Parastoo Hashemi – Wikipedia

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Irani-British neural engineer

Parastoo (“Parry”) Hashemi (born 1980) is an Iranian-British neural engineer at Imperial College London and the University of South Carolina.

Hashemi’s research develops and applies sensors for brain measurements of neurotransmitters in the context of mental illness etiology, diagnosis and treatment.[1][2]

Life and academic career[edit]

Early life[edit]

Hashemi was born in Tehran, Iran and immigrated with her family to the United Kingdom, as a child, in 1986. She grew up in Durham, UK and attended Belmont Comprehensive school and Durham Johnston 6th Form College.

Hashemi graduated with a first class Master in Science (MSci) degree in chemistry from King’s College London in 2003.[2] She received her PhD in Bioengineering from Imperial College London in 2007 under the mentorship of Dr. Martyn Boutelle.[2][3] The focus of her Ph.D. research was to develop online microdialysis techniques for monitoring humans with traumatic brain injury.[2]

Hashemi moved to the United States in 2007 to perform her post-doctoral work with Dr. R. Mark Wightman at the University of North Carolina at Chapel Hill.[2][3] The focus of her post-doctoral research was to develop a selective method for in vivo detection for brain serotonin.[2]

Positions held[edit]

Hashemi held an assistant professorship in the department of Chemistry at Wayne State University[2] from 2011 to 2015 and was tenured in the department of Chemistry and Biochemistry at the University of South Carolina in 2017. Hashemi continues to run her lab at the University of South Carolina[2] and holds a senior lecturer position in the Department of Bioengineering at Imperial College London[4] since 2019.

Research[edit]

Hashemi has pioneered tools for measurements of serotonin in the brain,[2][5][6][7] a neurotransmitter important in the pathology of depression. Her team is using these tools in a variety of models to better understand, diagnose and treat mental disorders, with a focus on depression.[8]

Notable awards[edit]

  • 2019 CAMS Fellow (Community for Analytical Measurement Science)
  • 2018 Society for Electroanalytical Chemistry (SEAC) Royce W. Murray Award[9]
  • 2018 Society of Pittsburgh Chemists Pittcon Achievement Award[10]
  • 2018 USC Breakthrough Stars Award[11]
  • 2017 Midwestern Universities Analytical Chemistry Conference Young Investigator Travel Award
  • 2017 International Society for Neurochemistry Brain in Flux Symposium Young Faculty Travel Award
  • 2017 NSF CAREER Award[12]
  • 2015 Eli Lilly Young Investigator Award in Analytical Chemistry
  • 2013 Masao Horiba Award for Analytical Chemistry[13]

Notable papers[edit]

References[edit]

  1. ^ “Parastoo Hashemi: Tackling Complex Biological and Environmental Problems”. 2 March 2017.
  2. ^ a b c d e f g h i “CV of Parastoo Hashemi” (PDF).{{cite web}}: CS1 maint: url-status (link)
  3. ^ a b “Chemistry Tree – Parastoo Hashemi Family Tree”.
  4. ^ “Academic staff and research fellows | Faculty of Engineering | Imperial College London”.
  5. ^ Wood, Kevin M.; Zeqja, Anisa; Nijhout, H. Frederik; Reed, Michael C.; Best, Janet; Hashemi, Parastoo (2014). “Voltammetric and mathematical evidence for dual transport mediation of serotonin clearance in vivo”. Journal of Neurochemistry. 130 (3): 351–359. doi:10.1111/jnc.12733. ISSN 1471-4159. PMC 4107184. PMID 24702305.
  6. ^ Abdalla, Aya; Atcherley, Christopher W.; Pathirathna, Pavithra; Samaranayake, Srimal; Qiang, Beidi; Peña, Edsel; Morgan, Stephen L.; Heien, Michael L.; Hashemi, Parastoo (2017-09-07). “In Vivo Ambient Serotonin Measurements at Carbon-Fiber Microelectrodes”. Analytical Chemistry. 89 (18): 9703–9711. doi:10.1021/acs.analchem.7b01257. ISSN 0003-2700. PMC 5837047. PMID 28795565.
  7. ^ Saylor, Rachel A.; Hersey, Melinda; West, Alyssa; Buchanan, Anna Marie; Berger, Shane N.; Nijhout, H. Frederik; Reed, Michael C.; Best, Janet; Hashemi, Parastoo (2019). “In vivo Hippocampal Serotonin Dynamics in Male and Female Mice: Determining Effects of Acute Escitalopram Using Fast Scan Cyclic Voltammetry”. Frontiers in Neuroscience. 13: 362. doi:10.3389/fnins.2019.00362. ISSN 1662-453X. PMC 6499219. PMID 31110471.
  8. ^ Hersey, Melinda; Samaranayake, Srimal; Berger, Shane N.; Tavakoli, Navid; Mena, Sergio; Nijhout, H. Frederik; Reed, Michael C.; Best, Janet; Blakely, Randy D.; Reagan, Lawrence P.; Hashemi, Parastoo (2021-07-28). “Inflammation-Induced Histamine Impairs the Capacity of Escitalopram to Increase Hippocampal Extracellular Serotonin”. Journal of Neuroscience. 41 (30): 6564–6577. doi:10.1523/JNEUROSCI.2618-20.2021. ISSN 0270-6474. PMC 8318079. PMID 34083254.
  9. ^ “Awards Information – Charles N. Reilley, Y.I., and Travel”.
  10. ^ “Pittcon Announces 2018 Award Recipients for Outstanding Achievements in Analytical Chemistry and Applied Spectroscopy”. 2 October 2017.
  11. ^ “2018 Breakthrough Awards Cover the Academic Spectrum – Office of the Vice President for Research | University of South Carolina”.
  12. ^ “NSF Award Search: Award#1654111 – CAREER: The fundamental principles of modified carbon fiber microelectrodes as speciation sensors”.
  13. ^ “2013 | Masao Horiba Awards / 堀場雅夫賞”.

External links[edit]