[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/tomm22-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/tomm22-wikipedia\/","headline":"TOMM22 – Wikipedia","name":"TOMM22 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Mitochondrial import receptor subunit TOM22 homolog","datePublished":"2014-06-19","dateModified":"2014-06-19","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/tomm22-wikipedia\/","wordCount":4348,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensMitochondrial import receptor subunit TOM22 homolog is a protein that in humans is encoded by the TOMM22 gene.[5][6][7]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4The protein encoded by this gene is an integral membrane protein of the mitochondrial outer membrane. The encoded protein interacts with TOMM20 and TOMM40, and forms a complex with several other proteins to import cytosolic preproteins into the mitochondrion.[7]See also[edit]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000100216 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022427 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Yano M, Hoogenraad N, Terada K, Mori M (Oct 2000). “Identification and functional analysis of human Tom22 for protein import into mitochondria”. Mol Cell Biol. 20 (19): 7205\u201313. doi:10.1128\/MCB.20.19.7205-7213.2000. PMC\u00a086274. PMID\u00a010982837.^ Saeki K, Suzuki H, Tsuneoka M, Maeda M, Iwamoto R, Hasuwa H, Shida S, Takahashi T, Sakaguchi M, Endo T, Miura Y, Mekada E, Mihara K (Nov 2000). “Identification of mammalian TOM22 as a subunit of the preprotein translocase of the mitochondrial outer membrane”. J Biol Chem. 275 (41): 31996\u20132002. doi:10.1074\/jbc.M004794200. PMID\u00a010900208.^ a b “Entrez Gene: TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)”.Further reading[edit]Maruyama K, Sugano S (1994). “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1\u20132): 171\u20134. doi:10.1016\/0378-1119(94)90802-8. PMID\u00a08125298.Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K,  et\u00a0al. (1997). “Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library”. Gene. 200 (1\u20132): 149\u201356. doi:10.1016\/S0378-1119(97)00411-3. PMID\u00a09373149.Suzuki H, Okazawa Y, Komiya T,  et\u00a0al. (2001). “Characterization of rat TOM40, a central component of the preprotein translocase of the mitochondrial outer membrane”. J. Biol. Chem. 275 (48): 37930\u20136. doi:10.1074\/jbc.M006558200. PMID\u00a010980201.Johnston AJ, Hoogenraad J, Dougan DA,  et\u00a0al. (2003). “Insertion and assembly of human tom7 into the preprotein translocase complex of the outer mitochondrial membrane”. J. Biol. Chem. 277 (44): 42197\u2013204. doi:10.1074\/jbc.M205613200. PMID\u00a012198123.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Yano M, Terada K, Mori M (2003). “AIP is a mitochondrial import mediator that binds to both import receptor Tom20 and preproteins”. J. Cell Biol. 163 (1): 45\u201356. doi:10.1083\/jcb.200305051. PMC\u00a02173431. PMID\u00a014557246.Yano M, Terada K, Mori M (2004). “Mitochondrial import receptors Tom20 and Tom22 have chaperone-like activity”. J. Biol. Chem. 279 (11): 10808\u201313. doi:10.1074\/jbc.M311710200. PMID\u00a014699115.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Collins JE, Wright CL, Edwards CA,  et\u00a0al. (2005). “A genome annotation-driven approach to cloning the human ORFeome”. Genome Biol. 5 (10): R84. doi:10.1186\/gb-2004-5-10-r84. PMC\u00a0545604. PMID\u00a015461802.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.Humphries AD, Streimann IC, Stojanovski D,  et\u00a0al. (2005). “Dissection of the mitochondrial import and assembly pathway for human Tom40”. J. Biol. Chem. 280 (12): 11535\u201343. doi:10.1074\/jbc.M413816200. PMID\u00a015644312.Rual JF, Venkatesan K, Hao T,  et\u00a0al. (2005). “Towards a proteome-scale map of the human protein-protein interaction network”. Nature. 437 (7062): 1173\u20138. Bibcode:2005Natur.437.1173R. doi:10.1038\/nature04209. PMID\u00a016189514. S2CID\u00a04427026.Olsen JV, Blagoev B, Gnad F,  et\u00a0al. (2006). “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks”. Cell. 127 (3): 635\u201348. doi:10.1016\/j.cell.2006.09.026. PMID\u00a017081983.Bellot G, Cartron PF, Er E,  et\u00a0al. (2007). “TOM22, a core component of the mitochondria outer membrane protein translocation pore, is a mitochondrial receptor for the proapoptotic protein Bax”. Cell Death Differ. 14 (4): 785\u201394. doi:10.1038\/sj.cdd.4402055. 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