[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/dleu2-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/dleu2-wikipedia\/","headline":"DLEU2 – Wikipedia","name":"DLEU2 – Wikipedia","description":"From Wikipedia, the free encyclopedia Non-coding RNA in the species Homo sapiens DLEU2 Identifiers Aliases DLEU2, 1B4, BCMSUN, DLB2, LEU2,","datePublished":"2019-07-02","dateModified":"2019-07-02","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/dleu2-wikipedia\/","about":["Wiki"],"wordCount":3184,"articleBody":"From Wikipedia, the free encyclopediaNon-coding RNA in the species Homo sapiensDLEU2IdentifiersAliasesDLEU2, 1B4, BCMSUN, DLB2, LEU2, LINC00022, MIR15AHG, NCRNA00022, RFP2OS, TRIM13OS, deleted in lymphocytic leukemia 2 (non-protein coding)External IDsOMIM: 605766 GeneCards: DLEU2 WikidataDeleted in lymphocytic leukemia 2 (non-protein coding) is a long non-coding RNA that in humans is encoded by the DLEU2 gene. In humans it is located on chromosome 13q14.[2][3][4] The DLEU2 gene was originally identified as a potential tumour suppressor gene and is often deleted in patients with B-cell chronic lymphocytic leukemia.[2]See also[edit]References[edit]^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ a b Liu Y, Corcoran M, Rasool O, Ivanova G, Ibbotson R, Grand\u00e9r D, Iyengar A, Baranova A, Kashuba V, Merup M, Wu X, Gardiner A, Mullenbach R, Poltaraus A, Hultstr\u00f6m AL, Juliusson G, Chapman R, Tiller M, Cotter F, Gahrton G, Yankovsky N, Zabarovsky E, Einhorn S, Oscier D (Nov 1997). “Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia”. Oncogene. 15 (20): 2463\u20132473. doi:10.1038\/sj.onc.1201643. PMID\u00a09395242. S2CID\u00a021133945.^ Mertens D, Wolf S, Bullinger L, Ohl S, Schaffner C, D\u00f6hner H, Stilgenbauer S, Lichter P (Dec 2000). “BCMSUN, a candidate gene for B-cell chronic lymphocytic leukemia and mantle-cell lymphoma, has an independently expressed homolog on 1p22-p31, BCMSUN-like”. International Journal of Cancer. 88 (5): 692\u2013697. doi:10.1002\/1097-0215(20001201)88:53.0.CO;2-3. PMID\u00a011072235.^ “Entrez Gene: DLEU2 deleted in lymphocytic leukemia, 2”.Further reading[edit]Kapanadze B, Makeeva N, Corcoran M, Jareborg N, Hammarsund M, Baranova A, Zabarovsky E, Vorontsova O, Merup M, Gahrton G, Jansson M, Yankovsky N, Einhorn S, Oscier D, Grand\u00e9r D, Sangfelt O (Dec 2000). “Comparative sequence analysis of a region on human chromosome 13q14, frequently deleted in B-cell chronic lymphocytic leukemia, and its homologous region on mouse chromosome 14”. Genomics. 70 (3): 327\u2013334. doi:10.1006\/geno.2000.6386. PMID\u00a011161783.Migliazza A, Bosch F, Komatsu H, Cayanis E, Martinotti S, Toniato E, Guccione E, Qu X, Chien M, Murty VV, Gaidano G, Inghirami G, Zhang P, Fischer S, Kalachikov SM, Russo J, Edelman I, Efstratiadis A, Dalla-Favera R (Apr 2001). “Nucleotide sequence, transcription map, and mutation analysis of the 13q14 chromosomal region deleted in B-cell chronic lymphocytic leukemia”. Blood. 97 (7): 2098\u20132104. doi:10.1182\/blood.V97.7.2098. PMID\u00a011264177.Bullrich F, Fujii H, Calin G, Mabuchi H, Negrini M, Pekarsky Y, Rassenti L, Alder H, Reed JC, Keating MJ, Kipps TJ, Croce CM (Sep 2001). “Characterization of the 13q14 tumor suppressor locus in CLL: identification of ALT1, an alternative splice variant of the LEU2 gene”. Cancer Research. 61 (18): 6640\u20136648. PMID\u00a011559527.Baranova A, Hammarsund M, Ivanov D, Skoblov M, Sangfelt O, Corcoran M, Borodina T, Makeeva N, Pestova A, Tyazhelova T, Nazarenko S, Gorreta F, Alsheddi T, Schlauch K, Nikitin E, Kapanadze B, Shagin D, Poltaraus A, Ivanovich Vorobiev A, Zabarovsky E, Lukianov S, Chandhoke V, Ibbotson R, Oscier D, Einhorn S, Grander D, Yankovsky N (Dec 2003). “Distinct organization of the candidate tumor suppressor gene RFP2 in human and mouse: multiple mRNA isoforms in both species- and human-specific antisense transcript RFP2OS”. Gene. 321: 103\u2013112. doi:10.1016\/j.gene.2003.08.007. PMID\u00a014636997.Corcoran MM, Hammarsund M, Zhu C, Lerner M, Kapanadze B, Wilson B, Larsson C, Forsberg L, Ibbotson RE, Einhorn S, Oscier DG, Grand\u00e9r D, Sangfelt O (Aug 2004). “DLEU2 encodes an antisense RNA for the putative bicistronic RFP2\/LEU5 gene in humans and mouse”. Genes, Chromosomes & Cancer. 40 (4): 285\u2013297. doi:10.1002\/gcc.20046. PMID\u00a015188451. S2CID\u00a035917986.Skoblov M, Shakhbazov K, Oshchepkov D, Ivanov D, Guskova A, Ivanov D, Rubtsov P, Prasolov V, Yankovsky N, Baranova A (Apr 2006). “Human RFP2 gene promoter: unique structure and unusual strength”. Biochemical and Biophysical Research Communications. 342 (3): 859\u2013866. doi:10.1016\/j.bbrc.2006.01.187. PMC\u00a01994241. PMID\u00a016499869.  "},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/dleu2-wikipedia\/#breadcrumbitem","name":"DLEU2 – Wikipedia"}}]}]