[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/3%ce%b2-hydroxytibolone-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki41\/3%ce%b2-hydroxytibolone-wikipedia\/","headline":"3\u03b2-Hydroxytibolone – Wikipedia","name":"3\u03b2-Hydroxytibolone – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Chemical compound 3\u03b2-Hydroxytibolone Other names ORG-30126; 7\u03b1-Methyl-17\u03b1-ethynylestr-5(10)-ene-3\u03b2,17\u03b2-diol (3S,7R,8R,9S,13S,14S,17R)-17-ethynyl-7,13-dimethyl-2,3,4,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol CAS Number PubChem CID ChemSpider","datePublished":"2016-11-06","dateModified":"2016-11-06","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki41\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/a\/a8\/3%CE%B2-Hydroxytibolone.svg\/225px-3%CE%B2-Hydroxytibolone.svg.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/a\/a8\/3%CE%B2-Hydroxytibolone.svg\/225px-3%CE%B2-Hydroxytibolone.svg.png","height":"153","width":"225"},"url":"https:\/\/wiki.edu.vn\/en\/wiki41\/3%ce%b2-hydroxytibolone-wikipedia\/","wordCount":1632,"articleBody":" (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Chemical compound3\u03b2-HydroxytiboloneOther namesORG-30126; 7\u03b1-Methyl-17\u03b1-ethynylestr-5(10)-ene-3\u03b2,17\u03b2-diol(3S,7R,8R,9S,13S,14S,17R)-17-ethynyl-7,13-dimethyl-2,3,4,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diolCAS NumberPubChem CIDChemSpiderUNIIFormulaC21H30O2Molar mass314.469\u00a0g\u00b7mol\u221213D model (JSmol)C[C@@H]1CC2=C(CC[C@@H](C2)O)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4InChI=1S\/C21H30O2\/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3\/h1,13,15,17-19,22-23H,5-12H2,2-3H3\/t13-,15+,17-,18+,19-,20+,21+\/m1\/s1Key:YLEUWNOTNJZCBN-XAAPQAIWSA-N3\u03b2-Hydroxytibolone (developmental code name ORG-30126) is a synthetic steroidal estrogen which was never marketed.[1][2] Along with 3\u03b1-hydroxytibolone and \u03b44-tibolone, it is a major active metabolite of tibolone, and 3\u03b1-hydroxytibolone and 3\u03b2-hydroxytibolone are thought to be responsible for the estrogenic activity of tibolone.[1][2]References[edit]ERAgonistsSteroidal: 2-Hydroxyestradiol2-Hydroxyestrone3-Methyl-19-methyleneandrosta-3,5-dien-17\u03b2-ol3\u03b1-Androstanediol3\u03b1,5\u03b1-Dihydrolevonorgestrel3\u03b2,5\u03b1-Dihydrolevonorgestrel3\u03b1-Hydroxytibolone3\u03b2-Hydroxytibolone3\u03b2-Androstanediol4-Androstenediol4-Androstenedione4-Fluoroestradiol4-Hydroxyestradiol4-Hydroxyestrone4-Methoxyestradiol4-Methoxyestrone5-Androstenediol7-Oxo-DHEA7\u03b1-Hydroxy-DHEA7\u03b1-Methylestradiol7\u03b2-Hydroxyepiandrosterone8,9-Dehydroestradiol8,9-Dehydroestrone8\u03b2-VE210\u03b2,17\u03b2-Dihydroxyestra-1,4-dien-3-one (DHED)11\u03b2-Chloromethylestradiol11\u03b2-Methoxyestradiol15\u03b1-Hydroxyestradiol16-Ketoestradiol16-Ketoestrone16\u03b1-Fluoroestradiol16\u03b1-Hydroxy-DHEA16\u03b1-Hydroxyestrone16\u03b1-Iodoestradiol16\u03b1-LE216\u03b2-Hydroxyestrone16\u03b2,17\u03b1-Epiestriol (16\u03b2-hydroxy-17\u03b1-estradiol)17\u03b1-Estradiol (alfatradiol)17\u03b1-Dihydroequilenin17\u03b1-Dihydroequilin17\u03b1-Epiestriol (16\u03b1-hydroxy-17\u03b1-estradiol)17\u03b1-Ethynyl-3\u03b1-androstanediol17\u03b1-Ethynyl-3\u03b2-androstanediol17\u03b2-Dihydroequilenin17\u03b2-Dihydroequilin17\u03b2-Methyl-17\u03b1-dihydroequileninAbirateroneAbiraterone acetateAlestramustineAlmestroneAnabolic steroids (e.g., testosterone and esters, methyltestosterone, metandienone (methandrostenolone), nandrolone and esters, many others; via estrogenic metabolites)AtrimustineBolandiolBolandiol dipropionateButolameClomestroneCloxestradiolConjugated estriolConjugated estrogensCyclodiolCyclotriolDHEADHEA-Sent-EstradiolEpiestriol (16\u03b2-epiestriol, 16\u03b2-hydroxy-17\u03b2-estradiol)EpimestrolEquileninEquilinERA-63 (ORG-37663)Esterified estrogensEstetrolEstradiolEstramustineEstramustine phosphateEstrapronicateEstrazinolEstriolEstrofurateEstrogenic substancesEstromustineEstroneEtamestrol (eptamestrol)EthinylandrostenediolEthinylestradiolEthinylestriolEthylestradiolEtynodiolEtynodiol diacetateHexolameHippulinHydroxyestrone diacetateLynestrenolLynestrenol phenylpropionateMestranolMethylestradiolMoxestrolMytatrienediolNilestriolNorethisteroneNoretynodrelOrestratePentolameProdiameProlamePromestrieneRU-16117QuinestradolQuinestrolTiboloneXenoestrogens: Anise-related (e.g., anethole, anol, dianethole, dianol, photoanethole)Chalconoids (e.g., isoliquiritigenin, phloretin, phlorizin (phloridzin), wedelolactone)Coumestans (e.g., coumestrol, psoralidin)Flavonoids (incl. 7,8-DHF, 8-prenylnaringenin, apigenin, baicalein, baicalin, biochanin A, calycosin, catechin, daidzein, daidzin, ECG, EGCG, epicatechin, equol, formononetin, glabrene, glabridin, genistein, genistin, glycitein, kaempferol, liquiritigenin, mirificin, myricetin, naringenin, penduletin, pinocembrin, prunetin, puerarin, quercetin, tectoridin, tectorigenin)Lavender oilLignans (e.g., enterodiol, enterolactone, nyasol (cis-hinokiresinol))Metalloestrogens (e.g., cadmium)Pesticides (e.g., alternariol, dieldrin, endosulfan, fenarimol, HPTE, methiocarb, methoxychlor, triclocarban, triclosan)Phytosteroids (e.g., digitoxin (digitalis), diosgenin, guggulsterone)Phytosterols (e.g., \u03b2-sitosterol, campesterol, stigmasterol)Resorcylic acid lactones (e.g., zearalanone, \u03b1-zearalenol, \u03b2-zearalenol, zearalenone, zeranol (\u03b1-zearalanol), taleranol (teranol, \u03b2-zearalanol))Steroid-like (e.g., deoxymiroestrol, miroestrol)Stilbenoids (e.g., resveratrol, rhaponticin)Synthetic xenoestrogens (e.g., alkylphenols, bisphenols (e.g., BPA, BPF, BPS), DDT, parabens, PBBs, PHBA, phthalates, PCBs)Others (e.g., agnuside, rotundifuran)Mixed(SERMs)AntagonistsCoregulator-binding modulators: ERX-11GPER (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4 (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/3%ce%b2-hydroxytibolone-wikipedia\/#breadcrumbitem","name":"3\u03b2-Hydroxytibolone – Wikipedia"}}]}]