[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/cadps-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/cadps-wikipedia\/","headline":"CADPS &#8211; Wikipedia","name":"CADPS &#8211; Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Calcium-dependent secretion activator 1 is a","datePublished":"2016-12-07","dateModified":"2016-12-07","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/8c\/PDB_1wi1_EBI.jpg\/180px-PDB_1wi1_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/8c\/PDB_1wi1_EBI.jpg\/180px-PDB_1wi1_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/cadps-wikipedia\/","wordCount":3302,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensCalcium-dependent secretion activator 1 is a protein that in humans is encoded by the CADPS gene.[5][6]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4CADPS encodes a novel neural\/endocrine-specific cytosolic and peripheral membrane protein required for the Ca2+-regulated exocytosis of secretory vesicles. CADPS acts at a stage in exocytosis that follows ATP-dependent priming, which involves the essential synthesis of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). Alternative splicing has been observed at this locus and three variants, encoding distinct isoforms, are described.[6]References[edit]External links[edit]Further reading[edit]Nakajima D, Okazaki N, Yamakawa H,  et\u00a0al. (2003). &#8220;Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones&#8221;. DNA Res. 9 (3): 99\u2013106. doi:10.1093\/dnares\/9.3.99. PMID\u00a012168954.Nishizaki T, Walent JH, Kowalchyk JA, Martin TF (1992). &#8220;A key role for a 145-kDa cytosolic protein in the stimulation of Ca(2+)-dependent secretion by protein kinase C.&#8221; J. Biol. Chem. 267 (33): 23972\u201381. doi:10.1016\/S0021-9258(18)35932-5. PMID\u00a01429734.Ann K, Kowalchyk JA, Loyet KM, Martin TF (1997). &#8220;Novel Ca2+-binding protein (CAPS) related to UNC-31 required for Ca2+-activated exocytosis&#8221;. J. Biol. Chem. 272 (32): 19637\u201340. doi:10.1074\/jbc.272.32.19637. PMID\u00a09289490.Loyet KM, Kowalchyk JA, Chaudhary A,  et\u00a0al. (1998). &#8220;Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosis&#8221;. J. Biol. Chem. 273 (14): 8337\u201343. doi:10.1074\/jbc.273.14.8337. PMID\u00a09525942.Berwin B, Floor E, Martin TF (1998). &#8220;CAPS (mammalian UNC-31) protein localizes to membranes involved in dense-core vesicle exocytosis&#8221;. Neuron. 21 (1): 137\u201345. doi:10.1016\/S0896-6273(00)80521-8. PMID\u00a09697858.Hirosawa M, Nagase T, Ishikawa K,  et\u00a0al. (2000). &#8220;Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain&#8221;. DNA Res. 6 (5): 329\u201336. doi:10.1093\/dnares\/6.5.329. PMID\u00a010574461.Nakayama M, Kikuno R, Ohara O (2003). &#8220;Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs&#8221;. Genome Res. 12 (11): 1773\u201384. doi:10.1101\/gr.406902. PMC\u00a0187542. PMID\u00a012421765.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). &#8220;Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences&#8221;. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS&#8230;9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Cisternas FA, Vincent JB, Scherer SW, Ray PN (2003). &#8220;Cloning and characterization of human CADPS and CADPS2, new members of the Ca2+-dependent activator for secretion protein family&#8221;. Genomics. 81 (3): 279\u201391. doi:10.1016\/S0888-7543(02)00040-X. PMID\u00a012659812.Speidel D, Varoqueaux F, Enk C,  et\u00a0al. (2004). &#8220;A family of Ca2+-dependent activator proteins for secretion: comparative analysis of structure, expression, localization, and function&#8221;. J. Biol. Chem. 278 (52): 52802\u20139. doi:10.1074\/jbc.M304727200. PMID\u00a014530279.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). &#8220;Complete sequencing and characterization of 21,243 full-length human cDNAs&#8221;. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). &#8220;The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)&#8221;. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.Binda AV, Kabbani N, Levenson R (2005). &#8220;Regulation of dense core vesicle release from PC12 cells by interaction between the D2 dopamine receptor and calcium-dependent activator protein for secretion (CAPS)&#8221;. Biochem. Pharmacol. 69 (10): 1451\u201361. doi:10.1016\/j.bcp.2005.02.015. PMID\u00a015857609.PDB gallery1wi1: Solution structure of the PH domain of human calcium-dependent activator protein for secretion (CAPS)       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/cadps-wikipedia\/#breadcrumbitem","name":"CADPS &#8211; Wikipedia"}}]}]