[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki2\/warthins-tumor-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki2\/warthins-tumor-wikipedia\/","headline":"Warthin’s tumor – Wikipedia","name":"Warthin’s tumor – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Medical condition Warthin’s tumor Other names Warthin tumour, monomorphic adenoma, adenolymphoma Cytopathology of","datePublished":"2016-03-08","dateModified":"2016-03-08","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki2\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki2\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/e\/e7\/Cytopathology_of_Warthin%27s_tumor.jpg\/300px-Cytopathology_of_Warthin%27s_tumor.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/e\/e7\/Cytopathology_of_Warthin%27s_tumor.jpg\/300px-Cytopathology_of_Warthin%27s_tumor.jpg","height":"212","width":"300"},"url":"https:\/\/wiki.edu.vn\/en\/wiki2\/warthins-tumor-wikipedia\/","wordCount":3451,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Medical conditionWarthin’s tumorOther namesWarthin tumour, monomorphic adenoma, adenolymphomaCytopathology of Warthin’s tumor, with typical cellular features (and a relatively uncommon binucleated cell).[1]Pap stain.SpecialtyOncology\u00a0Warthin’s tumor, also known as papillary cystadenoma lymphomatosum, is a benign cystic tumor of the salivary glands containing abundant lymphocytes and germinal centers (lymph node-like stroma). It is named for pathologist Aldred Scott Warthin, who described two cases in 1929.[2]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Table of ContentsSigns and symptoms[edit]Locations[edit]Diagnosis[edit]Treatment[edit]See also[edit]References[edit]Additional sources[edit]External links[edit]Signs and symptoms[edit]Warthin’s tumor primarily affects older individuals (age 60\u201370 years). There is a slight male predilection according to recent studies. The tumor is slow growing, painless, and usually appears in the tail of the parotid gland near the angle of the mandible. In 5\u201314% of cases, Warthin’s tumor is bilateral, but the two masses usually are at different times. Warthin’s tumor is highly unlikely to become malignant.[citation needed]Locations[edit]         (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Relative incidence of parotid tumors, with Warthin’s tumor near top right.[3]The gland most likely affected is the parotid gland. In fact, it is the only tumor virtually restricted to the parotid gland. Warthin’s tumor is the second most common benign parotid tumor after pleomorphic adenoma, but its prevalence is steadily increasing.[4]Its cause is unknown, but there is a strong association with cigarette smoking.  Smokers are at 8 times greater risk of developing Warthin’s tumor than the general population.[5]Diagnosis[edit]The appearance of this tumor under the microscope is unique. There are cystic spaces surrounded by two uniform rows of oncocytes, which are epithelial cells with abundant, granular, eosinophilic cytoplasm.[6] The cystic spaces have epithelium referred to as papillary infoldings that protrude into them.  Additionally, the epithelium has lymphoid stroma with germinal center formation.[citation needed]The differential diagnosis includes sebaceous lymphadenoma and oncocytoma.This Warthin’s tumor presented as a parotid mass in a middle-aged male, who underwent superficial parotidectomy. The tumor, at the right of the image, is well-demarcated from the adjacent parotid tissue and tends to shell out from it.Low magnification micrograph of a Warthin tumor arising from the parotid gland.Histopathology of Warthin tumor in the parotid gland. H&E stain.Histopathology of Warthin tumor in the parotid gland. Another view of a file “Warthin tumor (1).jpg”. H&E stain.Histopathology of Warthin tumor in the parotid gland. Higher magnification of a file “Warthin tumor (1).jpg”. H&E stain.Intermediate magnification micrograph of a Warthin tumor.High magnification micrograph of a Warthin tumor showing the characteristic bilayered epithelium.Treatment[edit]Most of these tumors are treated with surgical removal called parotidectomy. Contrary to pleomorphic adenoma, it is non recurrent.See also[edit]References[edit]^ Image by Mikael H\u00e4ggstr\u00f6m, MD. References for entries:– K\u00f6yba\u015fio\u011flu FF, \u00d6nal B, Han \u00dc, Adaba\u011f A, \u015eahpaz A (2020). “Cytomorphological findings in diagnosis of Warthin tumor”. Turk J Med Sci. 50 (1): 148\u2013154. doi:10.3906\/sag-1901-215. PMC\u00a07080357. PMID\u00a031769640.{{cite journal}}:  CS1 maint: multiple names: authors list (link)Binucleation:– Dr.S. Malliga (2006-10-18). “A correlative cytological and histopathological study on lesions of salivary gland” (PDF).– Chan MKM, McGuire LJ: Cytodiagnosis of Lesions Presenting as Salivary Gland Swellings: A Report of Seven Cases. Diagn Cytopathol 8: 439-443, 1992b.^ Witt RL, ed. (2005). “Chapter 9 “Benign tumors, cysts, and tumor-like conditions of the salivary glands”. Salivary Gland Diseases: Surgical and Medical Management. New York: Thieme Medical Publishers. p.\u00a0123. ISBN\u00a01-58890-414-8.^ Steve C Lee, MD, PhD (22 December 2022). “Salivary Gland Neoplasms”. Medscape.{{cite journal}}:  CS1 maint: multiple names: authors list (link) Updated: Jan 13, 2021Diagrams by Mikael H\u00e4ggstr\u00f6m, MD^ Psychogios G, Vlastos I, Th\u00f6lken R, Zenk J (July 2020). “Warthin’s tumour seems to be the most common benign neoplasm of the parotid gland in Germany”. European Archives of Oto-Rhino-Laryngology. 277 (7): 2081\u20132084. doi:10.1007\/s00405-020-05894-z. PMID\u00a032189070. S2CID\u00a0212940703.^ Kumar V, Abbas AK, Fausto N (2005). Robbins and Cotran pathologic basis of disease (7th\u00a0ed.). St. Louis, MO: Elsevier Saunders. ISBN\u00a00-7216-0187-1.^ Chakrabarti I, Basu A, Ghosh N (2012). “Oncocytic lesion of parotid gland: A dilemma for cytopathologists”. J Cytol. 29 (1): 80\u20132. doi:10.4103\/0970-9371.93236. PMC\u00a03307464. PMID\u00a022438628.{{cite journal}}:  CS1 maint: multiple names: authors list (link)Additional sources[edit]Kahn, Michael A. Basic Oral and Maxillofacial Pathology. Volume 1. 2001.External links[edit]     (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki2\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki2\/warthins-tumor-wikipedia\/#breadcrumbitem","name":"Warthin’s tumor – Wikipedia"}}]}]