[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/ashwani-kumar-scientist-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki41\/ashwani-kumar-scientist-wikipedia\/","headline":"Ashwani Kumar (scientist) – Wikipedia","name":"Ashwani Kumar (scientist) – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Indian biologist This article is about the scientist. 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For other people with a similar name, see Ashwani Kumar.Ashwani Kumar is an Indian bacteriologist and the Senior Principal Scientist at the Institute of Microbial Technology (ImTech). He is known for his studies on Mycobacterium tuberculosis, the causative agent of tuberculosis. His laboratory focuses on understanding the reasons for drug tolerance observed in humans. His laboratory hypothesizes that tuberculosis is a biofilm infection, so its treatment needs the administration of multiple drugs for at least six months. The Department of Science and Technology has awarded him Swarnajayanti Fellowship for 2016\u20132017. Department of Biotechnology has awarded him the National Bioscience Prize (2017-18). He was also selected for DBT\/Wellcome Trust India Alliance Senior Fellowship (2021 to 2026). He was elected as a Fellow of the National Academy of Sciences, India, in 2022.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Table of ContentsBiography[edit]Selected bibliography[edit]Articles[edit]See also[edit]References[edit]External links[edit]Biography[edit]Ashwani Kumar is a Senior Principal Scientist at the Institute of Microbial Technology (ImTech)[1] where he heads a laboratory, popularly known as Ashwani Kumar’s Lab.[2] and serves as a principal investigator.[3] He is known to have done extensive research on Mycobacterium tuberculosis and has served as a member of MDRIpred project,[4] an open source server for predicting inhibitors against drug-tolerant M.tb H37Rv.[5] He has published a number of articles;[6]ResearchGate, an online repository of scientific articles has listed 31 of them.[7] His laboratory has demonstrated the presence of cellulose encased biofilms[8] inside the hosts including human.[9] He also works on regulation of autophagy by signalling gases such as carbon monoxide[10] and hydrogen sulfide.[11] The Department of Biotechnology of the Government of India awarded him the National Bioscience Award for Career Development, one of the highest Indian science awards, for him contributions to biosciences, in 2017\u201318.[12]Selected bibliography[edit]Articles[edit]Chakraborty, Poushali; Bajeli, Sapna; Kaushal, Deepak; Radotra, Bishan Dass; Kumar, Ashwani (11 March 2021). “Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis”. Nature Communications. 12 (1): 1606. doi:10.1038\/s41467-021-21748-6. PMC\u00a07952908. PMID\u00a033707445.Iqbal, Iram Khan; Bajeli, Sapna; Sahu, Shivani; Bhat, Shabir Ahmad; Kumar, Ashwani (18 January 2021). “Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy”. Autophagy. 17 (11): 3511\u20133529. doi:10.1080\/15548627.2021.1876342. PMC\u00a08632308. PMID\u00a033459133. S2CID\u00a0231636126.Kumar, Ashwani (2016-06-23). “House of cellulose \u2013 a new hideout for drug tolerant Mycobacterium tuberculosis”. Microbial Cell. 3 (7): 299\u2013301. doi:10.15698\/mic2016.07.515. ISSN\u00a02311-2638. PMC\u00a05354596. PMID\u00a028357368.Kumar, Ashwani; Bhatt, Deepak; Mavi, Parminder Singh; Trivedi, Abhishek (2016-04-25). “Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis”. Nature Communications. 7: 11392. Bibcode:2016NatCo…711392T. doi:10.1038\/ncomms11392. ISSN\u00a02041-1723. PMC\u00a04848537. PMID\u00a027109928.Nisha Singh, Pallavi Kansal, Zeeshan Ahmad, Navin Baid, Hariom Kushwaha, Neeraj Khatri, Ashwani Kumar. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3\/calcineurin-TFEB (transcription factor EB) axis. Autophagy. 2018. doi: 10.1080\/15548627.2018.1436936.Singh, Nisha; Vats, Asheema; Sharma, Aditi; Arora, Amit; Kumar, Ashwani (2017-06-21). “The development of lower respiratory tract microbiome in mice”. Microbiome. 5 (1): 61. doi:10.1186\/s40168-017-0277-3. ISSN\u00a02049-2618. PMC\u00a05479047. PMID\u00a028637485.Nupur, L. N. U.; Vats, Asheema; Dhanda, Sandeep Kumar; Raghava, Gajendra P. S.; Pinnaka, Anil Kumar; Kumar, Ashwani (2016-05-26). “ProCarDB: a database of bacterial carotenoids”. BMC Microbiology. 16 (1): 96. doi:10.1186\/s12866-016-0715-6. ISSN\u00a01471-2180. PMC\u00a04882832. PMID\u00a027230105.Sarkar, Dibyendu; Kumar, Ashwani; Sevalkar, Ritesh Rajesh; Singh, Nisha; Bansal, Roohi; Goyal, Rajni; Kumar, Vijjamarri Anil (2016-09-02). “EspR-dependent ESAT-6 Protein Secretion of Mycobacterium tuberculosis Requires the Presence of Virulence Regulator PhoP”. Journal of Biological Chemistry. 291 (36): 19018\u201319030. doi:10.1074\/jbc.M116.746289. ISSN\u00a01083-351X. PMC\u00a05009273. PMID\u00a027445330.See also[edit]References[edit]^ “Ashwani Kumar – ImTech profile”. Institute of Microbial Technology. 2019-01-14. Retrieved 2019-01-14.^ “Ashwani Kumar’s lab – Institute of Microbial Technology (IMTECH)”. ResearchGate. 2019-01-14. Retrieved 2019-01-14.^ “Addgene: Ashwani Kumar Lab Plasmids”. www.addgene.org. 2019-01-14. Retrieved 2019-01-14.^ “MDRIpred: A webserver for predicting inhibitors against drug resistant M.Tuberculosis”. crdd.osdd.net. 2019-01-14. Retrieved 2019-01-14.^ “Welcome to MDRIpred”. crdd.osdd.net. 2019-01-14. Retrieved 2019-01-14.^ “Ashwani Kumar – Google Scholar Citations”. scholar.google.com. 2019-01-14. Retrieved 2019-01-14.^ “Ashwani Kumar Institute of Microbial Technology – IMTECH \u00b7 Molecular Mycobacteriology 28 36 \u00b7”. ResearchGate. 2019-01-14. Retrieved 2019-01-14.^ Trivedi, Abhishek; Mavi, Parminder Singh; Bhatt, Deepak; Kumar, Ashwani (September 2016). “Thiol reductive stress induces cellulose-anchored biofilm formation in Mycobacterium tuberculosis”. Nature Communications. 7 (1): 11392. Bibcode:2016NatCo…711392T. doi:10.1038\/ncomms11392. ISSN\u00a02041-1723. PMC\u00a04848537. PMID\u00a027109928.^ Chakraborty, Poushali; Bajeli, Sapna; Kaushal, Deepak; Radotra, Bishan Dass; Kumar, Ashwani (2021-03-11). “Biofilm formation in the lung contributes to virulence and drug tolerance of Mycobacterium tuberculosis”. Nature Communications. 12 (1): 1606. doi:10.1038\/s41467-021-21748-6. ISSN\u00a02041-1723. PMC\u00a07952908. PMID\u00a033707445.^ Singh, Nisha; Kansal, Pallavi; Ahmad, Zeeshan; Baid, Navin; Kushwaha, Hariom; Khatri, Neeraj; Kumar, Ashwani (2018-06-03). “Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy depends on HMOX1 (heme oxygenase 1)-mediated increase in intracellular calcium levels and modulation of PPP3\/calcineurin-TFEB (transcription factor EB) axis”. Autophagy. 14 (6): 972\u2013991. doi:10.1080\/15548627.2018.1436936. ISSN\u00a01554-8627. PMC\u00a06103408. PMID\u00a029457983.^ Iqbal, Iram Khan; Bajeli, Sapna; Sahu, Shivani; Bhat, Shabir Ahmad; Kumar, Ashwani (2021-01-18). “Hydrogen sulfide-induced GAPDH sulfhydration disrupts the CCAR2-SIRT1 interaction to initiate autophagy”. Autophagy. 17 (11): 3511\u20133529. doi:10.1080\/15548627.2021.1876342. ISSN\u00a01554-8627. PMC\u00a08632308. PMID\u00a033459133. S2CID\u00a0231636126.^ “Awardees of National Bioscience Awards for Career Development” (PDF). Department of Biotechnology. 2019. Retrieved 2017-11-20.External links[edit]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4     (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/ashwani-kumar-scientist-wikipedia\/#breadcrumbitem","name":"Ashwani Kumar (scientist) – Wikipedia"}}]}]