[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/4928#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/4928","headline":"\u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","name":"\u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2","description":"before-content-x4 \u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc \u65e2\u5b58\u306e\u69cb\u9020\u30c7\u30fc\u30bf\uff1a 1eho \u3001 1ehq \u3001 1kcj \u3001 1p0i \u3001 1p0m \u3001 1p0p \u3001 1p0q \u3001 1xlu \u3001 1xlv","datePublished":"2020-10-15","dateModified":"2020-10-15","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/8d\/Protein_BCHE_PDB_1p0i.png\/250px-Protein_BCHE_PDB_1p0i.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/8d\/Protein_BCHE_PDB_1p0i.png\/250px-Protein_BCHE_PDB_1p0i.png","height":"229","width":"250"},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/4928","wordCount":1967,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4\u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc  \u65e2\u5b58\u306e\u69cb\u9020\u30c7\u30fc\u30bf\uff1a 1eho \u3001 1ehq \u3001 1kcj \u3001 1p0i \u3001 1p0m \u3001 1p0p \u3001 1p0q \u3001 1xlu \u3001 1xlv \u3001 1xlw \u3001 2J4C \u3001 2pm8 \u3001 2WID \u3001 2wif \u3001 2\u30a6\u30a3\u30c3\u30b0 \u3001 2wij \u3001 2wik \u3001 2wil \u3001 2wsl \u3001 2xmb \u3001 2xmc \u3001 2xmd \u3001 2xmg \u3001 2xqf \u3001 2xqg \u3001 2xqi \u3001 2xqj \u3001 2xqk \u3001 2y1k \u3001 3djy \u3001 3dkk \u3001 3o9m \u3001 4aqd \u3001 4AXB \u3001 4b0o \u3001 4b0p \u3001 4bbz \u3001 4bds \u3001 4tpk  \u30d2\u30c8\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7279\u6027 \u8cea\u91cf\/\u9577\u3055\u306e\u4e00\u6b21\u69cb\u9020 574\u30a2\u30df\u30ce\u9178 \u7b2c\u56db\u7d00\u69cb\u9020\u306b\u7d9a\u767a\u3057\u307e\u3059 \u30db\u30e2\u30c3\u30c8\u30c8\u30e9\u30e0 \u8b58\u5225\u5b50 \u907a\u4f1d\u5b50\u540d Bche ; Che1 \u5916\u90e8ID  \u9175\u7d20\u5206\u985e EC\u3001\u30ab\u30c6\u30b4\u30ea 3.1.1.8 \u3001\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc \u53cd\u5fdc Versefung \u57fa\u677f \u30a2\u30b7\u30eb\u30b3\u30ea\u30f3 +H\u3002 2 o \u88fd\u54c1 \u30b3\u30ea\u30f3 +\u30ab\u30eb\u30dc\u30ad\u30b7\u30e9\u30c3\u30c8 \u8d77\u3053\u308b \u76f8\u540c\u6027 \u30ab\u30eb\u30dc\u30ad\u30b7\u30eb\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc  \u30aa\u30fc\u30d0\u30fc\u30e9\u30a4\u30c9\u3059\u308b\u5206\u985e\u7fa4 \u5f26 \u30aa\u30eb\u30bd\u30ed\u30b8\u30e5  \u4eba \u30cf\u30a6\u30b9\u30de\u30a6\u30b9 \u304a\u5165\u308a\u304f\u3060\u3055\u3044 590  12038  \u8a2d\u5b9a ensg00000114200  Ensmusg000027792  uniprot P06276  Q03311  refseq\uff08mRNA\uff09 NM_000055  NM_009738  refseq\uff08\u30bf\u30f3\u30d1\u30af\u8cea\uff09 NP_000046  NP_033868  \u30dd\u30b9\u30bf\u30fc  CHR 3\uff1a165.77-165.84 MB    CHR 3\uff1a73.64-73.71 MB   PubMed\u691c\u7d22 590  12038         (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4 \u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc \uff08\u30d6\u30c1\u30eb\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u3001\u30d3\u30fc\u30c1\uff09\u306f\u3001\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30eb\u306e\u30a8\u30b9\u30c6\u30eb\u7d50\u5408\u306e\u52a0\u6c34\u5206\u89e3\u3092\u89e6\u5a92\u3059\u308b\u9175\u7d20\u3067\u3059\u3002\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u306b\u52a0\u3048\u3066\u3001\u3053\u308c\u3089\u306e\u7269\u8cea\u3092\u5206\u89e3\u3059\u308b\u305f\u3081\u306b\u810a\u7d22\u52d5\u7269\u306e\u4ee3\u8b1d\u306b\u4e0d\u53ef\u6b20\u3067\u3059\u3002\u4eba\u9593\u306eBCHE\u907a\u4f1d\u5b50\u306e\u5909\u7570\u306f\u3001\u307e\u308c\u306a\u6b20\u4e4f\u75c7BCHE\u6b20\u4e4f\u75c7\u306b\u3064\u306a\u304c\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002 [\u521d\u3081] \u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u306f\u3001\u30a2\u30b9\u30d4\u30ea\u30f3\u3001\u30b3\u30ab\u30a4\u30f3\u3001\u30d8\u30ed\u30a4\u30f3\u306a\u3069\u3001\u30b3\u30ea\u30f3\u3068\u306f\u7570\u306a\u308b\u30a2\u30eb\u30b3\u30fc\u30eb\u6210\u5206\u3092\u542b\u3080\u7570\u306a\u308b\u30a8\u30b9\u30c6\u30eb\u3092\u5206\u5272\u3059\u308b\u3053\u3068\u3082\u3067\u304d\u307e\u3059\u3002\u30b8\u30e3\u30ac\u30a4\u30e2\u690d\u7269\u306e\u7dd1\u8272\u306e\u90e8\u5206\u3067\u767a\u751f\u3059\u308b\u30b0\u30ea\u30b3\u30a2\u30eb\u30ab\u30ed\u30a4\u30c9\uff08\u30a2\u30eb\u30d5\u30a1\u30bd\u30e9\u30cb\u30f3\u3001\u30a2\u30eb\u30d5\u30a1\u30c1\u30e3\u30b3\u30cb\u30f3\uff09\u306b\u3088\u3063\u3066\u963b\u5bb3\u3055\u308c\u307e\u3059\u3002 [2] \u9175\u7d20\u306f\u3001\u4f8b\u3048\u3070\u809d\u81d3\u3001\u8840\u6f3f\u3001\u8178\u7c98\u819c\u3001\u307e\u305f\u306f\u81b5\u81d3\u3067\u591a\u304f\u306e\u7d44\u7e54\u3067\u767a\u751f\u3057\u307e\u3059\u3002\u30b7\u30ca\u30d7\u30b9\u30ae\u30e3\u30c3\u30d7\u306e\u5916\u5074\u306e\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u306e\u52b9\u679c\u3092\u9632\u200b\u200b\u3050\u3079\u304d\u3067\u3042\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u307e\u3059\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u6700\u8fd1\u306e\u7814\u7a76\u3067\u306f\u3001\u7d44\u7e54\u3092\u51e6\u7406\u3059\u308b\u3068\u304d\u306b\u4f7f\u7528\u3055\u308c\u308bDentergens Triton X-100\u304c\u507d\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u3092\u963b\u5bb3\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u307e\u3059\u3002\u305d\u306e\u7d50\u679c\u3001\u3053\u306e\u9175\u7d20\u306e\u91cf\u306f\u591a\u304f\u306e\u7d44\u7e54\u3067\u904e\u5c0f\u8a55\u4fa1\u3055\u308c\u3066\u3044\u307e\u3057\u305f\u3002 [3] \u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u306f\u3001\u306e\u4f7f\u7528\u306b\u95a2\u9023\u3057\u3066\u610f\u5473\u304c\u3042\u308a\u307e\u3059 \u7b4b\u8089\u306e\u518dx \u5168\u8eab\u9ebb\u9154\u306e\u4e00\u90e8\u3068\u3057\u3066\u3002 2\u3064\u306e\u5f1b\u7de9\u85ac\u30df\u30d0\u30af\u30ea\u30a6\u30e0\uff08\u975e\u6975\u5206\u89e3\uff09\u3068\u30b5\u30ad\u30b5\u30e1\u30c8\u30cb\u30a6\u30e0\uff08\u8131\u5206\u6975\uff09\u306e\u77ed\u3044\u671f\u9593\u306f\u3001\u8840\u6f3f\u4e2d\u306e\u85ac\u7269\u306e\u6025\u901f\u306a\u5206\u89e3\u306b\u3088\u308b\u3082\u306e\u3067\u3059\uff08\u7d044\u5206\u3067\u30df\u30d0\u30af\u30ea\u30a6\u30e0\u3001\u30b5\u30ad\u30b5\u30e1\u30c8\u30cb\u30a6\u30e0\u306f\u7d041\u5206\u3067\u6e1b\u5c11\u3057\u307e\u3057\u305f\uff09\u3002\u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u306e\u6b20\u5982\uff08\u9175\u7d20\u6d3b\u6027\u306e\u55aa\u5931\u306f75\uff05\u3092\u8d85\u3048\u307e\u3059\u3002\u305f\u3068\u3048\u3070\u3001\u809d\u6a5f\u80fd\u969c\u5bb3\u3001\u60aa\u6027\u816b\u760d\u3001\u598a\u5a20\u3001\u598a\u5a20\u306a\u3069\uff09\u7d50\u679c\u3068\u3057\u3066\u751f\u3058\u308b\u62e1\u5f35\u547c\u5438\u9ebb\u75fa\u306e\u305f\u3081\u3001\u60a3\u8005\u306f\u7b4b\u8089\u306e\u6eb6\u89e3\u52b9\u679c\u304c\u6c88\u3080\u307e\u3067\u30ca\u30b3\u30c3\u30c8\u5316\u3055\u308c\u3001\u4eba\u70ba\u7684\u306b\u63db\u6c17\u3059\u308b\u5fc5\u8981\u304c\u3042\u308a\u307e\u3059\uff08\u63db\u6c17\u5f8c – \u63db\u6c17\uff09\u3002 \u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u306e\u3044\u304f\u3064\u304b\u306e\u907a\u4f1d\u7684\u5909\u7570\u306f\u3001\u305f\u3068\u3048\u3070\u3001\u4eba\u53e3\u30b0\u30eb\u30fc\u30d7\u5168\u4f53\u3067\u3001\u5546\u4eba\u3001\u30c7\u30a3\u30fc\u30e9\u30fc\u3001\u30de\u30cd\u30fc\u30ec\u30f3\u30c0\u30fc\u3001\u5927\u898f\u6a21\u306a\u571f\u5730\u6240\u6709\u8005\u306e\u30a4\u30f3\u30c9\u306e\u7bb1\u306e\u30f4\u30a1\u30a4\u30b7\u30e3\u306a\u3069\u306e\u983b\u7e41\u306a\u30a8\u30f3\u30c9\u30ac\u30df\u30fc\u306e\u305f\u3081\u306b\u77e5\u3089\u308c\u3066\u3044\u307e\u3059\u3002 [4] \u9175\u7d20\u306e\u975e\u5b9a\u578b\u5909\u7570\u4f53\u306e\u30db\u30e2\u63a5\u5408\u4f53\u306e\u4eba\u3005\uff08\u5468\u6ce2\u6570\u7d041\uff1a2000\uff09\u306f\u3001\u4e0a\u8a18\u306e\u7b4b\u8089\u5f1b\u7de9\u85ac\u3092\u3086\u3063\u304f\u308a\u3068\u3086\u3063\u304f\u308a\u3068\u52a0\u6c34\u5206\u89e3\u3057\u3001\u8aac\u660e\u3057\u305f\u5408\u4f75\u75c7\u304c\u767a\u751f\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u307e\u3059\u3002\u9175\u7d20\u306e\u6a5f\u80fd\u306f\u3001\u8840\u6e05\u4e2d\u306eSo -Calted Dibucain\u6570\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u6e2c\u5b9a\u3055\u308c\u307e\u3059\u3002\u3053\u306e\u691c\u67fb\u3067\u306f\u3001\u9175\u7d20\u306e\u6d3b\u6027\u306f\u5c40\u6240\u9ebb\u9154\u30b8\u30d6\u30ab\u30a4\u30f3\u3092\u52a0\u3048\u305f\u5f8c\u306b\u6c7a\u5b9a\u3055\u308c\u307e\u3059\u3002 2022\u5e74\u306e\u521d\u3081\u306b\u3001\u535a\u58eb\u3092\u3081\u3050\u308b\u7814\u7a76\u30c1\u30fc\u30e0\u304c\u30b7\u30c9\u30cb\u30fc\u306e\u30a6\u30a7\u30b9\u30c8\u30df\u30fc\u30c9\u5c0f\u5150\u75c5\u9662\u306e\u30ab\u30fc\u30e1\u30eb\u30c6\u30ec\u30fc\u30ba\u30cf\u30ea\u30f3\u30c8\u30f3\u8abf\u67fb\u306e\u7d50\u679c [5] \u305d\u308c\u306f\u3001\u30d6\u30ca\u306e\u6b20\u4e4f\u3068\u7a81\u7136\u306e\u5b50\u4f9b\u306e\u6b7b\u306e\u95a2\u4fc2\u3092\u793a\u5506\u3057\u3066\u3044\u307e\u3059\u3002        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u2191  Uniprot\u30a8\u30f3\u30c8\u30ea  \u2191  S. Darveshin\u3002A\u3002\uff1a \u30d6\u30c1\u30ea\u30eb\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u306e\u795e\u7d4c\u751f\u7269\u5b66\u3002 \u306e\uff1a Nat Rev Neurosci\u3002 \u30d0\u30f3\u30c94\u3001nr\u3002 2\u30012003\u3001S\u3002131-138\u3002  \u2191  B. li u\u3002 a\u3002\uff1a \u8c4a\u5bcc\u306a\u7d44\u7e54\u30d6\u30c1\u30ea\u30eb\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u3068\u30a2\u30bb\u30c1\u30eb\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\u30ce\u30c3\u30af\u30a2\u30a6\u30c8\u30de\u30a6\u30b9\u306b\u304a\u3051\u308b\u305d\u306e\u53ef\u80fd\u306a\u6a5f\u80fd\u3002 \u306e\uff1a j\u795e\u7d4c\u7403\u3002 \u30d0\u30f3\u30c975\u3001nr\u3002 3\u30012000\u5e749\u6708\u3001S\u30021320-11331\u3002  \u2191  I. Manoharan\u3001S\u3002Wieseler\u3001P\u3002G\u3002Layer\u3001O\u3002Lockridge\u3001R\u3002Boopathy\uff1a \u30a4\u30f3\u30c9\u306eVysya\u30b3\u30df\u30e5\u30cb\u30c6\u30a3\u306b\u304a\u3051\u308b\u30d2\u30c8butyrylcholinesterase\u306e\u81ea\u7136\u306b\u767a\u751f\u3059\u308b\u5909\u7570Leu307Pro\u3002 \u306e\uff1a \u85ac\u7406\u907a\u4f1d\u5b66\u3068\u30b2\u30ce\u30df\u30af\u30b9\u3002 \u30d0\u30f3\u30c916\u3001nr\u3002 7\u30012006\u3001S 461-468\u3002 doi\uff1a10.1097\/01.fpc.0000197464.37211.77 \u3002 PMID 16788378 \u3002  \u2191  Deutsche Welle\uff08www.dw.com\uff09\uff1a \u767a\u898b\u3055\u308c\u305f\u7a81\u7136\u306e\u5b50\u3069\u3082\u306e\u6b7b\u306e\u53ef\u80fd\u6027\u306e\u3042\u308b\u539f\u56e0| dw | 2022\u5e745\u670817\u65e5\u3002 2022\u5e745\u670817\u65e5\u306b\u30a2\u30af\u30bb\u30b9 \uff08\u30c9\u30a4\u30c4\u4eba\uff09\u3002         (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki11\/archives\/4928#breadcrumbitem","name":"\u30b7\u30e5\u30fc\u30c9\u30b3\u30ea\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc – \u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2"}}]}]