[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/actinidain-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/actinidain-wikipedia\/","headline":"Actinidain – Wikipedia","name":"Actinidain – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Class of enzymes Actinidain (EC 3.4.22.14, actinidin, Actinidia anionic protease, proteinase A2 of","datePublished":"2014-11-19","dateModified":"2014-11-19","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/actinidain-wikipedia\/","wordCount":2742,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Class of enzymesActinidain (EC 3.4.22.14, actinidin, Actinidia anionic protease, proteinase A2 of Actinidia chinensis) is a type of cysteine protease enzyme found in fruits including kiwifruit (genus Actinidia), pineapple, mango, banana, figs, and papaya. This enzyme is part of the peptidase C1 family of papain-like proteases.[1][2][3][4]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4As a known allergen in kiwifruit,[5] the enzyme is under preliminary research for its effect on tight junction proteins of intestinal epithelial cells.[6][7]Actinidain is commercially useful as a meat tenderiser[8][9] and in coagulating milk for dairy products.[10] The denaturation temperature of actinidain is 60\u00a0\u00b0C (140\u00a0\u00b0F), lower than that of similar meat tenderising enzymes bromelain from pineapple and papain from papaya.[11]References[edit]^ Baker EN, Boland MJ, Calder PC, Hardman MJ (November 1980). “The specificity of actinidin and its relationship to the structure of the enzyme”. Biochimica et Biophysica Acta (BBA) – Enzymology. 616 (1): 30\u20134. doi:10.1016\/0005-2744(80)90260-0. PMID\u00a07002215.^ Kamphuis IG, Drenth J, Baker EN (March 1985). “Thiol proteases. Comparative studies based on the high-resolution structures of papain and actinidin, and on amino acid sequence information for cathepsins B and H, and stem bromelain”. Journal of Molecular Biology. 182 (2): 317\u201329. doi:10.1016\/0022-2836(85)90348-1. PMID\u00a03889350.^ Baker EN, Drenth J (1987). “The thiol proteases: structure and mechanism”.  In Jurnak FA, McPherson A (eds.). Active Sites of Enzymes. Biological Macromolecules and Assemblies. Vol.\u00a03. New York: John Wiley and Sons. pp.\u00a0314\u2013368. ISBN\u00a0978-0-471-85142-4.^ Gul S, Mellor GW, Thomas EW, Brocklehurst K (May 2006). “Temperature-dependences of the kinetics of reactions of papain and actinidin with a series of reactivity probes differing in key molecular recognition features”. The Biochemical Journal. 396 (1): 17\u201321. doi:10.1042\/BJ20051501. PMC\u00a01449998. PMID\u00a016445383.^ Maddumage R, Nieuwenhuizen NJ, Bulley SM, Cooney JM, Green SA, Atkinson RG (January 2013). “Diversity and relative levels of actinidin, kiwellin, and thaumatin-like allergens in 15 varieties of kiwifruit (Actinidia)”. Journal of Agricultural and Food Chemistry. 61 (3): 728\u201339. doi:10.1021\/jf304289f. PMID\u00a023289429.^ Grozdanovic MM, \u010cavi\u0107 M, Ne\u0161i\u0107 A, Andjelkovi\u0107 U, Akbari P, Smit JJ, Gavrovi\u0107-Jankulovi\u0107 M (March 2016). “Kiwifruit cysteine protease actinidin compromises the intestinal barrier by disrupting tight junctions”. Biochimica et Biophysica Acta (BBA) – General Subjects. 1860 (3): 516\u201326. doi:10.1016\/j.bbagen.2015.12.005. PMID\u00a026701113.^ Cavic M, Grozdanovic MM, Bajic A, Jankovic R, Andjus PR, Gavrovic-Jankulovic M (October 2014). “The effect of kiwifruit (Actinidia deliciosa) cysteine protease actinidin on the occludin tight junction network in T84 intestinal epithelial cells”. Food and Chemical Toxicology. 72: 61\u20138. doi:10.1016\/j.fct.2014.07.012. PMID\u00a025042511.^ Bekhit AA, Hopkins DL, Geesink G, Bekhit AA, Franks P (2014). “Exogenous proteases for meat tenderization”. Critical Reviews in Food Science and Nutrition. 54 (8): 1012\u201331. doi:10.1080\/10408398.2011.623247. PMID\u00a024499119. S2CID\u00a057554.^ Eshamah H, Han I, Naas H, Acton J, Dawson P (April 2014). “Antibacterial effects of natural tenderizing enzymes on different strains of Escherichia coli O157:H7 and Listeria monocytogenes on beef”. Meat Science. 96 (4): 1494\u2013500. doi:10.1016\/j.meatsci.2013.12.010. PMID\u00a024447905.^ Katsaros GI, Tavantzis G, Taoukis PS (January 2010). “Production of novel dairy products using actinidin and high pressure as enzyme activity regulator”. Innovative Food Science & Emerging Technologies. 11 (1): 47\u201351. doi:10.1016\/j.ifset.2009.08.007.^ Tart\u00e9 R (2008). Ingredients in meat products properties, functionality and applications. New York: Springer. ISBN\u00a0978-0-387-71327-4.External links[edit]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/actinidain-wikipedia\/#breadcrumbitem","name":"Actinidain – Wikipedia"}}]}]