[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki47\/archives\/15669#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/all2jp\/wiki47\/archives\/15669","headline":"Comretableness-\u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2\u3001\u7121\u6599\u200b\u200b\u767e\u79d1\u4e8b\u5178","name":"Comretableness-\u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2\u3001\u7121\u6599\u200b\u200b\u767e\u79d1\u4e8b\u5178","description":"before-content-x4 combineastatin – \u30c4\u30ea\u30fc\u306b\u3042\u308b\u30b9\u30c6\u30a3\u30eb\u30d9\u30f3\u8a98\u5c0e\u4f53 Combretum Caffris \uff08Eckkl\u3002\uff06Zeyh\u3002\uff09Kuntze\uff08\u3057\u305f\u304c\u3063\u3066\u3001\u95a2\u4fc2\u306e\u540d\u524d\uff09\u3001\u300cAfrican Willow\u300d\u3068\u3082\u547c\u3070\u308c\u3001\u5357\u30a2\u30d5\u30ea\u30ab\u306e\u5cac\u306e\u6771\u90e8\u3067\u6210\u9577\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u3089\u306b\u306f\u30013\u3064\u306e\u5171\u901a\u306e\u69cb\u9020\u7684\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002\u30ea\u30f3\u30b0\u30683\u3064\u306e\u30e1\u30c8\u30ad\u30b7\u30eb\u57fa\u3092\u5099\u3048\u305f\u30ea\u30f3\u30b0B\u306f\u3001\u591a\u304f\u306e\u5834\u5408\u3001\u4f4d\u7f6e3 ‘\u304a\u3088\u30734’\u306b\u7f6e\u304d\u63db\u3048\u3089\u308c\u305f\u30b0\u30eb\u30fc\u30d7\u3067\u3001R-\uff08 – \uff09 – \u7d44\u307f\u5408\u308f\u305b\u305f\u30a8\u30a2\u30b9\u30bf\u30c1\u30f3\u307e\u305f\u306f\u30a8\u30c6\u30cd\u30c3\u30c8\uff08\u69cb\u9020\u306e\u5fc5\u8981\u306a\u525b\u6027\u3092\u4fdd\u8a3c\u3057\u307e\u3059\uff09\u306e\u3088\u3046\u306b\u30a8\u30bf\u30ca\u30f3\u6a4b\u3067\u3059\u3002 \u540d\u524d \u30d1\u30bf\u30fc\u30f3 \u5206\u5b50\u91cf Numer CAS Pubchem\u756a\u53f7 a-1","datePublished":"2023-09-15","dateModified":"2023-09-15","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki47\/archives\/author\/lordneo#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/all2jp\/wiki47\/archives\/author\/lordneo","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/44a4cee54c4c053e967fe3e7d054edd4?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/89\/Combretastatin_A-1.svg\/150px-Combretastatin_A-1.svg.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/89\/Combretastatin_A-1.svg\/150px-Combretastatin_A-1.svg.png","height":"89","width":"150"},"url":"https:\/\/wiki.edu.vn\/all2jp\/wiki47\/archives\/15669","wordCount":753,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4combineastatin  – \u30c4\u30ea\u30fc\u306b\u3042\u308b\u30b9\u30c6\u30a3\u30eb\u30d9\u30f3\u8a98\u5c0e\u4f53 Combretum Caffris \uff08Eckkl\u3002\uff06Zeyh\u3002\uff09Kuntze\uff08\u3057\u305f\u304c\u3063\u3066\u3001\u95a2\u4fc2\u306e\u540d\u524d\uff09\u3001\u300cAfrican Willow\u300d\u3068\u3082\u547c\u3070\u308c\u3001\u5357\u30a2\u30d5\u30ea\u30ab\u306e\u5cac\u306e\u6771\u90e8\u3067\u6210\u9577\u3057\u3066\u3044\u307e\u3059\u3002\u305d\u308c\u3089\u306b\u306f\u30013\u3064\u306e\u5171\u901a\u306e\u69cb\u9020\u7684\u7279\u5fb4\u304c\u3042\u308a\u307e\u3059\u3002\u30ea\u30f3\u30b0\u30683\u3064\u306e\u30e1\u30c8\u30ad\u30b7\u30eb\u57fa\u3092\u5099\u3048\u305f\u30ea\u30f3\u30b0B\u306f\u3001\u591a\u304f\u306e\u5834\u5408\u3001\u4f4d\u7f6e3 ‘\u304a\u3088\u30734’\u306b\u7f6e\u304d\u63db\u3048\u3089\u308c\u305f\u30b0\u30eb\u30fc\u30d7\u3067\u3001R-\uff08 – \uff09 – \u7d44\u307f\u5408\u308f\u305b\u305f\u30a8\u30a2\u30b9\u30bf\u30c1\u30f3\u307e\u305f\u306f\u30a8\u30c6\u30cd\u30c3\u30c8\uff08\u69cb\u9020\u306e\u5fc5\u8981\u306a\u525b\u6027\u3092\u4fdd\u8a3c\u3057\u307e\u3059\uff09\u306e\u3088\u3046\u306b\u30a8\u30bf\u30ca\u30f3\u6a4b\u3067\u3059\u3002 \u540d\u524d \u30d1\u30bf\u30fc\u30f3 \u5206\u5b50\u91cf Numer CAS Pubchem\u756a\u53f7 a-1 combineastatin 3-\u30e1\u30c8\u30c3\u30af\u30b9-6- [\uff08 \u3068 \uff09-2-\uff083.4.5-Trimetoksyfenylo\uff09etenylo] benzeno-1,2-diol  332.13 109971-63-3 6078282 A-4 Combineastatin\uff08CA-4\u307e\u305f\u306fCA4\u306e\u7565\u8a9e\u304c\u4f7f\u7528\u3055\u308c\u307e\u3059\uff09 3-\u30e1\u30c8\u30c3\u30af\u30b9-6- [\uff08 \u3068 \uff09-2-\uff083.4.5-Trimetoksyfenylo\uff09etenylo] benzeno-2-ol  316.35   \uff08 r \uff09 – \uff08 – \uff09 –  Kombretstuta 5- [\uff082 r \uff09-2-\u30d2\u30c9\u30ed\u30c3\u30af\u30b9-2-\uff083.4.5-\u30c8\u30ea\u30e1\u30c8\u30ad\u30b7\u30d5\u30a7\u30cb\u30ed\uff09eThilo] -2-\u30e1\u30c8\u30ad\u30b7\u30d5\u30a7\u30ce\u30fc\u30eb  334.14 82855-09-2 9895264        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u502b\u7406\u30d6\u30ea\u30c3\u30b8\uff08\u30a2\u30b9\u30bf\u30bf\u30c1\u30f3A-1\u3001A-4\u3001\u304a\u3088\u3073B-1\uff09\u3092\u6301\u3064\u5316\u5408\u7269\u306e\u7279\u5fb4\u306f\u6297\u304c\u3093\u52b9\u679c\u3067\u3042\u308a\u3001\u3088\u308a\u5177\u4f53\u7684\u306b\u306f\u3001\u305d\u306e\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u03b2\u3078\u306e\u4ed8\u7740\u306e\u7d50\u679c\u3068\u3057\u3066\u30c1\u30e5\u30fc\u30d6\u30ea\u30f3\u3092\u4e0d\u5b89\u5b9a\u5316\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u6297\u8840\u7ba1\u65b0\u751f\u3067\u3042\u308a\u3001\u3053\u308c\u306b\u3088\u308a\u3001\u5185\u76ae\u304a\u3088\u3073\u7d30\u80de\u6bd2\u6027\u7d30\u80de\u304c\u5897\u52a0\u3059\u308b\u30a2\u30dd\u30c8\u30fc\u30b7\u30b9\u3092\u5f15\u304d\u8d77\u3053\u3057\u307e\u3059\u3002\u81ea\u7136\u754c\u306b\u898b\u3089\u308c\u308b\u5316\u5408\u7269\u306e\u4e2d\u3067\u3001\u30c1\u30e5\u30fc\u30d6\u30ea\u30f3\u3068\u7d30\u80de\u6bd2\u6027\u306f\u30b7\u30b9\u30b3\u30fc\u30e0\u30b9\u30bf\u30c1\u30f3A-4\uff08\u3059\u306a\u308f\u3061\u7570\u6027\u4f53\u304b\u3089\uff09\u3067\u3042\u308b\u3068\u601d\u308f\u308c\u307e\u3059\u304c\u3001A-1\u306f\u7d30\u80de\u6bd2\u6027\u3082\u5f37\u304f\u6a5f\u80fd\u3057\u307e\u3059\u3002\u30a2\u30df\u30ce\u304a\u3088\u3073\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u57fa\u3067\u4f4d\u7f6e3 ‘\u306b\u7f6e\u63db\u3055\u308c\u305f\u5206\u5b50\u306f\u975e\u5e38\u306b\u6d3b\u6027\u3067\u3042\u308a\u3001\u4f4d\u7f6e4’\u3067\u30d2\u30c9\u30ed\u30ad\u30b7\u30eb\u307e\u305f\u306f\u30e1\u30c8\u30ad\u30b7\u30eb\u57fa\u3082\u7d30\u80de\u6bd2\u6027\u3067\u3059\u3002\u73fe\u5728\u3001\u3055\u307e\u3056\u307e\u306a\u764c\u306e\u6cbb\u7642\u306b\u304a\u3051\u308b\u4ed6\u306e\u7d30\u80de\u75c7\u306e\u7d44\u307f\u5408\u308f\u305b\u306b\u304a\u3051\u308b\u30ea\u30f3\u9178\u30b3\u30eb\u30bf\u30c1\u30c1\u30f3A-4\uff08CA-4-P\uff09\u306e\u7b2c3\u81e8\u5e8a\u671f\u306e\u691c\u67fb\uff08\u4f8b\uff1a\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\u3068\u306e\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\u306b\u3088\u308b\u672a\u5206\u5316\u7532\u72b6\u817a\u764c\u304c\u30ab\u30eb\u30dc\u30d7\u30e9\u30c1\u30f3\u3068\u6bd4\u8f03\u3057\u3066\u6bd4\u8f03\u3057\u3066 [\u521d\u3081] \uff09\u3002 Dark G.G.\u3001Hill S.A.\u3001Prize V.E.\u3001Tozer G.M.\u3001Pettit G.R.\u3001Chaplin D.J. \u300c\u816b\u760d\u8840\u7ba1\u7cfb\u306b\u5411\u3051\u3066\u5f37\u529b\u3067\u9078\u629e\u7684\u306a\u6bd2\u6027\u3092\u793a\u3059\u85ac\u5264\u3067\u3042\u308bCombretastatin A4\u3002\u300d Cancer Res 57\u3001str\u3002 1829\u20131834\u30011997\u3002 Galbraith SM\u3001Taylor NJ\u3001Lodge M\u3001Tozer GM\u3001Baddeley H\u3001Wilson I\u3001Prize VE\u3001Rustin GJS Combretastatin A4\u30ea\u30f3\u9178\u306f\u3001\u52d5\u7269\u304a\u3088\u3073\u30d2\u30c8\u816b\u760d\u306e\u8840\u7ba1\u7cfb\u3092\u6a19\u7684\u3068\u3057\u307e\u3059\u3002 Br J Cancer 83\uff081\uff09\uff1a12,2000\u3002 Grosios K\u3001Holwell SE\u3001McGown at\u3001Pettit GR\u3001Bibby MC In vivo\u304a\u3088\u3073in vitro\u8a55\u4fa1combretastatin A4\u304a\u3088\u3073\u305d\u306e\u30ea\u30f3\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u30d7\u30ed\u30c9\u30e9\u30c3\u30b0\u3002 Br J Cancer 81\uff1a1318\u20131327,1999\u3002 McGown A.T.\u3001Fox B.W.\u6297\u30df\u30c8\u30fc\u30b7\u30b9\u5264\u306e\u30b3\u30eb\u30d2\u30c1\u30f3\u3001combretastatin A4\u304a\u3088\u3073\u30a2\u30f3\u30d5\u30a7\u30c1\u30cb\u30fc\u30eb\u306e\u69cb\u9020\u7684\u304a\u3088\u3073\u751f\u5316\u5b66\u7684\u6bd4\u8f03\u3002\u6297\u304c\u3093\u85acDES 3\u3001str\u3002 249\u2013254\u30011989\u3002 \u30e2\u30f3\u30af\u3001\u30ad\u30fc\u30b9A;\u30b5\u30a4\u30ec\u3001\u30ed\u30b8\u30a7\u30ea\u30aa;\u30cf\u30c7\u30a3\u30de\u30cb\u3001\u30de\u30ea\u30ca\u30fc\u30c8b;\u30e0\u30ac\u30d9\u3001\u30d9\u30ce\u30f3E; et al\u3002\u30c1\u30e5\u30fc\u30d6\u30ea\u30f3\u30a2\u30bb\u30f3\u30d6\u30ea\u304a\u3088\u3073\u8840\u7ba1\u7834\u58ca\u5264\u30d0\u30a4\u30aa\u30aa\u30eb\u30b0\u306e\u963b\u5bb3\u5264\u3068\u3057\u3066\u306e\u30b3\u30f3\u30d6\u30ec\u30bf\u30b9\u30bf\u30c1\u30f3\u7a92\u7d20\u542b\u6709\u8a98\u5c0e\u4f53\u306e\u8a2d\u8a08\u3001\u5408\u6210\u3001\u304a\u3088\u3073\u751f\u7269\u5b66\u7684\u8a55\u4fa1\u3002\u533b\u85ac\u54c1\u3002 Chem\u300114\u30013231-3244\u30012006\u3002 \u30d1\u30c6\u30a3\u3001h; Taherbhai\u3001Z;\u30d5\u30a9\u30ec\u30b9\u30c8\u3001l;\u30a6\u30a3\u30c3\u30af\u30b9\u3001M;\u30d9\u30a4\u30ea\u30fc\u30ba;\u30b9\u30c6\u30fc\u30d7\u30eb\u3001a; et al\u3002\u30c8\u30e9\u30f3\u30b9\u30b3\u30f3\u30d6\u30ec\u30bf\u30b9\u30bf\u30c1\u30f3\u985e\u4f3c\u4f53\u306e\u8abf\u88fd\u306e\u305f\u3081\u306e\u7acb\u4f53\u7279\u7570\u7684\u7d4c\u8def\uff1a\u85ac\u7269\u8a2d\u8a08\u3068\u767a\u898b\u306b\u304a\u3051\u308b\u5408\u6210\u304a\u3088\u3073\u7d30\u80de\u6bd2\u6027\u6587\u5b57\u30012004\u30011\u3001275-278\u3002 Pettit G.R.\u3001Singh S.B.\u3001Niven M.L.\u3001Hamel E.\u3001Schmidt J.M. 119-31\u3001I-II 1987 Pettit G.R.\u3001Cragg G.M.\u3001Singh S.B. \u300c\u6297\u816b\u760d\u5264\u3001122\u3002combretum caffrum\u306e\u69cb\u6210\u8981\u7d20\u300d\u3002 Journal of Natural Products Tom 50\u3001Nr 3\u3001Str\u3002 386\u2013391\u3001V-VI1987\u3002DOI\uff1a10.1021\/NP50051A008\u3002 Pettit GR\u3001Singh SB\u3001Hamel E\u3001Lin CM\u3001Alberts DS\u3001Garia-Kendall D\u5f37\u529b\u306a\u7d30\u80de\u6210\u9577\u304a\u3088\u3073\u30c1\u30e5\u30fc\u30d6\u30ea\u30f3\u963b\u5bb3\u5264Combretastatin A4\u306e\u5206\u96e2\u3068\u69cb\u9020\u3002 Experientia 45\uff1a209\u2013211\u30011989\u3002 Pettit GR\u3001Temple C\u3001Narayanan VL\u3001Varma R\u3001Simpson MJ\u3001Boyd MR\u3001Rener GA\u3001Bansal N\u6297\u816b\u760d\u5264322. combletastatin A4\u30d7\u30ed\u30c7\u30e5\u30e9\u30b0\u306e\u5408\u6210\u3002\u6297\u304c\u3093\u85acDES 10\uff1a299\u2013309,1995\u3002 Stevenson JP\u3001Gallagher M\u3001Sun W\u3001Algazy K\u3001Vaughn DJ\u3001Haller DG\u3001Hiller K\u3001Halloran L\u3001O’Dwyer J\u30d5\u30a7\u30fc\u30baI\/Pharmackinetic\u8a66\u9a13\u5185\u76ae\u6bd2\u7d20Combretastatin A4P\uff08CA4P\uff09\u306ePharmackinetic\u8a66\u9a13\u3067\u306f\u3001\u6bce\u65e55\u65e5\u3054\u3068\u306bIV Bolus\u3068\u3057\u3066\u6295\u4e0e\u3055\u308c\u307e\u3059\u3002 Proc Am Assoc Cancer Res 41\uff1a54\u30012000\u3002 \u30c8\u30f3\u30d7\u30bd\u30f3M.\u30d6\u30ea\u30b9\u30c8\u30eb\u5927\u5b66\u5316\u5b66\u90e8\u306e\u30db\u30fc\u30e0\u30da\u30fc\u30b8\u3002\u30d6\u30ea\u30b9\u30c8\u30eb\u5927\u5b66\u3002 Publikacja 6 IX 2005 Kopia Z 20 IX 2006\u3002       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki47\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/all2jp\/wiki47\/archives\/15669#breadcrumbitem","name":"Comretableness-\u30a6\u30a3\u30ad\u30da\u30c7\u30a3\u30a2\u3001\u7121\u6599\u200b\u200b\u767e\u79d1\u4e8b\u5178"}}]}]