[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/2020\/06\/24\/dynll2-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/2020\/06\/24\/dynll2-wikipedia\/","headline":"DYNLL2 – Wikipedia","name":"DYNLL2 – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens Dynein light chain 2, cytoplasmic is a protein","datePublished":"2020-06-24","dateModified":"2020-06-24","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/3\/30\/PDB_1cmi_EBI.jpg\/180px-PDB_1cmi_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/3\/30\/PDB_1cmi_EBI.jpg\/180px-PDB_1cmi_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/2020\/06\/24\/dynll2-wikipedia\/","about":["Wiki"],"wordCount":6063,"articleBody":"From Wikipedia, the free encyclopedia  Protein-coding gene in the species Homo sapiensDynein light chain 2, cytoplasmic is a protein that in humans is encoded by the DYNLL2 gene.[5][6]  Table of ContentsInteractions[edit]References[edit]Further reading[edit]External links[edit]Interactions[edit]DYNLL2 has been shown to interact with DLG4,[7]C12orf40,[8]DLGAP1,[7]MYO5A[7][9] and BMF.[9][10]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000264364 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020483 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Pfister KK, Fisher EM, Gibbons IR, Hays TS, Holzbaur EL, McIntosh JR, Porter ME, Schroer TA, Vaughan KT, Witman GB, King SM, Vallee RB (November 2005). “Cytoplasmic dynein nomenclature”. J Cell Biol. 171 (3): 411\u20133. doi:10.1083\/jcb.200508078. PMC\u00a02171247. PMID\u00a016260502.^ “Entrez Gene: DYNLL2 dynein, light chain, LC8-type 2”.^ a b c Naisbitt, S; Valtschanoff J; Allison D W; Sala C; Kim E; Craig A M; Weinberg R J; Sheng M (June 2000). “Interaction of the postsynaptic density-95\/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein”. J. Neurosci. UNITED STATES. 20 (12): 4524\u201334. doi:10.1523\/JNEUROSCI.20-12-04524.2000. ISSN\u00a00270-6474. PMC\u00a06772433. PMID\u00a010844022.^ Rolland, Thomas; Ta\u015fan, Murat; Charloteaux, Benoit; Pevzner, Samuel J.; Zhong, Quan; Sahni, Nidhi; Yi, Song; Lemmens, Irma; Fontanillo, Celia; Mosca, Roberto; Kamburov, Atanas; Ghiassian, Susan D.; Yang, Xinping; Ghamsari, Lila; Balcha, Dawit; Begg, Bridget E.; Braun, Pascal; Brehme, Marc; Broly, Martin P.; Carvunis, Anne-Ruxandra; Convery-Zupan, Dan; Corominas, Roser; Coulombe-Huntington, Jasmin; Dann, Elizabeth; Dreze, Matija; Dricot, Am\u00e9lie; Fan, Changyu; Franzosa, Eric; Gebreab, Fana; Gutierrez, Bryan J.; Hardy, Madeleine F.; Jin, Mike; Kang, Shuli; Kiros, Ruth; Lin, Guan Ning; Luck, Katja; MacWilliams, Andrew; Menche, J\u00f6rg; Murray, Ryan R.; Palagi, Alexandre; Poulin, Matthew M.; Rambout, Xavier; Rasla, John; Reichert, Patrick; Romero, Viviana; Ruyssinck, Elien; Sahalie, Julie M.; Scholz, Annemarie; Shah, Akash A.; Sharma, Amitabh; Shen, Yun; Spirohn, Kerstin; Tam, Stanley; Tejeda, Alexander O.; Trigg, Shelly A.; Twizere, Jean-Claude; Vega, Kerwin; Walsh, Jennifer; Cusick, Michael E.; Xia, Yu; Barab\u00e1si, Albert-L\u00e1szl\u00f3; Iakoucheva, Lilia M.; Aloy, Patrick; De Las Rivas, Javier; Tavernier, Jan; Calderwood, Michael A.; Hill, David E.; Hao, Tong; Roth, Frederick P.; Vidal, Marc (November 2014). “A Proteome-Scale Map of the Human Interactome Network”. Cell. 159 (5): 1212\u20131226. doi:10.1016\/j.cell.2014.10.050. PMC\u00a04266588. PMID\u00a025416956.^ a b Puthalakath, H; Villunger A; O’Reilly L A; Beaumont J G; Coultas L; Cheney R E; Huang D C; Strasser A (September 2001). “Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis”. Science. United States. 293 (5536): 1829\u201332. Bibcode:2001Sci…293.1829P. doi:10.1126\/science.1062257. ISSN\u00a00036-8075. PMID\u00a011546872. S2CID\u00a05638023.^ Day, Catherine L; Puthalakath Hamsa; Skea Gretchen; Strasser Andreas; Barsukov Igor; Lian Lu-Yun; Huang David C S; Hinds Mark G (February 2004). “Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands”. Biochem. J. England. 377 (Pt 3): 597\u2013605. doi:10.1042\/BJ20031251. PMC\u00a01223895. PMID\u00a014561217.Further reading[edit]Naisbitt S, Valtschanoff J, Allison DW,  et\u00a0al. (2000). “Interaction of the postsynaptic density-95\/guanylate kinase domain-associated protein complex with a light chain of myosin-V and dynein”. J. Neurosci. 20 (12): 4524\u201334. doi:10.1523\/JNEUROSCI.20-12-04524.2000. PMC\u00a06772433. PMID\u00a010844022.Haraguchi K, Satoh K, Yanai H,  et\u00a0al. (2001). “The hDLG-associated protein DAP interacts with dynein light chain and neuronal nitric oxide synthase”. Genes Cells. 5 (11): 905\u2013911. doi:10.1046\/j.1365-2443.2000.00374.x. PMID\u00a011122378. S2CID\u00a037107139.Puthalakath H, Villunger A, O’Reilly LA,  et\u00a0al. (2001). “Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis”. Science. 293 (5536): 1829\u201332. Bibcode:2001Sci…293.1829P. doi:10.1126\/science.1062257. PMID\u00a011546872. S2CID\u00a05638023.Fuhrmann JC, Kins S, Rostaing P,  et\u00a0al. (2002). “Gephyrin interacts with Dynein light chains 1 and 2, components of motor protein complexes”. J. Neurosci. 22 (13): 5393\u2013402. doi:10.1523\/JNEUROSCI.22-13-05393.2002. PMC\u00a06758200. PMID\u00a012097491.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Day CL, Puthalakath H, Skea G,  et\u00a0al. (2004). “Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands”. Biochem. J. 377 (Pt 3): 597\u2013605. doi:10.1042\/BJ20031251. PMC\u00a01223895. PMID\u00a014561217.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.Rual JF, Venkatesan K, Hao T,  et\u00a0al. (2005). “Towards a proteome-scale map of the human protein-protein interaction network”. Nature. 437 (7062): 1173\u20138. Bibcode:2005Natur.437.1173R. doi:10.1038\/nature04209. PMID\u00a016189514. S2CID\u00a04427026.External links[edit]Overview of all the structural information available in the PDB for UniProt: Q96FJ2 (Dynein light chain 2, cytoplasmic) at the PDBe-KB.PDB gallery  1cmi: STRUCTURE OF THE HUMAN PIN\/LC8 DIMER WITH A BOUND PEPTIDE1f3c: REFINED SOLUTION STRUCTURE OF 8KDA DYNEIN LIGHT CHAIN (DLC8)1f95: SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND BIM PEPTIDE COMPLEX1f96: SOLUTION STRUCTURE OF DYNEIN LIGHT CHAIN 8 (DLC8) AND NNOS PEPTIDE COMPLEX1pwj: Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly1pwk: Structure of the Monomeric 8-kDa Dynein Light Chain and Mechanism of Domain Swapped Dimer Assembly1re6: Localisation of Dynein Light Chains 1 and 2 and their Pro-apoptotic Ligands1rhw: The solution structure of the pH-induced monomer of dynein light chain LC8 from Drosophila2pg1: Structural analysis of a cytoplasmic dynein Light Chain-Intermediate Chain complex  "},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/2020\/06\/24\/dynll2-wikipedia\/#breadcrumbitem","name":"DYNLL2 – Wikipedia"}}]}]