[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/actr3b-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/actr3b-wikipedia\/","headline":"ACTR3B – Wikipedia","name":"ACTR3B – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Gene of the species Homo sapiens Actin-related protein 3B also known as ARP3-beta","datePublished":"2015-09-03","dateModified":"2015-09-03","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/c\/ca\/PDB_1k8k_EBI.jpg\/180px-PDB_1k8k_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/c\/ca\/PDB_1k8k_EBI.jpg\/180px-PDB_1k8k_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/actr3b-wikipedia\/","wordCount":2950,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Gene of the species Homo sapiensActin-related protein 3B also known as ARP3-beta is a protein that in humans is encoded by the ACTR3B gene.[4] Pseudogenes of this gene are located on chromosomes 2, 4, 10, 16, 22 and Y. Alternative splicing results in multiple transcript variants and protein isoforms.[4]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Table of ContentsFunction[edit]References[edit]External links[edit]Further reading[edit]Function[edit]This gene encodes a member of the actin-related proteins (ARP), which form multiprotein complexes and share 35-55% amino acid identity with conventional actin. The protein encoded by this gene may have a regulatory role in the actin cytoskeleton and induce cell-shape change and motility.[4]References[edit]External links[edit]Further reading[edit]Machesky LM, Gould KL (Feb 1999). “The Arp2\/3 complex: a multifunctional actin organizer”. Current Opinion in Cell Biology. 11 (1): 117\u201321. doi:10.1016\/S0955-0674(99)80014-3. PMID\u00a010047519.Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O’Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). “Large-scale mapping of human protein-protein interactions by mass spectrometry”. Molecular Systems Biology. 3 (1): 89. doi:10.1038\/msb4100134. PMC\u00a01847948. PMID\u00a017353931.Shindo-Okada N, Iigo M (Dec 2003). “Expression of the Arp11 gene suppresses the tumorigenicity of PC-14 human lung adenocarcinoma cells”. Biochemical and Biophysical Research Communications. 312 (4): 889\u201396. doi:10.1016\/j.bbrc.2003.10.200. PMID\u00a014651955.Shindo-Okada N, Shimizu K (Jan 2001). “Isolation of a novel actin-related gene expressed in low-metastatic PC-14 human lung adenocarcinoma”. Biochemical and Biophysical Research Communications. 280 (1): 61\u20137. doi:10.1006\/bbrc.2000.4059. PMID\u00a011162478.Jay P, Berg\u00e9-Lefranc JL, Massacrier A, Roessler E, Wallis D, Muenke M, Gastaldi M, Taviaux S, Cau P, Berta P (May 2000). “ARP3beta, the gene encoding a new human actin-related protein, is alternatively spliced and predominantly expressed in brain neuronal cells”. European Journal of Biochemistry. 267 (10): 2921\u20138. doi:10.1046\/j.1432-1327.2000.01306.x. PMID\u00a010806390.PDB gallery       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x41k8k: Crystal Structure of Arp2\/3 Complex1tyq: Crystal structure of Arp2\/3 complex with bound ATP and calcium1u2v: Crystal structure of Arp2\/3 complex with bound ADP and calcium2p9i: Crystal Structure of bovine Arp2\/3 Complex co-crystallized with ADP and crosslinked with gluteraldehyde2p9k: Crystal structure of bovine Arp2\/3 complex co-crystallized with ATP and crosslinked with glutaraldehyde2p9l: Crystal Structure of bovine Arp2\/3 complex2p9n: Crystal Structure of bovine Arp2\/3 complex co-crystallized with ADP2p9p: Crystal Structure of bovine Arp2\/3 complex co-crystallized with ADP2p9s: Structure of bovine Arp2\/3 complex co-crystallized with ATP\/Mg2+2p9u: Crystal structure of bovine Arp2\/3 complex co-crystallized with AMP-PNP and calciumThis article incorporates text from the United States National Library of Medicine, which is in the public domain.       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