[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki7\/tuba8-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki7\/tuba8-wikipedia\/","headline":"TUBA8 – Wikipedia","name":"TUBA8 – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens Tubulin alpha-8 chain is a protein that in","datePublished":"2018-03-28","dateModified":"2018-03-28","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki7\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki7\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/11\/book.png","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/11\/book.png","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/3\/3b\/PDB_1tub_EBI.jpg\/180px-PDB_1tub_EBI.jpg","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/3\/3b\/PDB_1tub_EBI.jpg\/180px-PDB_1tub_EBI.jpg","height":"135","width":"180"},"url":"https:\/\/wiki.edu.vn\/en\/wiki7\/tuba8-wikipedia\/","wordCount":5765,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensTubulin alpha-8 chain is a protein that in humans is encoded by the TUBA8 gene.[5][6][7][8]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000183785 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030137 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Stanchi F, Corso V, Scannapieco P, Ievolella C, Negrisolo E, Tiso N, Lanfranchi G, Valle G (May 2000). “TUBA8: A new tissue-specific isoform of alpha-tubulin that is highly conserved in human and mouse”. Biochem Biophys Res Commun. 270 (3): 1111\u20138. doi:10.1006\/bbrc.2000.2571. PMID\u00a010772959.^ Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O’Brien KP,  et\u00a0al. (Dec 1999). “The DNA sequence of human chromosome 22”. Nature. 402 (6761): 489\u201395. Bibcode:1999Natur.402..489D. doi:10.1038\/990031. PMID\u00a010591208.^ “Entrez Gene: TUBA8 tubulin, alpha 8”.^ “GeneCards: TUBA8 gene”.Further reading[edit]Alexandrova N, Niklinski J, Bliskovsky V,  et\u00a0al. (1995). “The N-terminal domain of c-Myc associates with alpha-tubulin and microtubules in vivo and in vitro”. Mol. Cell. Biol. 15 (9): 5188\u201395. doi:10.1128\/MCB.15.9.5188. PMC\u00a0230766. PMID\u00a07651436.Feierbach B, Nogales E, Downing KH, Stearns T (1999). “Alf1p, a CLIP-170 domain-containing protein, is functionally and physically associated with alpha-tubulin”. J. Cell Biol. 144 (1): 113\u201324. doi:10.1083\/jcb.144.1.113. PMC\u00a02148126. PMID\u00a09885248.Herreros L, Rodr\u00edguez-Fernandez JL, Brown MC,  et\u00a0al. (2000). “Paxillin localizes to the lymphocyte microtubule organizing center and associates with the microtubule cytoskeleton”. J. Biol. Chem. 275 (34): 26436\u201340. doi:10.1074\/jbc.M003970200. PMID\u00a010840040.Watts NR, Sackett DL, Ward RD,  et\u00a0al. (2000). “HIV-1 rev depolymerizes microtubules to form stable bilayered rings”. J. Cell Biol. 150 (2): 349\u201360. doi:10.1083\/jcb.150.2.349. PMC\u00a02180222. PMID\u00a010908577.Germani A, Bruzzoni-Giovanelli H, Fellous A,  et\u00a0al. (2001). “SIAH-1 interacts with alpha-tubulin and degrades the kinesin Kid by the proteasome pathway during mitosis”. Oncogene. 19 (52): 5997\u20136006. doi:10.1038\/sj.onc.1204002. PMID\u00a011146551.Saugstad JA, Yang S, Pohl J,  et\u00a0al. (2002). “Interaction between metabotropic glutamate receptor 7 and alpha tubulin”. J. Neurochem. 80 (6): 980\u20138. doi:10.1046\/j.0022-3042.2002.00778.x. PMC\u00a02925652. PMID\u00a011953448.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Chen D, Wang M, Zhou S, Zhou Q (2004). “HIV-1 Tat targets microtubules to induce apoptosis, a process promoted by the pro-apoptotic Bcl-2 relative Bim”. EMBO J. 21 (24): 6801\u201310. doi:10.1093\/emboj\/cdf683. PMC\u00a0139103. PMID\u00a012486001.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Xu Y, Kulkosky J, Acheampong E,  et\u00a0al. (2004). “HIV-1-mediated apoptosis of neuronal cells: Proximal molecular mechanisms of HIV-1-induced encephalopathy”. Proc. Natl. Acad. Sci. U.S.A. 101 (18): 7070\u20135. doi:10.1073\/pnas.0304859101. PMC\u00a0406467. PMID\u00a015103018.Campbell GR, Pasquier E, Watkins J,  et\u00a0al. (2005). “The glutamine-rich region of the HIV-1 Tat protein is involved in T-cell apoptosis”. J. Biol. Chem. 279 (46): 48197\u2013204. doi:10.1074\/jbc.M406195200. PMID\u00a015331610.Collins JE, Wright CL, Edwards CA,  et\u00a0al. (2005). “A genome annotation-driven approach to cloning the human ORFeome”. Genome Biol. 5 (10): R84. doi:10.1186\/gb-2004-5-10-r84. PMC\u00a0545604. PMID\u00a015461802.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.de Mareuil J, Carre M, Barbier P,  et\u00a0al. (2006). “HIV-1 Tat protein enhances microtubule polymerization”. Retrovirology. 2: 5. doi:10.1186\/1742-4690-2-5. PMC\u00a0549075. PMID\u00a015691386.Giacca M (2006). “HIV-1 Tat, apoptosis and the mitochondria: a tubulin link?”. Retrovirology. 2: 7. doi:10.1186\/1742-4690-2-7. PMC\u00a0549042. PMID\u00a015698476.Valenzuela-Fern\u00e1ndez A, Alvarez S, Gordon-Alonso M,  et\u00a0al. (2006). “Histone deacetylase 6 regulates human immunodeficiency virus type 1 infection”. Mol. Biol. Cell. 16 (11): 5445\u201354. doi:10.1091\/mbc.E05-04-0354. PMC\u00a01266439. PMID\u00a016148047.Canani RB, De Marco G, Passariello A,  et\u00a0al. (2006). “Inhibitory effect of HIV-1 Tat protein on the sodium-D-glucose symporter of human intestinal epithelial cells”. AIDS. 20 (1): 5\u201310. doi:10.1097\/01.aids.0000198088.85572.68. PMID\u00a016327313. S2CID\u00a021499158.PDB gallery1tub: TUBULIN ALPHA-BETA DIMER, ELECTRON DIFFRACTION1tvk: The binding mode of epothilone A on a,b-tubulin by electron crystallography1z2b: Tubulin-colchicine-vinblastine: stathmin-like domain complex"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki7\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki7\/tuba8-wikipedia\/#breadcrumbitem","name":"TUBA8 – Wikipedia"}}]}]