[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/gsto1-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/gsto1-wikipedia\/","headline":"GSTO1 – Wikipedia","name":"GSTO1 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Mammalian protein found in Homo sapiens Glutathione S-transferase omega-1 is an enzyme that","datePublished":"2018-01-05","dateModified":"2018-01-05","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/f\/ff\/PDB_1eem_EBI.jpg\/180px-PDB_1eem_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/f\/ff\/PDB_1eem_EBI.jpg\/180px-PDB_1eem_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/gsto1-wikipedia\/","wordCount":5867,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Mammalian protein found in Homo sapiensGlutathione S-transferase omega-1 is an enzyme that in humans is encoded by the GSTO1 gene.[5][6][7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4This gene encodes a member of the theta class glutathione S-transferase-like (GSTTL) protein family. In mouse, the encoded protein acts as a small stress response protein, likely involved in cellular redox homeostasis.[7] This protein has dehydroascorbate reductase activity and may function in the glutathione-ascorbate cycle as part of antioxidant metabolism.[8]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000148834 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025068 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF, Pandit J (Sep 2000). “Identification, characterization, and crystal structure of the Omega class glutathione transferases”. J Biol Chem. 275 (32): 24798\u2013806. doi:10.1074\/jbc.M001706200. PMID\u00a010783391.^ Whitbread AK, Tetlow N, Eyre HJ, Sutherland GR, Board PG (Mar 2003). “Characterization of the human Omega class glutathione transferase genes and associated polymorphisms”. Pharmacogenetics. 13 (3): 131\u201344. doi:10.1097\/00008571-200303000-00003. PMID\u00a012618591.^ a b “Entrez Gene: GSTO1 glutathione S-transferase omega 1”.^ Whitbread AK, Masoumi A, Tetlow N, Schmuck E, Coggan M, Board PG (2005). “Characterization of the omega class of glutathione transferases”. Meth. Enzymol. Methods in Enzymology. 401: 78\u201399. doi:10.1016\/S0076-6879(05)01005-0. ISBN\u00a0978-0-12-182806-6. PMID\u00a016399380.Further reading[edit]Matoba R, Okubo K, Hori N,  et\u00a0al. (1994). “The addition of 5′-coding information to a 3′-directed cDNA library improves analysis of gene expression”. Gene. 146 (2): 199\u2013207. doi:10.1016\/0378-1119(94)90293-3. PMID\u00a08076819.Ishikawa T, Casini AF, Nishikimi M (1998). “Molecular cloning and functional expression of rat liver glutathione-dependent dehydroascorbate reductase”. J. Biol. Chem. 273 (44): 28708\u201312. doi:10.1074\/jbc.273.44.28708. PMID\u00a09786866.Kodym R, Calkins P, Story M (1999). “The cloning and characterization of a new stress response protein. A mammalian member of a family of theta class glutathione s-transferase-like proteins”. J. Biol. Chem. 274 (8): 5131\u20137. doi:10.1074\/jbc.274.8.5131. PMID\u00a09988762.Hubbard MJ, McHugh NJ (2001). “Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping”. Electrophoresis. 21 (17): 3785\u201396. doi:10.1002\/1522-2683(200011)21:173.0.CO;2-2. PMID\u00a011271497. S2CID\u00a042538820.Yin ZL, Dahlstrom JE, Le Couteur DG, Board PG (2001). “Immunohistochemistry of omega class glutathione S-transferase in human tissues”. J. Histochem. Cytochem. 49 (8): 983\u20137. doi:10.1177\/002215540104900806. PMID\u00a011457926.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Tanaka-Kagawa T, Jinno H, Hasegawa T,  et\u00a0al. (2003). “Functional characterization of two variant human GSTO 1-1s (Ala140Asp and Thr217Asn)”. Biochem. Biophys. Res. Commun. 301 (2): 516\u201320. doi:10.1016\/S0006-291X(02)03066-8. PMID\u00a012565892.Yu L, Kalla K, Guthrie E,  et\u00a0al. (2004). “Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans”. Environ. Health Perspect. 111 (11): 1421\u20137. doi:10.1289\/ehp.6420. PMC\u00a01241635. PMID\u00a012928150.Li YJ, Oliveira SA, Xu P,  et\u00a0al. (2004). “Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease”. Hum. Mol. Genet. 12 (24): 3259\u201367. doi:10.1093\/hmg\/ddg357. PMID\u00a014570706.Whitbread AK, Mellick GD, Silburn PA,  et\u00a0al. (2004). “Glutathione transferase Omega class polymorphisms in Parkinson disease”. Neurology. 62 (10): 1910\u20131. doi:10.1212\/01.wnl.0000125282.09308.b1. PMID\u00a015159516. S2CID\u00a046505059.Deloukas P, Earthrowl ME, Grafham DV,  et\u00a0al. (2004). “The DNA sequence and comparative analysis of human chromosome 10”. Nature. 429 (6990): 375\u201381. Bibcode:2004Natur.429..375D. doi:10.1038\/nature02462. PMID\u00a015164054.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.K\u00f6lsch H, Linnebank M, L\u00fctjohann D,  et\u00a0al. (2005). “Polymorphisms in glutathione S-transferase omega-1 and AD, vascular dementia, and stroke”. Neurology. 63 (12): 2255\u201360. doi:10.1212\/01.wnl.0000147294.29309.47. PMID\u00a015623683. S2CID\u00a021431373.Ozturk A, Desai PP, Minster RL,  et\u00a0al. (2005). “Three SNPs in the GSTO1, GSTO2 and PRSS11 genes on chromosome 10 are not associated with age-at-onset of Alzheimer’s disease”. Neurobiol. Aging. 26 (8): 1161\u20135. doi:10.1016\/j.neurobiolaging.2004.11.001. PMID\u00a015917099. S2CID\u00a010878355.Stelzl U, Worm U, Lalowski M,  et\u00a0al. (2005). “A human protein-protein interaction network: a resource for annotating the proteome”. Cell. 122 (6): 957\u201368. doi:10.1016\/j.cell.2005.08.029. hdl:11858\/00-001M-0000-0010-8592-0. PMID\u00a016169070. S2CID\u00a08235923.Fujihara J, Kunito T, Takeshita H (2007). “Frequency of two human glutathione-S-transferase omega-1 polymorphisms (E155 deletion and E208K) in Ovambo and Japanese populations using the PCR-based genotyping method”. Clin. Chem. Lab. Med. 45 (5): 621\u20134. doi:10.1515\/CCLM.2007.128. PMID\u00a017484623. S2CID\u00a01553700.Harju TH, Peltoniemi MJ, Rytil\u00e4 PH,  et\u00a0al. (2007). “Glutathione S-transferase omega in the lung and sputum supernatants of COPD patients”. Respir. Res. 8 (1): 48. doi:10.1186\/1465-9921-8-48. PMC\u00a01939846. PMID\u00a017617905.K\u00f6lsch H, Larionov S, Dedeck O,  et\u00a0al. (2007). “Association of the glutathione S-transferase omega-1 Ala140Asp polymorphism with cerebrovascular atherosclerosis and plaque-associated interleukin-1 alpha expression”. Stroke. 38 (10): 2847\u201350. doi:10.1161\/STROKEAHA.107.484162. PMID\u00a017717316.PDB gallery1eem: GLUTATHIONE TRANSFERASE FROM HOMO SAPIENS       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/gsto1-wikipedia\/#breadcrumbitem","name":"GSTO1 – Wikipedia"}}]}]