[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/jp\/wiki\/2020\/03\/26\/%e5%85%8d%e7%96%ab%e3%82%b0%e3%83%ad%e3%83%96%e3%83%aa%e3%83%b3%e8%bb%bd%e9%8e%96-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/jp\/wiki\/2020\/03\/26\/%e5%85%8d%e7%96%ab%e3%82%b0%e3%83%ad%e3%83%96%e3%83%aa%e3%83%b3%e8%bb%bd%e9%8e%96-wikipedia\/","headline":"\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8efd\u9396 – Wikipedia","name":"\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8efd\u9396 – Wikipedia","description":"\u5178\u578b\u7684\u306a\u6297\u4f53\u306e\u6a21\u5f0f\u56f3\u30022\u3064\u306eIg\u91cd\u9396\uff08\u9752\uff09\u3068\u8efd\u9396\uff08\u7dd1\uff09\u304c\u30b8\u30b9\u30eb\u30d5\u30a3\u30c9\u7d50\u5408\u306b\u3088\u3063\u3066\u9023\u7d50\u3055\u308c\u3066\u3044\u308b\u3002\u5b9a\u5e38\u9818\u57df\uff08C\uff09\u3068\u53ef\u5909\u9818\u57df\uff08V\uff09\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002 \u6297\u4f53\u5206\u5b50\u306e\u30ea\u30dc\u30f3\u56f3\u30022\u3064\u306e\u91cd\u9396\u306f\u8d64\u3068\u9752\u3067\u30012\u3064\u306e\u8efd\u9396\u306f\u7dd1\u3068\u9ec4\u3067\u793a\u3055\u308c\u3066\u3044\u308b\u3002 \u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8efd\u9396\uff08\u3081\u3093\u3048\u304d\u30b0\u30ed\u30d6\u30ea\u30f3\u3051\u3044\u3055\u3001\u82f1: immunoglobulin light chain\uff09\u306f\u3001\u6297\u4f53\uff08\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\uff09\u306e\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3067\u3042\u308b\u3002\u5178\u578b\u7684\u306a\u6297\u4f53\u306f\u30012\u3064\u306e\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\uff08Ig\uff09\u91cd\u9396\u30682\u3064\u306e\u8efd\u9396\u304b\u3089\u69cb\u6210\u3055\u308c\u308b\u3002 \u30d2\u30c8\u306e\u8efd\u9396\u306b\u306f2\u3064\u306e\u30bf\u30a4\u30d7\u304c\u5b58\u5728\u3059\u308b \u6297\u4f53\u306fB\u7d30\u80de\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u3001\u5404\u7d30\u80de\u306f\u305f\u30601\u3064\u306e\u30af\u30e9\u30b9\u306e\u8efd\u9396\u3092\u767a\u73fe\u3059\u308b\u3002\u8efd\u9396\u306e\u30af\u30e9\u30b9\u304c\u3044\u3063\u305f\u3093\u8a2d\u5b9a\u3055\u308c\u308b\u3068\u3001\u305d\u306e\u30af\u30e9\u30b9\u306fB\u7d30\u80de\u306e\u4e00\u751f\u3092\u901a\u3058\u3066\u56fa\u5b9a\u3055\u308c\u308b\u3002\u30dd\u30ea\u30af\u30ed\u30fc\u30ca\u30eb\u904a\u96e2\u8efd\u9396\u30a2\u30c3\u30bb\u30a4\u306b\u3088\u308b\u3068\u3001\u5065\u5e38\u4eba\u3067\u306e\u8840\u6e05\u4e2d\u306e\u03bb\u9396\u306b\u5bfe\u3059\u308b\u03ba\u9396\u306e\u6b63\u5e38\u306a\u6bd4\u7387\u306f0.26\u304b\u30891.65\u306e\u7bc4\u56f2\u3067\u3042\u308b[1]\u3002\u3053\u3053\u304b\u3089\u306e\u5927\u304d\u306a\u4e56\u96e2\u306f\u65b0\u751f\u7269\u306e\u5fb4\u5019\u3067\u3042\u308b\u3002\u03ba\u9396\u3068\u03bb\u9396\u306e\u53cc\u65b9\u304c\u6b63\u5e38\u306a\u6bd4\u7387\u3092\u7dad\u6301\u3057\u306a\u304c\u3089\u6bd4\u4f8b\u3057\u3066\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u308c\u306f\u591a\u304f\u306e\u5834\u5408\u3001\u8840\u7403\u7d30\u80de\u306e\u75be\u60a3\u4ee5\u5916\u306e\u8981\u56e0\u3001\u305f\u3068\u3048\u3070\u814e\u81d3\u75c5\u306a\u3069\u306e\u5fb4\u5019\u3067\u3042\u308b\u3002 \u4ed6\u306e\u52d5\u7269[\u7de8\u96c6] \u56db\u80a2\u52d5\u7269\u306b\u304a\u3051\u308b\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8efd\u9396\u306e\u907a\u4f1d\u5b50\u306f\u3001\u03ba\u3001\u03bb\u3001\u03c3\u3068\u3044\u30463\u3064\u306e\u7570\u306a\u308b\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u985e\u3055\u308c\u308b\u3002\u03ba\u3001\u03bb\u3001\u03c3\u30a2\u30a4\u30bd\u30bf\u30a4\u30d7\u306e\u591a\u69d8\u6027\u306f\u56db\u80a2\u52d5\u7269\u306e\u653e\u6563\u9032\u5316\u306b\u5148\u3093\u3058\u3066\u751f\u3058\u305f\u3082\u306e\u3067\u3042\u308b\u3002\u03c3\u30a2\u30a4\u30bd\u30bf\u30a4\u30d7\u306f\u4e21\u751f\u985e\u7cfb\u7d71\u306e\u9032\u5316\u5f8c\u3001\u722c\u866b\u985e\u7cfb\u7d71\u306e\u51fa\u73fe\u524d\u306b\u5931\u308f\u308c\u305f[2]\u3002 \u4e0b\u7b49\u810a\u690e\u52d5\u7269\u3067\u306f\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u8efd\u9396\u3082\u5b58\u5728\u3057\u3001\u8edf\u9aa8\u9b5a\u985e\u3084\u771f\u9aa8\u985e\u306b\u306f\u03b9\u9396\u304c\u5b58\u5728\u3059\u308b[3][4]\u3002 \u30e9\u30af\u30c0\u79d1\u306f\u54fa\u4e73\u985e\u306e\u306a\u304b\u3067\u3082\u72ec\u7279\u3067\u3042\u308a\u30012\u3064\u306e\u91cd\u9396\u3092\u542b\u3080\u304c\u8efd\u9396\u3092\u6301\u305f\u306a\u3044\u6a5f\u80fd\u7684\u6297\u4f53\u3082\u6709\u3059\u308b[5]\u3002 \u30b5\u30e1\u306f\u7372\u5f97\u514d\u75ab\u7cfb\u306e\u4e00\u90e8\u3068\u3057\u3066\u3001IgNAR\uff08immunoglobulin new antigen receptor)\uff09\u3068\u547c\u3070\u308c\u308b\u6a5f\u80fd\u7684\u306a\u91cd\u9396\u30db\u30e2\u4e8c\u91cf\u4f53\u578b\u6297\u4f53\u69d8\u5206\u5b50\u3092\u6301\u3063\u3066\u3044\u308b\u3002\u30e9\u30af\u30c0\u79d1\u306e\u91cd\u9396\u6297\u4f53\u304c\u9032\u5316\u306e\u904e\u7a0b\u3067\u8efd\u9396\u306e\u30d1\u30fc\u30c8\u30ca\u30fc\u3092\u5931\u3063\u305f\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u306e\u306b\u5bfe\u3057\u3001IgNAR\u306f\u3082\u3068\u3082\u3068\u7d50\u5408\u3059\u308b\u8efd\u9396\u3092\u6301\u3063\u3066\u3044\u306a\u304b\u3063\u305f\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b[6][7]\u3002 \u5178\u578b\u7684\u306a\u6297\u4f53\u306b\u306f1\u3064\u306e\u30bf\u30a4\u30d7\u306e\u8efd\u9396\u306e\u307f\u304c\u5b58\u5728\u3057\u3001\u500b\u3005\u306e\u6297\u4f53\u306e2\u3064\u306e\u8efd\u9396\u306f\u540c\u4e00\u3067\u3042\u308b\u3002 \u5404\u8efd\u9396\u306f2\u3064\u306e\u30bf\u30f3\u30c7\u30e0\u306a\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u30c9\u30e1\u30a4\u30f3\u304b\u3089\u69cb\u6210\u3055\u308c\u308b\u3002 1\u3064\u306e\u5b9a\u5e38\u30c9\u30e1\u30a4\u30f3\uff08CL\uff09 1\u3064\u306e\u53ef\u5909\u30c9\u30e1\u30a4\u30f3\uff08VL\uff09-","datePublished":"2020-03-26","dateModified":"2020-03-26","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/jp\/wiki\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/jp\/wiki\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/b\/bb\/AntibodyChains.svg\/220px-AntibodyChains.svg.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/b\/bb\/AntibodyChains.svg\/220px-AntibodyChains.svg.png","height":"171","width":"220"},"url":"https:\/\/wiki.edu.vn\/jp\/wiki\/2020\/03\/26\/%e5%85%8d%e7%96%ab%e3%82%b0%e3%83%ad%e3%83%96%e3%83%aa%e3%83%b3%e8%bb%bd%e9%8e%96-wikipedia\/","about":["Wiki"],"wordCount":3447,"articleBody":" \u5178\u578b\u7684\u306a\u6297\u4f53\u306e\u6a21\u5f0f\u56f3\u30022\u3064\u306eIg\u91cd\u9396\uff08\u9752\uff09\u3068\u8efd\u9396\uff08\u7dd1\uff09\u304c\u30b8\u30b9\u30eb\u30d5\u30a3\u30c9\u7d50\u5408\u306b\u3088\u3063\u3066\u9023\u7d50\u3055\u308c\u3066\u3044\u308b\u3002\u5b9a\u5e38\u9818\u57df\uff08C\uff09\u3068\u53ef\u5909\u9818\u57df\uff08V\uff09\u304c\u793a\u3055\u308c\u3066\u3044\u308b\u3002 \u6297\u4f53\u5206\u5b50\u306e\u30ea\u30dc\u30f3\u56f3\u30022\u3064\u306e\u91cd\u9396\u306f\u8d64\u3068\u9752\u3067\u30012\u3064\u306e\u8efd\u9396\u306f\u7dd1\u3068\u9ec4\u3067\u793a\u3055\u308c\u3066\u3044\u308b\u3002\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8efd\u9396\uff08\u3081\u3093\u3048\u304d\u30b0\u30ed\u30d6\u30ea\u30f3\u3051\u3044\u3055\u3001\u82f1: immunoglobulin light chain\uff09\u306f\u3001\u6297\u4f53\uff08\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\uff09\u306e\u30b5\u30d6\u30e6\u30cb\u30c3\u30c8\u3067\u3042\u308b\u3002\u5178\u578b\u7684\u306a\u6297\u4f53\u306f\u30012\u3064\u306e\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\uff08Ig\uff09\u91cd\u9396\u30682\u3064\u306e\u8efd\u9396\u304b\u3089\u69cb\u6210\u3055\u308c\u308b\u3002 \u30d2\u30c8\u306e\u8efd\u9396\u306b\u306f2\u3064\u306e\u30bf\u30a4\u30d7\u304c\u5b58\u5728\u3059\u308b \u6297\u4f53\u306fB\u7d30\u80de\u306b\u3088\u3063\u3066\u7523\u751f\u3055\u308c\u3001\u5404\u7d30\u80de\u306f\u305f\u30601\u3064\u306e\u30af\u30e9\u30b9\u306e\u8efd\u9396\u3092\u767a\u73fe\u3059\u308b\u3002\u8efd\u9396\u306e\u30af\u30e9\u30b9\u304c\u3044\u3063\u305f\u3093\u8a2d\u5b9a\u3055\u308c\u308b\u3068\u3001\u305d\u306e\u30af\u30e9\u30b9\u306fB\u7d30\u80de\u306e\u4e00\u751f\u3092\u901a\u3058\u3066\u56fa\u5b9a\u3055\u308c\u308b\u3002\u30dd\u30ea\u30af\u30ed\u30fc\u30ca\u30eb\u904a\u96e2\u8efd\u9396\u30a2\u30c3\u30bb\u30a4\u306b\u3088\u308b\u3068\u3001\u5065\u5e38\u4eba\u3067\u306e\u8840\u6e05\u4e2d\u306e\u03bb\u9396\u306b\u5bfe\u3059\u308b\u03ba\u9396\u306e\u6b63\u5e38\u306a\u6bd4\u7387\u306f0.26\u304b\u30891.65\u306e\u7bc4\u56f2\u3067\u3042\u308b[1]\u3002\u3053\u3053\u304b\u3089\u306e\u5927\u304d\u306a\u4e56\u96e2\u306f\u65b0\u751f\u7269\u306e\u5fb4\u5019\u3067\u3042\u308b\u3002\u03ba\u9396\u3068\u03bb\u9396\u306e\u53cc\u65b9\u304c\u6b63\u5e38\u306a\u6bd4\u7387\u3092\u7dad\u6301\u3057\u306a\u304c\u3089\u6bd4\u4f8b\u3057\u3066\u5897\u52a0\u3059\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u3053\u308c\u306f\u591a\u304f\u306e\u5834\u5408\u3001\u8840\u7403\u7d30\u80de\u306e\u75be\u60a3\u4ee5\u5916\u306e\u8981\u56e0\u3001\u305f\u3068\u3048\u3070\u814e\u81d3\u75c5\u306a\u3069\u306e\u5fb4\u5019\u3067\u3042\u308b\u3002\u4ed6\u306e\u52d5\u7269[\u7de8\u96c6]\u56db\u80a2\u52d5\u7269\u306b\u304a\u3051\u308b\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8efd\u9396\u306e\u907a\u4f1d\u5b50\u306f\u3001\u03ba\u3001\u03bb\u3001\u03c3\u3068\u3044\u30463\u3064\u306e\u7570\u306a\u308b\u30b0\u30eb\u30fc\u30d7\u306b\u5206\u985e\u3055\u308c\u308b\u3002\u03ba\u3001\u03bb\u3001\u03c3\u30a2\u30a4\u30bd\u30bf\u30a4\u30d7\u306e\u591a\u69d8\u6027\u306f\u56db\u80a2\u52d5\u7269\u306e\u653e\u6563\u9032\u5316\u306b\u5148\u3093\u3058\u3066\u751f\u3058\u305f\u3082\u306e\u3067\u3042\u308b\u3002\u03c3\u30a2\u30a4\u30bd\u30bf\u30a4\u30d7\u306f\u4e21\u751f\u985e\u7cfb\u7d71\u306e\u9032\u5316\u5f8c\u3001\u722c\u866b\u985e\u7cfb\u7d71\u306e\u51fa\u73fe\u524d\u306b\u5931\u308f\u308c\u305f[2]\u3002\u4e0b\u7b49\u810a\u690e\u52d5\u7269\u3067\u306f\u4ed6\u306e\u30bf\u30a4\u30d7\u306e\u8efd\u9396\u3082\u5b58\u5728\u3057\u3001\u8edf\u9aa8\u9b5a\u985e\u3084\u771f\u9aa8\u985e\u306b\u306f\u03b9\u9396\u304c\u5b58\u5728\u3059\u308b[3][4]\u3002\u30e9\u30af\u30c0\u79d1\u306f\u54fa\u4e73\u985e\u306e\u306a\u304b\u3067\u3082\u72ec\u7279\u3067\u3042\u308a\u30012\u3064\u306e\u91cd\u9396\u3092\u542b\u3080\u304c\u8efd\u9396\u3092\u6301\u305f\u306a\u3044\u6a5f\u80fd\u7684\u6297\u4f53\u3082\u6709\u3059\u308b[5]\u3002 \u30b5\u30e1\u306f\u7372\u5f97\u514d\u75ab\u7cfb\u306e\u4e00\u90e8\u3068\u3057\u3066\u3001IgNAR\uff08immunoglobulin new antigen receptor)\uff09\u3068\u547c\u3070\u308c\u308b\u6a5f\u80fd\u7684\u306a\u91cd\u9396\u30db\u30e2\u4e8c\u91cf\u4f53\u578b\u6297\u4f53\u69d8\u5206\u5b50\u3092\u6301\u3063\u3066\u3044\u308b\u3002\u30e9\u30af\u30c0\u79d1\u306e\u91cd\u9396\u6297\u4f53\u304c\u9032\u5316\u306e\u904e\u7a0b\u3067\u8efd\u9396\u306e\u30d1\u30fc\u30c8\u30ca\u30fc\u3092\u5931\u3063\u305f\u3082\u306e\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u306e\u306b\u5bfe\u3057\u3001IgNAR\u306f\u3082\u3068\u3082\u3068\u7d50\u5408\u3059\u308b\u8efd\u9396\u3092\u6301\u3063\u3066\u3044\u306a\u304b\u3063\u305f\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b[6][7]\u3002\u5178\u578b\u7684\u306a\u6297\u4f53\u306b\u306f1\u3064\u306e\u30bf\u30a4\u30d7\u306e\u8efd\u9396\u306e\u307f\u304c\u5b58\u5728\u3057\u3001\u500b\u3005\u306e\u6297\u4f53\u306e2\u3064\u306e\u8efd\u9396\u306f\u540c\u4e00\u3067\u3042\u308b\u3002\u5404\u8efd\u9396\u306f2\u3064\u306e\u30bf\u30f3\u30c7\u30e0\u306a\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u30c9\u30e1\u30a4\u30f3\u304b\u3089\u69cb\u6210\u3055\u308c\u308b\u30021\u3064\u306e\u5b9a\u5e38\u30c9\u30e1\u30a4\u30f3\uff08CL\uff091\u3064\u306e\u53ef\u5909\u30c9\u30e1\u30a4\u30f3\uff08VL\uff09- \u6297\u539f\u3078\u306e\u7d50\u5408\u306b\u91cd\u8981\u3067\u3042\u308b\u3002\u8efd\u9396\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u304a\u3088\u305d\u306e\u9577\u3055\u306f211\u30a2\u30df\u30ce\u9178\u304b\u3089217\u30a2\u30df\u30ce\u9178\u3067\u3042\u308b[3]\u3002\u5b9a\u5e38\u9818\u57df\u306f\u8efd\u9396\u306e\u30af\u30e9\u30b9\uff08\u03ba\u3001\u03bb\uff09\u3092\u6c7a\u5b9a\u3059\u308b[8]\u3002\u03bb\u30af\u30e9\u30b9\u306b\u306f4\u3064\u306e\u30b5\u30d6\u30bf\u30a4\u30d7\uff08\u03bb1\u3001\u03bb2\u3001\u03bb3\u3001\u03bb7\uff09\u304c\u5b58\u5728\u3059\u308b[8]\u3002\u30ea\u30f3\u30d1\u7cfb\u306e\u500b\u3005\u306eB\u7d30\u80de\u306f\u03ba\u9396\u307e\u305f\u306f\u03bb\u9396\u306e\u8efd\u9396\u306e\u3044\u305a\u308c\u304b\u3092\u6301\u3063\u3066\u304a\u308a\u3001\u53cc\u65b9\u3092\u6301\u3063\u3066\u3044\u308b\u3053\u3068\u306f\u6c7a\u3057\u3066\u306a\u3044\u3002\u514d\u75ab\u7d44\u7e54\u5316\u5b66\u7684\u624b\u6cd5\u3092\u7528\u3044\u308b\u3053\u3068\u3067\u3001\u03ba\u9396\u3068\u03bb\u9396\u3092\u767a\u73fe\u3057\u3066\u3044\u308bB\u7d30\u80de\u306e\u76f8\u5bfe\u7684\u5b58\u5728\u91cf\u3092\u6c7a\u5b9a\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u308b\u3002\u30ea\u30f3\u30d1\u7bc0\u3084\u540c\u69d8\u306e\u7d44\u7e54\u304c\u53cd\u5fdc\u6027\uff08\u82f1\u8a9e\u7248\uff09\u307e\u305f\u306f\u826f\u6027\u306e\u5834\u5408\u306b\u306f\u3001\u03ba\u9396\u967d\u6027\u7d30\u80de\u3068\u03bb\u9396\u967d\u6027\u7d30\u80de\u304c\u6df7\u5728\u3057\u3066\u3044\u308b\u3002\u3057\u304b\u3057\u306a\u304c\u3089\u3001\u4e00\u65b9\u306e\u30bf\u30a4\u30d7\u306e\u8efd\u9396\u304c\u4ed6\u65b9\u3088\u308a\u3082\u306f\u308b\u304b\u306b\u591a\u304f\u5b58\u5728\u3057\u3066\u3044\u308b\u5834\u5408\u306b\u306f\u3001\u305d\u308c\u3089\u306f\u3059\u3079\u3066\u5c0f\u3055\u306a\u30af\u30ed\u30fc\u30f3\u96c6\u56e3\u306b\u7531\u6765\u3057\u3066\u3044\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u304f\u3001B\u7d30\u80de\u30ea\u30f3\u30d1\u816b\uff08\u82f1\u8a9e\u7248\uff09\u306a\u3069\u60aa\u6027\u3067\u3042\u308b\u53ef\u80fd\u6027\u3092\u793a\u3057\u3066\u3044\u308b[9]\u3002\u591a\u767a\u6027\u9aa8\u9ac4\u816b\u306a\u3069\u3001\u816b\u760d\u6027\u5f62\u8cea\u7d30\u80de\u3067\u7523\u751f\u3055\u308c\u308bIg\u8efd\u9396\u306f\u30d9\u30f3\u30b9\u30fb\u30b8\u30e7\u30fc\u30f3\u30ba\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u82f1\u8a9e\u7248\uff09\u3068\u547c\u3070\u308c\u308b\u3002\u904a\u96e2Ig\u8efd\u9396\u30ec\u30d9\u30eb\u306e\u5897\u52a0\u306f\u3055\u307e\u3056\u307e\u306a\u708e\u75c7\u6027\u75be\u60a3\u3067\u3082\u691c\u51fa\u3055\u308c\u308b\u3002\u30ea\u30f3\u30d1\u816b\u306e\u60a3\u8005\u3067\u307f\u3089\u308c\u308b\u5897\u52a0\u3068\u306f\u5bfe\u7167\u7684\u306b\u3001\u708e\u75c7\u6027\u75be\u60a3\u3067\u5897\u52a0\u3059\u308bIg\u8efd\u9396\u306f\u30dd\u30ea\u30af\u30ed\u30fc\u30ca\u30eb\u3067\u3042\u308b\u3002\u3053\u308c\u3089\u306eIg\u8efd\u9396\u306f\u80a5\u6e80\u7d30\u80de\u306b\u7d50\u5408\u3057\u3001\u305d\u306e\u6297\u539f\u7d50\u5408\u80fd\u3092\u5229\u7528\u3057\u3066\u80a5\u6e80\u7d30\u80de\u306e\u6d3b\u6027\u5316\u3092\u4fc3\u9032\u3059\u308b\u3053\u3068\u304c\u793a\u3055\u308c\u3066\u3044\u308b[10]\u3002\u80a5\u6e80\u7d30\u80de\u306e\u6d3b\u6027\u5316\u306f\u3055\u307e\u3056\u307e\u306a\u708e\u75c7\u6027\u30e1\u30c7\u30a3\u30a8\u30fc\u30bf\u30fc\u306e\u653e\u51fa\u3092\u5f15\u304d\u8d77\u3053\u3057\u3001\u708e\u75c7\u6027\u75be\u60a3\u306e\u767a\u75c7\u306b\u5bc4\u4e0e\u3059\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002Ig\u8efd\u9396\u306f\u80a5\u6e80\u7d30\u80de\u3060\u3051\u3067\u306a\u304f\u597d\u4e2d\u7403[11]\u3084\u5f8c\u6839\u795e\u7d4c\u7bc0\u306e\u795e\u7d4c\u7d30\u80de[12]\u3092\u6d3b\u6027\u5316\u3059\u308b\u3053\u3068\u3082\u793a\u3055\u308c\u3066\u304a\u308a\u3001\u708e\u75c7\u6027\u75be\u60a3\u306b\u304a\u3051\u308b\u30e1\u30c7\u30a3\u30a8\u30fc\u30bf\u30fc\u3068\u3057\u3066\u306e\u5f79\u5272\u306e\u53ef\u80fd\u6027\u306f\u5e83\u304c\u3063\u3066\u3044\u308b\u3002^ \u201cSerum reference intervals and diagnostic ranges for free kappa and free lambda immunoglobulin light chains: relative sensitivity for detection of monoclonal light chains\u201d. Clin Chem 48 (9): 1437\u201344. (2001). doi:10.1093\/clinchem\/48.9.1437. PMID\u00a012194920.\u00a0^ \u201cEvolutionary redefinition of immunoglobulin light chain isotypes in tetrapods using molecular markers\u201d. Proc Natl Acad Sci U S A 105 (43): 16647\u201352. (2008). doi:10.1073\/pnas.0808800105. PMC\u00a02575474. PMID\u00a018940927. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC2575474\/.\u00a0^ a b Janeway CA, Jr. (2001). Immunobiology. (5th ed.). Garland Publishing. ISBN\u00a00-8153-3642-X. (electronic full text via NCBI Bookshelf)\u00a0^ IMGT Index Archived 2007-04-27 at the Wayback Machine. Antibodies (or Immunoglobulins).^ \u201cNaturally occurring antibodies devoid of light chains\u201d. Nature 363 (6428): 446\u20138. (1993). doi:10.1038\/363446a0. PMID\u00a08502296.\u00a0^ Flajnik, MF; Deschacht, N; Muyldermans, S (2011). \u201cA Case Of Convergence: Why Did a Simple Alternative to Canonical Antibodies Arise in Sharks and Camels?\u201d. PLOS Biology 9 (8): e1001120. doi:10.1371\/journal.pbio.1001120. PMC\u00a03149040. PMID\u00a021829328. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3149040\/.\u00a0^ Greenberg, A. S.; Avila, D.; Hughes, M.; Hughes, A.; McKinney, E. C.; Flajnik, M. F. (1995-03-09). \u201cA new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks\u201d. Nature 374 (6518): 168\u2013173. doi:10.1038\/374168a0. ISSN\u00a00028-0836. PMID\u00a07877689.\u00a0^ a b Owen, Judith A.; Punt, Jenni; Stranford, Sharon (2013). Kuby Immunology. New York, NY: W. H. Freeman and Company. pp.\u00a085. ISBN\u00a09781429219198\u00a0^ Leong, Anthony S-Y; Cooper, Kumarason; Leong, F Joel W-M (2003). Manual of Diagnostic Cytology (2 ed.). Greenwich Medical Media, Ltd.. pp.\u00a0283\u2013285. ISBN\u00a01-84110-100-1\u00a0^ Redegeld, Frank A.; van der Heijden, Maurice W.; Kool, Mirjam; Heijdra, Bianca M.; Garssen, Johan; Kraneveld, Aletta D.; Van Loveren, Henk; Roholl, Paul et al. (2002-07). \u201cImmunoglobulin-free light chains elicit immediate hypersensitivity-like responses\u201d. Nature Medicine 8 (7): 694\u2013701. doi:10.1038\/nm722. ISSN\u00a01078-8956. PMID\u00a012068287. https:\/\/pubmed.ncbi.nlm.nih.gov\/12068287.\u00a0^ Braber, Saskia; Thio, Marco; Blokhuis, Bart R.; Henricks, Paul A. J.; Koelink, Pim J.; Groot Kormelink, Tom; Bezemer, Gillina F. G.; Kerstjens, Huib A. M. et al. (2012-04-15). \u201cAn association between neutrophils and immunoglobulin free light chains in the pathogenesis of chronic obstructive pulmonary disease\u201d. American Journal of Respiratory and Critical Care Medicine 185 (8): 817\u2013824. doi:10.1164\/rccm.201104-0761OC. ISSN\u00a01535-4970. PMID\u00a022227380. https:\/\/pubmed.ncbi.nlm.nih.gov\/22227380.\u00a0^ Rijnierse, Anneke; Kroese, Alfons B. A.; Redegeld, Frank A.; Blokhuis, Bart R. J.; van der Heijden, Maurice W.; Koster, Andries S.; Timmermans, Jean-Pierre; Nijkamp, Frans P. et al. (2009-03-31). \u201cImmunoglobulin-free light chains mediate antigen-specific responses of murine dorsal root ganglion neurons\u201d. Journal of Neuroimmunology 208 (1-2): 80\u201386. doi:10.1016\/j.jneuroim.2009.01.008. ISSN\u00a01872-8421. PMID\u00a019232443. https:\/\/pubmed.ncbi.nlm.nih.gov\/19232443.\u00a0\u95a2\u9023\u9805\u76ee[\u7de8\u96c6]\u5916\u90e8\u30ea\u30f3\u30af[\u7de8\u96c6]"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki\/2020\/03\/26\/%e5%85%8d%e7%96%ab%e3%82%b0%e3%83%ad%e3%83%96%e3%83%aa%e3%83%b3%e8%bb%bd%e9%8e%96-wikipedia\/#breadcrumbitem","name":"\u514d\u75ab\u30b0\u30ed\u30d6\u30ea\u30f3\u8efd\u9396 – Wikipedia"}}]}]