[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki7\/wac-gene-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki7\/wac-gene-wikipedia\/","headline":"WAC (gene) – Wikipedia","name":"WAC (gene) – Wikipedia","description":"From Wikipedia, the free encyclopedia Protein-coding gene in the species Homo sapiens WW domain-containing adapter protein with coiled-coil is a","datePublished":"2020-10-26","dateModified":"2020-10-26","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki7\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki7\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/cd810e53c1408c38cc766bc14e7ce26a?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/cd810e53c1408c38cc766bc14e7ce26a?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/11\/book.png","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/11\/book.png","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki7\/wac-gene-wikipedia\/","wordCount":3127,"articleBody":"From Wikipedia, the free encyclopediaProtein-coding gene in the species Homo sapiensWW domain-containing adapter protein with coiled-coil is a protein that in humans is encoded by the WAC gene.[5][6]The protein encoded by this gene contains a WW domain, which is a protein module found in a wide range of signaling proteins. This domain mediates protein-protein interactions and binds proteins containing short linear peptide motifs that are proline-rich or contain at least one proline. This gene product shares 94% sequence identity with the WAC protein in mouse, however, its exact function is not known.[6]References[edit]Further reading[edit]Sudol M, Sliwa K, Russo T (2001). “Functions of WW domains in the nucleus”. FEBS Lett. 490 (3): 190\u20135. doi:10.1016\/S0014-5793(01)02122-6. PMID\u00a011223034. S2CID\u00a020463526.Maruyama K, Sugano S (1994). “Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides”. Gene. 138 (1\u20132): 171\u20134. doi:10.1016\/0378-1119(94)90802-8. PMID\u00a08125298.Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K,  et\u00a0al. (1997). “Construction and characterization of a full length-enriched and a 5′-end-enriched cDNA library”. Gene. 200 (1\u20132): 149\u201356. doi:10.1016\/S0378-1119(97)00411-3. PMID\u00a09373149.Zhang QH, Ye M, Wu XY,  et\u00a0al. (2001). “Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem\/progenitor cells”. Genome Res. 10 (10): 1546\u201360. doi:10.1101\/gr.140200. PMC\u00a0310934. PMID\u00a011042152.Nagase T, Nakayama M, Nakajima D,  et\u00a0al. (2001). “Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro”. DNA Res. 8 (2): 85\u201395. doi:10.1093\/dnares\/8.2.85. PMID\u00a011347906.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2003). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Deloukas P, Earthrowl ME, Grafham DV,  et\u00a0al. (2004). “The DNA sequence and comparative analysis of human chromosome 10”. Nature. 429 (6990): 375\u201381. Bibcode:2004Natur.429..375D. doi:10.1038\/nature02462. PMID\u00a015164054.Gerhard DS, Wagner L, Feingold EA,  et\u00a0al. (2004). “The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)”. Genome Res. 14 (10B): 2121\u20137. doi:10.1101\/gr.2596504. PMC\u00a0528928. PMID\u00a015489334.Rual JF, Venkatesan K, Hao T,  et\u00a0al. (2005). “Towards a proteome-scale map of the human protein-protein interaction network”. Nature. 437 (7062): 1173\u20138. Bibcode:2005Natur.437.1173R. doi:10.1038\/nature04209. PMID\u00a016189514. S2CID\u00a04427026.Lim J, Hao T, Shaw C,  et\u00a0al. (2006). “A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration”. Cell. 125 (4): 801\u201314. doi:10.1016\/j.cell.2006.03.032. PMID\u00a016713569. S2CID\u00a013709685.Beausoleil SA, Vill\u00e9n J, Gerber SA,  et\u00a0al. (2006). “A probability-based approach for high-throughput protein phosphorylation analysis and site localization”. Nat. Biotechnol. 24 (10): 1285\u201392. doi:10.1038\/nbt1240. PMID\u00a016964243. S2CID\u00a014294292.Olsen JV, Blagoev B, Gnad F,  et\u00a0al. (2006). “Global, in vivo, and site-specific phosphorylation dynamics in signaling networks”. Cell. 127 (3): 635\u201348. doi:10.1016\/j.cell.2006.09.026. PMID\u00a017081983. 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