[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/erp29-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/erp29-wikipedia\/","headline":"ERP29 – Wikipedia","name":"ERP29 – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens Endoplasmic reticulum protein 29 (ERp29) is a chaperone","datePublished":"2015-02-08","dateModified":"2015-02-08","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/3\/37\/PDB_1g7e_EBI.jpg\/180px-PDB_1g7e_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/3\/37\/PDB_1g7e_EBI.jpg\/180px-PDB_1g7e_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/erp29-wikipedia\/","wordCount":3885,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensEndoplasmic reticulum protein 29 (ERp29) is a chaperone protein that in humans is encoded by the ERP29 gene.[5]Function[edit]ERp29 is a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide-isomerase family.[6] However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase.[6] The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms.[5]References[edit]Further reading[edit]Hubbard MJ (Sep 2002). “Functional proteomics: The goalposts are moving”. Proteomics. 2 (9): 1069\u201378. doi:10.1002\/1615-9861(200209)2:93.0.CO;2-R. PMID\u00a012362325. S2CID\u00a046402626.Mkrtchian S, Sandalova T (2006). “ERp29, an unusual redox-inactive member of the thioredoxin family”. Antioxidants & Redox Signaling. 8 (3\u20134): 325\u201337. doi:10.1089\/ars.2006.8.325. PMID\u00a016677078.Hochstrasser DF, Frutiger S, Paquet N, Bairoch A, Ravier F, Pasquali C, Sanchez JC, Tissot JD, Bjellqvist B, Vargas R (Dec 1992). “Human liver protein map: a reference database established by microsequencing and gel comparison”. Electrophoresis. 13 (12): 992\u20131001. doi:10.1002\/elps.11501301201. PMID\u00a01286669. S2CID\u00a023518983.Hughes GJ, Frutiger S, Paquet N, Pasquali C, Sanchez JC, Tissot JD, Bairoch A, Appel RD, Hochstrasser DF (Nov 1993). “Human liver protein map: update 1993”. Electrophoresis. 14 (11): 1216\u201322. doi:10.1002\/elps.11501401181. PMID\u00a08313870. S2CID\u00a033424554.Mkrtchian S, Fang C, Hellman U, Ingelman-Sundberg M (Jan 1998). “A stress-inducible rat liver endoplasmic reticulum protein, ERp29”. European Journal of Biochemistry. 251 (1\u20132): 304\u201313. doi:10.1046\/j.1432-1327.1998.2510304.x. PMID\u00a09492298.Ferrari DM, Nguyen Van P, Kratzin HD, S\u00f6ling HD (Aug 1998). “ERp28, a human endoplasmic-reticulum-lumenal protein, is a member of the protein disulfide isomerase family but lacks a CXXC thioredoxin-box motif”. European Journal of Biochemistry. 255 (3): 570\u20139. doi:10.1046\/j.1432-1327.1998.2550570.x. PMID\u00a09738895.Hubbard MJ, McHugh NJ (Nov 2000). “Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping”. Electrophoresis. 21 (17): 3785\u201396. doi:10.1002\/1522-2683(200011)21:173.0.CO;2-2. PMID\u00a011271497. S2CID\u00a042538820.Shnyder SD, Hubbard MJ (Apr 2002). “ERp29 is a ubiquitous resident of the endoplasmic reticulum with a distinct role in secretory protein production”. The Journal of Histochemistry and Cytochemistry. 50 (4): 557\u201366. doi:10.1177\/002215540205000413. PMID\u00a011897809.Sargsyan E, Baryshev M, Backlund M, Sharipo A, Mkrtchian S (Feb 2002). “Genomic organization and promoter characterization of the gene encoding a putative endoplasmic reticulum chaperone, ERp29”. Gene. 285 (1\u20132): 127\u201339. CiteSeerX\u00a010.1.1.593.9369. doi:10.1016\/S0378-1119(02)00417-1. PMID\u00a012039039.Basrur V, Yang F, Kushimoto T, Higashimoto Y, Yasumoto K, Valencia J, Muller J, Vieira WD, Watabe H, Shabanowitz J, Hearing VJ, Hunt DF, Appella E (2003). “Proteomic analysis of early melanosomes: identification of novel melanosomal proteins”. Journal of Proteome Research. 2 (1): 69\u201379. doi:10.1021\/pr025562r. PMID\u00a012643545.Lim J, Hao T, Shaw C, Patel AJ, Szab\u00f3 G, Rual JF, Fisk CJ, Li N, Smolyar A, Hill DE, Barab\u00e1si AL, Vidal M, Zoghbi HY (May 2006). “A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration”. Cell. 125 (4): 801\u201314. doi:10.1016\/j.cell.2006.03.032. PMID\u00a016713569. S2CID\u00a013709685.Cheretis C, Dietrich F, Chatzistamou I, Politi K, Angelidou E, Kiaris H, Mkrtchian S, Koutselini H (Oct 2006). “Expression of ERp29, an endoplasmic reticulum secretion factor in basal-cell carcinoma”. The American Journal of Dermatopathology. 28 (5): 410\u20132. doi:10.1097\/01.dad.0000211521.49810.ac. PMID\u00a017012915. S2CID\u00a01661765.Zheng J, Liu X, Yan X, Dai L, Ji C (2006). “Purification and structural characterization of human ERp29”. Protein and Peptide Letters. 13 (8): 753\u20139. doi:10.2174\/092986606777841190. PMID\u00a017073718.Chi A, Valencia JC, Hu ZZ, Watabe H, Yamaguchi H, Mangini NJ, Huang H, Canfield VA, Cheng KC, Yang F, Abe R, Yamagishi S, Shabanowitz J, Hearing VJ, Wu C, Appella E, Hunt DF (Nov 2006). “Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes”. Journal of Proteome Research. 5 (11): 3135\u201344. doi:10.1021\/pr060363j. PMID\u00a017081065.Lippert U, Diao D, Barak NN, Ferrari DM (Apr 2007). “Conserved structural and functional properties of D-domain containing redox-active and -inactive protein disulfide isomerase-related protein chaperones” (PDF). The Journal of Biological Chemistry. 282 (15): 11213\u201320. doi:10.1074\/jbc.M604440200. PMID\u00a017296603. S2CID\u00a025822309.PDB gallery1g7e: NMR STRUCTURE OF N-DOMAIN OF ERP29 PROTEIN  "},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/erp29-wikipedia\/#breadcrumbitem","name":"ERP29 – Wikipedia"}}]}]