[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/cox7a1-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/cox7a1-wikipedia\/","headline":"COX7A1 – Wikipedia","name":"COX7A1 – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens Cytochrome c oxidase polypeptide 7A1, mitochondrial is an","datePublished":"2021-02-10","dateModified":"2021-02-10","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/cox7a1-wikipedia\/","about":["Wiki"],"wordCount":3285,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensCytochrome c oxidase polypeptide 7A1, mitochondrial is an enzyme that in humans is encoded by the COX7A1 gene.[5][6][7]Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues. Other polypeptides of subunit VIIa are present in both muscle and nonmuscle tissues, and are encoded by different genes.[7]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000161281 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000074218 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Arnaudo E, Hirano M, Seelan RS, Milatovich A, Hsieh CL, Fabrizi GM, Grossman LI, Francke U, Schon EA (Nov 1992). “Tissue-specific expression and chromosome assignment of genes specifying two isoforms of subunit VIIa of human cytochrome c oxidase”. Gene. 119 (2): 299\u2013305. doi:10.1016\/0378-1119(92)90287-Y. PMID\u00a01327965.^ Fabrizi GM, Rizzuto R, Nakase H, Mita S, Lomax MI, Grossman LI, Schon EA (Oct 1989). “Sequence of a cDNA specifying subunit VIIa of human cytochrome c oxidase”. Nucleic Acids Res. 17 (17): 7107. doi:10.1093\/nar\/17.17.7107. PMC\u00a0318441. PMID\u00a02550906.^ a b “Entrez Gene: COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)”.External links[edit]Further reading[edit]Lenka N, Vijayasarathy C, Mullick J, Avadhani NG (1998). “Structural organization and transcription regulation of nuclear genes encoding the mammalian cytochrome c oxidase complex”. Prog. Nucleic Acid Res. Mol. Biol. Progress in Nucleic Acid Research and Molecular Biology. 61: 309\u2013344. doi:10.1016\/S0079-6603(08)60830-2. ISBN\u00a0978-0-12-540061-9. PMID\u00a09752724.Van Kuilenburg AB, Van Beeumen JJ, Van der Meer NM, Muijsers AO (1992). “Subunits VIIa,b,c of human cytochrome c oxidase. Identification of both ‘heart-type’ and ‘liver-type’ isoforms of subunit VIIa in human heart”. Eur. J. Biochem. 203 (1\u20132): 193\u2013199. doi:10.1111\/j.1432-1033.1992.tb19847.x. PMID\u00a01309697.Wolz W, Kress W, Mueller CR (1998). “Genomic sequence and organization of the human gene for cytochrome c oxidase subunit (COX7A1) VIIa-M”. Genomics. 45 (2): 438\u2013442. doi:10.1006\/geno.1997.4937. PMID\u00a09344674.Schmidt TR, Goodman M, Grossman LI (1999). “Molecular evolution of the COX7A gene family in primates”. Mol. Biol. Evol. 16 (5): 619\u201326. doi:10.1093\/oxfordjournals.molbev.a026144. PMID\u00a010335655.Yu M, Jaradat SA, Grossman LI (2002). “Genomic organization and promoter regulation of human cytochrome c oxidase subunit VII heart\/muscle isoform (COX7AH)”. Biochim. Biophys. Acta. 1574 (3): 345\u201353. doi:10.1016\/s0167-4781(02)00228-2. PMID\u00a011997101.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u201316903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Grimwood J, Gordon LA, Olsen A,  et\u00a0al. (2004). “The DNA sequence and biology of human chromosome 19”. Nature. 428 (6982): 529\u2013535. Bibcode:2004Natur.428..529G. doi:10.1038\/nature02399. PMID\u00a015057824.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20132127. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.  "},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/cox7a1-wikipedia\/#breadcrumbitem","name":"COX7A1 – Wikipedia"}}]}]