[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/acyl-homoserine-lactone-synthase-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/acyl-homoserine-lactone-synthase-wikipedia\/","headline":"Acyl-homoserine-lactone synthase – Wikipedia","name":"Acyl-homoserine-lactone synthase – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Class of enzymes Acyl-homoserine-lactone synthase (EC 2.3.1.184) is an enzyme with systematic name","datePublished":"2021-06-15","dateModified":"2021-06-15","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/wikimedia.org\/api\/rest_v1\/media\/math\/render\/svg\/1c37b981df851b9e54e489e017b1481e37d418f3","url":"https:\/\/wikimedia.org\/api\/rest_v1\/media\/math\/render\/svg\/1c37b981df851b9e54e489e017b1481e37d418f3","height":"","width":""},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/acyl-homoserine-lactone-synthase-wikipedia\/","about":["Wiki"],"wordCount":2719,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Class of enzymesAcyl-homoserine-lactone synthase (EC 2.3.1.184) is an enzyme with systematic name acyl-(acyl-carrier protein):S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing).[1][2][3][4][5][6][7][8][9] This enzyme catalyses the following chemical reaction       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4acyl-[acyl-carrier protein] + S-adenosyl-L-methionine \u21cc{displaystyle rightleftharpoons } [acyl-carrier protein] + S-methyl-5′-thioadenosine + N-acyl-L-homoserine lactoneAcyl-homoserine lactones (AHLs) are produced by a number of bacterial species and are used by them to regulate the expression of virulence genes in a process known as quorum-sensing.Alternate names[edit]acyl-homoserine lactone synthase, acyl homoserine lactone synthase, acyl-homoserinelactone synthase, acylhomoserine lactone synthase, AHL synthase, AHS, AHSL synthase, AhyI, AinS, AinS protein, autoinducer synthase, autoinducer synthesis protein rhlI, EsaI, ExpISCC1, ExpISCC3065, LasI, LasR, LuxI, LuxI protein, LuxM, N-acyl homoserine lactone synthase, RhlI, YspI, acyl-[acyl carrier protein]:S-adenosyl-L-methionine acyltranserase (lactone-forming, methylthioadenosine-releasing)References[edit]^ Schaefer AL, Val DL, Hanzelka BL, Cronan JE, Greenberg EP (September 1996). “Generation of cell-to-cell signals in quorum sensing: acyl homoserine lactone synthase activity of a purified Vibrio fischeri LuxI protein”. Proceedings of the National Academy of Sciences of the United States of America. 93 (18): 9505\u20139. doi:10.1073\/pnas.93.18.9505. PMC\u00a038458. PMID\u00a08790360.^ Watson WT, Murphy FV, Gould TA, Jambeck P, Val DL, Cronan JE, Beck von Bodman S, Churchill ME (December 2001). “Crystallization and rhenium MAD phasing of the acyl-homoserinelactone synthase EsaI”. Acta Crystallographica D. 57 (Pt 12): 1945\u20139. doi:10.1107\/s0907444901014512. PMID\u00a011717525.^ Chakrabarti S, Sowdhamini R (April 2003). “Functional sites and evolutionary connections of acylhomoserine lactone synthases”. Protein Engineering. 16 (4): 271\u20138. doi:10.1093\/proeng\/gzg031. PMID\u00a012736370.^ Hanzelka BL, Parsek MR, Val DL, Dunlap PV, Cronan JE, Greenberg EP (September 1999). “Acylhomoserine lactone synthase activity of the Vibrio fischeri AinS protein”. Journal of Bacteriology. 181 (18): 5766\u201370. doi:10.1128\/JB.181.18.5766-5770.1999. PMC\u00a094098. PMID\u00a010482519.^ Parsek MR, Val DL, Hanzelka BL, Cronan JE, Greenberg EP (April 1999). “Acyl homoserine-lactone quorum-sensing signal generation”. Proceedings of the National Academy of Sciences of the United States of America. 96 (8): 4360\u20135. doi:10.1073\/pnas.96.8.4360. PMC\u00a016337. PMID\u00a010200267.^ Ulrich RL (October 2004). “Quorum quenching: enzymatic disruption of N-acylhomoserine lactone-mediated bacterial communication in Burkholderia thailandensis”. Applied and Environmental Microbiology. 70 (10): 6173\u201380. doi:10.1128\/AEM.70.10.6173-6180.2004. PMC\u00a0522112. PMID\u00a015466564.^ Gould TA, Schweizer HP, Churchill ME (August 2004). “Structure of the Pseudomonas aeruginosa acyl-homoserinelactone synthase LasI”. Molecular Microbiology. 53 (4): 1135\u201346. doi:10.1111\/j.1365-2958.2004.04211.x. PMID\u00a015306017.^ Raychaudhuri A, Jerga A, Tipton PA (March 2005). “Chemical mechanism and substrate specificity of RhlI, an acylhomoserine lactone synthase from Pseudomonas aeruginosa”. Biochemistry. 44 (8): 2974\u201381. doi:10.1021\/bi048005m. PMID\u00a015723540.^ Gould TA, Herman J, Krank J, Murphy RC, Churchill ME (January 2006). “Specificity of acyl-homoserine lactone synthases examined by mass spectrometry”. Journal of Bacteriology. 188 (2): 773\u201383. doi:10.1128\/JB.188.2.773-783.2006. PMC\u00a01347284. PMID\u00a016385066.External links[edit]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/acyl-homoserine-lactone-synthase-wikipedia\/#breadcrumbitem","name":"Acyl-homoserine-lactone synthase – Wikipedia"}}]}]