[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/zinc-finger-protein-basonuclin-2-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki24\/zinc-finger-protein-basonuclin-2-wikipedia\/","headline":"Zinc finger protein basonuclin-2 – Wikipedia","name":"Zinc finger protein basonuclin-2 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Zinc finger protein basonuclin-2 is a","datePublished":"2018-10-08","dateModified":"2018-10-08","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki24\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki24\/zinc-finger-protein-basonuclin-2-wikipedia\/","about":["Wiki"],"wordCount":3919,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensZinc finger protein basonuclin-2 is a protein that in humans is encoded by the BNC2 gene.[5][6]BCN2 has recently been shown to influence skin pigmentation levels in Europeans.[7] Genomic region spanning the BCN2 gene has 60% Neanderthal DNA sequence.[8]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4See also[edit]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000173068 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000028487 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Ota T, Suzuki Y, Nishikawa T, Otsuki T, Sugiyama T, Irie R,  et\u00a0al. (Jan 2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nature Genetics. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.^ “Entrez Gene: BNC2 basonuclin 2”.^ Jacobs LC, Wollstein A, Lao O, Hofman A, Klaver CC, Uitterlinden AG, Nijsten T, Kayser M, Liu F (Feb 2013). “Comprehensive candidate gene study highlights UGT1A and BNC2 as new genes determining continuous skin color variation in Europeans”. Human Genetics. 132 (2): 147\u201358. doi:10.1007\/s00439-012-1232-9. PMID\u00a023052946. S2CID\u00a06057298.^ Vattathil S, Akey JM (Oct 2015). “Small Amounts of Archaic Admixture Provide Big Insights into Human History”. Cell. 163 (2): 281\u20134. doi:10.1016\/j.cell.2015.09.042. PMID\u00a026451479.Further reading[edit]Vanhoutteghem A, Djian P (Jan 2007). “The human basonuclin 2 gene has the potential to generate nearly 90,000 mRNA isoforms encoding over 2000 different proteins”. Genomics. 89 (1): 44\u201358. doi:10.1016\/j.ygeno.2006.07.006. PMID\u00a016942855.Vanhoutteghem A, Djian P (Aug 2006). “Basonuclins 1 and 2, whose genes share a common origin, are proteins with widely different properties and functions”. Proceedings of the National Academy of Sciences of the United States of America. 103 (33): 12423\u20138. Bibcode:2006PNAS..10312423V. doi:10.1073\/pnas.0605086103. PMC\u00a01567895. PMID\u00a016891417.Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (Jan 2006). “Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes”. Genome Research. 16 (1): 55\u201365. doi:10.1101\/gr.4039406. PMC\u00a01356129. PMID\u00a016344560.Benevolenskaya EV, Murray HL, Branton P, Young RA, Kaelin WG (Jun 2005). “Binding of pRB to the PHD protein RBP2 promotes cellular differentiation”. Molecular Cell. 18 (6): 623\u201335. doi:10.1016\/j.molcel.2005.05.012. PMID\u00a015949438.Romano RA, Li H, Tummala R, Maul R, Sinha S (May 2004). “Identification of Basonuclin2, a DNA-binding zinc-finger protein expressed in germ tissues and skin keratinocytes”. Genomics. 83 (5): 821\u201333. doi:10.1016\/j.ygeno.2003.11.009. PMID\u00a015081112.Vanhoutteghem A, Djian P (Mar 2004). “Basonuclin 2: an extremely conserved homolog of the zinc finger protein basonuclin”. Proceedings of the National Academy of Sciences of the United States of America. 101 (10): 3468\u201373. Bibcode:2004PNAS..101.3468V. doi:10.1073\/pnas.0400268101. PMC\u00a0373485. PMID\u00a014988505.       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