[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/nav1-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/nav1-wikipedia\/","headline":"NAV1 – Wikipedia","name":"NAV1 – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens Neuron navigator 1 is a protein that in","datePublished":"2017-06-19","dateModified":"2017-06-19","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/nav1-wikipedia\/","about":["Wiki"],"wordCount":3070,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensNeuron navigator 1 is a protein that in humans is encoded by the NAV1 gene.[5][6][7]This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known.[7]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000134369 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000009418 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Maes T, Barcelo A, Buesa C (Jun 2002). “Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans”. Genomics. 80 (1): 21\u201330. doi:10.1006\/geno.2002.6799. PMID\u00a012079279.^ Coy JF, Wiemann S, Bechmann I, Bachner D, Nitsch R, Kretz O, Christiansen H, Poustka A (Jun 2002). “Pore membrane and\/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms”. Gene. 290 (1\u20132): 73\u201394. doi:10.1016\/S0378-1119(02)00567-X. PMID\u00a012062803.^ a b “Entrez Gene: NAV1 neuron navigator 1”.Further reading[edit]Kimura K, Wakamatsu A, Suzuki Y,  et\u00a0al. (2006). “Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes”. Genome Res. 16 (1): 55\u201365. doi:10.1101\/gr.4039406. PMC\u00a01356129. PMID\u00a016344560.Peeters PJ, Baker A, Goris I,  et\u00a0al. (2004). “Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53”. Brain Res. Dev. Brain Res. 150 (2): 89\u2013101. doi:10.1016\/j.devbrainres.2004.03.004. PMID\u00a015158073.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Okazaki N, Kikuno R, Ohara R,  et\u00a0al. (2003). “Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries”. DNA Res. 10 (1): 35\u201348. doi:10.1093\/dnares\/10.1.35. PMID\u00a012693553.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Nakayama M, Kikuno R, Ohara O (2003). “Protein\u2013Protein Interactions Between Large Proteins: Two-Hybrid Screening Using a Functionally Classified Library Composed of Long cDNAs”. Genome Res. 12 (11): 1773\u201384. doi:10.1101\/gr.406902. PMC\u00a0187542. PMID\u00a012421765.Nagase T, Ishikawa K, Kikuno R,  et\u00a0al. (2000). “Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro”. DNA Res. 6 (5): 337\u201345. doi:10.1093\/dnares\/6.5.337. PMID\u00a010574462.Hirosawa M, Nagase T, Ishikawa K,  et\u00a0al. (2000). “Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain”. DNA Res. 6 (5): 329\u201336. doi:10.1093\/dnares\/6.5.329. PMID\u00a010574461.  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