[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/brinp3-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki41\/brinp3-wikipedia\/","headline":"BRINP3 – Wikipedia","name":"BRINP3 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens BMP\/retinoic acid inducible neural specific 3","datePublished":"2016-12-06","dateModified":"2016-12-06","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki41\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki41\/brinp3-wikipedia\/","wordCount":2972,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensBMP\/retinoic acid inducible neural specific 3 is a protein that in humans is encoded by the BRINP3 gene.[5]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Function[edit]This gene is overexpressed in pituitary tumors but is underexpressed in tongue squamous cell carcinomas, ulcerative colitis, and peri-implantitis. Polymorphisms that increase expression of this gene have been shown to increase vascular inflammation, and an association of this gene with myocardial infarction has been demonstrated. Finally, hypermethylation of this gene may find usefulness as a biomarker for gastric cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015].References[edit]Further reading[edit]Shorts-Cary L, Xu M, Ertel J, Kleinschmidt-Demasters BK, Lillehei K, Matsuoka I, Nielsen-Preiss S, Wierman ME (March 2007). “Bone morphogenetic protein and retinoic acid-inducible neural specific protein-3 is expressed in gonadotrope cell pituitary adenomas and induces proliferation, migration, and invasion”. Endocrinology. 148 (3): 967\u201375. doi:10.1210\/en.2006-0905. PMID\u00a017138656.Vasan RS, Larson MG, Aragam J, Wang TJ, Mitchell GF, Kathiresan S, Newton-Cheh C, Vita JA, Keyes MJ, O’Donnell CJ, Levy D, Benjamin EJ (September 2007). “Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study”. BMC Med. Genet. 8 Suppl 1: S2. doi:10.1186\/1471-2350-8-S1-S2. PMC\u00a01995617. PMID\u00a017903301.Connelly JJ, Shah SH, Doss JF, Gadson S, Nelson S, Crosslin DR, Hale AB, Lou X, Wang T, Haynes C, Seo D, Crossman DC, Mooser V, Granger CB, Jones CJ, Kraus WE, Hauser ER, Gregory SG (April 2008). “Genetic and functional association of FAM5C with myocardial infarction”. BMC Med. Genet. 9: 33. doi:10.1186\/1471-2350-9-33. PMC\u00a02383879. PMID\u00a018430236.Connelly JJ, Shah SH, Doss JF, Gadson S, Nelson S, Crosslin DR, Hale AB, Lou X, Wang T, Haynes C, Seo D, Crossman DC, Mooser V, Granger CB, Jones CJ, Kraus WE, Hauser ER, Gregory SG (April 2008). “Genetic and functional association of FAM5C with myocardial infarction”. BMC Med. Genet. 9: 33. doi:10.1186\/1471-2350-9-33. PMC\u00a02383879. PMID\u00a018430236.Kuroiwa T, Yamamoto N, Onda T, Shibahara T (November 2009). “Expression of the FAM5C in tongue squamous cell carcinoma”. Oncol. Rep. 22 (5): 1005\u201311. doi:10.3892\/or_00000528. PMID\u00a019787213.Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). “Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score”. Mol. Med. 16 (7\u20138): 247\u201353. doi:10.2119\/molmed.2009.00159. PMC\u00a02896464. PMID\u00a020379614.Carvalho FM, Tinoco EM, Deeley K, Duarte PM, Faveri M, Marques MR, Mendon\u00e7a AC, Wang X, Cuenco K, Menezes R, Garlet GP, Vieira AR (April 2010). “FAM5C contributes to aggressive periodontitis”. PLOS ONE. 5 (4): e10053. Bibcode:2010PLoSO…510053C. doi:10.1371\/journal.pone.0010053. PMC\u00a02850931. PMID\u00a020383335.Carvalho FM, Tinoco EM, Deeley K, Duarte PM, Faveri M, Marques MR, Mendon\u00e7a AC, Wang X, Cuenco K, Menezes R, Garlet GP, Vieira AR (April 2010). “FAM5C contributes to aggressive periodontitis”. PLOS ONE. 5 (4): e10053. Bibcode:2010PLoSO…510053C. doi:10.1371\/journal.pone.0010053. PMC\u00a02850931. PMID\u00a020383335.Cline JL, Beckie TM (April 2013). “The relationships between FAM5C SNP (rs10920501) variability and metabolic syndrome and inflammation in women with coronary heart disease”. Biol Res Nurs. 15 (2): 160\u20136. doi:10.1177\/1099800411424487. PMC\u00a04108984. PMID\u00a022013132.This article incorporates text from the United States National Library of Medicine, which is in the public domain.     (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki41\/brinp3-wikipedia\/#breadcrumbitem","name":"BRINP3 – Wikipedia"}}]}]