[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/hoxa7-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/hoxa7-wikipedia\/","headline":"HOXA7 – Wikipedia","name":"HOXA7 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Homeobox protein Hox-A7 is a protein","datePublished":"2019-01-15","dateModified":"2019-01-15","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/a\/ab\/PDB_1ahd_EBI.jpg\/180px-PDB_1ahd_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/a\/ab\/PDB_1ahd_EBI.jpg\/180px-PDB_1ahd_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/hoxa7-wikipedia\/","about":["Wiki"],"wordCount":6621,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensHomeobox protein Hox-A7 is a protein that in humans is encoded by the HOXA7 gene.[5][6][7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. For example, the encoded protein represses the transcription of differentiation-specific genes during keratinocyte proliferation, but this repression is then overcome by differentiation signals. This gene is highly similar to the antennapedia (Antp) gene of Drosophila.[7]Table of ContentsSee also[edit]References[edit]Further reading[edit]External links[edit]See also[edit]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000122592 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038236 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ McAlpine PJ, Shows TB (Aug 1990). “Nomenclature for human homeobox genes”. Genomics. 7 (3): 460. doi:10.1016\/0888-7543(90)90186-X. PMID\u00a01973146.^ Scott MP (Dec 1992). “Vertebrate homeobox gene nomenclature”. Cell. 71 (4): 551\u20133. doi:10.1016\/0092-8674(92)90588-4. PMID\u00a01358459. S2CID\u00a013370372.^ a b “Entrez Gene: HOXA7 homeobox A7”.Further reading[edit]ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}]]>Balling R, Mutter G, Gruss P, Kessel M (1989). “Craniofacial abnormalities induced by ectopic expression of the homeobox gene Hox-1.1 in transgenic mice”. Cell. 58 (2): 337\u201347. doi:10.1016\/0092-8674(89)90848-9. hdl:11858\/00-001M-0000-002C-3E33-1. PMID\u00a02568891. S2CID\u00a043658121.Acampora D, D’Esposito M, Faiella A,  et\u00a0al. (1990). “The human HOX gene family”. Nucleic Acids Res. 17 (24): 10385\u2013402. doi:10.1093\/nar\/17.24.10385. PMC\u00a0335308. PMID\u00a02574852.Boncinelli E, Acampora D, Pannese M,  et\u00a0al. (1990). “Organization of human class I homeobox genes”. Genome. 31 (2): 745\u201356. doi:10.1139\/g89-133. PMID\u00a02576652.Verlinsky Y, Morozov G, Gindilis V,  et\u00a0al. (1995). “Homeobox gene expression in human oocytes and preembryos”. Mol. Reprod. Dev. 41 (2): 127\u201332. doi:10.1002\/mrd.1080410202. PMID\u00a07654365. S2CID\u00a043123886.Apiou F, Flagiello D, Cillo C,  et\u00a0al. (1996). “Fine mapping of human HOX gene clusters”. Cytogenet. Cell Genet. 73 (1\u20132): 114\u20135. doi:10.1159\/000134320. PMID\u00a08646877.Knoepfler PS, Calvo KR, Chen H,  et\u00a0al. (1998). “Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1”. Proc. Natl. Acad. Sci. U.S.A. 94 (26): 14553\u20138. doi:10.1073\/pnas.94.26.14553. PMC\u00a025052. PMID\u00a09405651.Min W, Woo HJ, Lee CS,  et\u00a0al. (1998). “307-bp fragment in HOXA7 upstream sequence is sufficient for anterior boundary formation”. DNA Cell Biol. 17 (3): 293\u20139. doi:10.1089\/dna.1998.17.293. PMID\u00a09539109.McIlhatton MA, Bremner P, McMullin MF,  et\u00a0al. (1998). “Sequence characterisation and expression of homeobox HOX A7 in the multi-potential erythroleukaemic cell line TF-1”. Biochim. Biophys. Acta. 1442 (2\u20133): 329\u201333. doi:10.1016\/s0167-4781(98)00170-5. PMID\u00a09804983.Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). “Toward a complete human genome sequence”. Genome Res. 8 (11): 1097\u2013108. doi:10.1101\/gr.8.11.1097. PMID\u00a09847074.Dias Neto E, Correa RG, Verjovski-Almeida S,  et\u00a0al. (2000). “Shotgun sequencing of the human transcriptome with ORF expressed sequence tags”. Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491\u20136. Bibcode:2000PNAS…97.3491D. doi:10.1073\/pnas.97.7.3491. PMC\u00a016267. PMID\u00a010737800.Kim MH, Jin H, Seol EY,  et\u00a0al. (2000). “Sequence analysis and tissue specific expression of human HOXA7”. Mol. Biotechnol. 14 (1): 19\u201324. doi:10.1385\/MB:14:1:19. PMID\u00a010911612. S2CID\u00a025333474.La Celle PT, Polakowska RR (2001). “Human homeobox HOXA7 regulates keratinocyte transglutaminase type 1 and inhibits differentiation”. J. Biol. Chem. 276 (35): 32844\u201353. doi:10.1074\/jbc.M104598200. PMID\u00a011435435.Kosaki K, Kosaki R, Suzuki T,  et\u00a0al. (2002). “Complete mutation analysis panel of the 39 human HOX genes”. Teratology. 65 (2): 50\u201362. doi:10.1002\/tera.10009. PMID\u00a011857506.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Scherer SW, Cheung J, MacDonald JR,  et\u00a0al. (2003). “Human chromosome 7: DNA sequence and biology”. Science. 300 (5620): 767\u201372. Bibcode:2003Sci…300..767S. doi:10.1126\/science.1083423. PMC\u00a02882961. PMID\u00a012690205.Hillier LW, Fulton RS, Fulton LA,  et\u00a0al. (2003). “The DNA sequence of human chromosome 7”. Nature. 424 (6945): 157\u201364. Bibcode:2003Natur.424..157H. doi:10.1038\/nature01782. PMID\u00a012853948.Bertrand FE, Spengeman JD, Shah N, LeBien TW (2004). “B-cell development in the presence of the MLL\/AF4 oncoprotein proceeds in the absence of HOX A7 and HOX A9 expression”. Leukemia. 17 (12): 2454\u20139. doi:10.1038\/sj.leu.2403178. PMID\u00a014562113.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.li{counter-increment:listitem}.mw-parser-output .hlist ol>li::before{content:\" \"counter(listitem)\"a0 \"}.mw-parser-output .hlist dd ol>li:first-child::before,.mw-parser-output .hlist dt ol>li:first-child::before,.mw-parser-output .hlist li ol>li:first-child::before{content:\" (\"counter(listitem)\"a0 \"}]]>.navbox-abovebelow,.mw-parser-output tr+tr>.navbox-group,.mw-parser-output tr+tr>.navbox-image,.mw-parser-output tr+tr>.navbox-list{border-top:2px solid #fdfdfd}.mw-parser-output .navbox-title{background-color:#ccf}.mw-parser-output .navbox-abovebelow,.mw-parser-output .navbox-group,.mw-parser-output .navbox-subgroup .navbox-title{background-color:#ddf}.mw-parser-output .navbox-subgroup .navbox-group,.mw-parser-output .navbox-subgroup .navbox-abovebelow{background-color:#e6e6ff}.mw-parser-output .navbox-even{background-color:#f7f7f7}.mw-parser-output .navbox-odd{background-color:transparent}.mw-parser-output .navbox .hlist td dl,.mw-parser-output .navbox .hlist td ol,.mw-parser-output .navbox .hlist td ul,.mw-parser-output .navbox td.hlist dl,.mw-parser-output .navbox td.hlist ol,.mw-parser-output .navbox td.hlist ul{padding:0.125em 0}.mw-parser-output .navbox .navbar{display:block;font-size:100%}.mw-parser-output .navbox-title .navbar{float:left;text-align:left;margin-right:0.5em}]]>       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4span,.mw-parser-output .navbar a>abbr{text-decoration:inherit}.mw-parser-output .navbar-mini abbr{font-variant:small-caps;border-bottom:none;text-decoration:none;cursor:inherit}.mw-parser-output .navbar-ct-full{font-size:114%;margin:0 7em}.mw-parser-output .navbar-ct-mini{font-size:114%;margin:0 4em}]]>PDB gallery1ahd: DETERMINATION OF THE NMR SOLUTION STRUCTURE OF AN ANTENNAPEDIA HOMEODOMAIN-DNA COMPLEX1hom: DETERMINATION OF THE THREE-DIMENSIONAL STRUCTURE OF THE ANTENNAPEDIA HOMEODOMAIN FROM DROSOPHILA IN SOLUTION BY 1H NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY1san: THE DES(1-6)ANTENNAPEDIA HOMEODOMAIN: COMPARISON OF THE NMR SOLUTION STRUCTURE AND THE DNA BINDING AFFINITY WITH THE INTACT ANTENNAPEDIA HOMEODOMAINS) HOMEODOMAIN FROM NUCLEAR MAGNETIC RESONANCE DATA IN SOLUTION USING A NOVEL STRATEGY FOR THE STRUCTURE CALCULATION WITH THE PROGRAMS DIANA, CALIBA, HABAS AND GLOMSA”>"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/hoxa7-wikipedia\/#breadcrumbitem","name":"HOXA7 – Wikipedia"}}]}]