[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/s1pr3-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/s1pr3-wikipedia\/","headline":"S1PR3 – Wikipedia","name":"S1PR3 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein and coding gene in humans Sphingosine-1-phosphate receptor 3 also known as S1PR3","datePublished":"2017-06-14","dateModified":"2017-06-14","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/s1pr3-wikipedia\/","wordCount":3728,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein and coding gene in humansSphingosine-1-phosphate receptor 3 also known as S1PR3 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).  Hence this receptor is also known as S1P3.[5]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Table of ContentsFunction[edit]See also[edit]References[edit]Further reading[edit]External links[edit]Function[edit]This gene encodes a member of the EDG family of receptors, which are G protein-coupled receptors. This protein has been identified as a functional receptor for sphingosine 1-phosphate and likely contributes to the regulation of angiogenesis and vascular endothelial cell function.[5]See also[edit]References[edit]Further reading[edit]Hla T, Lee MJ, Ancellin N,  et\u00a0al. (2000). “Sphingosine-1-phosphate signaling via the EDG-1 family of G-protein-coupled receptors”. Ann. N. Y. Acad. Sci. 905 (1): 16\u201324. Bibcode:2000NYASA.905…16H. doi:10.1111\/j.1749-6632.2000.tb06534.x. PMID\u00a010818438. S2CID\u00a019435541.Spiegel S (2000). “Sphingosine 1-phosphate: a ligand for the EDG-1 family of G-protein-coupled receptors”. Ann. N. Y. Acad. Sci. 905 (1): 54\u201360. Bibcode:2000NYASA.905…54S. doi:10.1111\/j.1749-6632.2000.tb06537.x. PMID\u00a010818441. S2CID\u00a09257870.Watsky MA, Griffith M, Wang DA, Tigyi GJ (2000). “Phospholipid growth factors and corneal wound healing”. Ann. N. Y. Acad. Sci. 905 (1): 142\u201358. Bibcode:2000NYASA.905..142W. doi:10.1111\/j.1749-6632.2000.tb06546.x. PMID\u00a010818450. S2CID\u00a09789496.Takuwa Y (2002). “[Regulation of Rho family G proteins and cell motility by the Edg family of sphingosin 1-phosphate receptors]”. Tanpakushitsu Kakusan Koso. 47 (4 Suppl): 496\u2013502. PMID\u00a011915348.Van Koppen CJ, Meyer Zu Heringdorf D, Zhang C,  et\u00a0al. (1996). “A distinct G(i) protein-coupled receptor for sphingosylphosphorylcholine in human leukemia HL-60 cells and human neutrophils”. Mol. Pharmacol. 49 (6): 956\u201361. PMID\u00a08649355.Yamaguchi F, Tokuda M, Hatase O, Brenner S (1996). “Molecular cloning of the novel human G protein-coupled receptor (GPCR) gene mapped on chromosome 9”. Biochem. Biophys. Res. Commun. 227 (2): 608\u201314. doi:10.1006\/bbrc.1996.1553. PMID\u00a08878560.An S, Bleu T, Huang W,  et\u00a0al. (1998). “Identification of cDNAs encoding two G protein-coupled receptors for lysosphingolipids”. FEBS Lett. 417 (3): 279\u201382. doi:10.1016\/S0014-5793(97)01301-X. PMID\u00a09409733. S2CID\u00a026300053.Van Brocklyn JR, Tu Z, Edsall LC,  et\u00a0al. (1999). “Sphingosine 1-phosphate-induced cell rounding and neurite retraction are mediated by the G protein-coupled receptor H218”. J. Biol. Chem. 274 (8): 4626\u201332. doi:10.1074\/jbc.274.8.4626. PMID\u00a09988698.Zhang Q, Peyruchaud O, French KJ,  et\u00a0al. (1999). “Sphingosine 1-phosphate stimulates fibronectin matrix assembly through a Rho-dependent signal pathway”. Blood. 93 (9): 2984\u201390. doi:10.1182\/blood.V93.9.2984. PMID\u00a010216094.Ancellin N, Hla T (1999). “Differential pharmacological properties and signal transduction of the sphingosine 1-phosphate receptors EDG-1, EDG-3, and EDG-5”. J. Biol. Chem. 274 (27): 18997\u20139002. doi:10.1074\/jbc.274.27.18997. PMID\u00a010383399.Windh RT, Lee MJ, Hla T,  et\u00a0al. (1999). “Differential coupling of the sphingosine 1-phosphate receptors Edg-1, Edg-3, and H218\/Edg-5 to the G(i), G(q), and G(12) families of heterotrimeric G proteins”. J. Biol. Chem. 274 (39): 27351\u20138. doi:10.1074\/jbc.274.39.27351. PMID\u00a010488065.Goetzl EJ, Dolezalova H, Kong Y,  et\u00a0al. (1999). “Distinctive expression and functions of the type 4 endothelial differentiation gene-encoded G protein-coupled receptor for lysophosphatidic acid in ovarian cancer”. Cancer Res. 59 (20): 5370\u20135. PMID\u00a010537322.Lee MJ, Thangada S, Claffey KP,  et\u00a0al. (1999). “Vascular endothelial cell adherens junction assembly and morphogenesis induced by sphingosine-1-phosphate”. Cell. 99 (3): 301\u201312. doi:10.1016\/S0092-8674(00)81661-X. PMID\u00a010555146. S2CID\u00a01126846.An S, Zheng Y, Bleu T (2000). “Sphingosine 1-phosphate-induced cell proliferation, survival, and related signaling events mediated by G protein-coupled receptors Edg3 and Edg5”. J. Biol. Chem. 275 (1): 288\u201396. doi:10.1074\/jbc.275.1.288. PMID\u00a010617617.Orlati S, Porcelli AM, Hrelia S,  et\u00a0al. (2000). “Sphingosine-1-phosphate activates phospholipase D in human airway epithelial cells via a G protein-coupled receptor”. Arch. Biochem. Biophys. 375 (1): 69\u201377. doi:10.1006\/abbi.1999.1589. PMID\u00a010683250.Lee H, Goetzl EJ, An S (2000). “Lysophosphatidic acid and sphingosine 1-phosphate stimulate endothelial cell wound healing”. Am. J. Physiol., Cell Physiol. 278 (3): C612\u20138. doi:10.1152\/ajpcell.2000.278.3.C612. PMID\u00a010712250. S2CID\u00a010976499.Kimura T, Watanabe T, Sato K,  et\u00a0al. (2000). “Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3”. Biochem. J. 348 (1): 71\u20136. doi:10.1042\/0264-6021:3480071. PMC\u00a01221037. PMID\u00a010794715.External links[edit]This article incorporates text from the United States National Library of Medicine, which is in the public domain.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/s1pr3-wikipedia\/#breadcrumbitem","name":"S1PR3 – Wikipedia"}}]}]