[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/myocardin-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/myocardin-wikipedia\/","headline":"Myocardin – Wikipedia","name":"Myocardin – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Myocardin is a protein that in","datePublished":"2019-07-29","dateModified":"2019-07-29","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/myocardin-wikipedia\/","about":["Wiki"],"wordCount":4432,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensMyocardin is a protein that in humans is encoded by the MYOCD gene.[5][6][7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Myocardin is a smooth muscle and cardiac muscle-specific transcriptional coactivator of serum response factor. When expressed ectopically in nonmuscle cells, myocardin can induce smooth muscle differentiation by its association with serum response factor (SRF; MIM 600589).[supplied by OMIM][7]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000141052 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020542 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Wang D, Chang PS, Wang Z, Sutherland L, Richardson JA, Small E, Krieg PA, Olson EN (Jul 2001). “Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor”. Cell. 105 (7): 851\u201362. doi:10.1016\/S0092-8674(01)00404-4. PMID\u00a011439182. S2CID\u00a03762021.^ Wang DZ, Li S, Hockemeyer D, Sutherland L, Wang Z, Schratt G, Richardson JA, Nordheim A, Olson EN (Nov 2002). “Potentiation of serum response factor activity by a family of myocardin-related transcription factors”. Proc Natl Acad Sci U S A. 99 (23): 14855\u201360. Bibcode:2002PNAS…9914855W. doi:10.1073\/pnas.222561499. PMC\u00a0137508. PMID\u00a012397177.^ a b “Entrez Gene: MYOCD myocardin”.Further reading[edit]Du KL, Ip HS, Li J,  et\u00a0al. (2003). “Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation”. Mol. Cell. Biol. 23 (7): 2425\u201337. doi:10.1128\/MCB.23.7.2425-2437.2003. PMC\u00a0150745. PMID\u00a012640126.Wang Z, Wang DZ, Pipes GC, Olson EN (2003). “Myocardin is a master regulator of smooth muscle gene expression”. Proc. Natl. Acad. Sci. U.S.A. 100 (12): 7129\u201334. Bibcode:2003PNAS..100.7129W. doi:10.1073\/pnas.1232341100. PMC\u00a0165841. PMID\u00a012756293.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Du KL, Chen M, Li J,  et\u00a0al. (2004). “Megakaryoblastic leukemia factor-1 transduces cytoskeletal signals and induces smooth muscle cell differentiation from undifferentiated embryonic stem cells”. J. Biol. Chem. 279 (17): 17578\u201386. doi:10.1074\/jbc.M400961200. PMID\u00a014970199.Wang Z, Wang DZ, Hockemeyer D,  et\u00a0al. (2004). “Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression”. Nature. 428 (6979): 185\u20139. Bibcode:2004Natur.428..185W. doi:10.1038\/nature02382. PMID\u00a015014501. S2CID\u00a04408041.van Tuyn J, Kna\u00e4n-Shanzer S, van de Watering MJ,  et\u00a0al. (2006). “Activation of cardiac and smooth muscle-specific genes in primary human cells after forced expression of human myocardin”. Cardiovasc. Res. 67 (2): 245\u201355. doi:10.1016\/j.cardiores.2005.04.013. PMID\u00a015907818.Liu ZP, Wang Z, Yanagisawa H, Olson EN (2005). “Phenotypic modulation of smooth muscle cells through interaction of Foxo4 and myocardin”. Dev. Cell. 9 (2): 261\u201370. doi:10.1016\/j.devcel.2005.05.017. PMID\u00a016054032.Doi H, Iso T, Yamazaki M,  et\u00a0al. (2006). “HERP1 inhibits myocardin-induced vascular smooth muscle cell differentiation by interfering with SRF binding to CArG box”. Arterioscler. Thromb. Vasc. Biol. 25 (11): 2328\u201334. doi:10.1161\/01.ATV.0000185829.47163.32. PMID\u00a016151017.Zody MC, Garber M, Adams DJ,  et\u00a0al. (2006). “DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage”. Nature. 440 (7087): 1045\u20139. Bibcode:2006Natur.440.1045Z. doi:10.1038\/nature04689. PMC\u00a02610434. PMID\u00a016625196.Chow N, Bell RD, Deane R,  et\u00a0al. (2007). “Serum response factor and myocardin mediate arterial hypercontractility and cerebral blood flow dysregulation in Alzheimer’s phenotype”. Proc. Natl. Acad. Sci. U.S.A. 104 (3): 823\u20138. Bibcode:2007PNAS..104..823C. doi:10.1073\/pnas.0608251104. PMC\u00a01783398. PMID\u00a017215356.Milyavsky M, Shats I, Cholostoy A,  et\u00a0al. (2007). “Inactivation of myocardin and p16 during malignant transformation contributes to a differentiation defect”. Cancer Cell. 11 (2): 133\u201346. doi:10.1016\/j.ccr.2006.11.022. PMID\u00a017292825.Li HJ, Haque Z, Lu Q,  et\u00a0al. (2007). “Steroid receptor coactivator 3 is a coactivator for myocardin, the regulator of smooth muscle transcription and differentiation”. Proc. Natl. Acad. Sci. U.S.A. 104 (10): 4065\u201370. Bibcode:2007PNAS..104.4065L. doi:10.1073\/pnas.0611639104. PMC\u00a01820709. PMID\u00a017360478.Pijnappels DA, van Tuyn J, de Vries AA,  et\u00a0al. (2007). “Resynchronization of separated rat cardiomyocyte fields with genetically modified human ventricular scar fibroblasts”. Circulation. 116 (18): 2018\u201328. doi:10.1161\/CIRCULATIONAHA.107.712935. PMID\u00a017938287.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/myocardin-wikipedia\/#breadcrumbitem","name":"Myocardin – Wikipedia"}}]}]