[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/clic6-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/clic6-wikipedia\/","headline":"CLIC6 – Wikipedia","name":"CLIC6 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Chloride intracellular channel protein 6 is","datePublished":"2016-02-27","dateModified":"2016-02-27","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/clic6-wikipedia\/","about":["Wiki"],"wordCount":3639,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensChloride intracellular channel protein 6 is a protein that in humans is encoded by the CLIC6 gene.[5][6]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4The CLIC6 gene encodes a member of the chloride intracellular channel family of proteins. The gene is part of a large triplicated region found on chromosomes 1, 6, and 21. An alternatively spliced transcript variant has been described, but its biological validity has not been determined.[6]Table of ContentsInteractions[edit]See also[edit]References[edit]Further reading[edit]External links[edit]Interactions[edit]CLIC6 has been shown to interact with Dopamine receptor D3.[7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4See also[edit]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000159212 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022949 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Hattori M, Fujiyama A, Taylor TD, Watanabe H, Yada T, Park HS, Toyoda A, Ishii K, Totoki Y, Choi DK, Groner Y, Soeda E, Ohki M, Takagi T, Sakaki Y, Taudien S, Blechschmidt K, Polley A, Menzel U, Delabar J, Kumpf K, Lehmann R, Patterson D, Reichwald K, Rump A, Schillhabel M, Schudy A, Zimmermann W, Rosenthal A, Kudoh J, Schibuya K, Kawasaki K, Asakawa S, Shintani A, Sasaki T, Nagamine K, Mitsuyama S, Antonarakis SE, Minoshima S, Shimizu N, Nordsiek G, Hornischer K, Brant P, Scharfe M, Schon O, Desario A, Reichelt J, Kauer G, Blocker H, Ramser J, Beck A, Klages S, Hennig S, Riesselmann L, Dagand E, Haaf T, Wehrmeyer S, Borzym K, Gardiner K, Nizetic D, Francis F, Lehrach H, Reinhardt R, Yaspo ML (Jun 2000). “The DNA sequence of human chromosome 21”. Nature. 405 (6784): 311\u20139. Bibcode:2000Natur.405..311H. doi:10.1038\/35012518. PMID\u00a010830953.^ a b “Entrez Gene: CLIC6 chloride intracellular channel 6”.^ Griffon, Nathalie; Jeanneteau Freddy; Prieur Fanny; Diaz Jorge; Sokoloff Pierre (Sep 2003). “CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors”. Brain Res. Mol. Brain Res. Netherlands. 117 (1): 47\u201357. doi:10.1016\/S0169-328X(03)00283-3. ISSN\u00a00169-328X. PMID\u00a014499480.Further reading[edit]Singh H (2010). “Two decades with dimorphic Chloride Intracellular Channels (CLICs)”. FEBS Letters. 584 (10): 2112\u201321. doi:10.1016\/j.febslet.2010.03.013. PMID\u00a020226783. S2CID\u00a021056278.Hillier LD, Lennon G, Becker M,  et\u00a0al. (1997). “Generation and analysis of 280,000 human expressed sequence tags”. Genome Res. 6 (9): 807\u201328. doi:10.1101\/gr.6.9.807. PMID\u00a08889549.Strippoli P, D’Addabbo P, Lenzi L,  et\u00a0al. (2003). “Segmental paralogy in the human genome: a large-scale triplication on 1p, 6p, and 21q”. Mamm. Genome. 13 (8): 456\u201362. doi:10.1007\/s00335-001-2157-0. PMID\u00a012226712. S2CID\u00a026059147.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Scanlan MJ, Gout I, Gordon CM,  et\u00a0al. (2003). “Humoral immunity to human breast cancer: antigen definition and quantitative analysis of mRNA expression”. Cancer Immun. 1: 4. PMID\u00a012747765.Griffon N, Jeanneteau F, Prieur F,  et\u00a0al. (2003). “CLIC6, a member of the intracellular chloride channel family, interacts with dopamine D(2)-like receptors”. Brain Res. Mol. Brain Res. 117 (1): 47\u201357. doi:10.1016\/S0169-328X(03)00283-3. PMID\u00a014499480.Friedli M, Guipponi M, Bertrand S,  et\u00a0al. (2004). “Identification of a novel member of the CLIC family, CLIC6, mapping to 21q22.12”. Gene. 320: 31\u201340. doi:10.1016\/S0378-1119(03)00830-8. PMID\u00a014597386.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.External links[edit]This article incorporates text from the United States National Library of Medicine, which is in the public domain.       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