[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/21212#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/21212","headline":"\u500b\u3005\u306e\u30a2\u30af\u30ec\u30aa\u30c1\u30c9\u591a\u578b\u3068\u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","name":"\u500b\u3005\u306e\u30a2\u30af\u30ec\u30aa\u30c1\u30c9\u591a\u578b\u3068\u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","description":"before-content-x4 DNA\u5206\u5b501\u306f\u3001\u5358\u4e00\u306e\u5869\u57fa\u5bfe\u306eDNA\u5206\u5b502\u3068\u306f\u7570\u306a\u308a\u307e\u3059\u3002 \u30d3\u30c7\u30aa\uff1a\u4f53\u91cd\u3078\u306e\u30b9\u30cb\u30c3\u30d7\u3068\u305d\u306e\u5f71\u97ff \u7528\u8a9e\u3067 \u500b\u3005\u306edump\u5b50 \uff08 SNP \u3001Engl\u3002 s \u30a4\u30f3\u30b0\u30eb n \u30a6\u30af\u30ec\u30aa\u30c1\u30c9 p \u30aa\u30ea\u30e2\u30fc\u30d5\u30a3\u30ba\u30e0 ;\u5b9f\u9a13\u7528\u306e\u5c02\u9580\u7528\u8a9e\u3067\u8a71\u3055\u308c\u3066\u3044\u308b\uff1a\u300cSnip\u300d\uff09\u5358\u4e00\u306e\u30d9\u30fc\u30b9\u30da\u30a2\u306e\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u306f\u3001\u88dc\u5b8c\u7684\u306aDNA\u4e8c\u91cd\u9396\u3067\u53c2\u7167\u3055\u308c\u307e\u3059\u3002 SNP\u306f\u7d99\u627f\u3055\u308c\u3001\u907a\u4f1d\u6027\u306e\u907a\u4f1d\u7684\u5909\u7570\u4f53\u3067\u3059\u3002\u901a\u5e38\u3001\u65b0\u3057\u304f\u767a\u751f\u3057\u305f\u5909\u5316\u3092\u6307\u3059\u7a81\u7136\u5909\u7570\u306e\u6982\u5ff5\u306f\u3001\u3053\u308c\u3068\u6982\u5ff5\u7684\u306b\u533a\u5225\u3055\u308c\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002 after-content-x4 SNP\u306f\u3001\u30d2\u30c8\u30b2\u30ce\u30e0\u306e\u3059\u3079\u3066\u306e\u907a\u4f1d\u7684\u5909\u7570\u306e\u7d0490\uff05\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u3089\u306f\u7b49\u3057\u304f\u73fe\u308c\u307e\u305b\u3093\u304c\u3001\u7279\u5b9a\u306e\u9818\u57df\u3067\u306f\u4e0d\u5747\u4e00\u306b\u898b\u3048\u307e\u3059\u3002\u3059\u3079\u3066\u306eSNP\u306e3\u5206\u306e2\u306f\u3001\u30b7\u30c8\u30b7\u30f3\u3068\u30c1\u30df\u30f3\u3068\u306e\u4ea4\u63db\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u810a\u690e\u52d5\u7269\u306e\u30b2\u30ce\u30e0\u306e\u30b7\u30c8\u30b7\u30f3\u304c\u30e1\u30c1\u30eb\u5316\u306b\u3088\u308a5-\u30e1\u30c1\u30eb\u30b7\u30c8\u30b7\u30f3\u306b\u5909\u63db\u3055\u308c\u3001\u30c1\u30df\u30f3\u3092\u975e\u96e3\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3067\u3059\u3002 after-content-x4 SNP\u306f\u3001\u975e\u30a8\u30f3\u30b3\u30fc\u30c9\u907a\u4f1d\u5b50\u30bb\u30af\u30b7\u30e7\u30f3\uff08\u907a\u4f1d\u5b50\u306e\u5916\u5074\u304a\u3088\u3073\u30a4\u30f3\u30c8\u30ed\u30f3\u306e\u5916\u5074\uff09\u307e\u305f\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u8ee2\u5199\u3055\u308c\u308b\u907a\u4f1d\u5b50\u5207\u7247\u3092\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u5f8c\u8005\u3067\u306f\u3001SO","datePublished":"2022-09-21","dateModified":"2022-09-21","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/2\/2e\/Dna-SNP.svg\/220px-Dna-SNP.svg.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/2\/2e\/Dna-SNP.svg\/220px-Dna-SNP.svg.png","height":"141","width":"220"},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/21212","wordCount":1498,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4 DNA\u5206\u5b501\u306f\u3001\u5358\u4e00\u306e\u5869\u57fa\u5bfe\u306eDNA\u5206\u5b502\u3068\u306f\u7570\u306a\u308a\u307e\u3059\u3002 \u30d3\u30c7\u30aa\uff1a\u4f53\u91cd\u3078\u306e\u30b9\u30cb\u30c3\u30d7\u3068\u305d\u306e\u5f71\u97ff \u7528\u8a9e\u3067 \u500b\u3005\u306edump\u5b50 \uff08 SNP \u3001Engl\u3002  s \u30a4\u30f3\u30b0\u30eb  n \u30a6\u30af\u30ec\u30aa\u30c1\u30c9 p \u30aa\u30ea\u30e2\u30fc\u30d5\u30a3\u30ba\u30e0 ;\u5b9f\u9a13\u7528\u306e\u5c02\u9580\u7528\u8a9e\u3067\u8a71\u3055\u308c\u3066\u3044\u308b\uff1a\u300cSnip\u300d\uff09\u5358\u4e00\u306e\u30d9\u30fc\u30b9\u30da\u30a2\u306e\u30d0\u30ea\u30a8\u30fc\u30b7\u30e7\u30f3\u306f\u3001\u88dc\u5b8c\u7684\u306aDNA\u4e8c\u91cd\u9396\u3067\u53c2\u7167\u3055\u308c\u307e\u3059\u3002 SNP\u306f\u7d99\u627f\u3055\u308c\u3001\u907a\u4f1d\u6027\u306e\u907a\u4f1d\u7684\u5909\u7570\u4f53\u3067\u3059\u3002\u901a\u5e38\u3001\u65b0\u3057\u304f\u767a\u751f\u3057\u305f\u5909\u5316\u3092\u6307\u3059\u7a81\u7136\u5909\u7570\u306e\u6982\u5ff5\u306f\u3001\u3053\u308c\u3068\u6982\u5ff5\u7684\u306b\u533a\u5225\u3055\u308c\u306a\u3051\u308c\u3070\u306a\u308a\u307e\u305b\u3093\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4SNP\u306f\u3001\u30d2\u30c8\u30b2\u30ce\u30e0\u306e\u3059\u3079\u3066\u306e\u907a\u4f1d\u7684\u5909\u7570\u306e\u7d0490\uff05\u3092\u8868\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u3089\u306f\u7b49\u3057\u304f\u73fe\u308c\u307e\u305b\u3093\u304c\u3001\u7279\u5b9a\u306e\u9818\u57df\u3067\u306f\u4e0d\u5747\u4e00\u306b\u898b\u3048\u307e\u3059\u3002\u3059\u3079\u3066\u306eSNP\u306e3\u5206\u306e2\u306f\u3001\u30b7\u30c8\u30b7\u30f3\u3068\u30c1\u30df\u30f3\u3068\u306e\u4ea4\u63db\u3067\u69cb\u6210\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u810a\u690e\u52d5\u7269\u306e\u30b2\u30ce\u30e0\u306e\u30b7\u30c8\u30b7\u30f3\u304c\u30e1\u30c1\u30eb\u5316\u306b\u3088\u308a5-\u30e1\u30c1\u30eb\u30b7\u30c8\u30b7\u30f3\u306b\u5909\u63db\u3055\u308c\u3001\u30c1\u30df\u30f3\u3092\u975e\u96e3\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u305f\u3081\u3067\u3059\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4SNP\u306f\u3001\u975e\u30a8\u30f3\u30b3\u30fc\u30c9\u907a\u4f1d\u5b50\u30bb\u30af\u30b7\u30e7\u30f3\uff08\u907a\u4f1d\u5b50\u306e\u5916\u5074\u304a\u3088\u3073\u30a4\u30f3\u30c8\u30ed\u30f3\u306e\u5916\u5074\uff09\u307e\u305f\u306f\u30bf\u30f3\u30d1\u30af\u8cea\u306b\u8ee2\u5199\u3055\u308c\u308b\u907a\u4f1d\u5b50\u5207\u7247\u3092\u30b3\u30fc\u30c7\u30a3\u30f3\u30b0\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u5f8c\u8005\u3067\u306f\u3001SO -Called “Silence”\u3068\u306e\u9593\u306b\u533a\u5225\u304c\u884c\u308f\u308c\u307e\u3059\uff08 \u9759\u3051\u3055 \uff09\u307e\u305f\u306f\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u914d\u5217\u3092\u5909\u5316\u3055\u305b\u306a\u3044\u300c\u540c\u7fa9\u8a9e\u300dSNP\u306f\u3001\u907a\u4f1d\u30b3\u30fc\u30c9\u306e\u5909\u6027\u306e\u305f\u3081\u306b\u5c0e\u51fa\u3055\u308c\u305f\u30a2\u30df\u30ce\u9178\u914d\u5217\u3068\u300c\u975e\u30b7\u30ce\u30cb\u30e0\u300dSNP\u3092\u5909\u5316\u3055\u305b\u305a\u3001\u95a2\u4fc2\u3059\u308b\u30b3\u30c9\u30f3\u306b\u30a2\u30df\u30ce\u9178\u5909\u5316\u3092\u3082\u305f\u3089\u3057\u307e\u3059\u3002 SNP\u304c\u975e\u30a8\u30f3\u30b3\u30fc\u30c9\u30b2\u30ce\u30e0\u9818\u57df\u306b\u3042\u308b\u5834\u5408\u3067\u3082\u3001z\u306e\u5834\u5408\u3001\u907a\u4f1d\u5b50\u8ee2\u5199\uff08\u8abf\u7bc0SNP\uff09\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 B. DNA\u5207\u7247\u3067\u306f\u3001\u8ee2\u5199\u56e0\u5b50\uff08\u30a8\u30f3\u30cf\u30f3\u30b5\u30fc\u3001\u30b5\u30a4\u30ec\u30f3\u30b5\u30fc\uff09\u307e\u305f\u306fRNA\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\uff08\u30d7\u30ed\u30e2\u30fc\u30bf\u30fc\uff09\u306b\u7d50\u5408\u3057\u307e\u3059\u3002\u30a4\u30f3\u30c8\u30ed\u30f3\u306eSNP\u3092\u4ecb\u3057\u3066\u3001z\u3002 B.\u307e\u305f\u3001\u300c\u4e0d\u53ef\u89e3\u306a\u300d\u30b9\u30d7\u30e9\u30a4\u30b9\u30b5\u30a4\u30c8\u3002 SNP\u306f\u300c\u6210\u529f\u3057\u305f\u70b9\u5909\u7570\u300d\u3068\u3082\u547c\u3070\u308c\u307e\u3059\u3002 H.\u96c6\u56e3\u306e\u907a\u4f1d\u5b50\u30d7\u30fc\u30eb\u3067\u3042\u308b\u7a0b\u5ea6\u666e\u53ca\u3057\u3066\u3044\u308b\u907a\u4f1d\u7684\u5909\u5316\u3068\u3057\u3066\u3001\u3064\u307e\u308a\u907a\u4f1d\u7684\u5909\u5316\u306b\u306a\u3063\u3066\u3044\u307e\u3059\u3002\u4e00\u90e8\u306eSNP\u306fz\u3092\u76f8\u95a2\u3055\u305b\u307e\u3059\u3002 B.\u7279\u5b9a\u306e\u611f\u67d3\u75c7\u306b\u5bfe\u3059\u308b\u751f\u7269\u306e\u7279\u5b9a\u306e\u53cd\u5fdc\u307e\u305f\u306f\u7279\u5225\u306a\u7269\u8cea\u3068\u306e\u63a5\u89e6\u3002\u305d\u308c\u3089\u306e\u79d1\u5b66\u7684\u91cd\u8981\u6027\u306f\u3001\u983b\u7e41\u306a\u767a\u751f\u3068\u9ad8\u3044\u5909\u52d5\u6027\u306b\u3042\u308a\u3001\u307e\u305f\u975e\u5e38\u306b\u8fc5\u901f\u304b\u3064\u7c21\u5358\u306b\u5224\u65ad\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u305d\u306e\u305f\u3081\u3001\u305f\u3068\u3048\u3070\u3001\u5b9a\u91cf\u7684\u7279\u6027\u907a\u4f1d\u5b50\u5ea7\u3001\u3064\u307e\u308a\u5b9a\u91cf\u7684\u7279\u5fb4\u306e\u767a\u73fe\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u67d3\u8272\u4f53\u30bb\u30af\u30b7\u30e7\u30f3\u3001\u500b\u4eba\u306e\u8b58\u5225\u306e\u305f\u3081\u306e\u67d3\u8272\u4f53\u30bb\u30af\u30b7\u30e7\u30f3\u3001\u304a\u3088\u3073\u95a2\u4fc2\u8a3a\u65ad\u306e\u5834\u5408\u3060\u3051\u3067\u306a\u304f\u3001\u85ac\u7269\u8010\u6027\u306a\u3069\u306e\u7814\u7a76\u306b\u304a\u3044\u3066\u3082\u4f7f\u7528\u3055\u308c\u308b\u7406\u7531\u3067\u3059\u3002\u4e00\u822c\u7684\u306aSNP\u306e\u7a0b\u5ea6\u306f\u3001\u907a\u4f1d\u7684\u7cfb\u56f3\u306b\u5f79\u7acb\u3061\u3001\u95a2\u4fc2\u307e\u305f\u306f\u6bd4\u7387\u306e\u7a0b\u5ea6\u3092\u6c7a\u5b9a\u3057\u307e\u3059\u3002 \u500b\u3005\u306e\u6761\u7d04\u306e\u591a\u578b\u3092\u7279\u5b9a\u3059\u308b\u65b9\u6cd5\u306f\u3001\u4f8b\u3048\u3070B. DNA\u30b7\u30fc\u30b1\u30f3\u30b9\u3001\u30de\u30a4\u30af\u30ed\u30a2\u30ec\u30a4\u3001\u304a\u3088\u3073\u30a2\u30ec\u30eb\u7279\u7570\u7684\u30aa\u30ea\u30b4\u30cc\u30af\u30ec\u30aa\u30c1\u30c9\u3068\u7d44\u307f\u5408\u308f\u305b\u3066\u3001\u30dd\u30ea\u30e1\u30e9\u30fc\u30bc\u9023\u9396\u53cd\u5fdc\u304a\u3088\u3073\u7b49\u6e29DNA\u5897\u5e45\u3002 \u904e\u53bb\u306b\u306f\u3001\u7279\u306b\u975e\u30a8\u30f3\u30b3\u30fc\u30c9\u907a\u4f1d\u5b50\u30bb\u30af\u30b7\u30e7\u30f3\u306b\u3042\u308b\u5834\u5408\u3001SNP\u306b\u306f\u307b\u3068\u3093\u3069\u6ce8\u610f\u304c\u6255\u308f\u308c\u3066\u3044\u307e\u305b\u3093\u3067\u3057\u305f\u3002\u305d\u308c\u3089\u306f\u307b\u3068\u3093\u3069\u610f\u5473\u304c\u306a\u3044\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u5927\u898f\u6a21\u306a\u30b2\u30ce\u30e0\u5168\u4f53\u306e\u95a2\u9023\u7814\u7a76\u3092\u901a\u3058\u3066\u3001\u4e00\u90e8\u306eSNP\u306f\u8907\u96d1\u3067\u307b\u3068\u3093\u3069\u7406\u89e3\u3055\u308c\u3066\u3044\u306a\u3044\u65b9\u6cd5\u3067\u7279\u5b9a\u306e\u75be\u60a3\u306e\u30ea\u30b9\u30af\u306b\u5f71\u97ff\u3092\u4e0e\u3048\u308b\u3053\u3068\u304c\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u3001\u305f\u3068\u3048\u3070\u3001\u30d2\u30c8\u907a\u4f1d\u5b50\u306e\u500b\u3005\u306e\u975e\u30a8\u30f3\u30b3\u30fc\u30c9SNP\u306b\u9069\u7528\u3055\u308c\u307e\u3059 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Bersaggieri\u3001P.at Saubets u\u3002 a\u3002\uff1a \u30e9\u30af\u30bf\u30fc\u30bc\u907a\u4f1d\u5b50\u306b\u304a\u3051\u308b\u5f37\u529b\u306a\u6700\u8fd1\u306e\u30dd\u30b8\u30c6\u30a3\u30d6\u9078\u629e\u306e\u907a\u4f1d\u7684\u7f72\u540d\u3002 \u306e\uff1a American Journal of Human Genetics\u3002 \u30d0\u30f3\u30c974\u3001\u30ca\u30f3\u30d0\u30fc6\u30012004\u5e746\u6708\u3001S\u30021111\u20131120\u3001 doi\uff1a10.1086\/421051 \u3001 PMID 15114531 \u3001 PMC 1182075 \uff08\u7121\u6599\u306e\u5168\u6587\uff09\u3002  \u2191  Friederike Flachsbart\u3001Janina Dose\u3001Liljana Gentschew\u3001Claudia Geismann\u3001 \u5225\u306e29\u4eba\u306e\u8457\u8005\u3082 \u30a2\u30eb\u30e0\u30fc\u30c8\u30cd\u30d9\u30eb\uff1a \u4eba\u9593\u306e\u9577\u5bff\u907a\u4f1d\u5b50FOXO3\u306b\u304a\u3051\u308b2\u3064\u306e\u6a5f\u80fd\u7684\u30d0\u30ea\u30a2\u30f3\u30c8\u306e\u8b58\u5225\u3068\u7279\u6027\u8a55\u4fa1\u3002 \u306e\uff1a \u81ea\u7136\u30b3\u30df\u30e5\u30cb\u30b1\u30fc\u30b7\u30e7\u30f3 8\/2017\uff1a2063\u30011\u201312\u3002 doi\uff1a 10.1038\/s41467-017-02183-y \u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/21212#breadcrumbitem","name":"\u500b\u3005\u306e\u30a2\u30af\u30ec\u30aa\u30c1\u30c9\u591a\u578b\u3068\u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2"}}]}]