[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/kcnu1-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/kcnu1-wikipedia\/","headline":"KCNU1 – Wikipedia","name":"KCNU1 – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens Potassium channel, subfamily U, member 1, also known","datePublished":"2015-10-18","dateModified":"2015-10-18","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/kcnu1-wikipedia\/","wordCount":2871,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensPotassium channel, subfamily U, member 1, also known as KCNU1, is a gene encoding the KCa5.1 protein.[4]Although this channel is structurally related to the calcium-activated potassium channels, it cannot be classified as such since it is activated by high intracellular pH and relatively insensitive to changes in calcium concentrations.[5][6][7]References[edit]^ a b c GRCm38: Ensembl release 89: ENSMUSG00000031576 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Schreiber M, Wei A, Yuan A, Gaut J, Saito M, Salkoff L (February 1998). “Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes”. J. Biol. Chem. 273 (6): 3509\u201316. doi:10.1074\/jbc.273.6.3509. PMID\u00a09452476.^ Wei AD, Gutman GA, Aldrich R, Chandy KG, Grissmer S, Wulff H (2005). “International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels”. Pharmacol Rev. 57 (4): 463\u201372. doi:10.1124\/pr.57.4.9. PMID\u00a016382103. S2CID\u00a08290401.^ Zhang X, Zeng X, Xia XM, Lingle CJ (September 2006). “pH-regulated Slo3 K+ channels: properties of unitary currents”. J. Gen. Physiol. 128 (3): 301\u201315. doi:10.1085\/jgp.200609551. PMC\u00a02151565. PMID\u00a016940554.^ Zhang X, Zeng X, Lingle CJ (September 2006). “Slo3 K+ channels: voltage and pH dependence of macroscopic currents”. J. Gen. Physiol. 128 (3): 317\u201336. doi:10.1085\/jgp.200609552. PMC\u00a02151566. PMID\u00a016940555.Celia M. Santi, Alice Butler, Julia Kuhn, Aguan Wei, Lawrence Salkoff. Bovine and mouse SLO3 K+ channels: Evolutionary divergence points to a RCK1 region of critical function. J Biol Chem.284: 21589-98 (2009).External links[edit]Overview of all the structural information available in the PDB for UniProt: A8MYU2 (Potassium channel subfamily U member 1) at the PDBe-KB.Further reading[edit]Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2002). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Kimura K, Wakamatsu A, Suzuki Y,  et\u00a0al. (2006). “Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes”. Genome Res. 16 (1): 55\u201365. doi:10.1101\/gr.4039406. PMC\u00a01356129. PMID\u00a016344560.Schreiber M, Wei A, Yuan A,  et\u00a0al. (1998). “Slo3, a novel pH-sensitive K+ channel from mammalian spermatocytes”. J. Biol. Chem. 273 (6): 3509\u201316. doi:10.1074\/jbc.273.6.3509. PMID\u00a09452476.Nusbaum C, Mikkelsen TS, Zody MC,  et\u00a0al. (2006). “DNA sequence and analysis of human chromosome 8”. Nature. 439 (7074): 331\u20135. Bibcode:2006Natur.439..331N. doi:10.1038\/nature04406. PMID\u00a016421571.Wei AD, Gutman GA, Aldrich R,  et\u00a0al. (2005). “International Union of Pharmacology. LII. Nomenclature and molecular relationships of calcium-activated potassium channels”. Pharmacol. Rev. 57 (4): 463\u201372. doi:10.1124\/pr.57.4.9. PMID\u00a016382103. S2CID\u00a08290401.Celia M. Santi, Alice Butler, Julia Kuhn, Aguan Wei, Lawrence Salkoff.  Bovine and mouse SLO3 K+ channels: Evolutionary divergence points to a RCK1 region of critical function.  J Biol Chem.284: 21589-98 (2009).  "},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/kcnu1-wikipedia\/#breadcrumbitem","name":"KCNU1 – Wikipedia"}}]}]