[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki19\/mhc-class-i-polypeptide-related-sequence-b\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki19\/mhc-class-i-polypeptide-related-sequence-b\/","headline":"MHC class I polypeptide\u2013related sequence B","name":"MHC class I polypeptide\u2013related sequence B","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens MHC class I polypeptide-related sequence B","datePublished":"2016-03-21","dateModified":"2016-03-21","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki19\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki19\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/4\/47\/PDB_1je6_EBI.jpg\/180px-PDB_1je6_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/4\/47\/PDB_1je6_EBI.jpg\/180px-PDB_1je6_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki19\/mhc-class-i-polypeptide-related-sequence-b\/","about":["Wiki"],"wordCount":5960,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensMHC class I polypeptide-related sequence B (MICB) is a protein that  is encoded by the MICB gene located within MHC locus.[5] MICB is related to MHC class I and has similar domain structure, which is made up of external \u03b11\u03b12\u03b13 domain, transmembrane segment and C-terminal cytoplasmic tail.[5] MICB is a stress-induced ligand for NKG2D receptor.[6] The heat shock stress pathway is involved in the regulation of MICB expression as transcription of MICB is regulated by promoter heat shock element.[7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4See also[edit]References[edit]^ a b c ENSG00000224378, ENSG00000206449, ENSG00000227772, ENSG00000238289, ENSG00000231372, ENSG00000234218, ENSG00000204516 GRCh38: Ensembl release 89: ENSG00000231179, ENSG00000224378, ENSG00000206449, ENSG00000227772, ENSG00000238289, ENSG00000231372, ENSG00000234218, ENSG00000204516 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000040987 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ a b Bahram S, Bresnahan M, Geraghty DE, Spies T (Jul 1994). “A second lineage of mammalian major histocompatibility complex class I genes”. Proceedings of the National Academy of Sciences of the United States of America. 91 (14): 6259\u201363. Bibcode:1994PNAS…91.6259B. doi:10.1073\/pnas.91.14.6259. PMC\u00a044180. PMID\u00a08022771.^ Bauer S, Groh V, Wu J, Steinle A, Phillips JH, Lanier LL, Spies T (Jul 1999). “Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA”. Science. 285 (5428): 727\u20139. doi:10.1126\/science.285.5428.727. PMID\u00a010426993.^ Groh V, Bahram S, Bauer S, Herman A, Beauchamp M, Spies T (Oct 1996). “Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium”. Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12445\u201350. Bibcode:1996PNAS…9312445G. doi:10.1073\/pnas.93.22.12445. PMC\u00a038011. PMID\u00a08901601.Further reading[edit]Braud VM, Allan DS, McMichael AJ (Feb 1999). “Functions of nonclassical MHC and non-MHC-encoded class I molecules”. Current Opinion in Immunology. 11 (1): 100\u20138. doi:10.1016\/S0952-7915(99)80018-1. PMID\u00a010047540.Borrego F, Kabat J, Kim DK, Lieto L, Maasho K, Pe\u00f1a J, Solana R, Coligan JE (Feb 2002). “Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells”. Molecular Immunology. 38 (9): 637\u201360. doi:10.1016\/S0161-5890(01)00107-9. PMID\u00a011858820.Leelayuwat C, Townend DC, Degli-Esposti MA, Abraham LJ, Dawkins RL (1994). “A new polymorphic and multicopy MHC gene family related to nonmammalian class I”. Immunogenetics. 40 (5): 339\u201351. doi:10.1007\/BF01246675. PMID\u00a07927538. S2CID\u00a010504768.Bahram S, Spies T (1996). “Nucleotide sequence of a human MHC class I MICB cDNA”. Immunogenetics. 43 (4): 230\u20133. doi:10.1007\/s002510050051. PMID\u00a08575823.Nalabolu SR, Shukla H, Nallur G, Parimoo S, Weissman SM (Jan 1996). “Genes in a 220-kb region spanning the TNF cluster in human MHC”. Genomics. 31 (2): 215\u201322. doi:10.1006\/geno.1996.0034. PMID\u00a08824804.Bonaldo MF, Lennon G, Soares MB (Sep 1996). “Normalization and subtraction: two approaches to facilitate gene discovery”. Genome Research. 6 (9): 791\u2013806. doi:10.1101\/gr.6.9.791. PMID\u00a08889548.Groh V, Bahram S, Bauer S, Herman A, Beauchamp M, Spies T (Oct 1996). “Cell stress-regulated human major histocompatibility complex class I gene expressed in gastrointestinal epithelium”. Proceedings of the National Academy of Sciences of the United States of America. 93 (22): 12445\u201350. Bibcode:1996PNAS…9312445G. doi:10.1073\/pnas.93.22.12445. PMC\u00a038011. PMID\u00a08901601.Bahram S, Shiina T, Oka A, Tamiya G, Inoko H (1997). “Genomic structure of the human MHC class I MICB gene”. Immunogenetics. 45 (2): 161\u20132. doi:10.1007\/s002510050184. PMID\u00a08952966. S2CID\u00a026270690.Gaudieri S, Leelayuwat C, Townend DC, Mullberg J, Cosman D, Dawkins RL (1997). “Allelic and interlocus comparison of the PERB11 multigene family in the MHC”. Immunogenetics. 45 (3): 209\u201316. doi:10.1007\/s002510050191. PMID\u00a08995188. S2CID\u00a06658841.Pellet P, Renaud M, Fodil N, Laloux L, Inoko H, Hauptmann G, Debr\u00e9 P, Bahram S, Theodorou I (1997). “Allelic repertoire of the human MICB gene”. Immunogenetics. 46 (5): 434\u20136. doi:10.1007\/s002510050299. PMID\u00a09271635. S2CID\u00a07799593.Ando H, Mizuki N, Ota M, Yamazaki M, Ohno S, Goto K, Miyata Y, Wakisaka K, Bahram S, Inoko H (1997). “Allelic variants of the human MHC class I chain-related B gene (MICB)”. Immunogenetics. 46 (6): 499\u2013508. doi:10.1007\/s002510050311. PMID\u00a09321430. S2CID\u00a01912407.Groh V, Steinle A, Bauer S, Spies T (Mar 1998). “Recognition of stress-induced MHC molecules by intestinal epithelial gammadelta T cells”. Science. 279 (5357): 1737\u201340. doi:10.1126\/science.279.5357.1737. PMID\u00a09497295.Visser CJ, Tilanus MG, Schaeffer V, Tatari Z, Tamouza R, Janin A, Charron D (Jun 1998). “Sequencing-based typing reveals six novel MHC class I chain-related gene B (MICB) alleles”. Tissue Antigens. 51 (6): 649\u201352. doi:10.1111\/j.1399-0039.1998.tb03008.x. PMID\u00a09694358.Steinle A, Groh V, Spies T (Oct 1998). “Diversification, expression, and gamma delta T cell recognition of evolutionarily distant members of the MIC family of major histocompatibility complex class I-related molecules”. Proceedings of the National Academy of Sciences of the United States of America. 95 (21): 12510\u20135. Bibcode:1998PNAS…9512510S. doi:10.1073\/pnas.95.21.12510. PMC\u00a022861. PMID\u00a09770516.Groh V, Rhinehart R, Secrist H, Bauer S, Grabstein KH, Spies T (Jun 1999). “Broad tumor-associated expression and recognition by tumor-derived gamma delta T cells of MICA and MICB”. Proceedings of the National Academy of Sciences of the United States of America. 96 (12): 6879\u201384. Bibcode:1999PNAS…96.6879G. doi:10.1073\/pnas.96.12.6879. PMC\u00a022010. PMID\u00a010359807.Tay GK, Hui J, Gaudieri S, Schmitt-Egenolf M, Martinez OP, Leelayuwat C, Williamson JF, Eiermann TH, Dawkins RL (Mar 2000). “PERB11 (MIC): a polymorphic MHC gene is expressed in skin and single nucleotide polymorphisms are associated with psoriasis”. Clinical and Experimental Immunology. 119 (3): 553\u20138. doi:10.1046\/j.1365-2249.2000.01140.x. PMC\u00a01905592. PMID\u00a010691930.Fischer G, P\u00e9rez-Rodr\u00edguez M, Arg\u00fcello JR, Cox ST, McWhinnie A, Travers PJ, Madrigal JA (Feb 2000). “Three novel MICB alleles”. Tissue Antigens. 55 (2): 166\u201370. doi:10.1034\/j.1399-0039.2000.550210.x. PMID\u00a010746790.Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL (Jun 2000). “Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice”. Immunity. 12 (6): 721\u20137. doi:10.1016\/S1074-7613(00)80222-8. PMID\u00a010894171.PDB gallery1je6: Structure of the MHC Class I Homolog MICB       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki19\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki19\/mhc-class-i-polypeptide-related-sequence-b\/#breadcrumbitem","name":"MHC class I polypeptide\u2013related sequence B"}}]}]