[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki5\/mitochondrial-ribosomal-protein-l39-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki5\/mitochondrial-ribosomal-protein-l39-wikipedia\/","headline":"Mitochondrial ribosomal protein L39 – Wikipedia","name":"Mitochondrial ribosomal protein L39 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens MRPL39 Identifiers Aliases MRPL39, C21orf92, L39mt,","datePublished":"2018-08-11","dateModified":"2018-08-11","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki5\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki5\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki5\/mitochondrial-ribosomal-protein-l39-wikipedia\/","wordCount":3185,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensMRPL39IdentifiersAliasesMRPL39, C21orf92, L39mt, MRP-L5, MRPL5, PRED22, PRED66, RPML5, MSTP003, mitochondrial ribosomal protein L39, L5mtExternal IDsOMIM: 611845 MGI: 1351620 HomoloGene: 9679 GeneCards: MRPL39 Wikidata39S ribosomal protein L39, mitochondrial is a protein that in humans is encoded by the MRPL39 gene.[5][6]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to this gene is found on chromosome 5q.[6]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000154719 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022889 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Kenmochi N, Suzuki T, Uechi T, Magoori M, Kuniba M, Higa S, Watanabe K, Tanaka T (Sep 2001). “The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders”. Genomics. 77 (1\u20132): 65\u201370. doi:10.1006\/geno.2001.6622. PMID\u00a011543634.^ a b “Entrez Gene: MRPL39 mitochondrial ribosomal protein L39”.Further reading[edit]Maruyama K, Sugano S (1994). “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1\u20132): 171\u20134. doi:10.1016\/0378-1119(94)90802-8. PMID\u00a08125298.Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K,  et\u00a0al. (1997). “Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library”. Gene. 200 (1\u20132): 149\u201356. doi:10.1016\/S0378-1119(97)00411-3. PMID\u00a09373149.O’Brien TW, Fiesler SE, Denslow ND,  et\u00a0al. (2000). “Mammalian mitochondrial ribosomal proteins (2). Amino acid sequencing, characterization, and identification of corresponding gene sequences”. J. Biol. Chem. 274 (51): 36043\u201351. doi:10.1074\/jbc.274.51.36043. PMID\u00a010593885.Spirina O, Bykhovskaya Y, Kajava AV,  et\u00a0al. (2001). “Heart-specific splice-variant of a human mitochondrial ribosomal protein (mRNA processing; tissue specific splicing)”. Gene. 261 (2): 229\u201334. doi:10.1016\/S0378-1119(00)00504-7. PMID\u00a011167009.O’Brien TW (2002). “Evolution of a protein-rich mitochondrial ribosome: implications for human genetic disease”. Gene. 286 (1): 73\u20139. doi:10.1016\/S0378-1119(01)00808-3. PMID\u00a011943462.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Zhang Z, Gerstein M (2003). “Identification and characterization of over 100 mitochondrial ribosomal protein pseudogenes in the human genome”. Genomics. 81 (5): 468\u201380. doi:10.1016\/S0888-7543(03)00004-1. PMID\u00a012706105.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.     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