[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/vr-rna-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/vr-rna-wikipedia\/","headline":"VR-RNA – Wikipedia","name":"VR-RNA – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 In molecular biology, VR-RNA is a small RNA produced by Clostridium perfringens. It","datePublished":"2017-05-27","dateModified":"2017-05-27","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/vr-rna-wikipedia\/","wordCount":3902,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4In molecular biology, VR-RNA is a small RNA produced by Clostridium perfringens. It functions as a regulator of the two-component VirR\/VirS system.[1][2]VR-RNA regulates numerous genes including:       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4VR-RNA regulates the toxin colA (collagenase)  by base-pairing to colA mRNA, the 3\u2032 end of VR-RNA base-pairs to a region in the 5\u2032UTR of the colA mRNA. This induces cleavage of the colA mRNA in the 5\u2032 UTR and leads to stabilisation of the mRNA and increased translation.[17]See also[edit]References[edit]^ Shimizu, T; Yaguchi, H; Ohtani, K; Banu, S; Hayashi, H (Jan 2002). “Clostridial VirR\/VirS regulon involves a regulatory RNA molecule for expression of toxins”. Molecular Microbiology. 43 (1): 257\u2013265. doi:10.1046\/j.1365-2958.2002.02743.x. PMID\u00a011849553.^ Ohtani, K; Kawsar, HI; Okumura, K; Hayashi, H; Shimizu, T (May 16, 2003). “The VirR\/VirS regulatory cascade affects transcription of plasmid-encoded putative virulence genes in Clostridium perfringens strain 13”. FEMS Microbiology Letters. 222 (1): 137\u2013141. doi:10.1016\/s0378-1097(03)00255-6. PMID\u00a012757957.^ Shimizu, T; Yaguchi, H; Ohtani, K; Banu, S; Hayashi, H (Jan 2002). “Clostridial VirR\/VirS regulon involves a regulatory RNA molecule for expression of toxins”. Molecular Microbiology. 43 (1): 257\u2013265. doi:10.1046\/j.1365-2958.2002.02743.x. PMID\u00a011849553.^ Ohtani, K; Kawsar, HI; Okumura, K; Hayashi, H; Shimizu, T (May 16, 2003). “The VirR\/VirS regulatory cascade affects transcription of plasmid-encoded putative virulence genes in Clostridium perfringens strain 13”. FEMS Microbiology Letters. 222 (1): 137\u2013141. doi:10.1016\/s0378-1097(03)00255-6. PMID\u00a012757957.^ Ohtani, K; Hirakawa, H; Tashiro, K; Yoshizawa, S; Kuhara, S; Shimizu, T (Jun 2010). “Identification of a two-component VirR\/VirS regulon in Clostridium perfringens”. Anaerobe. 16 (3): 258\u2013264. doi:10.1016\/j.anaerobe.2009.10.003. PMID\u00a019835966.^ Ohtani, K; Hirakawa, H; Tashiro, K; Yoshizawa, S; Kuhara, S; Shimizu, T (Jun 2010). “Identification of a two-component VirR\/VirS regulon in Clostridium perfringens”. Anaerobe. 16 (3): 258\u2013264. doi:10.1016\/j.anaerobe.2009.10.003. PMID\u00a019835966.^ Ohtani, K; Kawsar, HI; Okumura, K; Hayashi, H; Shimizu, T (May 16, 2003). “The VirR\/VirS regulatory cascade affects transcription of plasmid-encoded putative virulence genes in Clostridium perfringens strain 13”. FEMS Microbiology Letters. 222 (1): 137\u2013141. doi:10.1016\/s0378-1097(03)00255-6. PMID\u00a012757957.^ Okumura, K; Kawsar, HI; Shimizu, T; Ohta, T; Hayashi, H; Shimizu, T (Jan 15, 2005). “Identification and characterization of a cell-wall anchored DNase gene in Clostridium perfringens”. FEMS Microbiology Letters. 242 (2): 281\u2013285. doi:10.1016\/j.femsle.2004.11.019. PMID\u00a015621449.^ Wang, R; Ohtani, K; Wang, Y; Yuan, Y; Hassan, S; Shimizu, T (Jan 2010). “Genetic and biochemical analysis of a class C non-specific acid phosphatase (NSAP) of Clostridium perfringens”. Microbiology. 156 (Pt 1): 167\u2013173. doi:10.1099\/mic.0.030395-0. PMID\u00a019833778.^ Ohtani, K; Hirakawa, H; Tashiro, K; Yoshizawa, S; Kuhara, S; Shimizu, T (Jun 2010). “Identification of a two-component VirR\/VirS regulon in Clostridium perfringens”. Anaerobe. 16 (3): 258\u2013264. doi:10.1016\/j.anaerobe.2009.10.003. PMID\u00a019835966.^ Hassan, S; Ohtani, K; Wang, R; Yuan, Y; Wang, Y; Yamaguchi, Y; Shimizu, T (Feb 2010). “Transcriptional regulation of hemO encoding heme oxygenase in Clostridium perfringens”. Journal of Microbiology (Seoul, Korea). 48 (1): 96\u2013101. doi:10.1007\/s12275-009-0384-3. PMID\u00a020221736. S2CID\u00a025990716.^ Ohtani, K; Hirakawa, H; Tashiro, K; Yoshizawa, S; Kuhara, S; Shimizu, T (Jun 2010). “Identification of a two-component VirR\/VirS regulon in Clostridium perfringens”. Anaerobe. 16 (3): 258\u2013264. doi:10.1016\/j.anaerobe.2009.10.003. PMID\u00a019835966.^ Ohtani, K; Hirakawa, H; Tashiro, K; Yoshizawa, S; Kuhara, S; Shimizu, T (Jun 2010). “Identification of a two-component VirR\/VirS regulon in Clostridium perfringens”. Anaerobe. 16 (3): 258\u2013264. doi:10.1016\/j.anaerobe.2009.10.003. PMID\u00a019835966.^ Ohtani, K; Hirakawa, H; Tashiro, K; Yoshizawa, S; Kuhara, S; Shimizu, T (Jun 2010). “Identification of a two-component VirR\/VirS regulon in Clostridium perfringens”. Anaerobe. 16 (3): 258\u2013264. doi:10.1016\/j.anaerobe.2009.10.003. PMID\u00a019835966.^ Yuan, Y; Ohtani, K; Yoshizawa, S; Shimizu, T (Feb 2012). “Complex transcriptional regulation of citrate metabolism in Clostridium perfringens”. Anaerobe. 18 (1): 48\u201354. doi:10.1016\/j.anaerobe.2011.09.004. PMID\u00a021945821.^ Yuan, Y; Ohtani, K; Yoshizawa, S; Shimizu, T (Feb 2012). “Complex transcriptional regulation of citrate metabolism in Clostridium perfringens”. Anaerobe. 18 (1): 48\u201354. doi:10.1016\/j.anaerobe.2011.09.004. PMID\u00a021945821.^ Obana, N; Shirahama, Y; Abe, K; Nakamura, K (Sep 2010). “Stabilization of Clostridium perfringens collagenase mRNA by VR-RNA-dependent cleavage in 5\u2032 leader sequence”. Molecular Microbiology. 77 (6): 1416\u20131428. doi:10.1111\/j.1365-2958.2010.07258.x. PMID\u00a020572941.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/vr-rna-wikipedia\/#breadcrumbitem","name":"VR-RNA – Wikipedia"}}]}]