[{"@context":"http:\/\/schema.org\/","@type":"BlogPosting","@id":"https:\/\/wiki.edu.vn\/jp\/wiki2\/2019\/08\/28\/%e3%83%92%e3%83%88%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9hku1-wikipedia\/#BlogPosting","mainEntityOfPage":"https:\/\/wiki.edu.vn\/jp\/wiki2\/2019\/08\/28\/%e3%83%92%e3%83%88%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9hku1-wikipedia\/","headline":"\u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1 – Wikipedia","name":"\u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1 – Wikipedia","description":"\u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1 \u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1\u306e\u611f\u67d3\u306b\u3088\u308a\u3001\u5408\u80de\u4f53\u3092\u5f62\u6210\u3057\u305fII\u578b\u80ba\u80de\u4e0a\u76ae\u7d30\u80de \u5206\u985e \u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1\uff08HCoV-HKU1,Human coronavirus HKU1)\u306f\u3001\u30cb\u30c9\u30a6\u30a4\u30eb\u30b9\u76ee\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u79d1\u30d9\u30fc\u30bf\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u5c5e\u30a8\u30f3\u30d9\u30b3\u30a6\u30a4\u30eb\u30b9\u4e9c\u5c5e\u306b\u5c5e\u3059\u308bRNA\u30a6\u30a4\u30eb\u30b9\u3067\u3042\u308b[1]\u3002\u30d2\u30c8\u306b\u611f\u67d3\u3059\u308b\u3068\u98a8\u90aa\u75c7\u72b6\u3001\u60aa\u5316\u3059\u308b\u3068\u80ba\u708e\u3001\u6c17\u7ba1\u652f\u708e\u3092\u767a\u75c7\u3059\u308b[2]\u3002 \u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\uff08\u819c\u69cb\u9020\uff09\u3092\u6301\u3064\u4e00\u672c\u9396\u30d7\u30e9\u30b9\u9396RNA\u30a6\u30a4\u30eb\u30b9\u3067\u3042\u308a\u3001N-\u30a2\u30bb\u30c1\u30eb-9-O-\u30a2\u30bb\u30c1\u30eb\u30ce\u30a4\u30e9\u30df\u30f3\u9178\u53d7\u5bb9\u4f53\u3068\u7d50\u5408\u3057\u3066\u5bbf\u4e3b\u7d30\u80de\u306b\u4fb5\u5165\u3059\u308b[3]\u3002\u30d8\u30de\u30b0\u30eb\u30c1\u30cb\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\uff08HE\uff09\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6301\u3064[1] 2005\u5e741\u6708\u306b\u9999\u6e2f\u306e\u60a3\u80052\u540d\u306e\u75be\u60a3\u3067\u767a\u898b\u3055\u308c\u305f[4][5]\u3002\u305d\u306e\u5f8c\u306e\u7814\u7a76\u3067\u3001\u3059\u3067\u306b\u4e16\u754c\u306b\u8513\u5ef6\u3057\u3001\u4ee5\u524d\u306b\u3082\u767a\u75c7\u4f8b\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002 \u95a2\u9023\u9805\u76ee[\u7de8\u96c6] \u30bf\u30b1\u30b3\u30a6\u30e2\u30ea\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU4\uff08Tylonycteris bat coronavirus HKU4\uff09 \u30eb\u30fc\u30bb\u30c3\u30c8\u30b3\u30a6\u30e2\u30ea\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU9\uff08Rousettus bat coronavirus HKU9) \u51fa\u5178[\u7de8\u96c6] ^ a","datePublished":"2019-08-28","dateModified":"2019-08-28","author":{"@type":"Person","@id":"https:\/\/wiki.edu.vn\/jp\/wiki2\/author\/lordneo\/#Person","name":"lordneo","url":"https:\/\/wiki.edu.vn\/jp\/wiki2\/author\/lordneo\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/c9645c498c9701c88b89b8537773dd7c?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Enzyklop\u00e4die","logo":{"@type":"ImageObject","@id":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","url":"https:\/\/wiki.edu.vn\/wiki4\/wp-content\/uploads\/2023\/08\/download.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/8a\/Coronavirus-HKU1.png\/220px-Coronavirus-HKU1.png","url":"https:\/\/upload.wikimedia.org\/wikipedia\/commons\/thumb\/8\/8a\/Coronavirus-HKU1.png\/220px-Coronavirus-HKU1.png","height":"176","width":"220"},"url":"https:\/\/wiki.edu.vn\/jp\/wiki2\/2019\/08\/28\/%e3%83%92%e3%83%88%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9hku1-wikipedia\/","about":["Wiki"],"wordCount":1953,"articleBody":"\u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1 \u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1\u306e\u611f\u67d3\u306b\u3088\u308a\u3001\u5408\u80de\u4f53\u3092\u5f62\u6210\u3057\u305fII\u578b\u80ba\u80de\u4e0a\u76ae\u7d30\u80de\u5206\u985e  \u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1\uff08HCoV-HKU1,Human coronavirus HKU1)\u306f\u3001\u30cb\u30c9\u30a6\u30a4\u30eb\u30b9\u76ee\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u79d1\u30d9\u30fc\u30bf\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9\u5c5e\u30a8\u30f3\u30d9\u30b3\u30a6\u30a4\u30eb\u30b9\u4e9c\u5c5e\u306b\u5c5e\u3059\u308bRNA\u30a6\u30a4\u30eb\u30b9\u3067\u3042\u308b[1]\u3002\u30d2\u30c8\u306b\u611f\u67d3\u3059\u308b\u3068\u98a8\u90aa\u75c7\u72b6\u3001\u60aa\u5316\u3059\u308b\u3068\u80ba\u708e\u3001\u6c17\u7ba1\u652f\u708e\u3092\u767a\u75c7\u3059\u308b[2]\u3002\u30a8\u30f3\u30d9\u30ed\u30fc\u30d7\uff08\u819c\u69cb\u9020\uff09\u3092\u6301\u3064\u4e00\u672c\u9396\u30d7\u30e9\u30b9\u9396RNA\u30a6\u30a4\u30eb\u30b9\u3067\u3042\u308a\u3001N-\u30a2\u30bb\u30c1\u30eb-9-O-\u30a2\u30bb\u30c1\u30eb\u30ce\u30a4\u30e9\u30df\u30f3\u9178\u53d7\u5bb9\u4f53\u3068\u7d50\u5408\u3057\u3066\u5bbf\u4e3b\u7d30\u80de\u306b\u4fb5\u5165\u3059\u308b[3]\u3002\u30d8\u30de\u30b0\u30eb\u30c1\u30cb\u30f3\u30a8\u30b9\u30c6\u30e9\u30fc\u30bc\uff08HE\uff09\u7cd6\u30bf\u30f3\u30d1\u30af\u8cea\u3092\u6301\u3064[1]  2005\u5e741\u6708\u306b\u9999\u6e2f\u306e\u60a3\u80052\u540d\u306e\u75be\u60a3\u3067\u767a\u898b\u3055\u308c\u305f[4][5]\u3002\u305d\u306e\u5f8c\u306e\u7814\u7a76\u3067\u3001\u3059\u3067\u306b\u4e16\u754c\u306b\u8513\u5ef6\u3057\u3001\u4ee5\u524d\u306b\u3082\u767a\u75c7\u4f8b\u304c\u3042\u308b\u3053\u3068\u304c\u308f\u304b\u3063\u305f\u3002\u95a2\u9023\u9805\u76ee[\u7de8\u96c6]\u30bf\u30b1\u30b3\u30a6\u30e2\u30ea\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU4\uff08Tylonycteris bat coronavirus HKU4\uff09\u30eb\u30fc\u30bb\u30c3\u30c8\u30b3\u30a6\u30e2\u30ea\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU9\uff08Rousettus bat coronavirus HKU9)\u51fa\u5178[\u7de8\u96c6]^ a b Woo, Patrick C. Y.; Huang, Yi; Lau, Susanna K. P.; Yuen, Kwok-Yung (2010-08-24). \u201cCoronavirus Genomics and Bioinformatics Analysis\u201d. Viruses 2 (8):  1804\u20131820. doi:10.3390\/v2081803. ISSN\u00a01999-4915. PMC\u00a03185738. PMID\u00a021994708. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC3185738\/. “In all members of Betacoronavirus subgroup A, a haemagglutinin esterase (HE) gene, which encodes a glycoprotein with neuraminate O-acetyl-esterase activity and the active site FGDS, is present downstream to ORF1ab and upstream to S gene (Figure 1).”\u00a0^ Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). \u201cHuman Coronaviruses: A Review of Virus\u2013Host Interactions\u201d. Diseases 4 (3):  26. doi:10.3390\/diseases4030026. ISSN\u00a02079-9721. PMC\u00a05456285. PMID\u00a028933406. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5456285\/. “See Table 1.”\u00a0^ Lim, Yvonne Xinyi; Ng, Yan Ling; Tam, James P.; Liu, Ding Xiang (2016-07-25). \u201cHuman Coronaviruses: A Review of Virus\u2013Host Interactions\u201d. Diseases 4 (3):  26. doi:10.3390\/diseases4030026. ISSN\u00a02079-9721. PMC\u00a05456285. PMID\u00a028933406. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5456285\/. “See Table 1.”\u00a0^ Lau, S. K. P.; Woo, P. C. Y.; Yip, C. C. Y.; Tse, H.; Tsoi, H.-w.; Cheng, V. C. C.; Lee, P.; Tang, B. S. F. et al. (2006). \u201cCoronavirus HKU1 and Other Coronavirus Infections in Hong Kong\u201d. Journal of Clinical Microbiology 44 (6):  2063\u201371. doi:10.1128\/JCM.02614-05. PMC\u00a01489438. PMID\u00a016757599. https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC1489438\/.\u00a0^ Vabret, A.; Dina, J.; Gouarin, S.; Petitjean, J.; Corbet, S.; Freymuth, F. (2006). \u201cDetection of the New Human Coronavirus HKU1: A Report of 6 Cases\u201d. Clinical Infectious Diseases 42 (5):  634\u20139. doi:10.1086\/500136. PMID\u00a016447108.\u00a0"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki2\/#breadcrumbitem","name":"Enzyklop\u00e4die"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/wiki.edu.vn\/jp\/wiki2\/2019\/08\/28\/%e3%83%92%e3%83%88%e3%82%b3%e3%83%ad%e3%83%8a%e3%82%a6%e3%82%a4%e3%83%ab%e3%82%b9hku1-wikipedia\/#breadcrumbitem","name":"\u30d2\u30c8\u30b3\u30ed\u30ca\u30a6\u30a4\u30eb\u30b9HKU1 – Wikipedia"}}]}]