[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/wdr36-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/wdr36-wikipedia\/","headline":"WDR36 – Wikipedia","name":"WDR36 – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens WD repeat-containing protein 36 is a protein that","datePublished":"2015-03-21","dateModified":"2015-03-21","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/wdr36-wikipedia\/","about":["Wiki"],"wordCount":3303,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensWD repeat-containing protein 36 is a protein that in humans is encoded by the WDR36 gene.[5][6][7]This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Mutations in this gene have been associated with adult-onset primary open-angle glaucoma (POAG).[7]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000134987 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000038299 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Bernstein KA, Gallagher JE, Mitchell BM, Granneman S, Baserga SJ (Dec 2004). “The small-subunit processome is a ribosome assembly intermediate”. Eukaryot Cell. 3 (6): 1619\u201326. doi:10.1128\/EC.3.6.1619-1626.2004. PMC\u00a0539036. PMID\u00a015590835.^ Monemi S, Spaeth G, DaSilva A, Popinchalk S, Ilitchev E, Liebmann J, Ritch R, Heon E, Crick RP, Child A, Sarfarazi M (Mar 2005). “Identification of a novel adult-onset primary open-angle glaucoma (POAG) gene on 5q22.1”. Hum Mol Genet. 14 (6): 725\u201333. doi:10.1093\/hmg\/ddi068. PMID\u00a015677485.^ a b “Entrez Gene: WDR36 WD repeat domain 36”.Further reading[edit]Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Mao M, Biery MC, Kobayashi SV,  et\u00a0al. (2005). “T lymphocyte activation gene identification by coregulated expression on DNA microarrays”. Genomics. 83 (6): 989\u201399. doi:10.1016\/j.ygeno.2003.12.019. PMID\u00a015177553.Andersen JS, Lam YW, Leung AK,  et\u00a0al. (2005). “Nucleolar proteome dynamics”. Nature. 433 (7021): 77\u201383. Bibcode:2005Natur.433…77A. doi:10.1038\/nature03207. PMID\u00a015635413. S2CID\u00a04344740.Pang CP, Fan BJ, Canlas O,  et\u00a0al. (2006). “A genome-wide scan maps a novel juvenile-onset primary open angle glaucoma locus to chromosome 5q”. Mol. Vis. 12: 85\u201392. PMID\u00a016518310.Hauser MA, Allingham RR, Linkroum K,  et\u00a0al. (2006). “Distribution of WDR36 DNA sequence variants in patients with primary open-angle glaucoma”. Invest. Ophthalmol. Vis. Sci. 47 (6): 2542\u20136. doi:10.1167\/iovs.05-1476. PMID\u00a016723468.Hewitt AW, Dimasi DP, Mackey DA, Craig JE (2006). “A Glaucoma Case-control Study of the WDR36 Gene D658G sequence variant”. Am. J. Ophthalmol. 142 (2): 324\u20135. doi:10.1016\/j.ajo.2006.02.041. PMID\u00a016876519.Kramer PL, Samples JR, Monemi S,  et\u00a0al. (2006). “The role of the WDR36 gene on chromosome 5q22.1 in a large family with primary open-angle glaucoma mapped to this region”. Arch. Ophthalmol. 124 (9): 1328\u201331. doi:10.1001\/archopht.124.9.1328. PMID\u00a016966629.Weisschuh N, Wolf C, Wissinger B, Gramer E (2007). “Variations in the WDR36 gene in German patients with normal tension glaucoma”. Mol. Vis. 13: 724\u20139. PMC\u00a02765470. PMID\u00a017563723.Miyazawa A, Fuse N, Mengkegale M,  et\u00a0al. (2007). “Association between primary open-angle glaucoma and WDR36 DNA sequence variants in Japanese”. Mol. Vis. 13: 1912\u20139. PMID\u00a017960130.  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