[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/trna-adenine58-n1-methyltransferase-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/trna-adenine58-n1-methyltransferase-wikipedia\/","headline":"TRNA (adenine58-N1)-methyltransferase – Wikipedia","name":"TRNA (adenine58-N1)-methyltransferase – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 TRNA (adenine58-N1)-methyltransferase (EC 2.1.1.220, tRNA m1A58 methyltransferase, tRNA (m1A58) methyltransferase, TrmI, tRNA (m1A58)","datePublished":"2016-10-04","dateModified":"2016-10-04","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/wikimedia.org\/api\/rest_v1\/media\/math\/render\/svg\/1c37b981df851b9e54e489e017b1481e37d418f3","url":"https:\/\/wikimedia.org\/api\/rest_v1\/media\/math\/render\/svg\/1c37b981df851b9e54e489e017b1481e37d418f3","height":"","width":""},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/trna-adenine58-n1-methyltransferase-wikipedia\/","wordCount":2650,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4TRNA (adenine58-N1)-methyltransferase (EC 2.1.1.220, tRNA m1A58 methyltransferase, tRNA (m1A58) methyltransferase, TrmI, tRNA (m1A58) Mtase, Rv2118cp, Gcd10p-Gcd14p, Trm61p-Trm6p) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA (adenine58-N1)-methyltransferase.[1][2][3] This enzyme catalyses the following chemical reactionS-adenosyl-L-methionine + adenine58 in tRNA        (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4\u21cc{displaystyle rightleftharpoons } S-adenosyl-L-homocysteine + N1-methyladenine58 in tRNAThe enzyme specifically methylates adenine58 in tRNA.References[edit]^ Droogmans L, Roovers M, Bujnicki JM, Tricot C, Hartsch T, Stalon V, Grosjean H (April 2003). “Cloning and characterization of tRNA (m1A58) methyltransferase (TrmI) from Thermus thermophilus HB27, a protein required for cell growth at extreme temperatures”. Nucleic Acids Research. 31 (8): 2148\u201356. doi:10.1093\/nar\/gkg314. PMC\u00a0153742. PMID\u00a012682365.^ Varshney U, Ramesh V, Madabushi A, Gaur R, Subramanya HS, RajBhandary UL (2004). “Mycobacterium tuberculosis Rv2118c codes for a single-component homotetrameric m1A58 tRNA methyltransferase”. Nucleic Acids Research. 32 (3): 1018\u201327. doi:10.1093\/nar\/gkh207. PMC\u00a0373377. PMID\u00a014960715.^ Anderson J, Phan L, Hinnebusch AG (May 2000). “The Gcd10p\/Gcd14p complex is the essential two-subunit tRNA(1-methyladenosine) methyltransferase of Saccharomyces cerevisiae”. Proceedings of the National Academy of Sciences of the United States of America. 97 (10): 5173\u20138. doi:10.1073\/pnas.090102597. PMC\u00a025801. 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