[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/king-wai-yau-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/king-wai-yau-wikipedia\/","headline":"King-Wai Yau – Wikipedia","name":"King-Wai Yau – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Chinese-American neuroscientist King-Wai Yau (Chinese: \u6e38\u666f\u5a01; pinyin: Y\u00f3u J\u01d0ngw\u0113i; born October 27, 1948)","datePublished":"2016-08-17","dateModified":"2016-08-17","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/king-wai-yau-wikipedia\/","about":["Wiki"],"wordCount":4348,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Chinese-American neuroscientistKing-Wai Yau (Chinese: \u6e38\u666f\u5a01; pinyin: Y\u00f3u J\u01d0ngw\u0113i; born October 27, 1948) is a Chinese-born American neuroscientist and Professor of Neuroscience at Johns Hopkins University School of Medicine in Baltimore, Maryland.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Table of ContentsBiography[edit]Scientific contributions[edit]Selected honors & awards[edit]Highly-Cited Papers[edit]References[edit]External links[edit]Biography[edit]Born in Guangzhou (formerly called Canton), Guangdong, China, he was the sixth of seven children. His family relocated to Hong Kong within months of his birth. His father, a businessman, died when Yau was only five years old.He attended secondary school in Buddhist Wong Fung Ling College and St. Paul’s Co-educational College in Hong Kong, before entering University of Hong Kong Faculty of Medicine to study medicine. Not wanting to be a physician, however, he departed for the United States in 1968 after only one year of medical study. He received an A.B. in physics (University Scholar; Phi Beta Kappa) from Princeton in 1971 and a Ph.D. in neurobiology from Harvard in 1975, completing his doctoral thesis under John G. Nicholls, a former student of Bernard Katz. He did postdoctoral work with Denis A. Baylor at Stanford University, then with Sir Alan L. Hodgkin at University of Cambridge, United Kingdom. Thereafter, he was on the faculty of University of Texas Medical Branch at Galveston (1981\u201386), rising to Professor of Physiology and Biophysics in 1985. In 1986, he became Professor of Neuroscience and Investigator of Howard Hughes Medical Institute (1986-2004) at Johns Hopkins University School of Medicine, where he has been since.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Scientific contributions[edit]He is known for discoveries on how light and odor are sensed in the eye and the nose, triggering neural signals to be transmitted to the brain. He has greatly elucidated the properties of the light responses and their underlying phototransduction mechanisms in retinal rods and cones,[1] as well as in intrinsically-photosensitive retinal ganglion cells which express the photopigment, melanopsin, to mediate mostly non-image vision such as pupillary light reflex and photoentrainment of the circadian rhythm.[2] He has made similarly important discoveries on olfactory transduction in the receptor neurons of the nasal olfactory epithelium. His work impacts broadly on understanding G-protein signaling at a quantitative level. His investigations on the spontaneous activity of rod and cone pigments have provided a physicochemical explanation for why our vision does not extend into Infrared wavelengths.[3]He is a Member of the National Academy of Sciences and the National Academy of Medicine, and a Fellow of the American Academy of Arts and Sciences, as well as a Member of Academia Sinica, Taiwan.Selected honors & awards[edit]1978, Alfred P. Sloan Foundation Fellow1980, Visiting Fellow, Trinity College, Cambridge, United Kingdom1980, Rank Prize in Optoelectronics, The Rank Prize Funds, United Kingdom1993, Friedenwald Award,[4] Association for Research in Vision and Ophthalmology (ARVO)1994, Alcon Award in Vision Research, Alcon Research Institute1995, Fellow, American Academy of Arts and Sciences1996, Magnes Prize, Hebrew University of Jerusalem2004, Teacher of the Year, Johns Hopkins University School of Medicine2005, Alcon Award in Vision Research (second time), Alcon Research Institute2006, Balazs Prize, International Society for Eye Research (ISER)2008, Ant\u00f3nio Champalimaud Vision Award, The Champalimaud Foundation, Portugal2010, Member, National Academy of Sciences2012, CNIB Chanchlani Global Vision Research Award, Canada2013, Alexander Hollaender Award in Biophysics,[5]National Academy of Sciences2016, RRF Paul Kayser International Award for Retinal Research (ISER)2017, Daniel Nathans Scientific Innovator Award, Johns Hopkins University School of Medicine2018, Member, National Academy of Medicine2019, Helen Keller Prize for Vision Research, Helen Keller Foundation & BrightFocus Foundation2019, Beckman-Argyros Vision Award, Arnold & Mabel Beckman Foundation2022, Member, Academia Sinica, TaiwanHighly-Cited Papers[edit]Articles with over 500 citations according to Google Scholar [1] as of May 6, 2017:1979 “The membrane current of single rod outer segments”,[6] 607 citations1979 “Responses of retinal rods to single photons”,[7] 819 citations1989 “Cyclic GMP-activated conductance of retinal photoreceptor cells”,[8] 590 citations1990 “Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons”,[9] 672 citations1998 “Identification of ligands for olfactory receptors by functional expression of a receptor library”,[10] 534 citations2002 “Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity”,[2] 1579 citations2003 “Melanopsin and rod\u2013cone photoreceptive systems account for all major accessory visual functions in mice”,[11] 838 citations2003 “Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice”,[12] 608 citations2005 “Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN”,[13] 798 citations2006 “Central projections of melanopsin\u2010expressing retinal ganglion cells in the mouse”,[14] 518 citationsReferences[edit]^ Yau, KW (1994). “The Friedenwald Lecture: Phototransduction mechanism in retinal rods and cones”. Investigative Ophthalmology and Visual Science. 35: 9\u201332.^ a b Hattar, S; Liao HW; Takao M; Berson DM; Yau KW (2002). “Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity”. Science. 295 (5557): 1065\u20131070. Bibcode:2002Sci…295.1065H. doi:10.1126\/science.1069609. PMC\u00a02885915. PMID\u00a011834834.^ Luo, DG; Yue WWS; Ala-Laurila P; Yau KW (2011). “Activation of visual pigments by light and heat”. Science. 332 (6035): 1307\u20131312. Bibcode:2011Sci…332.1307L. doi:10.1126\/science.1200172. PMC\u00a04349410. PMID\u00a021659602.^ Baylor, D (1994). “Introduction of King-Wai Yau 1993 Friedenwald Award winner”. Investigative Ophthalmology and Visual Science. 35 (1): 6\u20138. PMID\u00a08300364.^ “National Academy of Sciences 2013 Awards”.^ Baylor DA, Lamb TD, Yau KW (1979). “The membrane current of single rod outer segments”. Journal of Physiology. 288: 589\u2013611. PMC\u00a01281446. PMID\u00a0112242.^ Baylor DA, Lamb TD, Yau KW (1979). “Responses of retinal rods to single photons”. Journal of Physiology. 288: 613\u2013634. doi:10.1113\/jphysiol.1979.sp012716. PMC\u00a01281447. PMID\u00a0112243.^ Yau KW, Baylor DA (1989). “Cyclic GMP-activated conductance of retinal photoreceptor cells”. Annual Review of Neuroscience. 12: 289\u2013327. doi:10.1146\/annurev.neuro.12.1.289. PMID\u00a02467600.^ Dhallan RS, Yau KW, Schrader KA, Reed RR (1990). “Primary structure and functional expression of a cyclic nucleotide-activated channel from olfactory neurons”. Nature. 347 (6289): 184\u2013187. Bibcode:1990Natur.347..184D. doi:10.1038\/347184a0. PMID\u00a01697649. S2CID\u00a04362106.^ Krautwurst D, Yau KW, Reed RR (1998). “Identification of ligands for olfactory receptors by functional expression of a receptor library”. Cell. 95 (7): 917\u2013926. doi:10.1016\/S0092-8674(00)81716-X. PMID\u00a09875846. S2CID\u00a015004227.^ Hattar S, Lucas RJ, Mrosovsky N, Thompson S, Douglas RH, Hankins MW, Lem J, Biel M, Hofmann F, Foster RG, Yau KW (2003). “Melanopsin and rod\u2013cone photoreceptive systems account for all major accessory visual functions in mice”. Nature. 424 (6944): 76\u201381. Bibcode:2003Natur.424…75H. doi:10.1038\/nature01761. PMC\u00a02885907. PMID\u00a012808468.^ Lucas RJ, Hattar S, Berson DM, Foster RG, Yau K-W (2003). “Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice”. Science. 299 (5604): 247\u2013249. Bibcode:2003Sci…299..245L. CiteSeerX\u00a010.1.1.1028.8525. doi:10.1126\/science.1077293. PMID\u00a012522249. S2CID\u00a046505800.{{cite journal}}:  CS1 maint: uses authors parameter (link)^ Dacey DM, Liao HW, Peterson BB, Robinson FR, Smith VC, Pokorny J, Yau KW (2005). “Melanopsin-expressing ganglion cells in primate retina signal colour and irradiance and project to the LGN”. Nature. 433 (7027): 749\u2013754. Bibcode:2005Natur.433..749D. doi:10.1038\/nature03387. PMID\u00a015716953. S2CID\u00a04401722.^ Hattar S, Kumar M, Park A, Tong P, Tung J, Yau K-W, Berson DM (2006). “Central projections of melanopsin\u2010expressing retinal ganglion cells in the mouse”. Journal of Comparative Neurology. 497 (3): 326\u2013349. doi:10.1002\/cne.20970. PMC\u00a02885916. PMID\u00a016736474.{{cite journal}}:  CS1 maint: uses authors parameter (link)External links[edit]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/king-wai-yau-wikipedia\/#breadcrumbitem","name":"King-Wai Yau – Wikipedia"}}]}]