[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/en\/wiki8\/gnpda2-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/en\/wiki8\/gnpda2-wikipedia\/","headline":"GNPDA2 – Wikipedia","name":"GNPDA2 – Wikipedia","description":"before-content-x4 From Wikipedia, the free encyclopedia after-content-x4 Protein-coding gene in the species Homo sapiens Glucosamine-6-phosphate deaminase 2 also known as","datePublished":"2019-06-09","dateModified":"2019-06-09","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/en\/wiki8\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/en\/wiki8\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","url":"https:\/\/en.wikipedia.org\/wiki\/Special:CentralAutoLogin\/start?type=1x1","height":"1","width":"1"},"url":"https:\/\/wiki.edu.vn\/en\/wiki8\/gnpda2-wikipedia\/","wordCount":3971,"articleBody":"     (adsbygoogle = window.adsbygoogle || []).push({});before-content-x4From Wikipedia, the free encyclopedia       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Protein-coding gene in the species Homo sapiensGlucosamine-6-phosphate deaminase 2 also known as GNPDA2 is an enzyme that in humans is encoded by the GNPDA2 gene.[5]       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4Clinical significance[edit]Variants of the GNPDA2 gene may be associated with obesity.[6][7][8]References[edit]^ a b c GRCh38: Ensembl release 89: ENSG00000163281 – Ensembl, May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029209 – Ensembl, May 2017^ “Human PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ “Mouse PubMed Reference:”. National Center for Biotechnology Information, U.S. National Library of Medicine.^ Arreola R, Valderrama B, Morante ML, Horjales E (September 2003). “Two mammalian glucosamine-6-phosphate deaminases: a structural and genetic study”. FEBS Lett. 551 (1\u20133): 63\u201370. doi:10.1016\/S0014-5793(03)00896-2. PMID\u00a012965206. S2CID\u00a045050024.^ Zhao J, Bradfield JP, Li M,  et\u00a0al. (May 2009). “The role of obesity-associated loci identified in genome wide association studies in the determination of pediatric BMI”. Obesity (Silver Spring). 17 (12): 2254\u20137. doi:10.1038\/oby.2009.159. PMC\u00a02860782. PMID\u00a019478790.^ Renstr\u00f6m F, Payne F, Nordstr\u00f6m A, Brito EC, Rolandsson O, Hallmans G, Barroso I, Nordstr\u00f6m P, Franks PW (April 2009). “Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden”. Hum. Mol. Genet. 18 (8): 1489\u201396. doi:10.1093\/hmg\/ddp041. PMC\u00a02664142. PMID\u00a019164386.^ Willer CJ, Speliotes EK, Loos RJ,  et\u00a0al. (January 2009). “Six new loci associated with body mass index highlight a neuronal influence on body weight regulation”. Nat. Genet. 41 (1): 25\u201334. doi:10.1038\/ng.287. PMC\u00a02695662. PMID\u00a019079261.Further reading[edit]Bauer F, Elbers CC, Adan RA,  et\u00a0al. (2009). “Obesity genes identified in genome-wide association studies are associated with adiposity measures and potentially with nutrient-specific food preference”. Am. J. Clin. Nutr. 90 (4): 951\u20139. doi:10.3945\/ajcn.2009.27781. PMID\u00a019692490.Ota T, Suzuki Y, Nishikawa T,  et\u00a0al. (2004). “Complete sequencing and characterization of 21,243 full-length human cDNAs”. Nat. Genet. 36 (1): 40\u20135. doi:10.1038\/ng1285. PMID\u00a014702039.Haupt A, Thamer C, Heni M,  et\u00a0al. (2009). “Novel Obesity Risk Loci Do Not Determine Distribution of Body Fat Depots: A Whole-body MRI\/MRS study”. Obesity (Silver Spring). 18 (6): 1212\u20137. doi:10.1038\/oby.2009.413. PMID\u00a019910938. S2CID\u00a09601431.Li S, Zhao JH, Luan J,  et\u00a0al. (2010). “Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies”. Am. J. Clin. Nutr. 91 (1): 184\u201390. doi:10.3945\/ajcn.2009.28403. PMID\u00a019812171.Strausberg RL, Feingold EA, Grouse LH,  et\u00a0al. (2002). “Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences”. Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899\u2013903. Bibcode:2002PNAS…9916899M. doi:10.1073\/pnas.242603899. PMC\u00a0139241. PMID\u00a012477932.Brandys MK, van Elburg AA, Loos RJ,  et\u00a0al. (2010). “Are recently identified genetic variants regulating BMI in the general population associated with anorexia nervosa?”. Am. J. Med. Genet. B Neuropsychiatr. Genet. 153B (2): 695\u20139. doi:10.1002\/ajmg.b.31026. PMID\u00a019746409. S2CID\u00a045793585.Renstr\u00f6m F, Payne F, Nordstr\u00f6m A,  et\u00a0al. (2009). “Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden”. Hum. Mol. Genet. 18 (8): 1489\u201396. doi:10.1093\/hmg\/ddp041. PMC\u00a02664142. PMID\u00a019164386.He M, Cornelis MC, Franks PW,  et\u00a0al. (2010). “Obesity Genotype Score and Cardiovascular Risk in Women with Type 2 Diabetes”. Arterioscler. Thromb. Vasc. Biol. 30 (2): 327\u201332. doi:10.1161\/ATVBAHA.109.196196. PMC\u00a03061473. PMID\u00a019910641.Barbe L, Lundberg E, Oksvold P,  et\u00a0al. (2008). “Toward a confocal subcellular atlas of the human proteome”. Mol. Cell. Proteomics. 7 (3): 499\u2013508. doi:10.1074\/mcp.M700325-MCP200. PMID\u00a018029348.Hotta K, Nakamura M, Nakamura T,  et\u00a0al. (2009). “Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population”. J. Hum. Genet. 54 (12): 727\u201331. doi:10.1038\/jhg.2009.106. PMID\u00a019851340.       (adsbygoogle = window.adsbygoogle || []).push({});after-content-x4"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki8\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/en\/wiki8\/gnpda2-wikipedia\/#breadcrumbitem","name":"GNPDA2 – Wikipedia"}}]}]