\u3067\u3059\u3002 [2] \u30b0\u30e9\u30e0\u967d\u6027\u304a\u3088\u3073\u30b0\u30e9\u30e0\u9670\u6027\u306e\u7d30\u83cc\u306b\u5bfe\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002 [3] DNA\u306b\u7d50\u5408\u3057\u305f\u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u3002 PDB 101d\u304b\u3089\u3002 after-content-x4 Netropsin\u306f1951\u5e74\u306bA. C. Finlay\u306b\u3088\u3063\u3066\u6700\u521d\u306b\u8aac\u660e\u3055\u308c\u307e\u3057\u305f\u3002 Streptomyces Netropsis \u5b64\u7acb\u3057\u3066\u3044\u305f\u3002 [4] \u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u306f\u3001\u30d4\u30ed\u30fc\u30eb – \u30a2\u30df\u30b8\u30f3\u6297\u751f\u7269\u8cea\u30af\u30e9\u30b9\u306b\u5c5e\u3057\u3001\u9060\u4f4d\u6a21\u69d8\u3068\u30ec\u30ad\u30b7\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u306e\u985e\u4f3c\u4f53\u3067\u3059\u3002\u4e8c\u672c\u9396DNA\u3068\u30c6\u30c8\u30e9\u30c7\u30f3[TGGGT]\u306e\u30ea\u30c3\u30c1\u306aDNA\u914d\u5217\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3092\u597d\u3080","datePublished":"2020-10-22","dateModified":"2020-10-22","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/84\/Netropsin_DNA_bound.gif\/110px-Netropsin_DNA_bound.gif","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/84\/Netropsin_DNA_bound.gif\/110px-Netropsin_DNA_bound.gif","height":"207","width":"110"},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19578","wordCount":1195,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4\u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3 \u306f\u3001DNA\u4e8c\u91cd\u3089\u305b\u3093\u306e\u5c0f\u3055\u306a\u6e9d\u306b\u7d50\u5408\u3059\u308b\u30dd\u30ea\u30a2\u30df\u30c9\u6297\u751f\u7269\u8cea\u3067\u3059\u3002 [2] \u30b0\u30e9\u30e0\u967d\u6027\u304a\u3088\u3073\u30b0\u30e9\u30e0\u9670\u6027\u306e\u7d30\u83cc\u306b\u5bfe\u3057\u3066\u6a5f\u80fd\u3057\u307e\u3059\u3002 [3]  DNA\u306b\u7d50\u5408\u3057\u305f\u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u3002 PDB 101d\u304b\u3089\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Netropsin\u306f1951\u5e74\u306bA. C. Finlay\u306b\u3088\u3063\u3066\u6700\u521d\u306b\u8aac\u660e\u3055\u308c\u307e\u3057\u305f\u3002 Streptomyces Netropsis \u5b64\u7acb\u3057\u3066\u3044\u305f\u3002 [4] \u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u306f\u3001\u30d4\u30ed\u30fc\u30eb – \u30a2\u30df\u30b8\u30f3\u6297\u751f\u7269\u8cea\u30af\u30e9\u30b9\u306b\u5c5e\u3057\u3001\u9060\u4f4d\u6a21\u69d8\u3068\u30ec\u30ad\u30b7\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u306e\u985e\u4f3c\u4f53\u3067\u3059\u3002\u4e8c\u672c\u9396DNA\u3068\u30c6\u30c8\u30e9\u30c7\u30f3[TGGGT]\u306e\u30ea\u30c3\u30c1\u306aDNA\u914d\u5217\u306b\u7d50\u5408\u3059\u308b\u3053\u3068\u3092\u597d\u3080 4 \u3001 [5] [6] [7] \u305f\u3060\u3057\u3001\u5358\u4e00\u306e\u9396DNA\u307e\u305f\u306fRNA\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u306e\u7d50\u5408\u306f\u3001\u30d0\u30a4\u30f3\u30c9\u3055\u308c\u305f\u30ec\u30ad\u30b7\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u3068\u5869\u57fa\u5bfe\u3042\u305f\u308a\u7d049\u00b0\u306e\u3088\u308a\u8fd1\u3044\u56de\u8ee2\u306b\u3064\u306a\u304c\u308a\u307e\u3059\u3002 [8] [9] \u967d\u6027\u306e\u30b9\u30fc\u30d1\u30fc\u30b9\u30d4\u30e9\u30ea\u30bc\u30fc\u30b7\u30e7\u30f3\u306b\u3088\u308a\u3001\u8ca0\u306e\u30b9\u30fc\u30d1\u30fc\u30b9\u30d1\u30a4\u30e9\u30eb\u5316\u3092\u5897\u52a0\u3055\u305b\u306a\u304c\u3089DNA\u3092\u7de9\u548c\u3057\u307e\u3059\u3002 [\u5341] \u7d50\u5408\u30e1\u30ab\u30cb\u30ba\u30e0\u306f\u307e\u3060\u5b8c\u5168\u306b\u660e\u3089\u304b\u306b\u3055\u308c\u3066\u3044\u307e\u305b\u3093\u3002 [11] \u816b\u760d\u306b\u5bfe\u3059\u308b\u30a2\u30eb\u30ad\u30e9\u30f3\u30b8\u30a2\u3068\u3057\u3066\u3001\u307e\u305f\u306f\u4e8c\u672c\u9396DNA\u306e\u86cd\u5149\u30de\u30fc\u30ad\u30f3\u30b0\u306b\u4f7f\u7528\u3055\u308c\u308b\u3088\u3046\u306b\u3001\u3055\u307e\u3056\u307e\u306a\u9060\u8ddd\u96e2\u8a98\u5c0e\u4f53\u304c\u958b\u767a\u3055\u308c\u3066\u3044\u307e\u3059\u3002 [12\u756a\u76ee] [13] [14] \u2191 a b c d \u305d\u3046\u3067\u3059  \u30c7\u30fc\u30bf\u30b7\u30fc\u30c8 Netropsin dihydrochloride 2013\u5e7411\u670824\u65e5\u306b\u30a2\u30af\u30bb\u30b9\u3057\u305fSigma-Aldrich\u3067\uff08 PDF \uff09\u3002  \u2191  M. P.\u30d0\u30ec\u30c3\u30c8\u3001C\u3002G\u3002\u30b8\u30a7\u30e0\u30e1\u30eb\u3001C\u3002J\u3002\u30b5\u30c3\u30af\u30ea\u30f3\u30b0\uff1a \u6297\u611f\u67d3\u5264\u3068\u3057\u3066\u306e\u30de\u30a4\u30ca\u30fc\u30b0\u30eb\u30fc\u30d6\u30d0\u30a4\u30f3\u30c0\u30fc\u3002 \u306e\uff1a \u85ac\u7406\u5b66\u3068\u6cbb\u7642\u3002 \u30d0\u30f3\u30c9139\u3001\u30ca\u30f3\u30d0\u30fc1\u30012013\u5e747\u6708\u3001S\u300212\u201323\u3001doi\uff1a 10.1016\/j.pharmthera.2013.03.002 \u3002 PMID 23507040 \u3002  \u2191  C. Zimmer\u3001U\u3002W\u00e4hnert\uff1a \u975e\u4ecb\u5165DNA\u7d50\u5408\u30ea\u30ac\u30f3\u30c9\uff1a\u76f8\u4e92\u4f5c\u7528\u306e\u7279\u7570\u6027\u3068\u3001\u907a\u4f1d\u7269\u8cea\u306e\u751f\u7269\u7269\u7406\u5b66\u7684\u3001\u751f\u5316\u5b66\u7684\u304a\u3088\u3073\u751f\u7269\u5b66\u7684\u8abf\u67fb\u306e\u30c4\u30fc\u30eb\u3068\u3057\u3066\u306e\u305d\u308c\u3089\u306e\u4f7f\u7528\u3002 \u306e\uff1a \u751f\u7269\u7269\u7406\u5b66\u304a\u3088\u3073\u5206\u5b50\u751f\u7269\u5b66\u306e\u9032\u6b69\u3002 \u30d0\u30f3\u30c947\u3001\u30ca\u30f3\u30d0\u30fc1\u30011986\u3001S\u300231\u2013112\u3001 PMID 2422697 \u3002  \u2191  A.C. Finlay\u3001F\u3002A\u3002Hochstein\u3001B\u3002A\u3002Sobin\u3001\u304a\u3088\u3073F. X. Murphy\u3001 \u6df7\u96d1\u3059\u308b\u3002\u5316\u5b66\u3002 Soc\u3002  \u4e03\u5341\u4e09 341\u2013343\uff081951\uff09\u3002 doi\uff1a 10.1021\/JA01145A113 \u3002  \u2191  M. L. Kopka\u3001C\u3002Yoon\u3001D\u3002Goodsell\u3001P\u3002Pjura\u3001\u304a\u3088\u3073R.E.\u30c7\u30a3\u30c3\u30ab\u30fc\u30bd\u30f3\u3001 J.\u30e2\u30eb\u3002 Biol\u3002  183 553\u2013563\uff081985\uff09  \u2191  M. L. Kopka\u3001C\u3002Yoon\u3001D\u3002Goodsell\u3001P\u3002Pjura\u3001R\u3002E\u3002Dickerson\uff1a \u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u3068\u9060\u8ddd\u96e2\u5f0f\u306eDNA-dRug\u7279\u7570\u6027\u306e\u5206\u5b50\u8d77\u6e90\u3002 \u306e\uff1a \u30a2\u30e1\u30ea\u30ab\u5408\u8846\u56fd\u79d1\u5b66\u30a2\u30ab\u30c7\u30df\u30fc\u306e\u8b70\u4e8b\u9332\u3002 \u7b2c82\u5dfb\u30015\u756a\u30011985\u5e743\u6708\u3001pp\u30021376\u20131380\u3001 PMID 2983343 \u3002 PMC 397264 \uff08\u7121\u6599\u306e\u5168\u6587\uff09\u3002  \u2191  B.\u30d1\u30ac\u30ce\u3001I\u3002Foticchia\u3001S\u3002DeTito\u3001C\u3002A\u3002Mattia\u3001L\u3002Mayol\u3001E\u3002Novellino\u3001A\u3002Randazzo\u3001C\u3002Giancola\uff1a \u30b8\u30a2\u30b9\u30de\u30a4\u30b7\u30f3A\u8a98\u5c0e\u4f53\u306eg-quadruplex\u69cb\u9020[D\uff08TGGGGT\uff09]]\uff084\uff09\u306e\u9078\u629e\u7684\u7d50\u5408\u3002 \u306e\uff1a \u6838\u9178\u30b8\u30e3\u30fc\u30ca\u30eb\u3002 \u30d0\u30f3\u30c92010\u30012010\u3001S.\u30012\uff1a 10.4061\/2010\/247137 \u3002 PMID 20725616 \u3002 PMC 2915651 \uff08\u7121\u6599\u306e\u5168\u6587\uff09\u3002  \u2191  G. 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Malcolm\u3001 J.\u30e2\u30eb\u3002 Biol\u3002  167 211\u2013216\uff081983\uff09  \u2191  H.\u601d\u8003\u3001H\u3002\u30d9\u30a2\u3001R\u3002\u30ac\u30fc\u30b5\u30fc\u3001G\u3002\u30d0\u30fc\u30af\u30cf\u30fc\u30c8\u3001 \u30d7\u30ed\u30b0\u30e9\u30e0\u3002\u30b3\u30ed\u30a4\u30c9\u3002\u30dd\u30ea\u30e0\u3002 SCI\u3002  99 45\u201354\uff081995\uff09\u3002  \u2191  J.\u30ea\u30c3\u30d7\u30d5\u30a1\u30fc\u30c8\u3001S\u3002Klijnhout\u3001N\u3002H\u3002Dekker\uff1a \u78c1\u6c17\u30d4\u30f3\u30bb\u30c3\u30c8\u3092\u4f7f\u7528\u3057\u305f\u5c0f\u5206\u5b50\u7d50\u5408\u306e\u306d\u3058\u308c\u30bb\u30f3\u30b7\u30f3\u30b0\u3002 \u306e\uff1a \u6838\u9178\u7814\u7a76\u3002 \u30d0\u30f3\u30c938\u3001\u756a\u53f720\u30012010\u5e7411\u6708\u3001S\u30027122\u20137132\u3001doi\uff1a 10.1093\/nar\/gkq598 \u3002 PMID 20624816 \u3002 PMC 2978369 \uff08\u7121\u6599\u306e\u5168\u6587\uff09\u3002  \u2191  Y.\u30d5\u30a1\u30f3\u3001V\u3002R\u3002\u30e2\u30ea\u30b9\u3001G\u3002M\u3002\u30ea\u30f3\u30ac\u30f3\u30ac\u3001E\u3002C\u3002\u30ed\u30f3\u30b0\u3001W\u3002\u30b5\u30a6\u30b9\u30e9\u30f3\u30c9\uff1a \u30b2\u30ce\u30e0\u3092\u6a19\u7684\u3068\u3057\u305f\u85ac\u7269\u8a2d\u8a08\uff1a\u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3DNA\u76f8\u4e92\u4f5c\u7528\u306e\u7406\u89e3\u3002 \u306e\uff1a Open Conference Proceedings Journal\u3002 \u30d0\u30f3\u30c91\u30012010\u3001S\u3002157\u2013163\u3001 PMID 21297883 \u3002 PMC 3032215 \uff08\u7121\u6599\u306e\u5168\u6587\uff09\u3002  \u2191  G. S.\u30ab\u30fc\u30f3\u3001A\u3002\u30b7\u30e3\u30fc\u3001Zia-ur-Rehman\u3001D\u3002BA\uff1a DNA\u30de\u30a4\u30ca\u30fc\u30b0\u30eb\u30fc\u30d6\u7d50\u5408\u5264\u306e\u5316\u5b66\u3002 \u306e\uff1a Journal of Photochemistry and Photobiology\u3002 B\u3001\u751f\u7269\u5b66\u3002 \u7b2c115\u5dfb\u30012012\u5e7410\u6708\u3001pp\u3002105\u2013118\u3001doi\uff1a 10.1016\/j.jphotobiol.2012.07.003 \u3002 PMID 22857824 \u3002  \u2191  C.\u30d0\u30a4\u30ea\u30fc\u3001J\u3002B\u3002\u30c1\u30a7\u30a2\uff1a \u30b7\u30fc\u30b1\u30f3\u30b9\u56fa\u6709\u306eDNA\u30de\u30a4\u30ca\u30fc\u30b0\u30eb\u30fc\u30d6\u30d0\u30a4\u30f3\u30c0\u30fc\u3002\u30cd\u30c3\u30c8\u30ed\u30c3\u30d7\u30b7\u30f3\u304a\u3088\u3073\u9060\u4f4d\u30de\u30a4\u30b7\u30f3\u985e\u4f3c\u4f53\u306e\u8a2d\u8a08\u3068\u5408\u6210\u3002 \u306e\uff1a \u751f\u4f53\u8abf\u7bc0\u5316\u5b66\u3002 \u7b2c9\u5dfb\u30015\u30011998 SEP-OCT\u3001pp\u3002513\u2013538\u3001doi\uff1a 10.1021\/BC980008M \u3002 PMID 9736486 \u3002  \u2191  T. Vaijayanthi\u3001T\u3002Bando\u3001G\u3002N\u3002Pandian\u3001H\u3002Sugiyama\uff1a \u30b7\u30fc\u30b1\u30f3\u30b9\u9078\u629e\u7684DNA\u30d7\u30ed\u30fc\u30d6\u3068\u3057\u3066\u306e\u30d4\u30ed\u30fc\u30eb – \u30a4\u30df\u30c0\u30be\u30fc\u30eb\u30dd\u30ea\u30a2\u30df\u30c9 – \u30d5\u30eb\u30aa\u30ed\u30d5\u30a9\u30a2\u30b3\u30f3\u30b8\u30e5\u30b2\u30fc\u30c8\u306e\u9032\u884c\u3068\u898b\u901a\u3057\u3002 \u306e\uff1a Chembiochem \u7b2c13\u5dfb\u3001\u756a\u53f715\u30012012\u5e7410\u6708\u3001pp\u30022170\u20132185\u3001doi\uff1a 10,1002\/cbic.201200451 \u3002 PMID 23023993 \u3002  \u3053\u306e\u8a18\u4e8b\u3067\u306f\u3001\u5065\u5eb7\u554f\u984c\u3092\u6271\u3044\u307e\u3059\u3002\u5f7c\u306f\u4ed5\u3048\u307e\u3059 \u3044\u3044\u3048 \u81ea\u5df1\u8a3a\u65ad\u3068\u4ea4\u63db \u3044\u3044\u3048 \u533b\u5e2b\u306b\u3088\u308b\u8a3a\u65ad\u3002\u5065\u5eb7\u554f\u984c\u306b\u95a2\u3059\u308b\u30e1\u30e2\u306b\u6ce8\u610f\u3057\u3066\u304f\u3060\u3055\u3044\uff01        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4      (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/19578#breadcrumbitem","name":"Netropsin -Wikipedia"}}]}]