[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/taok1-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/taok1-wikipedia\/","headline":"TAOK1 – Wikipedia","name":"TAOK1 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Serine\/threonine-protein kinase TAO1 is an enzyme","datePublished":"2022-08-21","dateModified":"2022-08-21","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/taok1-wikipedia\/","about":["Wiki"],"wordCount":4421,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensSerine\/threonine-protein kinase TAO1 is an enzyme that in humans is encoded by the TAOK1 gene.[5][6][7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Clinical significance[edit]Mutations of the TAOK1 gene cause developmental delay with or without intellectual impairment or behavioral abnormalities (DDIB), a condition first described in 2019.References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000160551 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000017291 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O (Apr 2000). “Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro”. DNA Res. 7 (1): 65\u201373. doi:10.1093\/dnares\/7.1.65. PMID\u00a010718198.^ Timm T, Li XY, Biernat J, Jiao J, Mandelkow E, Vandekerckhove J, Mandelkow EM (Sep 2003). “MARKK, a Ste20-like kinase, activates the polarity-inducing kinase MARK\/PAR-1”. EMBO J. 22 (19): 5090\u2013101. doi:10.1093\/emboj\/cdg447. PMC\u00a0204455. PMID\u00a014517247.^ “Entrez Gene: TAOK1 TAO kinase 1”.Further reading[edit]Hutchison M, Berman KS, Cobb MH (1998). “Isolation of TAO1, a protein kinase that activates MEKs in stress-activated protein kinase cascades”. J. Biol. Chem. 273 (44): 28625\u201332. doi:10.1074\/jbc.273.44.28625. PMID\u00a09786855.Chen Z, Hutchison M, Cobb MH (1999). “Isolation of the protein kinase TAO2 and identification of its mitogen-activated protein kinase\/extracellular signal-regulated kinase kinase binding domain”. J. Biol. Chem. 274 (40): 28803\u20137. doi:10.1074\/jbc.274.40.28803. PMID\u00a010497253.Dias Neto E, Correa RG, Verjovski-Almeida S,  et\u00a0al. (2000). “Shotgun sequencing of the human transcriptome with ORF expressed sequence tags”. Proc. Natl. Acad. Sci. U.S.A. 97 (7): 3491\u20136. Bibcode:2000PNAS…97.3491D. doi:10.1073\/pnas.97.7.3491. PMC\u00a016267. PMID\u00a010737800.Wistow G, Bernstein SL, Wyatt MK,  et\u00a0al. (2002). “Expressed sequence tag analysis of human RPE\/choroid for the NEIBank Project: over 6000 non-redundant transcripts, novel genes and splice variants”. Mol. Vis. 8: 205\u201320. PMID\u00a012107410.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Yustein JT, Xia L, Kahlenburg JM,  et\u00a0al. (2003). “Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38”. Oncogene. 22 (40): 6129\u201341. doi:10.1038\/sj.onc.1206605. PMID\u00a013679851.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Lizcano JM, G\u00f6ransson O, Toth R,  et\u00a0al. (2005). “LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK\/PAR-1”. EMBO J. 23 (4): 833\u201343. doi:10.1038\/sj.emboj.7600110. PMC\u00a0381014. PMID\u00a014976552.Beausoleil SA, Jedrychowski M, Schwartz D,  et\u00a0al. (2004). “Large-scale characterization of HeLa cell nuclear phosphoproteins”. Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130\u20135. Bibcode:2004PNAS..10112130B. doi:10.1073\/pnas.0404720101. PMC\u00a0514446. PMID\u00a015302935.Zihni C, Mitsopoulos C, Tavares IA,  et\u00a0al. (2006). “Prostate-derived sterile 20-like kinase 2 (PSK2) regulates apoptotic morphology via C-Jun N-terminal kinase and Rho kinase-1”. J. Biol. Chem. 281 (11): 7317\u201323. doi:10.1074\/jbc.M513769200. PMID\u00a016407310.Beausoleil SA, Vill\u00e9n J, Gerber SA,  et\u00a0al. (2006). “A probability-based approach for high-throughput protein phosphorylation analysis and site localization”. Nat. Biotechnol. 24 (10): 1285\u201392. doi:10.1038\/nbt1240. PMID\u00a016964243. S2CID\u00a014294292.Olsen JV, Blagoev B, Gnad F,  et\u00a0al. (2006). “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks”. Cell. 127 (3): 635\u201348. doi:10.1016\/j.cell.2006.09.026. PMID\u00a017081983. S2CID\u00a07827573.Raman M, Earnest S, Zhang K,  et\u00a0al. (2007). “TAO kinases mediate activation of p38 in response to DNA damage”. EMBO J. 26 (8): 2005\u201314. doi:10.1038\/sj.emboj.7601668. PMC\u00a01852793. PMID\u00a017396146.Draviam VM, Stegmeier F, Nalepa G,  et\u00a0al. (2007). “A functional genomic screen identifies a role for TAO1 kinase in spindle-checkpoint signalling”. Nat. Cell Biol. 9 (5): 556\u201364. doi:10.1038\/ncb1569. PMID\u00a017417629. S2CID\u00a034976750.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/taok1-wikipedia\/#breadcrumbitem","name":"TAOK1 – Wikipedia"}}]}]