[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/ctdspl-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/ctdspl-wikipedia\/","headline":"CTDSPL – Wikipedia","name":"CTDSPL – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens CTD small phosphatase-like protein is an enzyme that","datePublished":"2017-12-21","dateModified":"2017-12-21","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/9\/91\/PDB_2hhl_EBI.png\/180px-PDB_2hhl_EBI.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/9\/91\/PDB_2hhl_EBI.png\/180px-PDB_2hhl_EBI.png","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/ctdspl-wikipedia\/","wordCount":3741,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensCTD small phosphatase-like protein is an enzyme that in humans is encoded by the CTDSPL gene.[5][6][7]Table of ContentsInteractions[edit]References[edit]Further reading[edit]External links[edit]Interactions[edit]CTDSPL has been shown to interact with SNAI1.[8]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000144677 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000047409 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Ishikawa S, Kai M, Tamari M, Takei Y, Takeuchi K, Bandou H, Yamane Y, Ogawa M, Nakamura Y (Aug 1997). “Sequence analysis of a 685-kb genomic region on chromosome 3p22-p21.3 that is homozygously deleted in a lung carcinoma cell line”. DNA Res. 4 (1): 35\u201343. doi:10.1093\/dnares\/4.1.35. PMID\u00a09179494.^ Protopopov A, Kashuba V, Zabarovska VI, Muravenko OV, Lerman MI, Klein G, Zabarovsky ER (Jan 2003). “An integrated physical and gene map of the 3.5-Mb chromosome 3p21.3 (AP20) region implicated in major human epithelial malignancies”. Cancer Res. 63 (2): 404\u201312. PMID\u00a012543795.^ “Entrez Gene: CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like”.^ Wu, Yadi; Evers B Mark; Zhou Binhua P (Jan 2009). “Small C-terminal domain phosphatase enhances snail activity through dephosphorylation”. J. Biol. Chem. United States. 284 (1): 640\u20138. doi:10.1074\/jbc.M806916200. ISSN\u00a00021-9258. PMC\u00a02610500. PMID\u00a019004823.Further reading[edit]O’Keeffe B, Fong Y, Chen D,  et\u00a0al. (2000). “Requirement for a kinase-specific chaperone pathway in the production of a Cdk9\/cyclin T1 heterodimer responsible for P-TEFb-mediated tat stimulation of HIV-1 transcription”. J. Biol. Chem. 275 (1): 279\u201387. doi:10.1074\/jbc.275.1.279. PMID\u00a010617616.Kim JB, Sharp PA (2001). “Positive transcription elongation factor B phosphorylates hSPT5 and RNA polymerase II carboxyl-terminal domain independently of cyclin-dependent kinase-activating kinase”. J. Biol. Chem. 276 (15): 12317\u201323. doi:10.1074\/jbc.M010908200. PMID\u00a011145967.Ramanathan Y, Rajpara SM, Reza SM,  et\u00a0al. (2001). “Three RNA polymerase II carboxyl-terminal domain kinases display distinct substrate preferences”. J. Biol. Chem. 276 (14): 10913\u201320. doi:10.1074\/jbc.M010975200. PMID\u00a011278802.Zhou M, Nekhai S, Bharucha DC,  et\u00a0al. (2002). “TFIIH inhibits CDK9 phosphorylation during human immunodeficiency virus type 1 transcription”. J. Biol. Chem. 276 (48): 44633\u201340. doi:10.1074\/jbc.M107466200. PMID\u00a011572868.Lin X, Taube R, Fujinaga K, Peterlin BM (2002). “P-TEFb containing cyclin K and Cdk9 can activate transcription via RNA”. J. Biol. Chem. 277 (19): 16873\u20138. doi:10.1074\/jbc.M200117200. PMID\u00a011884399.Kim YK, Bourgeois CF, Isel C,  et\u00a0al. (2002). “Phosphorylation of the RNA polymerase II carboxyl-terminal domain by CDK9 is directly responsible for human immunodeficiency virus type 1 Tat-activated transcriptional elongation”. Mol. Cell. Biol. 22 (13): 4622\u201337. doi:10.1128\/MCB.22.13.4622-4637.2002. PMC\u00a0133925. PMID\u00a012052871.Yeo M, Lin PS, Dahmus ME, Gill GN (2003). “A novel RNA polymerase II C-terminal domain phosphatase that preferentially dephosphorylates serine 5”. J. Biol. Chem. 278 (28): 26078\u201385. doi:10.1074\/jbc.M301791200. PMID\u00a012721286.Pinhero R, Liaw P, Bertens K, Yankulov K (2004). “Three cyclin-dependent kinases preferentially phosphorylate different parts of the C-terminal domain of the large subunit of RNA polymerase II”. Eur. J. Biochem. 271 (5): 1004\u201314. doi:10.1111\/j.1432-1033.2004.04002.x. PMID\u00a015009212.Kashuba VI, Li J, Wang F,  et\u00a0al. (2004). “RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies”. Proc. Natl. Acad. Sci. U.S.A. 101 (14): 4906\u201311. Bibcode:2004PNAS..101.4906K. doi:10.1073\/pnas.0401238101. PMC\u00a0387347. PMID\u00a015051889.External links[edit]PDB gallery2hhl: Crystal structure of the human small CTD phosphatase 3 isoform 1  "},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/ctdspl-wikipedia\/#breadcrumbitem","name":"CTDSPL – Wikipedia"}}]}]