[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/eif3k-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/eif3k-wikipedia\/","headline":"EIF3K – Wikipedia","name":"EIF3K – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens EIF3K Identifiers Aliases EIF3K, EIF3-p28, EIF3S12,","datePublished":"2019-11-20","dateModified":"2019-11-20","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/4\/47\/PDB_1rz4_EBI.jpg\/180px-PDB_1rz4_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/4\/47\/PDB_1rz4_EBI.jpg\/180px-PDB_1rz4_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/eif3k-wikipedia\/","wordCount":4089,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensEIF3KIdentifiersAliasesEIF3K, EIF3-p28, EIF3S12, HSPC029, M9, MSTP001, PLAC-24, PLAC24, PRO1474, PTD001, ARG134, eukaryotic translation initiation factor 3 subunit KExternal IDsOMIM: 609596 MGI: 1921080 HomoloGene: 8292 GeneCards: EIF3K WikidataEukaryotic translation initiation factor 3 subunit K (eIF3k) is a protein that in humans is encoded by the EIF3K gene.[5][6][7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Table of ContentsFunction[edit]Interactions[edit]See also[edit]References[edit]Further reading[edit]External links[edit]Function[edit]The ~800 kDa eukaryotic initiation factor 3 (eIF3) is the largest eIF and contains at least 12 subunits, including eIF3k\/EIF2S12. eIF3 plays an essential role in translation by binding directly to the 40S ribosomal subunit and promoting formation of the 43S preinitiation complex.[8][7]Interactions[edit]eIF3k has been shown to interact with Cyclin D3[9] and eIF3a.[6][10]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4See also[edit]References[edit]^ a b c ENSG00000282986 GRCh38: Ensembl release 89: ENSG00000178982, ENSG00000282986 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000053565 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ,  et\u00a0al. (October 2000). “Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem\/progenitor cells”. Genome Research. 10 (10): 1546\u201360. doi:10.1101\/gr.140200. PMC\u00a0310934. PMID\u00a011042152.^ a b Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (October 2003). “Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3”. European Journal of Biochemistry. 270 (20): 4133\u20139. doi:10.1046\/j.1432-1033.2003.03807.x. PMID\u00a014519125.^ a b “Entrez Gene: EIF3S12 eukaryotic translation initiation factor 3, subunit 12”.^ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (2003). “Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3”. European Journal of Biochemistry. 270 (20): 4133\u20139. doi:10.1046\/j.1432-1033.2003.03807.x. PMID\u00a014519125.^ Shen X, Yang Y, Liu W, Sun M, Jiang J, Zong H, Gu J (August 2004). “Identification of the p28 subunit of eukaryotic initiation factor 3 (eIF3k) as a new interaction partner of cyclin D3”. FEBS Letters. 573 (1\u20133): 139\u201346. doi:10.1016\/j.febslet.2004.07.071. PMID\u00a015327989. S2CID\u00a016005938.^ Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S,  et\u00a0al. (2007). “Large-scale mapping of human protein-protein interactions by mass spectrometry”. Molecular Systems Biology. 3 (1): 89. doi:10.1038\/msb4100134. PMC\u00a01847948. PMID\u00a017353931.Further reading[edit]Karki S, Ligon LA, DeSantis J, Tokito M, Holzbaur EL (May 2002). “PLAC-24 is a cytoplasmic dynein-binding protein that is recruited to sites of cell-cell contact”. Molecular Biology of the Cell. 13 (5): 1722\u201334. doi:10.1091\/mbc.02-02-0011. PMC\u00a0111139. PMID\u00a012006665.Wei Z, Zhang P, Zhou Z, Cheng Z, Wan M, Gong W (August 2004). “Crystal structure of human eIF3k, the first structure of eIF3 subunits”. The Journal of Biological Chemistry. 279 (33): 34983\u201390. doi:10.1074\/jbc.M405158200. PMID\u00a015180986.Shen X, Yang Y, Liu W, Sun M, Jiang J, Zong H, Gu J (August 2004). “Identification of the p28 subunit of eukaryotic initiation factor 3(eIF3k) as a new interaction partner of cyclin D3”. FEBS Letters. 573 (1\u20133): 139\u201346. doi:10.1016\/j.febslet.2004.07.071. PMID\u00a015327989. S2CID\u00a016005938.Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks”. Cell. 127 (3): 635\u201348. doi:10.1016\/j.cell.2006.09.026. PMID\u00a017081983. S2CID\u00a07827573.External links[edit]Overview of all the structural information available in the PDB for UniProt: Q9UBQ5 (Human Eukaryotic translation initiation factor 3 subunit K (EIF3K)) at the PDBe-KB.PDB gallery1rz4: Crystal Structure of Human eIF3k       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/eif3k-wikipedia\/#breadcrumbitem","name":"EIF3K – Wikipedia"}}]}]