[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/prl-8-53-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/prl-8-53-wikipedia\/","headline":"PRL-8-53 – Wikipedia","name":"PRL-8-53 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Chemical compound PRL-8-53 is a nootropic research chemical derived from benzoic acid and","datePublished":"2017-09-11","dateModified":"2017-09-11","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/prl-8-53-wikipedia\/","wordCount":1055,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Chemical compoundPRL-8-53 is a nootropic research chemical derived from benzoic acid and phenylmethylamine (Benzylamine) that has been shown to act as a hypermnesic drug in humans; it was first synthesized by medical chemistry professor Nikolaus Hansl at Creighton University in the 1970s as part of his work on amino ethyl meta benzoic acid esters.[1][2]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Table of ContentsNootropic effects[edit]Mechanism of action[edit]Toxicity[edit]Reasons for discontinuation[edit]Hansl v. Creighton University[edit]Patent[edit]Synonyms[edit]See also[edit]References[edit]Nootropic effects[edit]PRL-8-53 is not a medical treatment for disease or illness, although a nootropic effect in healthy individuals has been claimed. A single double-blind trial exploring the effects of PRL-8-53 in 47 healthy volunteers on various cognitive tasks remains the only human trial of PRL-8-53 to date. In the study, 5\u00a0mg of the drug was administered orally 2\u20132.5 hours before study tasks.[1] Overall improvements in recollection differed between subject groups when compared to their respective placebo scores. Poorer performers (six words or fewer) showed an 87.5-105% increase in recollection while higher performers (eight or more words) exhibited a smaller 7.9-14% increase that failed to reach statistical significance. Older subjects (       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/prl-8-53-wikipedia\/#breadcrumbitem","name":"PRL-8-53 – Wikipedia"}}]}]