[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/hist1h2bk-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/hist1h2bk-wikipedia\/","headline":"HIST1H2BK – Wikipedia","name":"HIST1H2BK – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens Histone H2B type 1-K is a protein that","datePublished":"2019-09-23","dateModified":"2019-09-23","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/d\/de\/PDB_1aoi_EBI.jpg\/180px-PDB_1aoi_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/d\/de\/PDB_1aoi_EBI.jpg\/180px-PDB_1aoi_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/hist1h2bk-wikipedia\/","wordCount":9664,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensHistone H2B type 1-K is a protein that in humans is encoded by the HIST1H2BK gene.[5][6]Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a member of the histone H2B family. This gene is found in the histone microcluster on chromosome 6p21.33.[6]Interactions[edit]HIST1H2BK has been shown to interact with HIRA.[7]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000197903 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000062727 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Marzluff WF, Gongidi P, Woods KR, Jin J, Maltais LJ (Oct 2002). “The human and mouse replication-dependent histone genes”. Genomics. 80 (5): 487\u201398. doi:10.1016\/S0888-7543(02)96850-3. PMID\u00a012408966.^ a b “Entrez Gene: HIST1H2BK histone cluster 1, H2bk”.^ Lorain, S; Quivy J P; Monier-Gavelle F; Scamps C; L\u00e9cluse Y; Almouzni G; Lipinski M (Sep 1998). “Core Histones and HIRIP3, a Novel Histone-Binding Protein, Directly Interact with WD Repeat Protein HIRA”. Mol. Cell. Biol. UNITED STATES. 18 (9): 5546\u201356. doi:10.1128\/MCB.18.9.5546. ISSN\u00a00270-7306. PMC\u00a0109139. PMID\u00a09710638.Further reading[edit]Dobner T, Wolf I, Mai B, Lipp M (1992). “A novel divergently transcribed human histone H2A\/H2B gene pair”. DNA Seq. 1 (6): 409\u201313. doi:10.3109\/10425179109020799. PMID\u00a01768865.Frohm M, Gunne H, Bergman AC,  et\u00a0al. (1996). “Biochemical and antibacterial analysis of human wound and blister fluid”. Eur. J. Biochem. 237 (1): 86\u201392. doi:10.1111\/j.1432-1033.1996.0086n.x. PMID\u00a08620898.El Kharroubi A, Piras G, Zensen R, Martin MA (1998). “Transcriptional Activation of the Integrated Chromatin-Associated Human Immunodeficiency Virus Type 1 Promoter”. Mol. Cell. Biol. 18 (5): 2535\u201344. doi:10.1128\/mcb.18.5.2535. PMC\u00a0110633. PMID\u00a09566873.Lorain S, Quivy JP, Monier-Gavelle F,  et\u00a0al. (1998). “Core Histones and HIRIP3, a Novel Histone-Binding Protein, Directly Interact with WD Repeat Protein HIRA”. Mol. Cell. Biol. 18 (9): 5546\u201356. doi:10.1128\/MCB.18.9.5546. PMC\u00a0109139. PMID\u00a09710638.Albig W, Trappe R, Kardalinou E,  et\u00a0al. (1999). “The human H2A and H2B histone gene complement”. Biol. Chem. 380 (1): 7\u201318. doi:10.1515\/BC.1999.002. PMID\u00a010064132. S2CID\u00a012807248.Ahn J, Gruen JR (1999). “The genomic organization of the histone clusters on human 6p21.3”. Mamm. Genome. 10 (7): 768\u201370. doi:10.1007\/s003359901089. PMID\u00a010384058. S2CID\u00a028275496.Deng L, de la Fuente C, Fu P,  et\u00a0al. (2001). “Acetylation of HIV-1 Tat by CBP\/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones”. Virology. 277 (2): 278\u201395. doi:10.1006\/viro.2000.0593. PMID\u00a011080476.Deng L, Wang D, de la Fuente C,  et\u00a0al. (2001). “Enhancement of the p300 HAT activity by HIV-1 Tat on chromatin DNA”. Virology. 289 (2): 312\u201326. doi:10.1006\/viro.2001.1129. PMID\u00a011689053.Kim HS, Cho JH, Park HW,  et\u00a0al. (2002). “Endotoxin-neutralizing antimicrobial proteins of the human placenta”. J. Immunol. 168 (5): 2356\u201364. doi:10.4049\/jimmunol.168.5.2356. PMID\u00a011859126.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Cheung WL, Ajiro K, Samejima K,  et\u00a0al. (2003). “Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase”. Cell. 113 (4): 507\u201317. doi:10.1016\/S0092-8674(03)00355-6. PMID\u00a012757711. S2CID\u00a021854.Tollin M, Bergman P, Svenberg T,  et\u00a0al. (2004). “Antimicrobial peptides in the first line defence of human colon mucosa”. Peptides. 24 (4): 523\u201330. doi:10.1016\/S0196-9781(03)00114-1. PMID\u00a012860195. S2CID\u00a07435936.Mungall AJ, Palmer SA, Sims SK,  et\u00a0al. (2003). “The DNA sequence and analysis of human chromosome 6”. Nature. 425 (6960): 805\u201311. Bibcode:2003Natur.425..805M. doi:10.1038\/nature02055. PMID\u00a014574404.Lusic M, Marcello A, Cereseto A, Giacca M (2004). “Regulation of HIV-1 gene expression by histone acetylation and factor recruitment at the LTR promoter”. EMBO J. 22 (24): 6550\u201361. doi:10.1093\/emboj\/cdg631. PMC\u00a0291826. PMID\u00a014657027.Howell SJ, Wilk D, Yadav SP, Bevins CL (2004). “Antimicrobial polypeptides of the human colonic epithelium”. Peptides. 24 (11): 1763\u201370. doi:10.1016\/j.peptides.2003.07.028. PMID\u00a015019208. S2CID\u00a028953527.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.Andersen JS, Lam YW, Leung AK,  et\u00a0al. (2005). “Nucleolar proteome dynamics”. Nature. 433 (7021): 77\u201383. Bibcode:2005Natur.433…77A. doi:10.1038\/nature03207. PMID\u00a015635413. S2CID\u00a04344740.Tsunaka Y, Kajimura N, Tate S, Morikawa K (2005). “Alteration of the nucleosomal DNA path in the crystal structure of a human nucleosome core particle”. Nucleic Acids Res. 33 (10): 3424\u201334. doi:10.1093\/nar\/gki663. PMC\u00a01150222. PMID\u00a015951514.Golebiowski F, Kasprzak KS (2007). “Inhibition of core histones acetylation by carcinogenic nickel(II)”. Mol. Cell. Biochem. 279 (1\u20132): 133\u20139. doi:10.1007\/s11010-005-8285-1. PMID\u00a016283522. S2CID\u00a025071586.PDB gallery1aoi: COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT1eqz: X-RAY STRUCTURE OF THE NUCLEOSOME CORE PARTICLE AT 2.5 A RESOLUTION1f66: 2.6 A CRYSTAL STRUCTURE OF A NUCLEOSOME CORE PARTICLE CONTAINING THE VARIANT HISTONE H2A.Z1hq3: CRYSTAL STRUCTURE OF THE HISTONE-CORE-OCTAMER IN KCL\/PHOSPHATE1kx3: X-Ray Structure of the Nucleosome Core Particle, NCP146, at 2.0 A Resolution1kx4: X-Ray Structure of the Nucleosome Core Particle, NCP146b, at 2.6 A Resolution1kx5: X-Ray Structure of the Nucleosome Core Particle, NCP147, at 1.9 A Resolution1m18: LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA1m19: LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA1m1a: LIGAND BINDING ALTERS THE STRUCTURE AND DYNAMICS OF NUCLEOSOMAL DNA1p34: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3a: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3b: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3f: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3g: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3i: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3k: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3l: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3m: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3o: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1p3p: Crystallographic Studies of Nucleosome Core Particles containing Histone ‘Sin’ Mutants1s32: Molecular Recognition of the Nucleosomal ‘Supergroove’1tzy: Crystal Structure of the Core-Histone Octamer to 1.90 Angstrom Resolution1u35: Crystal structure of the nucleosome core particle containing the histone domain of macroH2A1zbb: Structure of the 4_601_167 Tetranucleosome1zla: X-ray Structure of a Kaposi’s sarcoma herpesvirus LANA peptide bound to the nucleosomal core2aro: Crystal Structure Of The Native Histone Octamer To 2.1 Angstrom Resolution, Crystalised In The Presence Of S-Nitrosoglutathione2cv5: Crystal structure of human nucleosome core particle2f8n: 2.9 Angstrom X-ray structure of hybrid macroH2A nucleosomes2fj7: Crystal structure of Nucleosome Core Particle Containing a Poly (dA.dT) Sequence Element2hio: HISTONE OCTAMER (CHICKEN), CHROMOSOMAL PROTEIN2nzd: Nucleosome core particle containing 145 bp of DNA  "},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/hist1h2bk-wikipedia\/#breadcrumbitem","name":"HIST1H2BK – Wikipedia"}}]}]